1,953 research outputs found
Kink stability, propagation, and length scale competition in the periodically modulated sine-Gordon equation
We have examined the dynamical behavior of the kink solutions of the
one-dimensional sine-Gordon equation in the presence of a spatially periodic
parametric perturbation. Our study clarifies and extends the currently
available knowledge on this and related nonlinear problems in four directions.
First, we present the results of a numerical simulation program which are not
compatible with the existence of a radiative threshold, predicted by earlier
calculations. Second, we carry out a perturbative calculation which helps
interpret those previous predictions, enabling us to understand in depth our
numerical results. Third, we apply the collective coordinate formalism to this
system and demonstrate numerically that it accurately reproduces the observed
kink dynamics. Fourth, we report on a novel occurrence of length scale
competition in this system and show how it can be understood by means of linear
stability analysis. Finally, we conclude by summarizing the general physical
framework that arises from our study.Comment: 19 pages, REVTeX 3.0, 24 figures available from A S o
Lengthscales and Cooperativity in DNA Bubble Formation
It appears that thermally activated DNA bubbles of different sizes play
central roles in important genetic processes. Here we show that the probability
for the formation of such bubbles is regulated by the number of soft AT pairs
in specific regions with lengths which at physiological temperatures are of the
order of (but not equal to) the size of the bubble. The analysis is based on
the Peyrard- Bishop-Dauxois model, whose equilibrium statistical properties
have been accurately calculated here with a transfer integral approach
Genioglossal muscle response to CO2 stimulation during NREM sleep
STUDY OBJECTIVES: The objective was to evaluate the responsiveness of upper airway muscles to hypercapnia with and without intrapharyngeal negative pressure during non-rapid eye movement (NREM) sleep and wakefulness. DESIGN: We assessed the genioglossal muscle response to CO2 off and on continuous positive airway pressure (CPAP) (to attenuate negative pressure) during stable NREM sleep and wakefulness in the supine position. SETTING: Laboratory of the Sleep Medicine Division, Brigham and Women's Hospital. PATIENTS OR PARTICIPANTS: Eleven normal healthy subjects. INTERVENTIONS: During wakefulness and NREM sleep, we measured genioglossal electromyography (EMG) on and off CPAP at the normal eupneic level and at levels 5 and 10 mm Hg above the awake eupneic level. MEASUREMENTS AND RESULTS: We observed that CO2 could increase upper-airway muscle activity during NREM sleep and wakefulness in the supine position with and without intrapharyngeal negative pressure. The application of nasal CPAP significantly decreased genioglossal EMG at all 3 levels of PETCO2 during NREM sleep (13.0 +/- 4.9% vs. 4.6 +/- 1.6% of maximal EMG, 14.6 +/- 5.6% vs. 7.1 +/- 2.3% of maximal EMG, and 17.3 +/- 6.3% vs. 10.2 +/- 3.1% of maximal EMG, respectively). However, the absence of negative pressure in the upper airway did not significantly affect the slope of the pharyngeal airway dilator muscle response to hypercapnia during NREM sleep (0.72 +/- 0.30% vs. 0.79 +/- 0.27% of maximal EMG per mm Hg PCO2, respectively, off and on CPAP). CONCLUSIONS: We conclude that both chemoreceptive and negative pressure reflex inputs to this upper airway dilator muscle are still active during stable NREM sleep
Strain-induced partially flat band, helical snake states, and interface superconductivity in topological crystalline insulators
Topological crystalline insulators in IV-VI compounds host novel topological
surface states consisting of multi-valley massless Dirac fermions at low
energy. Here we show that strain generically acts as an effective gauge field
on these Dirac fermions and creates pseudo-Landau orbitals without breaking
time-reversal symmetry. We predict the realization of this phenomenon in IV-VI
semiconductor heterostructures, due to a naturally occurring misfit dislocation
array at the interface that produces a periodically varying strain field.
Remarkably, the zero-energy Landau orbitals form a flat band in the vicinity of
the Dirac point, and coexist with a network of snake states at higher energy.
We propose that the high density of states of this flat band gives rise to
interface superconductivity observed in IV-VI semiconductor multilayers at
unusually high temperatures, with non-BCS behavior. Our work demonstrates a new
route to altering macroscopic electronic properties to achieve a partially flat
band, and paves the way for realizing novel correlated states of matter.Comment: Accepted by Nature Physic
Dynamics of Flux Creep in Underdoped Single Crystals of Y_1-xPr_xBa_2Cu_3O_7-d
Transport as well as magnetic relaxation properties of the mixed state were
studied on strongly underdoped Y_1-xPr_xBa_2Cu_3O_7-d crystals. We observed two
correlated phenomena - a coupling transition and a transition to quantum creep.
The distribution of transport current below the coupling transition is highly
nonuniform, which facilitates quantum creep. We speculate that in the mixed
state below the coupling transition, where dissipation is nonohmic, the current
distribution may be unstable with respect to self-channeling resulting in the
formation of very thin current-carrying layers.Comment: 11 pages, 9 figures, Submitted to Phys. Rev.
Sensitive limits on the abundance of cold water vapor in the DM Tau protoplanetary disk
We performed a sensitive search for the ground-state emission lines of ortho-
and para-water vapor in the DM Tau protoplanetary disk using the Herschel/HIFI
instrument. No strong lines are detected down to 3sigma levels in 0.5 km/s
channels of 4.2 mK for the 1_{10}--1_{01} line and 12.6 mK for the
1_{11}--0_{00} line. We report a very tentative detection, however, of the
1_{10}--1_{01} line in the Wide Band Spectrometer, with a strength of
T_{mb}=2.7 mK, a width of 5.6 km/s and an integrated intensity of 16.0 mK km/s.
The latter constitutes a 6sigma detection. Regardless of the reality of this
tentative detection, model calculations indicate that our sensitive limits on
the line strengths preclude efficient desorption of water in the UV illuminated
regions of the disk. We hypothesize that more than 95-99% of the water ice is
locked up in coagulated grains that have settled to the midplane.Comment: 5 pages, 3 figures. Accepted for publication in the Herschel HIFI
special issue of A&
Adequacy of therapy for people with both COPD and heart failure in the UK : historical cohort study
Acknowledgments We thank Derek Skinner for his contributions to the data acquisition and handling and Carole Nicholls and Priyanka Raju Konduru for statistical support. Writing and editorial support was provided by Elizabeth V. Hillyer, DVM, supported by Novartis Pharma AG, Basel, Switzerland. Funding This work was supported by Novartis. Employees of the sponsor (listed as authors) participated in the study design, interpretation of the results, writing of the report, and the decision to submit the paper for publication.Peer reviewedPublisher PD
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