Raman anemometry, a method for component-selective velocity measurements of particles in a flow

An anemometer for the measurement of the velocity of particles of different substances in a flow, separate and apart from that of the flow itself, is described. The substances are distinguished by Raman scattering. The velocity is obtained by relating the autocorrelated scattering signal to the known laser beam profile

A Raman anemometer for component-selective velocity measurements of particles in a flow

An anemometer for the measurement of the velocity of particles of different components in a flow, separate and apart from that of the flow itself, is described. As a component-selective mechanism Raman scattering is used. The velocity is measured by relating the autocorrelated scattering signal to the known laser beam profile

Clean and efficient energy conversion processes (CECON-project) : final report

The objectives of the work programme reported are the development and testing of two optimised energy conversion processes, both consisting of a radiant surface gas burner and a ceramic heat exchanger. The first sub-objective of the programme is related to industrial heating, drying and curing processes requiring low and medium heat fluxes. The second sub-objective concerned the development of a compact low cost heat exchanger capable of achieving high levels of heat recovery (up to 60%) which could be easily installed on industrial processes. The objective of the project was the development of a gas powered radiant surface burner with internal recuperation, that has a high efficiency and low emission. This clean and efficient energy conversion process is a combination of two units: a radiant surface gas burner (first sub-objective) and a ceramic heat exchanger (second sub-objective) to preheat the combustion air by the flue gas.

Study of the thermohydraulics of CO2 discharge from a high pressure reservoir

An experimental test set up has been constructed to carry out controlled CO2 release experiments from a high pressure vessel. The test set up is made up of a 500l stainless steel vessel where CO2 can be introduced up to high pressures and where controlled releases can be conducted. The work objective is to get experimental data that help to understand the thermo-hydraulic behavior of CO2 when discharged from a pressurized vessel and to further improve and validate existing and newly developed release and dispersion models. The aim is to get better insight into the fluid behavior in the vessel as well as in the discharged jet, and to understand the relation between the thermodynamic regime inside the high pressure medium and the mass release rate and jet zone characteristics during the release process.In this experimental work, the impact of varying the release orifice diameter and the initial vessel pressure on the CO2 discharge will be examined and analyzed, and the different thermodynamic regimes inside and outside the high pressure medium will be described and interpreted. © 2013 Elsevier Ltd

Diagnostic value of exome and whole genome sequencing in craniosynostosis

BACKGROUND: Craniosynostosis, the premature fusion of one or more cranial sutures, occurs in ∼1 in 2250 births, either in isolation or as part of a syndrome. Mutations in at least 57 genes have been associated with craniosynostosis, but only a minority of these are included in routine laboratory genetic testing. METHODS: We used exome or whole genome sequencing to seek a genetic cause in a cohort of 40 subjects with craniosynostosis, selected by clinical or molecular geneticists as being high-priority cases, and in whom prior clinically driven genetic testing had been negative. RESULTS: We identified likely associated mutations in 15 patients (37.5%), involving 14 different genes. All genes were mutated in single families, except for IL11RA (two families). We classified the other positive diagnoses as follows: commonly mutated craniosynostosis genes with atypical presentation (EFNB1, TWIST1); other core craniosynostosis genes (CDC45, MSX2, ZIC1); genes for which mutations are only rarely associated with craniosynostosis (FBN1, HUWE1, KRAS, STAT3); and known disease genes for which a causal relationship with craniosynostosis is currently unknown (AHDC1, NTRK2). In two further families, likely novel disease genes are currently undergoing functional validation. In 5 of the 15 positive cases, the (previously unanticipated) molecular diagnosis had immediate, actionable consequences for either genetic or medical management (mutations in EFNB1, FBN1, KRAS, NTRK2, STAT3). CONCLUSIONS: This substantial genetic heterogeneity, and the multiple actionable mutations identified, emphasises the benefits of exome/whole genome sequencing to identify causal mutations in craniosynostosis cases for which routine clinical testing has yielded negative results

ოთარ დადიანი

ოთარ დადიანი - მუშნი დადიანის ძმა, 1924 წელს ძმასთან ერთად მონაწილეობდა აჯანყებაშ