360 research outputs found
Trions in a periodic potential
The group-theoretical classification of trion states is presented. It is
based on considerations of products of irreducible representations of the 2D
translation group. For a given BvK period N degeneracy of obtained states is
N^2. Trions consist of two identical particles so the symmetrization of states
with respect to particles transposition is considered. Completely antisymmetric
states can be constructed by introducing antisymmetric spin functions. Two
symmetry adapted bases are considered. The third possibility is postponed for
the further investigations.Comment: revtex, 5 p., sub. to Physica
An extension of Fourier analysis for the n-torus in the magnetic field and its application to spectral analysis of the magnetic Laplacian
We solved the Schr{\"o}dinger equation for a particle in a uniform magnetic
field in the n-dimensional torus. We obtained a complete set of solutions for a
broad class of problems; the torus T^n = R^n / {\Lambda} is defined as a
quotient of the Euclidean space R^n by an arbitrary n-dimensional lattice
{\Lambda}. The lattice is not necessary either cubic or rectangular. The
magnetic field is also arbitrary. However, we restrict ourselves within
potential-free problems; the Schr{\"o}dinger operator is assumed to be the
Laplace operator defined with the covariant derivative. We defined an algebra
that characterizes the symmetry of the Laplacian and named it the magnetic
algebra. We proved that the space of functions on which the Laplacian acts is
an irreducible representation space of the magnetic algebra. In this sense the
magnetic algebra completely characterizes the quantum mechanics in the magnetic
torus. We developed a new method for Fourier analysis for the magnetic torus
and used it to solve the eigenvalue problem of the Laplacian. All the
eigenfunctions are given in explicit forms.Comment: 32 pages, LaTeX, minor corrections are mad
Spin Polaron Effective Magnetic Model for La_{0.5}Ca_{0.5}MnO_3
The conventional paradigm of charge order for La_{1-x}Ca_xMnO_3 for x=0.5 has
been challenged recently by a Zener polaron picture emerging from experiments
and theoretical calculations. The effective low energy Hamiltonian for the
magnetic degrees of freedom has been found to be a cubic Heisenberg model, with
ferromagnetic nearest neighbor and frustrating antiferromagnetic next nearest
neighbor interactions in the planes, and antiferromagnetic interaction between
planes. With linear spin wave theory and diagonalization of small clusters up
to 27 sites we find that the behavior of the model interpolates between the A
and CE-type magnetic structures when a frustrating intraplanar interaction is
tuned. The values of the interactions calculated by ab initio methods indicate
a possible non-bipartite picture of polaron ordering differing from the
conventional one.Comment: 21 pages and 8 figures (included), Late
Neel probability and spin correlations in some nonmagnetic and nondegenerate states of hexanuclear antiferromagnetic ring Fe6: Application of algebraic combinatorics to finite Heisenberg spin systems
The spin correlations \omega^z_r, r=1,2,3, and the probability p_N$ of
finding a system in the Neel state for the antiferromagnetic ring Fe(III)6 (the
so-called `small ferric wheel') are calculated. States with magnetization M=0,
total spin 0<=S<=15 and labeled by two (out of four) one-dimensional
irreducible representations (irreps) of the point symmetry group D_6 are taken
into account. This choice follows from importance of these irreps in analyzing
low-lying states in each S-multiplet. Taking into account the Clebsch--Gordan
coefficients for coupling total spins of sublattices (SA=SB=15/2) the global
Neel probability p*_N can be determined. Dependencies of these quantities on
state energy (per bond and in the units of exchange integral J) and the total
spin S are analyzed. Providing we have determined p_N(S) etc. for other
antiferromagnetic rings (Fe10, for instance) we could try to approximate
results for the largest synthesized ferric wheel Fe18. Since thermodynamic
properties of Fe6 have been investigated recently, in the present
considerations they are not discussed, but only used to verify obtained values
of eigenenergies. Numerical results re calculated with high precision using two
main tools: (i) thorough analysis of symmetry properties including methods of
algebraic combinatorics and (ii) multiple precision arithmetic library GMP. The
system considered yields more than 45 thousands basic states (the so-called
Ising configurations), but application of the method proposed reduces this
problem to 20-dimensional eigenproblem for the ground state (S=0). The largest
eigenproblem has to be solved for S=4; its dimension is 60. These two facts
(high precision and small resultant eigenproblems) confirm efficiency and
usefulness of such an approach, so it is briefly discussed here.Comment: 13 pages, 7 figs, 5 tabs, revtex
New Insights into the Cell Biology of Hematopoietic Progenitors by Studying Prominin-1 (CD133)
Prominin-1 (alias CD133) has received considerable interest because of its expression by several stem and progenitor cells originating from various sources, including the neural and hematopoietic systems. As a cell surface marker, prominin-1 is now used for somatic stem cell isolation. Its expression in cancer stem cells has broadened its clinical value, as it might be useful to outline new prospects for more effective cancer therapies by targeting tumor-initiating cells. Cell biological studies of this molecule have demonstrated that it is specifically concentrated in various membrane structures that protrude from the planar areas of the plasmalemma. Prominin-1 binds to the plasma membrane cholesterol and is associated with a particular membrane microdomain in a cholesterol-dependent manner. Although its physiological function is not yet determined, it is becoming clear that this cell surface protein, as a unique marker of both plasma membrane protrusions and membrane microdomains, might reveal new aspects of the cell biology of rare stem and cancer stem cells. The aim of this review is to outline the recent discoveries regarding the dynamic reorganization of the plasma membrane of rare CD133+ hematopoietic progenitor cells during cell migration and division.Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugÀnglich
Emerging Concepts Impacting Head and Neck Cancer Surgery Morbidity
All treatment modalities for head and neck cancer carry with them a risk of adverse events. Head and neck surgeons are faced with significant challenges to minimize associated morbidity and manage its sequelae. Recognizing situations in which a surgical complication is an adverse event inherent to the procedure can alleviate the psychologic impact a complication might have on the treatment team and minimize external and internal pressures. Focusing on the complications that can be effectively modified, future complications can be avoided. Also, some surgical morbidities may not be preventable, necessitating the option to reconsider whether the incidents should be labeled toxic reactions rather than a complication. This discussion highlights some of the areas in which additional research is needed to achieve the goal of minimizing the impact of surgical morbidity.Peer reviewe
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Understanding misuse of partially automated vehicles â a discussion of NTSBâs findings of the 2018 Mountain View Tesla Crash
This document discusses a fatal crash from March 23, 2018 involving a Tesla Model X using the partially automated 'Autopilot' function. It provides a critique of the NTSB's report and examines the findings from a human factors perspective to contribute towards an enhanced understanding of the circumstances related to this crash. It concludes with areas for open discussion, recommendations for future investigation and five findings of worthwhile of further consideration.
âą We question whether 'driver distraction' is an appropriate classification for a "probable cause" of the crash.
âą We disagree that "familiarization with the vehicle" was not a contributing factor related to this crash.
âą We question the conclusion that driver qualification was not a contributing factor related to this crash.
âą We highlight the need for regulatory bodies to ensure effective driver state monitoring and urge for regulation on minimum requirements for driver state monitoring in partially automated vehicles.
âą We highlight the importance of human-machine interface design in a human-machine shared system and urge for regulation on minimum requirements of such systems within partially automated vehicles.
And in doing so we highlight the importance for a human factors perspective of such events
Magnetic translation groups in an n-dimensional torus
A charged particle in a uniform magnetic field in a two-dimensional torus has
a discrete noncommutative translation symmetry instead of a continuous
commutative translation symmetry. We study topology and symmetry of a particle
in a magnetic field in a torus of arbitrary dimensions. The magnetic
translation group (MTG) is defined as a group of translations that leave the
gauge field invariant. We show that the MTG on an n-dimensional torus is
isomorphic to a central extension of a cyclic group Z_{nu_1} x ... x
Z_{nu_{2l}} x T^m by U(1) with 2l+m=n. We construct and classify irreducible
unitary representations of the MTG on a three-torus and apply the
representation theory to three examples. We shortly describe a representation
theory for a general n-torus. The MTG on an n-torus can be regarded as a
generalization of the so-called noncommutative torus.Comment: 29 pages, LaTeX2e, title changed, re-organized, to be published in
Journal of Mathematical Physic
Diazepam and its metabolites in the mothers' and newborns' hair as a biomarker of prenatal exposure
Pregnant women are exposed to benzodiazepines for therapeutic purposes during gestation. The goal of this study was to evaluate prenatal exposure to benzodiazepines. Time of exposure during course of pregnancy is a significant aspect of fetal exposure to drugs. Benzodiazepine concentration assay in hair of mothers and newborns exposed prenatally to these drugs was performed in the studies. Development, validation and evaluation of benzodiazepine determination method in mothers and their newborns enables assessment of health risks for the child and implementation of adequate therapeutic procedures. We used A LC-ESI-MS/MS method that allowed determination of diazepam (the main benzodiazepine used by pregnant women was diazepam) and its metabolites (nordazepam, oxazepam) in hair of mothers and newborns. LOQ 10 pg/mg of hair was used in the study. Results: concentration of nordazepam was higher than parent drug (diazepam) and higher in newbornsâ hair when compared to mothersâ. The mean concentrations of diazepam in mothersâ hair were 31.6±36.0 and 34.1±42.4 pg/mg in the second and third trimester of pregnancy respectively. The mean concentration of diazepam in newbornsâ hair was higher and reached levels of 53.3±36.5 pg/mg. The mean concentration of nordazepam in the mothersâ hair corresponding to the second and third trimester was 52.9±48.1 and 89.9±122.8 pg/mg, respectively. Nordazepam in the newbornsâ hair was detected at the mean level of 108.1±144.2 pg/mg. It was concluded that diazepam and nordazepam are permanently incorporated into the hair structure. Presence of diazepam and its metabolites in newbornâs hair confirms that these benzodiazepines permeate placental barrier. Segmental analysis of mothersâ hair enabled the assessment of drug administration time. Diazepam and its metabolites determined in hair of newborns may serve as biomarkers of prenatal exposure to these drugs. The performed LC-MS/MS analysis was accurate enough to determine even low concentrations of benzodiazepines, at the level of few pg/mg of hair. Levels of diazepam detected in hair of newborns were higher than levels determined in mothers. This may confirm the fact, that fetusâs ability to metabolize diazepam is scarce. Nordazepam was found in higher concentrations in hair of newborns than in hair of mothers, which may suggest that it is cumulated in childâs organism. Other metabolites of diazepam - oxazepam and temazepam - were detected in very few cases, in low concentrations
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