Counter-conditioning as an intervention to modify anti-fat attitudes

This study examined the effect of anti-fat attitude counter-conditioning using positive images of obese individuals participants completed implicit and explicit measures of attitudes towards fatness on three occasions: no intervention; following exposure to positive images of obese members of the general public; and to images of obese celebrities. Contrary to expectations, positive images of obese individuals did not result in more positive attitudes towards fatness as expected and, in some cases, indices of these attitudes worsened. Results suggest that attitudes towards obesity and fatness may be somewhat robust and resistant to change, possibly suggesting a central and not peripheral processing route for their formation

Spectral and magnetic studies on some metal complexes of sulphur-containing ligands

Imperial Users onl

IGFBP-5 as a biomarker of de-differentiation in hepatocytes

Describes IGFBP-5 as a biomarker of de-differentiation in hepatocytes presented at the 47th Congress of the European-Societies-of-Toxicolog

Factors that influence hypothetical treatment decisions for newborns with mental retardation and an accompanying life-threatening medical disorder

Treatment decisions made on behalf of newborns with mental retardation and an accompanying life-threatening medical disorder were studied. A group of 360 college students answered a set of questionnaires and responded to a vignette which asked for treatment decisions. The options ranged from full treatment including surgery to no treatment at all. The relationship of a number of variables to the treatment choices was assessed. The variables included level of moral reasoning, level of knowledge about and attitudes toward individuals with retardation, prior experience with individuals with retardation, religious affiliation, level of religious belief, prediction of quality of life for the infant, and ethical justification. The majority of participants selected full treatment. Level of retardation, quality of life projection, prior experience, and ethical position were all significantly related to treatment choice. Additionally, changes in treatment choice after additional information was provided were assessed. Quality of life projection and ethical position were also significantly related to changes of treatment. Implications for public policy concerning treatment of newborns, public education concerning people with mental retardation, and counseling provided to parents faced with treatment decisions were discussed

The role of expectations in the FRB/US macroeconomic model

In the past year, the staff of the Board of Governors of the Federal Reserve System began using a new macroeconomic model of the U.S. economy referred to as the FRB/US model. This system of mathematical equations, describing interactions among economic measures such as inflation, interest rates, and gross domestic product, is one of the tools used in economic forecasting and the analysis of macroeconomic policy issues at the Board. The FRB/US model replaces the MPS model, which, with periodic revisions, had been used at the Federal Reserve Board since the early 1970s. A key feature of the new model is that expectations of future economic conditions are explicit in many of its equations. Because of this clear delineation of expectations, the FRB/US model can be used to study issues that would be difficult or impossible to study with the MPS model. For example, the new model can show how the economy's response to specific events, such as a reduction in defense spending, may vary considerably with the speed at which the public recognizes that the event has occurred or will occur.Econometric models ; Federal Reserve System ; Forecasting

Diet-induced obesity impairs mammary development and lactogenesis in murine mammary gland

We have developed a mouse model of diet-induced obesity that shows numerous abnormalities relating to mammary gland function. Animals ate 40% more calories when offered a high-fat diet and gained weight at three times the rate of controls. They exhibited reduced conception rates, increased peripartum pup mortality, and impaired lactogenesis. The impairment of lactogenesis involved lipid accumulation in the secretory epithelial cells indicative of an absence of copius milk secretion. Expression of mRNAs for -casein, whey acid protein, and -lactalbumin were all decreased immediately postpartum but recovered as lactation was established over 2–3 days. Expression of acetyl-CoA carboxylase (ACC)- mRNA was also decreased at parturition as was the total enzyme activity, although there was a compensatory increase in the proportion in the active state. By day 10 of lactation, the proportion of ACC in the active state was also decreased in obese animals, indicative of suppression of de novo fatty acid synthesis resulting from the supply of preformed fatty acids in the diet. Although obese animals consumed more calories in the nonpregnant and early pregnant states, they showed a marked depression in fat intake around day 9 of pregnancy before food intake recovered in later pregnancy. Food intake increased dramatically in both lean and obese animals during lactation although total calories consumed were identical in both groups. Thus, despite access to high-energy diets, the obese animals mobilized even more adipose tissue during lactation than their lean counterparts. Obese animals also exhibited marked abnormalities in alveolar development of the mammary gland, which may partially explain the delay in differentiation evident during lactogenesis

Oxidative stress via hydrogen peroxide and menadione does not induce the secretion of IGFBP-5 in primary rat hepatocytes

Conference abstract describing how oxidative stress via hydrogen peroxide and menadione does not induce the secretion of IGFBP-5 in primary rat hepatocytes. Presented at the 2010 annual congress of the british toxicology societ

Smart technology for healthcare: Exploring the antecedents of adoption intention of healthcare wearable technology

© The Author(s), 2019. Technological advancement and personalized health information has led to an increase in people using and responding to wearable technology in the last decade. These changes are often perceived to be beneficial, providing greater information and insights about health for users, organizations and healthcare and government. However, to date, understanding the antecedents of its adoption is limited. Seeking to address this gap, this cross-sectional study examined what factors influence users’ adoption intention of healthcare wearable technology. We used self-administrated online survey to explore adoption intentions of healthcare wearable devices in 171 adults residing in Hong Kong. We analyzed the data by Partial least squares – structural equation modelling (PLS-SEM). The results reveal that perceived convenience and perceived irreplaceability are key predictors of perceived useful ness, which in turn strengthens users’ adoption intention. Additionally, the results also reveal that health belief is one of the key predictors of adoption intention. This paper contributes to the extant literature by providing understanding of how to strengthen users’ intention to adopt healthcare wearable technology. This includes the strengthening of perceived convenience and perceived irreplaceability to enhance the perceived usefulness, incorporating the extensive communication in the area of healthcare messages, which is useful in strengthening consumers’ adoption intention in healthcare wearable technology

Nominal Income Targeting with the Monetary Base as Instrument: An Evaluation of McCallum\u27s Rule

In this paper, we explore McCallum\u27s monetary base instrument rule in the context of several models. The first section uses two models, previously utilized by McCallum, to demonstrate the general properties of his rule and to update through 1992 the empirical support for the rule. The second section uses models that allow a significant role for interest rates in transmitting the effects of changes in the monetary base to aggregate demand. The analysis in these two sections makes two main points: (1) Shifts. or instabilities, in the structural relationship between the base and nominal GNP in the 1980s and 1990s raise questions about the efficacy of the proposed rule; and (2) The ability of McCallum\u27s base instrument rule to control nominal output depends on the response pattern of the target variable, nominal output, to changes in the base. In the sequence of models presented, we lay out these dynamic linkages in successively more detail and examine their ·implications for nominal income targeting

Combination of ATR Inhibition and X-Ray Irradiation Radiosensitizes Cancer Cells

https://openworks.mdanderson.org/sumexp21/1250/thumbnail.jp