Mapping Local Perspectives in the Historical Archaeology of Vanuatu Mission Landscapes

The concept of place is a powerful theoretical tool in the social sciences and humanities, which can be especially useful in archaeological work that involves community-based collaboration. Using place as a starting point, archaeologists can beneficially use their skills to answer questions that are of relevance to the local communities with which we work while also advancing knowledge about the past. For historical archaeology, this often involves engaging in dialogue across multiple lines of evidence, including material remains from the past, written documents, and local oral traditions. Recent fieldwork on the islands of Erromango and Tanna, Vanuatu, exploring early landscapes relating to Christian conversion uses this kind of approach. A major part of preliminary survey work involves mapping features in the mission sites and surrounding areas. Archaeological cartographic techniques help build a sense of place that provides engaging research for a collaborative environment with local Melanesian communities, while also producing new perspectives on colonialism in the South Pacific. This approach is not limited to the recent past, being applicable to any collaborative, community-based archaeological research that incorporates the use of oral traditions

Speech Given on the Occasion of the Exhibition Colonial & Federal Portraits

The exhibition Colonial and Federal Portraits at Bowdoin College was held at the gallery of Wildenstein and Company, New York City.https://digitalcommons.bowdoin.edu/art-museum-exhibition-catalogs/1071/thumbnail.jp

Preliminary Results of the South Vanuatu Archaeological Survey: Cultural Landscapes, Excavation, and Radiocarbon Dating

South Vanuatu was an important hub of settlement and interaction in the tropical southwestern Pacific. A recent field project, the South Vanuatu Archaeological Survey, has begun carrying out field research, focusing initially on the islands of Futuna, Aniwa, and Tanna. This work builds upon pioneering research carried out in the 1960s, which in these islands has not been followed up until the last five years or so. We present initial findings from survey and test excavations carried out in 2016, including new radiocarbon dates for the region and the discovery of pottery on Tanna. KEYWORDS: Melanesia, Vanuatu, cultural landscapes, archaeological survey, radiocarbon dating.This research is supported by an Australian Research Council Discovery Grant (DP160103578) and Valentin’s travel to Vanuatu by CNRS UMR 7041

Intégration polynésienne au Vanuatu (Mélanésie) : étude de cas sur les rapports entre société préexistante et individus migrants

Certaines sociétés humaines modernes de l’archipel du Vanuatu (Mélanésie) présentent des traits culturels polynésiens et parlent des langues polynésiennes. Ces caractéristiques diffèrent de celles des autres sociétés présentes dans l’archipel qui sont apparentés aux influences mélanésiennes régionales. On suppose que des migrations polynésiennes auraient particulièrement contribué à la formation de ces sociétés « polynésiennes » du Vanuatu lors du dernier millénaire. Pourtant, les études arch..

Archaeology in 2022: Counter‐myths for hopeful futures

Archaeology in 2022 features more calls than ever for a socially and politically engaged, progressive discipline. Archaeologists increasingly respect and integrate decolonizing and Indigenous knowledge in theory and practice. They acknowledge and embrace the fluidity and diversity of sexes and genders, past and present. They document patterns of migration, ancient as well as contemporary, to combat retrograde and racist narratives that remain pervasive in the public sphere. At the same time, the field has a deep‐seated conservative bastion toward which many scholars retreat, arguing for an “objective” past that is free of political implications or interpretive ambiguity. As anarchist archaeologists, we see the myth of the objective past as one of many interconnected myths that have provided the basis for an archaeology that reifies and proliferates the current social order. We deconstruct myths relating to capitalist and colonialist ideologies of “human nature,” the assumed inevitability of the current order, and fatalistic commitment to dystopian or utopian futures. As alternatives, we present counter‐myths that emphasize the contingent and political nature of archaeological praxis, the creative and collaborative foundation of communities, the alternative orders that archaeology uncovers, and the role of a hopeful past for constructing the possibilities of different futures

Preclinical Evaluation of Long-Acting Emtricitabine Semi-Solid Prodrug Nanoparticle Formulations.

Long-acting injectable (LAI) formulations promise to deliver patient benefits by overcoming issues associated with non-adherence. A preclinical assessment of semi-solid prodrug nanoparticle (SSPN) LAI formulations of emtricitabine (FTC) is reported here. Pharmacokinetics over 28 days were assessed in Wistar rats, New Zealand white rabbits, and Balb/C mice following intramuscular injection. Two lead formulations were assessed for the prevention of an HIV infection in NSG-cmah-/- humanised mice to ensure antiviral activities were as anticipated according to the pharmacokinetics. Cmax was reached by 12, 48, and 24 h in rats, rabbits, and mice, respectively. Plasma concentrations were below the limit of detection (2 ng/mL) by 21 days in rats and rabbits, and 28 days in mice. Mice treated with SSPN formulations demonstrated undetectable viral loads (700 copies/mL detection limit), and HIV RNA remained undetectable 28 days post-infection in plasma, spleen, lung, and liver. The in vivo data presented here demonstrate that the combined prodrug/SSPN approach can provide a dramatically extended pharmacokinetic half-life across multiple preclinical species. Species differences in renal clearance of FTC mean that longer exposures are likely to be achievable in humans than in preclinical models

Quantitative Deep Sequencing Reveals Dynamic HIV-1 Escape and Large Population Shifts during CCR5 Antagonist Therapy In Vivo

High-throughput sequencing platforms provide an approach for detecting rare HIV-1 variants and documenting more fully quasispecies diversity. We applied this technology to the V3 loop-coding region of env in samples collected from 4 chronically HIV-infected subjects in whom CCR5 antagonist (vicriviroc [VVC]) therapy failed. Between 25,000–140,000 amplified sequences were obtained per sample. Profound baseline V3 loop sequence heterogeneity existed; predicted CXCR4-using populations were identified in a largely CCR5-using population. The V3 loop forms associated with subsequent virologic failure, either through CXCR4 use or the emergence of high-level VVC resistance, were present as minor variants at 0.8–2.8% of baseline samples. Extreme, rapid shifts in population frequencies toward these forms occurred, and deep sequencing provided a detailed view of the rapid evolutionary impact of VVC selection. Greater V3 diversity was observed post-selection. This previously unreported degree of V3 loop sequence diversity has implications for viral pathogenesis, vaccine design, and the optimal use of HIV-1 CCR5 antagonists

Norms of Presentational Force

This is the author's accepted manuscript, made available with permission of the American Forensic Association.Can style or presentational devices reasonably compel us to believe, agree, act? I submit that they can, and that the normative pragmatic project explains how. After describing a normative pragmatic approach to presentational force, I analyze and evaluate presentational force in Susan B. Anthony's "Is it a Crime for a U. S. Citizen to Vote" as it apparently proceeds from logic, emotion, and style. I conclude with reflections on the compatibility of the normative pragmatic approach with the recently-developed pragma-dialectical treatment of presentational devices

Language continuity despite population replacement in Remote Oceania

Recent genomic analyses show that the earliest peoples reaching Remote Oceania—associated with Austronesian-speaking Lapita culture—were almost completely East Asian, without detectable Papuan ancestry. However, Papuan-related genetic ancestry is found across present-day Pacific populations, indicating that peoples from Near Oceania have played a significant, but largely unknown, ancestral role. Here, new genome-wide data from 19 ancient South Pacific individuals provide direct evidence of a so-far undescribed Papuan expansion into Remote Oceania starting ~2,500 yr BP, far earlier than previously estimated and supporting a model from historical linguistics. New genome-wide data from 27 contemporary ni-Vanuatu demonstrate a subsequent and almost complete replacement of Lapita-Austronesian by Near Oceanian ancestry. Despite this massive demographic change, incoming Papuan languages did not replace Austronesian languages. Population replacement with language continuity is extremely rare—if not unprecedented—in human history. Our analyses show that rather than one large-scale event, the process was incremental and complex, with repeated migrations and sex-biased admixture with peoples from the Bismarck Archipelago