Fibroblastic Interactions with High-Porosity Ti-6Al-4V Metal Foam

Peer reviewed: YesNRC publication: Ye

Apatite Glass-Ceramics: A Review

The authors would like to thank Cera Dynamics Limited, part of the James Kent Group and the Institute of Dentistry (Queen Mary University of London) for jointly funding TD

Comprehensive Study of the Chelation and Coacervation of Alkaline Earth Metals in the Presence of Sodium Polyphosphate Solution

The effect of chelation of three alkaline earth metals (Ca, Sr, and Ba) by polyphosphates on the pH and viscosity of the solution is examined and correlated to the phosphate glass properties. Also, the impact of the polyphosphate average degree of polymerization (<i>D</i>_p) as well as the type and amount of chelated divalent cation on the degradation rate of the chains is studied. Subsequently, the number of divalent cations required for polyphosphate chain agglomeration to form a coacervate, and the resulting composition of these coacervates, was investigated. A decrease in polyphosphate solution pH during chelation was routinely obtained, with a sudden shift in the rate of pH drop occurring around a divalent cation/phosphorus molar ratio of 0.18. Longer chains or cations with a smaller ionic radius accelerated the rate of <i>D</i>_p reduction. The number of divalent cations required for coacervation depends on different variables such as the polyphosphate concentration, the <i>D</i>_p, and the type of divalent cation. The formed coacervate retains the <i>D</i>_p of polyphosphate originally used for coacervation, and the resulting Ca/P molar ratio depends largely on the amount of calcium being used during coacervation. Overall, this article helps one to understand the coacervation of polyphosphates in order to exploit their potential as a biomaterial

Measurement of fluid ingress into calcium polyphosphate bioceramics using nuclear magnetic resonance microscopy

NRC publication: Ye