120 research outputs found

    Chapter The offshore environmental impact by Sarno river in Naples bay (South-West Italy)

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    The goal of this work has been to establish the influence of the Sarno river on the present sedimentation in the Naples bay continental shelf by evaluating organic matter contribution and pollution. Sediments samples were collected, by van Veen grab, in 71 stations located offshore the Sarno river between Vesuvian and Sorrento Peninsula coasts. The characteristics of the surface sediments were analysed to highlight spatial trends in the (i) granulometry (grain-size); (ii) total nitrogen, organic carbon and total phosphorus; (iii) metal content (Hg, Cd, Pb, As, Cr, Cu, Ni, Zn, Fe and Mn)

    Prospezioni sismiche, geoelettriche ed elettromagnetiche ad alta risoluzione in prossimità della foce del Fiume Volturno

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    Nell’ambito dell’Obiettivo Realizzativo 2.3 “Sviluppo e allestimento di sensoristica e sistemi innovativi per osservazioni dell’iterazione terra-aria per la qualità dell’aria e degli ecosistemi agro-forestali” del progetto PON I-AMICA (Infrastruttura di Alta tecnologia per il Monitoraggio Integrato Climatico-Ambientale), l’Istituto per l’Ambiente Marino Costiero del Consiglio Nazionale delle Ricerche (CNR-I.A.M.C.) di Napoli, coordinato dal dott. Vincenzo Di Fiore, ha eseguito delle prospezioni sismiche, geoelettriche ed elettromagnetiche in un’area prospiciente la foce del Fiume Volturno. Tali indagini hanno avuto come obiettivo: La valutazione dell’intrusione nelle falde acquifere di componenti idrosaline provenienti dalla vicina area costiera; Lo studio, con risoluzione metrica, della porzione superficiale (0 - 80 metri di profondità) del sottosuolo al fine di caratterizzare, in termini di spessori e di velocità di propagazione, le serie riflettive che caratterizzano l’area in esame

    Multivariate tools to investigate the spatial contaminant distribution in a highly anthropized area (Gulf of Naples, Italy)

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    The Gulf of Naples located in a high anthropized coastal area is subjected to an infrastructural intervention for the installation of a submarine power pipeline. In order to evaluate the distribution of contaminants in the seafloor sediments, a preliminary study has been conducted in the area using multivariate techniques. The statistic approach was performed to gain insights on the occurrence of organic and inorganic contaminants within the area, aiming to identify the relevant hot spots. Three geographical sub-areas influenced by different contaminant association were recognized: Torre Annunziata (TA), Capri (CA), and middle offshore (MO). TA and CA resulted marked by a severe contamination pattern due to anthropogenic pressures. In addition, the influence of the depositional basin in governing the contamination trend has been pointed out. The supervised technique PLS_DA resulted to be a powerful tool in addressing the complexity of the huge dataset acquired during the marine survey, highlighting the main trends in the variability of quality indicators, orienting thus the deeper investigations during follow-up monitoring activities

    Polymeric nano-micelles as novel cargo-carriers for LY2157299 liver cancer cells delivery

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    LY2157299 (LY), which is very small molecule bringing high cancer diffusion, is a pathway antagonist against TGF\u3b2. LY dosage can be diluted by blood plasma, can be captured by immune system or it might be dissolved during digestion in gastrointestinal tract. The aim of our study is to optimize a "nano-elastic" carrier to avoid acidic pH of gastrointestinal tract, colon alkaline pH, and anti-immune recognition. Polygalacturonic acid (PgA) is not degradable in the gastrointestinal tract due to its insolubility at acidic pH. To avoid PgA solubility in the colon, we have designed its conjugation with Polyacrylic acid (PAA). PgA-PAA conjugation has enhanced their potential use for oral and injected dosage. Following these pre-requisites, novel polymeric nano-micelles derived from PgA-PAA conjugation and loading LY2157299 are developed and characterized. Efficacy, uptake and targeting against a hepatocellular carcinoma cell line (HLF) have also been demonstrated.LY2157299 (LY), which is very small molecule bringing high cancer diffusion, is a pathway antagonist against TGF\uce\ub2. LY dosage can be diluted by blood plasma, can be captured by immune system or it might be dissolved during digestion in gastrointestinal tract. The aim of our study is to optimize a \ue2\u80\u9cnano-elastic\ue2\u80\u9d carrier to avoid acidic pH of gastrointestinal tract, colon alkaline pH, and anti-immune recognition. Polygalacturonic acid (PgA) is not degradable in the gastrointestinal tract due to its insolubility at acidic pH. To avoid PgA solubility in the colon, we have designed its conjugation with Polyacrylic acid (PAA). PgA-PAA conjugation has enhanced their potential use for oral and injected dosage. Following these pre-requisites, novel polymeric nano-micelles derived from PgA-PAA conjugation and loading LY2157299 are developed and characterized. Efficacy, uptake and targeting against a hepatocellular carcinoma cell line (HLF) have also been demonstrated

    Hide and seek between Andromeda's halo, disk, and giant stream

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    Photometry in B, V (down to V ~ 26 mag) is presented for two 23' x 23' fields of the Andromeda galaxy (M31) that were observed with the blue channel camera of the Large Binocular Telescope during the Science Demonstration Time. Each field covers an area of about 5.1kpc x 5.1kpc at the distance of M31 ((m-M)o ~ 24.4 mag), sampling, respectively, a northeast region close to the M31 giant stream (field S2), and an eastern portion of the halo in the direction of the galaxy minor axis (field H1). The stream field spans a region that includes Andromeda's disk and the giant stream, and this is reflected in the complexity of the color magnitude diagram of the field. One corner of the halo field also includes a portion of the giant stream. Even though these demonstration time data were obtained under non-optimal observing conditions the B photometry, acquired in time-series mode, allowed us to identify 274 variable stars (among which 96 are bona fide and 31 are candidate RR Lyrae stars, 71 are Cepheids, and 16 are binary systems) by applying the image subtraction technique to selected portions of the observed fields. Differential flux light curves were obtained for the vast majority of these variables. Our sample includes mainly pulsating stars which populate the instability strip from the Classical Cepheids down to the RR Lyrae stars, thus tracing the different stellar generations in these regions of M31 down to the horizontal branch of the oldest (t ~ 10 Gyr) component.Comment: 59 pages, 26 figures, 12 tables, ApJ in pres

    DESAFIOS E OPORTUNIDADES DO BUDISMO NO BRASIL: RELATO DE UM SIMPÓSIO COM TRADUTORES/ACADÊMICOS BUDISTAS

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    A partir de um Simpósio Virtual ocorrido em agosto de 2020 com praticantes e estudiosos do budismo, alguns deles tradutores budistas de diversas línguas (chinês, japonês, tibetano e sânscrito) para o português, emergem várias questões. A motivação deste encontro foi a de dialogar sobre importantes questões sobre o budismo no presente momento atual, suas oportunidades e desafios. Ao longo do debate fica evidente o grande hiato cultural entre o Brasil e os países asiáticos. Igualmente se revela a sofisticação e rigor necessários às traduções bem como a necessidade e a dificuldade de estabelecer esse debate na academia. Este artigo apresenta os pontos mais importantes de cada exposição, os coloca em perspectiva e encaminha considerações finais sobre os desafios e oportunidades presentes no amplo tema das traduções e do diálogo acadêmico com o budismo

    Funcionários públicos e contratação administrativa. Comentários sobre o acórdão do Tribunal do Contencioso Administrativo n.º 383/2018.

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    This article deals with the analysis of judgment No. 383/2018 ruled by the Court for Administrative Matters, on September 20th, 2018, which confirms the administrative act issued by the National Administration of Power Plants and Electric Transmissions. Said ruling applied a disciplinary sanction to three officials due to the detection of irregularities in their participation in an administrative contracting procedure. The article analyzes the breach of the principles applicable in such procedures, as well as the usual check-ups to which public officials are subject.El presente artículo aborda el análisis de la sentencia del Tribunal de lo Contencioso Administrativo No. 383/2018 de 20 de setiembre de 2018 que confirma el acto administrativo dictado por la Administración Nacional de Usinas y Transmisiones Eléctricas, que aplica una sanción disciplinaria a tres funcionarios en atención a la constatación de irregularidades en su participación en un procedimiento de contratación administrativa. El trabajo analiza la vulneración a los principios aplicables en dichos procedimientos, así como a los controles a que están sujetos los funcionarios públicos.Este artigo analisa o acórdão do Tribunal de Contencioso Administrativo No. 383/2018 de 20 de setembro de 2018, que confirma o ato administrativo emitido pela Administração Nacional de Centrais Eléctricas e Transmissões, que aplica uma sanção disciplinar a três funcionários públicos em resposta à constatação de irregularidades na sua participação num processo de concurso administrativo. O documento analisa a violação dos princípios aplicáveis a tais procedimentos, bem como os controles a que estão sujeitos os funcionários públicos

    Challenges and opportunities of buddhism in Brazil : report of a symposium with buddhist translators/academics

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    A partir de um Simpósio Virtual ocorrido em agosto de 2020 com praticantes e estudiosos do budismo, alguns deles tradutores budistas de diversas línguas (chinês, japonês, tibetano e sânscrito) para o português, emergem várias questões. A motivação deste encontro foi a de dialogar sobre importantes questões sobre o budismo no presente momento que vivemos, suas oportunidades e desafios. Ao longo do debate fica evidente o grande hiato cultural entre o Brasil e os países asiáticos. Igualmente se revela a sofisticação e rigor necessários às traduções bem como a necessidade e a dificuldade de estabelecer esse debate na academia. Este artigo apresenta os pontos mais importantes de cada exposição, os coloca em perspectiva e encaminha considerações finais sobre os desafios e oportunidades presentes no amplo tema das traduções e do diálogo acadêmico com o budismo.Several questions emerged from a Virtual Symposium that took place in August 2020 with practitioners and scholars of Buddhism, some of them Buddhist translators from different languages (Chinese, Japanese, Tibetan and Sanskrit) into Portuguese. The motivation of this meeting was to discuss important questions about Buddhism in our day and age, its opportunities and challenges. Throughout the debate it became evident that there is a great cultural gap between Brazil and Asian countries. It also reveals the sophistication and rigor required for translations, as well as the need and difficulty of establishing this debate in academia. This article presents the most important points of each speech, puts them in perspective and makes final considerations about the challenges and opportunities present in the broad topic of translations and academic dialogue with Buddhism
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