Review of Body Mass Index Reduction Interventions among Mexican Origin Latinos and Latinas

Objectives: A literature review was conducted to identify factors associated with successful Body Mass Index (BMI) reduction interventions for Mexican origin US Hispanic/Latino populations. Data Source: An academic database search was conducted of peer-reviewed literature primarily in public health, medical anthropology, medical sociology, and biomedical databases. The key search words used were “Latino or Hispanic or Mexican”, in combination with “intervention”, “obesity”, “body mass index”, “weight reduction”, “best practices” and “lessons learned”. Inclusion Criteria: The inclusion criteria included an intervention protocol, with BMI measures, and a majority of participants identified as Mexican origin Hispanics. Search results yielded a total of 118 articles with 19 studies meeting the inclusion criteria. Results: The review found that education and the use of culturally tailored/sensitive materials are important factors in BMI reduction. In addition, the study found that family centered and community based approaches are some of the most successful evidence based practices found in the Latino health literature. Conclusions: Obesity and its sequelae disproportionately impact both US and non-US Latino/ Hispanic communities and have life-long and intergenerational consequences. The findings from this review may serve as a guide to the development of more successful interventions and best practices to address the needs of Mexican origin Latino populations

Contextualizing the Relationship between Culture and Puerto Rican Health: Towards a Place-Based Framework of Minority Health Disparities

In both the culture of poverty literature and the acculturation literature, Puerto Ricans are portrayed in negative terms. The culture of poverty framework attributes Puerto Rican poverty to the mental, behavioral, and moral pathology of Puerto Rican individuals and to Puerto Rican culture. Similarly, outdated acculturation frameworks also trace the poor health of immigrants and racialized minorities, such as Puerto Ricans, to equivalent perceived deficiencies. In this paper, we argue that both the culture of poverty and acculturation frameworks are two pillars of the White Racial Frame (Feagin 2009) that sustains racial inequality in the United States. To build our case, we provide an overview of Puerto Rican physical health disparities and highlight key findings. Then, we analyze this literature using natural language processing (NLP) tools to examine the lexicon of words that scholars use to understand such disparities. Our literature review shows that Puerto Ricans are generally doing worse than other groups across a range of health indicators. Results from the NLP analyses reveal that the lexicon of the culture of poverty and outdated notions of acculturation are rhetorical tools that scholars still use to make sense of these conditions. We conclude by arguing that moving away from a White Racial Frame of Puerto Rican health requires a theoretical model that puts race, place, and culture within a multilevel framework that we call the Racialized Place Inequality Framework

Life Expectancies With Depression by Age of Migration and Gender Among Older Mexican Americans

Background and Objectives: Prior studies examining depression among older Mexican Americans suggest both women and immigrants are at higher risk of depressive symptomatology than males and U.S.-born Mexican Americans. We use data from the Hispanic Established Populations for the Epidemiologic Study of the Elderly to examine whether life expectancy with depression and without depression varies by nativity, age of migration, and gender. Research Design and Methods: Sullivan-based life tables were used to estimate depression life expectancies among Mexican Americans aged 65 years and older residing in the Southwestern United States. Depression is based on the 20-item Center for Epidemiological Studies Depression scale (CES-D). The CES-D is a continuous scale (0–60) with higher values indicating worse mental health. We dichotomize depression as a score of 16 or greater. Results: Immigrant women, particularly those who migrated in late-life (after age 50) are at a significant disadvantage in the number of years after age 65 lived with depression and the ratio of years spent without depression relative to U.S.-born women. Among men, only late-life immigrants were disadvantaged in the number of years spent with depression. Early- and mid-life immigrant males did not differ from U.S.-born males. Discussion and Implications: Our results highlight the heterogeneity among older Mexican Americans in life expectancies with depression. These findings illustrate the importance of considering age of migration as a high-risk factor for depression among Mexican-origin immigrants. Including this risk factor as a part of depression screening is a key step for timely interventions in preventing disability and comorbidities associated with untreated depression

Life Expectancies With Depression by Age of Migration and Gender Among Older Mexican Americans

Background and Objectives: Prior studies examining depression among older Mexican Americans suggest both women and immigrants are at higher risk of depressive symptomatology than males and U.S.-born Mexican Americans. We use data from the Hispanic Established Populations for the Epidemiologic Study of the Elderly to examine whether life expectancy with depression and without depression varies by nativity, age of migration, and gender. Research Design and Methods: Sullivan-based life tables were used to estimate depression life expectancies among Mexican Americans aged 65 years and older residing in the Southwestern United States. Depression is based on the 20-item Center for Epidemiological Studies Depression scale (CES-D). The CES-D is a continuous scale (0–60) with higher values indicating worse mental health. We dichotomize depression as a score of 16 or greater. Results: Immigrant women, particularly those who migrated in late-life (after age 50) are at a significant disadvantage in the number of years after age 65 lived with depression and the ratio of years spent without depression relative to U.S.-born women. Among men, only late-life immigrants were disadvantaged in the number of years spent with depression. Early- and mid-life immigrant males did not differ from U.S.-born males. Discussion and Implications: Our results highlight the heterogeneity among older Mexican Americans in life expectancies with depression. These findings illustrate the importance of considering age of migration as a high-risk factor for depression among Mexican-origin immigrants. Including this risk factor as a part of depression screening is a key step for timely interventions in preventing disability and comorbidities associated with untreated depression

La enseñanza del Derecho del Trabajo a través del método jurídico: análisis normativo, judicial y doctrinal

La presente memoria tiene por objeto exponer las principales conclusiones a las que se ha llegado en relación con la materia de análisis concerniente a los instrumentos docentes que resultan más adecuados en orden a alcanzar con éxito los objetivos relativos a la enseñanza por competencias y el aprendizaje autónomo que permitan al alumno afrontar con éxito el ejercicio de las profesiones para las que le capacita su titulación. El análisis se lleva a cabo en relación con la asignatura Derecho del Trabajo, que constituye una materia central en el Área de Conocimiento del Derecho del Trabajo y de la Seguridad Social, impartida en varias titulaciones universitarias, principalmente, en los estudios de Derecho, DADE, Relaciones Laborales y Recursos Humanos, pero también en los Grados de Turismo, Criminología o Trabajo Social. En este contexto, y partiendo de la base de la importancia y necesidad de diseñar un tipo de formación (y evaluación) por competencias, el equipo investigador de esta red ha trazado el diseño de dicha asignatura a través del recurso a tres herramientas básicas del método jurídico: el análisis de las normas jurídicas, la interpretación judicial de las mismas, y la exégesis efectuada por parte de la doctrina científica

Platinum-Based Nanoformulations for Glioblastoma Treatment : The Resurgence of Platinum Drugs?

Current therapies for treating Glioblastoma (GB), and brain tumours in general, are inefficient and represent numerous challenges. In addition to surgical resection, chemotherapy and radiotherapy are presently used as standards of care. However, treated patients still face a dismal prognosis with a median survival below 15-18 months. Temozolomide (TMZ) is the main chemotherapeutic agent administered; however, intrinsic or acquired resistance to TMZ contributes to the limited efficacy of this drug. To circumvent the current drawbacks in GB treatment, a large number of classical and non-classical platinum complexes have been prepared and tested for anticancer activity, especially platinum (IV)-based prodrugs. Platinum complexes, used as alkylating agents in the anticancer chemotherapy of some malignancies, are though often associated with severe systemic toxicity (i.e., neurotoxicity), especially after long-term treatments. The objective of the current developments is to produce novel nanoformulations with improved lipophilicity and passive diffusion, promoting intracellular accumulation, while reducing toxicity and optimizing the concomitant treatment of chemo-/radiotherapy. Moreover, the blood-brain barrier (BBB) prevents the access of the drugs to the brain and accumulation in tumour cells, so it represents a key challenge for GB management. The development of novel nanomedicines with the ability to (i) encapsulate Pt-based drugs and pro-drugs, (ii) cross the BBB, and (iii) specifically target cancer cells represents a promising approach to increase the therapeutic effect of the anticancer drugs and reduce undesired side effects. In this review, a critical discussion is presented concerning different families of nanoparticles able to encapsulate platinum anticancer drugs and their application for GB treatment, emphasizing their potential for increasing the effectiveness of platinum-based drugs

Screening the Presence of Non-Typhoidal Salmonella in Different Animal Systems and the Assessment of Antimicrobial Resistance.

Salmonella is a major bacterial foodborne pathogen that causes the majority of worldwide food-related outbreaks and hospitalizations. Salmonellosis outbreaks can be caused by multidrug-resistant (MDR) strains, emphasizing the importance of maintaining public health and safer food production. Nevertheless, the drivers of MDR Salmonella serovars have remained poorly understood. In this study, we compare the resistance profiles of Salmonella strains isolated from 4047 samples from domestic and wild animals in Chile. A total of 106 Salmonella strains (2.61%) are isolated, and their serogroups are characterized and tested for susceptibility to 16 different antimicrobials. The association between antimicrobial resistance (AMR) and a subset of independent variables is evaluated using multivariate logistic models. Our results show that 47 antimicrobial-resistant strains were found (44.3% of the total strains). Of the 47, 28 correspond to single-drug resistance (SDR = 26.4%) and 19 are MDR (17.9%). S. Enteritidis is highly persistent in animal production systems; however, we report that serogroup D strains are 18 times less likely to be resistant to at least one antimicrobial agent than the most common serogroup (serogroup B). The antimicrobials presenting the greatest contributions to AMR are ampicillin, streptomycin and tetracycline. Additionally, equines and industrial swine are more likely to acquire Salmonella strains with AMR. This study reports antimicrobial-susceptible and resistant Salmonella in Chile by expanding the extant literature on the potential variables affecting antimicrobial-resistant Salmonella

Assessment of Hyperbolic Heat Transfer Equation in Theoretical Modeling for Radiofrequency Heating Techniques

Theoretical modeling is a technique widely used to study the electrical-thermal performance of different surgical procedures based on tissue heating by use of radiofrequency (RF) currents. Most models employ a parabolic heat transfer equation (PHTE) based on Fourier’s theory, which assumes an infinite propagation speed of thermal energy. We recently proposed a one-dimensional model in which the electrical-thermal coupled problem was analytically solved by using a hyperbolic heat transfer equation (HHTE), i.e. by considering a non zero thermal relaxation time. In this study, we particularized this solution to three typical examples of RF heating of biological tissues: heating of the cornea for refractive surgery, cardiac ablation for eliminating arrhythmias, and hepatic ablation for destroying tumors. A comparison was made of the PHTE and HHTE solutions. The differences between their temperature profiles were found to be higher for lower times and shorter distances from the electrode surface. Our results therefore suggest that HHTE should be considered for RF heating of the cornea (which requires very small electrodes and a heating time of 0.6 s), and for rapid ablations in cardiac tissue (less than 30 s)

Biodiversity and benthic megafaunal communities inhabiting the Formigas Bank (NE Azores)

The Formigas Bank is an offshore seamount located in the easternmost part of the Azores archipelago (northeast Atlantic). It rises from abyssal depths to the surface, including a small set of islets. The bank holds multiple nature conservation designations, including a Natura 2000 Special Area of Conservation, an OSPAR Marine Protected Area, a RAMSAR site and a Nature Reserve declared under the Azores network of protected areas. The protection is based on the presence of sublittoral biotopes of high conservation interest, and importance as feeding grounds, spawning and nursery areas for many marine species, including fish, cetaceans and turtles. Although some information exists on the sublittoral communities occurring on the seamount summit (e.g., infralittoral Cystoseira and Laminaria beds, circalittoral hydrarian and sponge gardens, rich pelagic fauna), virtually no information was available on the deep-sea communities inhabiting the seamount flanks. Therefore, during the MEDWAVES cruise, the flanks of the Formigas bank have been surveyed using multibeam sonar, an ROV and oceanographic profiles, with the objective to characterise deep-sea biodiversity and megafaunal communities as well as the environment where they occur. This communication will present results from the video annotations of the ten dives made on the seamount slopes between ~500m and ~1,500 m depth. Diverse communities of sedentary suspension-feeding organisms were observed, with more than 20 cold-water coral species (mainly octocorals) being recorded, as well as many different sponge morphotypes. Dense coral garden habitats and sponge grounds were identified on several occasions, confirming the presence of vulnerable marine ecosystems (VMEs) and of ecologically or biologically significant areas (EBSAs). Differences in the abundance and composition of these habitats between the northern and southern dive transects are interpreted as reflecting substrate and geomorphological differences, as well as the potential influence of the Mediterranean Outflow Water (MOW). The new knowledge on deep-sea megafaunal communities reinforces the importance of this seamount as an area of high conservation interest

Nanostructured tungsten as a first wall material for the future nuclear fusion reactors

The lack of materials able to withstand the severe radiation conditions (high thermal loads and atomistic damage) expected in fusion reactors is the actual bottle neck for fusion to become a reality. The main requisite for plasma facing materials (PFM) is to have excellent structural stability since severe cracking or mass loss would hamper their protection role which turns out to be unacceptable. Additional practical requirements for plasma facing materials are among others: (i) high thermal shock resistance, (ii) high thermal conductivity (iii) high melting point (iv) low physical and chemical sputtering, and (v) low tritium retention