Short-Term Evaluation in Growing Rats of Diet Containing Bacillus thuringiensis Cry1Ia12 Entomotoxin: Nutritional Responses and Some Safety Aspects

The Cry1Ia12 entomotoxin from a Brazilian Bacillus thuringiensis strain is currently being expressed in cotton cultivars to confer resistance to insect-pests. The present study aimed to assess the effects of a diet containing Cry1Ia12 protein on growing rats. A test diet containing egg white and Cry1Ia12 (0.1% of total protein) as a protein source was offered to rats for ten days. In addition, an acute toxicity bioassay was performed in rats with a single oral dose of the entomotoxin (12 mg/animal). No adverse effects were observed in the animals receiving the test diet when compared to those receiving a control diet (egg white). The analysed parameters included relative dry weight of internal organs, duodenum histology, blood biochemistry, and nutritional parameters. The results of the acute toxicity test showed no mortality or behaviour alteration. Thus, Cry1Ia12 toxin at the tested concentration does not cause deleterious effects on growing rats when incorporated in the diet for 10 days

Nursing care for children with gastrostomy: integrative review

Objective: To analyze national and international scientific production on nursing care for children with gastrostomy. Method: Integrative review conducted in the databases Latin American and Caribbean Health Sciences (LILACS), Scientific Electronic Library Online (SCIELO),Medical Literature Analysis and Retrieval System Online (MEDLINE) and Cumulative Index to Nursing and Allied Health Literature (CINAHL) without temporal delimitation of publications. The following Health Sciences Descriptors (DeCS) and Medical Subject Headings (MeSH) were used: gastrostomia/gastrostomy/cuidado da criança/children care/enfermagem/nursing. Twenty references were found in LILACS, four in SciELO, 116 in MEDLINE and 167 in CINAHL. The studies found in the LILACS and SciELO did not meet the inclusion criteria. Three articles were selected from MEDLINE and 02 from CINAHL; thus, 05 articles composed the sample of the study. Results: We observed that gastrostomy brought about satisfaction to caregivers despite post-surgery complications. Improvements brought about by the use of the device and reduction of complications related to feeding difficulties, weight gain, decreased vomiting, abdominal distention and fatigue of the patient throughout the day were mentioned. It was also noted that caregivers in the studies felt fear and insecurity at decision-making on the insertion of gastrostomy, showing that the information for the care of these patients was a common concern among them. Conclusion: The study allows us to conclude that the care provided by nurses to children with gastrostomy and family contributes to increase knowledge, thus facilitating decision-making during the management of the device. The use of educational technologies are to be highlighted as a strategy for promoting care during hospitalization and preparing parents to take care of the gastrostomy after hospital discharge. &nbsp

Representações de puérperas sobre o cuidado recebido no trabalho de parto e parto

Objetivo: descrever as representações sociais de puérperas sobre o cuidado recebido durante o trabalho de parto e parto.Metodologia: trata-se de um estudo descritivo baseado na Teoria do Núcleo Central, desenvolvido com 119 puérperas em uma maternidade pública localizada no Brasil, na cidade de Fortaleza, Ceará. Os dados foram coletados por meio do Teste de Associação Livre de Palavras, que continha como estímulos indutores: trabalho de parto, parto, cuidado no trabalho de parto e parto, sendo transcritos e analisados pelo software Evoc.Resultados: a partir da análise estrutural, os vocábulos dor, felicidade e orientação apresentaram maior frequência como elemento central dos respectivos termos indutores.Conclusão: por meio dos resultados obtidos, é possível afirmar que o momento do trabalho de parto e do parto é crucial para que o enfermeiro planeje e execute uma adequada assistência durante o processo de parturição a fim de reduzir o impacto das representações negativas em relação a esse processo.Objective: to describe the social representations puerperal women have about the care they received during labor and delivery.Methodology: this is a descriptive study, based on the Theory of the Central Nucleus, which was undertaken with 119 women in the postpartum period in a public maternity hospital, located in the city of Fortaleza, Ceará, Brazil. The data were collected through the Free Word Association Test, which included as inductive stimuli: care, labor, delivery and care in labor and delivery. The data were transcribed and analyzed with Evoc software.Results: the structural analysis showed that the words “pain”, “happiness” and “guidance” ocurred more frequency as a central feature of the respective inducing terms.Conclusion: the results confirm that the moment of labor and delivery is crucial for nurses in the planning and implementation of adequate care during parturition insofar, as such measures lessen the impact of negative representations of childbirth.Objetivo: describir las representaciones sociales de puérperas sobre el cuidado recibido durante el trabajo de parto y parto.Metodología: se trata de un estudio descriptivo basado en la Teoría del Núcleo Central, desarrollado con 119 madres, en un hospital público de Fortaleza, Ceará, Brasil. Los datos fueron recolectados por medio del Test de Asociación de Palabras, que contenía como estímulos inductores: cuidado, trabajo de parto, parto, cuidado en el trabajo de parto y en el parto, siendo transcritos y analizados por el software Evoc.Resultados: a partir del análisis estructural, los vocablos dolor, felicidad y orientación presentaron mayor frecuencia como elemento central de los respectivos términos inductores.Conclusión: por medio de los resultados obtenidos, es posible afirmar que el momento del trabajo de parto y el parto es crucial para que el enfermero planee y ejecute una adecuada asistencia durante el proceso de parto con el fin de reducir el impacto de las representaciones negativas en relación con ese proceso

Síndrome de Allgrove e amiotrofia: uma associação rara

A Síndrome de Allgrove é uma doença rara hereditária, causada por mutações no gene AAAS, que possui uma tríade clássica de sintomas caracterizada por alacrimia, acalasia e insuficiência adrenal. Além da tríade, sinais neurológicos como disfunção autonômica, microcefalia, disfunção cognitiva ou demência leve, doença do neurônio motor/amiotrofia e outros podem ser mencionados em até 70% dos casos. Nessa perspectiva, o objetivo desse trabalho é a realização de um estudo observacional e exploratório sobre os artigos publicados nos últimos 5 anos sobre associação rara entre a síndrome de allgrove e amiotrofia, uma vez que essa é uma comorbidade rara da síndrome. Dos 140 resultados obtidos na pesquisa, apenas 9 abordaram de forma objetiva sobre o tema, sendo utilizados na confecção do estudo. Segundo a literatura, a amiotrofia é uma comorbidade rara da síndrome de Allgrove, que possui grande relevância devido ao seu curso rápido e progressivo

Inclusão escolar de alunos portadores de Transtorno do Espectro Autista na educação infantil: uma revisão sistemática: School inclusion of students with Autistic Spectrum Disorder in early childhood education: a systematic review

Este artigo debate o problema da inclusão escolar de crianças com transtorno do espectro autista (TEA). Para estabelecer o debate, foi feito um levantamento bibliográfico e referencial para uma revisão sistemática do tema. O objetivo é clarificar os conceitos de inclusão escolar e TEA para debater como é feito o processo educacional de crianças com TEA. Sendo assim, a partir da pesquisa científica de descritores como “inclusão escolar”, “transtorno do espectro autista”, foi observado, pelos diversos autores trabalhados, que ainda há muito o que se debater e trabalhar para que ocorra a inclusão escolar de crianças com TEA. Apesar das muitas tentativas, erros e acertos, o tema ainda é pouco trabalhado e divulgado, visto que há poucos profissionais capacitados na área

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

Care during labor and birth: mothers’ perception

Objective: to describe the care provided to women during labor and delivery in their perception. Methods: study with qualitative approach, developed in a hospital in the northern region of the state of Ceará, with 14 mothers. The analysis explored the content in the light of good care practices during labor and birth, recommended by the National Humanization Policy. Results: the mothers’ speeches revealed the need to make the environment more welcoming and the care more humanized during childbirth, contemplating listening to their problems and their concerns; satisfaction with the use of non-pharmacological methods used for pain relief and with the care given during labor. Conclusion: it was revealed how much human involvement and the search for a qualified assistance to mothers in maternity wards have contributed significantly to the quality of these actions