Degradación de la magnitud de la fuerza de los elásticos de látex según el tiempo de uso empleado en ortodoncia : estudio in vitro

Objetivo: Determinar diferencias entre la degradación de la magnitud de las fuerzas de los elásticos de látex de ortodoncia y el tiempo de uso empleado. Materiales y métodos: En el estudio in vitro se evaluaron 60 elásticos de látex de tres tipos (1/4 4oz, 4/16 6oz y 1/6 4oz) de la marca GAC; fueron estirados tres veces en su diámetro interno y sumergidos en un medio húmedo a 37°C. Las magnitudes de la fuerzas fueron evaluados en intervalos de 5, 11 y 23 horas haciendo uso de un dinamómetro (Gauge Correx®, 250g, Suiza). Mediante la prueba de ANOVA se determinó la significancia estadística. Resultados: Existe diferencias estadísticamente significativa (p<0.001) en los tres tipos de elásticos. La degradación de la magnitud de la fuerza después de 5 horas fue de 20%, 17% y 15,6%; y de 23,4%, 20,7% y 21,7% después de 24 horas (1/8 4oz, 3/16 6oz y 1/4 4oz, respectivamente). Conclusión: Existe diferencias entre la degradación de la magnitud de las fuerzas de los elásticos y el tiempo de uso empleado en los diferentes tipo de elásticos.Objective: To determine differences between the degradation of the magnitude of the forces of Orthodontic latex elastics and the time used. Materials and methods: In the in vitro study 60 latex elastics of three types (1/4 4oz, 4/16 6oz y 1/6 4oz) of the GAC brand were used, which were stretched three times its internal diameter and immersed in a moist environment at 37 ° C. The magnitudes of the forces were read after 5, 11 and 23 hours using a dynamometer (Gauge Correx®, 250g, Switzerland). ANOVA test as used to identify statistical significant. Results: There was a statistically significant difference (p <0.001) in the three types of elastic. The degradation of the magnitude of force after 5 hours was 20%, 17% and 15.6%; and 23.4%, 20.7% and 21.7% after 24 hours (1/4 4oz, 6oz 4/16 4oz and sixth, respectively). Conclusion: There are differences between the degradation of the magnitude of the forces of the latex elastics and time of use in the different types of elastics. Keywords: Orthodontics, latex elastic, magnitude of the force degradation.Tesi

Submarine geomorphology of the passage of Lanzarote (East Canary Islands region)

International Symposium on Marine Sciences (6º. 2018. Vigo)Centro Oceanográfico de Málaga, Instituto Español de Oceanografía, EspañaCentro oceanográfico de Cádiz, Instituto Español de Oceanografía, EspañaInstituto Geológico y Minero de España, EspañaFacultad de Ciencias del Mar y Ambientales, Universidad de Cádiz, EspañaCentro Oceanográfico de Canarias, Instituto Español de Oceanografía, Españ

Estudio de la forma y tamaño de los incisivos superiores de los estudiantes de odontología según el principio embriogenético de Gerber

The aim of this work was to find the pattern more prevalent according to Gerber’s embriogenetic principle. A sample of 100 students of Dentistry of San Marcos University between 18 and 27 years, without alterations in the upper anterior sector, were examinated clinically, photographic analysis and diagnostic models were conducted. Statistical analysis was performed with the program SPSS 19. Results: the most common biotype (according to Mayoral) was braquifatial (50 %), followed mesofatial (44 %) and dolicofatial (6 %). We find consistent agreement with the second and third postulate of Gerber (2nd postulated: proportion between size of the central incisors and lateral incisors, is similar to proportionbe tween the base and the nasal root; and postulated 3rd: there is a relationship between the angulation of the flat incisal and nasal base line - alar index); but was no agreement with the first postulate (1st postulated: the width of the four incisors would correspond to the length of the width of the nasal base). Also was found the central incisor mesiodistal diameter average 8. 62±0. 52 IC 95 8.55-8.69, side incisor average diameter 7.08±0. 55 IC 95 7.00-7.16 and four incisors diameter (31.07 to 31.75 mm IC 95) altogether, just this last measure there was no coincidence with the nasal base (37.32 to 38.7 mm IC 95). Nasal base was always greater than the diameter of the incisors which makes us understand that it is not a standard reference to select the diameter for aesthetic rebuilders aspects in Peruvian population.El objetivo de éste trabajo fue encontrar el patrón mas prevalente acorde con el principio embriogénico de Gerber. Se trabajó con una muestra de 100 estudiantes de odontología de la UNMSM de ambos sexos entre 18 y 27 años, sin alteraciones en el sector anterosuperior, a los que se les realizó un examen clínico, análisis fotográfico y modelos de estudio. El análisis estadístico se realizó con el programa SPSS 19. Se observó comol biotipo mas frecuente (según Mayoral) el braquifacial (50 %), seguido del mesofacial (44 %) y dólicofacial (6 %), se encontró concordancia con el segundo y tercer postulado de Gerber (2do postulado: proporción de los incisivos centrales y laterales similar a la proporción entre la base y la raíz nasal; y 3er postulado: relación entre la angulación del plano incisal con la línea base nasal -índice alar o índice de Gerber-); pero no se encontró concordancia con el primero postulado (1er postulado: el ancho de los cuatro incisivos correspondería a la longitud del ancho de la base nasal). Se halló el diámetro mesiodistal promedio del incisisvo central 8.62±0.52 IC 95% 8.55-8.69, incisivo lateral 7.08±0.55 IC 95% 7.00-7.16 y de los cuatro incisivos en conjunto (31.07 a 31.75 mm IC 95%), ésta última medida fue la no coincidente con la base nasal (37.32 a 38.7 mm IC 95 %), la cual siempre fue mayor que el diámetro de los incisivos, lo que significa que no puede ser un patrón de referencia para la población peruana para aspectos estéticos reahabilitadores

Reducing pressure ulcers in patients with prolonged acute mechanical ventilation: A quasi-experimental study

Objetivo: Determinar a eficácia de um programa de gestão da qualidade para reduzir a incidência e a gravidade de úlceras por pressão em pacientes de terapia intensiva. Métodos: Estudo com metodologia quasi-experimental, antes-e-depois, conduzido em uma unidade de terapia intensiva clínica e cirúrgica. Incluíram-se os pacientes consecutivos que receberam ventilação mecânica por um período igual ou superior a 96 horas. Uma equipe de Melhoria de Processos delineou um processo de intervenção multifacetado, que consistiu de uma sessão educacional, uma lista de verificação de úlcera de pressão, um aplicativo para smartphone para monitoramento de lesões e um conjunto de normas de tomada de decisão, além de prevenção familiar. Resultados: O Grupo Pré-I incluiu 25 pacientes, e o Grupo Pós-I foi constituído por 69 pacientes. A incidência de úlcera de pressão nestes grupos foi de 41 (75%) e 37 (54%), respectivamente. O tempo mediano para o desenvolvimento das úlceras por pressão foi de 4,5 (4-5) dias no Grupo Pré-I e 9 (6-20) dias no Grupo Pós-I após a admissão para cada um dos períodos. A incidência de úlceras por pressão de grau avançado foi de 27 (49%) no Grupo Pré-I e 7 (10%) no Grupo Pós-I. A presença de úlceras por pressão na alta foi de 38 (69%) e 18 (26%), respectivamente, para os Grupos Pré-I e Pós-I (p < 0,05 para todas as comparações). A participação da família totalizou 9% no Grupo Pré-I e aumentou para 57% no Grupo Pós-I (p < 0,05). Utilizou-se um modelo de regressão logística para analisar os preditores de úlcera de pressão com grau avançado. A duração da ventilação mecânica e a presença de falência de órgão associaram-se positivamente com o desenvolvimento de úlceras por pressão, enquanto o programa multifacetado de intervenção atuou como fator de proteção. Conclusão: Um programa de qualidade, com base em um aplicativo para smartphone e na participação da família, pode reduzir a incidência e a gravidade de úlceras por pressão em pacientes com ventilação mecânica aguda prolongada.Objective: To determine the effectiveness of a quality management program in reducing the incidence and severity of pressure ulcers in critical care patients. Methods: This was a quasi-experimental, before-and-after study that was conducted in a medical-surgical intensive care unit. Consecutive patients who had received mechanical ventilation for ≥ 96 hours were included. A "Process Improvement" team designed a multifaceted interventional process that consisted of an educational session, a pressure ulcer checklist, a smartphone application for lesion monitoring and decision-making, and a "family prevention bundle". Results: Fifty-five patients were included in Pre-I group, and 69 were included in the Post-I group, and the incidence of pressure ulcers in these groups was 41 (75%) and 37 (54%), respectively. The median time for pressure ulcers to develop was 4.5 [4 - 5] days in the Pre-I group and 9 [6 - 20] days in the Post-I group after admission for each period. The incidence of advanced-grade pressure ulcers was 27 (49%) in the Pre-I group and 7 (10%) in the Post-I group, and finally, the presence of pressure ulcers at discharge was 38 (69%) and 18 (26%), respectively (p < 0.05 for all comparisons). Family participation totaled 9% in the Pre-I group and increased to 57% in the Post-I group (p < 0.05). A logistic regression model was used to analyze the predictors of advanced-grade pressure ulcers. The duration of mechanical ventilation and the presence of organ failure were positively associated with the development of pressure ulcers, while the multifaceted intervention program acted as a protective factor. Conclusion: A quality program based on both a smartphone application and family participation can reduce the incidence and severity of pressure ulcers in patients on prolonged acute mechanical ventilation.Facultad de Ciencias Médica

Late gadolinium enhancement distribution patterns in non-ischemic dilated cardiomyopathy: Genotype-phenotype correlation.

AIMS Late gadolinium enhancement (LGE) is frequently found in patients with dilated cardiomyopathy (DCM), there is little information about its frequency and distribution pattern according to underlying genetic substrate. We sought to describe LGE patterns according to genotype and to analyze the risk of major ventricular arrhythmias (MVA) according to patterns. METHODS AND RESULTS Cardiac magnetic resonance findings and LGE distribution according to genetics was performed in a cohort of 600 DCM patients followed at 20 Spanish centers. After exclusion of individuals with multiple causative gene variants or with variants in infrequent DCM-causing genes, 577 patients (34% females, mean age 53.5 years, LVEF 36.9 ± 13.9%) conformed the final cohort. A causative genetic variant was identified in 219 (38%) patients and 147 (25.5%) had LGE. Significant differences were found comparing LGE patterns between genes (P < 0.001). LGE was absent or rare in patients with variants in TNNT2, RBM20 and MYH7 (0%, 5% and 20%, respectively). Patients with variants in DMD, DSP and FLNC showed predominance of LGE subepicardial pattern (50%, 41% and 18%, respectively) whereas patients with variants in TTN, BAG3, LMNA and MYBPC3 showed unspecific LGE patterns. Genetic yield differed according to LGE pattern. Patients with subepicardial, lineal midwall, transmural, right ventricular insertion points or with combination of LGE patterns showed increased risk of MVA compared with patients without LGE. CONCLUSION LGE patterns in DCM has a specific distribution according to the affected gene. Certain LGE patterns are associated with increased risk of MVA and with increased yield of genetic testing.This study has been funded by Instituto Salud Carlos III (ISCIII) through the projects ‘PI18/0004, PI19/01283, and PI20/0320’ (co-funded by the European Regional Development Fund/European Social Fund ‘A way to make Europe’/‘Investing in your future’). The Hospital Universitario Puerta de Hierro, the Hospital Universitario Vall Hebrón, the Hospital General Universitario Gregorio Marañón, and the Hospital Universitario Virgen de la Arrixaca are members of the European Reference Network for Rare, Low Prevalence, and Complex Diseases of the Heart (ERN GUARD-Heart). F.d.F. receives grant support from ISCIII (CM20/00101). R.B. receives funding from the Obra Social la Caixa Foundation. M.B. receives funding from ISCIII (PI19/01283). The CNIC is supported by the ISCIII, Ministerio de Ciencia e Innovación of the Spanish Government (MCIN), and Pro CNIC Foundation.S

Reducing pressure ulcers in patients with prolonged acute mechanical ventilation: A quasi-experimental study

Objetivo: Determinar a eficácia de um programa de gestão da qualidade para reduzir a incidência e a gravidade de úlceras por pressão em pacientes de terapia intensiva. Métodos: Estudo com metodologia quasi-experimental, antes-e-depois, conduzido em uma unidade de terapia intensiva clínica e cirúrgica. Incluíram-se os pacientes consecutivos que receberam ventilação mecânica por um período igual ou superior a 96 horas. Uma equipe de Melhoria de Processos delineou um processo de intervenção multifacetado, que consistiu de uma sessão educacional, uma lista de verificação de úlcera de pressão, um aplicativo para smartphone para monitoramento de lesões e um conjunto de normas de tomada de decisão, além de prevenção familiar. Resultados: O Grupo Pré-I incluiu 25 pacientes, e o Grupo Pós-I foi constituído por 69 pacientes. A incidência de úlcera de pressão nestes grupos foi de 41 (75%) e 37 (54%), respectivamente. O tempo mediano para o desenvolvimento das úlceras por pressão foi de 4,5 (4-5) dias no Grupo Pré-I e 9 (6-20) dias no Grupo Pós-I após a admissão para cada um dos períodos. A incidência de úlceras por pressão de grau avançado foi de 27 (49%) no Grupo Pré-I e 7 (10%) no Grupo Pós-I. A presença de úlceras por pressão na alta foi de 38 (69%) e 18 (26%), respectivamente, para os Grupos Pré-I e Pós-I (p < 0,05 para todas as comparações). A participação da família totalizou 9% no Grupo Pré-I e aumentou para 57% no Grupo Pós-I (p < 0,05). Utilizou-se um modelo de regressão logística para analisar os preditores de úlcera de pressão com grau avançado. A duração da ventilação mecânica e a presença de falência de órgão associaram-se positivamente com o desenvolvimento de úlceras por pressão, enquanto o programa multifacetado de intervenção atuou como fator de proteção. Conclusão: Um programa de qualidade, com base em um aplicativo para smartphone e na participação da família, pode reduzir a incidência e a gravidade de úlceras por pressão em pacientes com ventilação mecânica aguda prolongada.Objective: To determine the effectiveness of a quality management program in reducing the incidence and severity of pressure ulcers in critical care patients. Methods: This was a quasi-experimental, before-and-after study that was conducted in a medical-surgical intensive care unit. Consecutive patients who had received mechanical ventilation for ≥ 96 hours were included. A "Process Improvement" team designed a multifaceted interventional process that consisted of an educational session, a pressure ulcer checklist, a smartphone application for lesion monitoring and decision-making, and a "family prevention bundle". Results: Fifty-five patients were included in Pre-I group, and 69 were included in the Post-I group, and the incidence of pressure ulcers in these groups was 41 (75%) and 37 (54%), respectively. The median time for pressure ulcers to develop was 4.5 [4 - 5] days in the Pre-I group and 9 [6 - 20] days in the Post-I group after admission for each period. The incidence of advanced-grade pressure ulcers was 27 (49%) in the Pre-I group and 7 (10%) in the Post-I group, and finally, the presence of pressure ulcers at discharge was 38 (69%) and 18 (26%), respectively (p < 0.05 for all comparisons). Family participation totaled 9% in the Pre-I group and increased to 57% in the Post-I group (p < 0.05). A logistic regression model was used to analyze the predictors of advanced-grade pressure ulcers. The duration of mechanical ventilation and the presence of organ failure were positively associated with the development of pressure ulcers, while the multifaceted intervention program acted as a protective factor. Conclusion: A quality program based on both a smartphone application and family participation can reduce the incidence and severity of pressure ulcers in patients on prolonged acute mechanical ventilation.Facultad de Ciencias Médica

Seafloor environments on Madrid and El Cid mud volcanoes (Moroccan continental margin of the Gulf of Cádiz)

Simposio sobre el Margen Ibérico Atlántico (9º. 2018. Coimbra, Portugal)More than 70 mud volcanoes (MVs) are identified along the continental margin of the Gulf of Cadiz,,although only a few have been thoroughly sampled and direct observed. This work is a contribution to the knowledge of the Gulf of Cadiz MVs Madrid and El Cid, located in the continental slope known as Western Moroccan Field over 1300 m water depth. On Madrid MV extensive crusts and mud breccia were observed. Nevertheless in El Cid MV, the rocky fragments are of smaller size and mud breccia has not been sampled/observed on the surface. In both MVs, coral reefs colonizing rocky fragments and covering seafloor of metric size have been observed.Departamento de Ciencias de la Tierrra, Universidad de Cádiz, EspañaCentro Oceanográfico de Málaga, Instituto Español de Oceanografía, EspañaCentro oceanográfico de Cádiz, Instituto Español de Oceanografía, EspañaInstituto Geológico y Minero de España, EspañaEstrutura de Missão para a Extensão da Plataforma Continental, Portuga

The avoidance of G-CSF and the addition of prophylactic corticosteroids after autologous stem cell transplantation for multiple myeloma patients appeal for the at-home setting to reduce readmission for neutropenic fever

Autologous stem cell transplantation (ASCT) remains the standard of care for young multiple myeloma (MM) patients; indeed, at-home ASCT has been positioned as an appropriate therapeutic strategy. However, despite the use of prophylactic antibiotics, neutropenic fever (NF) and hospital readmissions continue to pose as the most important limitations in the outpatient setting. It is possible that the febrile episodes may have a non-infectious etiology, and engraftment syndrome could play a more significant role. The aim of this study was to analyze the impact of both G-CSF withdrawal and the addition of primary prophylaxis with corticosteroids after ASCT. Between January 2002 and August 2018, 111 MM patients conditioned with melphalan were managed at-home beginning +1 day after ASCT. Three groups were established: Group A (n = 33) received standard G-CSF post-ASCT; group B (n = 32) avoided G-CSF post-ASCT; group C (n = 46) avoided G-CSF yet added corticosteroid prophylaxis post-ASCT. The incidence of NF among the groups was reduced (64%, 44%, and 24%; P2 (OR 6.1; P = 0.002) and G-CSF avoidance plus corticosteroids (OR 0.1; P<0.001); and for hospital readmission: age �60 years (OR 14.6; P = 0.04) and G-CSF avoidance plus corticosteroids (OR 0.07; P = 0.05. G-CSF avoidance and corticosteroid prophylaxis post ASCT minimize the incidence of NF in MM patients undergoing at-home ASCT. This approach should be explored in a prospective randomized clinical trial

Anales del III Congreso Internacional de Vivienda y Ciudad "Debate en torno a la nueva agenda urbana"

Acta de congresoEl III Congreso Internacional de Vivienda y Ciudad “Debates en torno a la NUEVa Agenda Urbana”, ha sido una apuesta de alto compromiso por acercar los debates centrales y urgentes que tensionan el pleno ejercicio del derecho a la ciudad. Para ello las instituciones organizadoras (INVIHAB –Instituto de Investigación de Vivienda y Hábitat y MGyDH-Maestría en Gestión y Desarrollo Habitacional-1), hemos convidado un espacio que se concretó con potencia en un debate transdisciplinario. Convocó a intelectuales de prestigio internacional, investigadores, académicos y gestores estatales, y en una metodología de innovación articuló las voces académicas con las de las organizaciones sociales y/o barriales en el Foro de las Organizaciones Sociales que tuvo su espacio propio para dar voz a quienes están trabajando en los desafíos para garantizar los derechos a la vivienda y los bienes urbanos en nuestras ciudades del Siglo XXI