218 research outputs found
Developing Organizational Leaders to Manage Publicness: A Conceptual Framework
Students enrolled in programs accredited by the Network of Schools of Public Policy, Affairs, and Administration (NASPAA) are increasingly seeking careers outside of classic government organizations. Considering the diversity of job placements with respect to sector (i.e., government, private for-profit, nonprofit), public affairs students may benefit from in-course instruction that aims to develop management competencies that are applicable to any sector. Educating students on publicness theory, specifically managing to achieve public outcomes (i.e., managing publicness), may position these current and future organizational leaders to identify and effectively manage certain structures and institutions in their organization and the external environment. Accordingly, this study provides a conceptual framework in the form of a research-intensive assignment that will equip public affairs students with a working view of how publicness applies to their organizations. By engaging in this research, students acquire practical tools that allow them to consider publicness in their management strategies and decisions regardless of their sector of employment
Let\u27s talk aspirin: A survey of barriers and facilitators faced by midwives when engaging in conversations about aspirin with women at risk of pre-eclampsia
Infrared and optical properties of pure and cobalt-doped LuNi_2B_2C
We present optical conductivity data for Lu(NiCo)BC over
a wide range of frequencies and temperatures for x=0 and x=0.09. Both materials
show evidence of being good Drude metals with the infrared data in reasonable
agreement with dc resistivity measurements at low frequencies. An absorption
threshold is seen at approximately 700 cm-1. In the cobalt-doped material we
see a superconducting gap in the conductivity spectrum with an absorption onset
at 24 +/- 2 cm-1 = 3.9$ +/- 0.4 k_BT_c suggestive of weak to moderately strong
coupling. The pure material is in the clean limit and no gap can be seen. We
discuss the data in terms of the electron-phonon interaction and find that it
can be fit below 600 cm-1 with a plasma frequency of 3.3 eV and an
electron-phonon coupling constant lambda_{tr}=0.33 using an alpha^{2}F(omega)
spectrum fit to the resistivity.Comment: 10 pages with 10 embedded figures, submitted to PR
Singularities in the optical response of cuprates
We argue that the detailed analysis of the optical response in cuprate
superconductors allows one to verify the magnetic scenario of superconductivity
in cuprates, as for strong coupling charge carriers to antiferromagnetic spin
fluctuations, the second derivative of optical conductivity should contain
detectable singularities at , , and
, where is the amplitude of the
superconducting gap, and is the resonance energy of spin
fluctuations measured in neutron scattering. We argue that there is a good
chance that these singularities have already been detected in the experiments
on optimally doped .Comment: 6 pages, 4 figure
Regulation of Transforming Growth Factor-β1–driven Lung Fibrosis by Galectin-3
Rationale: Idiopathic pulmonary fibrosis (IPF) is a chronic dysregulated response to alveolar epithelial injury with differentiation of epithelial cells and fibroblasts into matrix-secreting myofibroblasts resulting in lung scaring. The prognosis is poor and there are no effective therapies or reliable biomarkers. Galectin-3 is a beta-galactoside binding lectin that is highly expressed in fibrotic tissue of diverse etiologies. Objectives: To examine the role of galectin-3 in pulmonary fibrosis. Methods: We used genetic deletion and pharmacologic inhibition in well-characterized murine models of lung fibrosis. Further mechanistic studies were performed in vitro and on samples from patients with IPF. Measurements and Main Results: Transforming growth factor (TGF)-beta and bleomycin-induced lung fibrosis was dramatically reduced in mice deficient in galectin-3, manifest by reduced TGF-beta 1 induced EMT and myofibroblast activation and collagen production. Galectin-3 reduced phosphorylation and nuclear translocation of beta-catenin but had no effect on Smad2/3 phosphorylation. A novel inhibitor of galectin -3, TD139, blocked TGF-beta-induced beta-catenin activation in vitro and in vivo and attenuated the late-stage progression of lung fibrosis after bleomycin. There was increased expression of galectin-3 in the bronchoalveolar lavage fluid and serum from patients with stable IPF compared with nonspecific interstitial pneumonitis and controls, which rose sharply during an acute exacerbation suggesting that. galectin-3 may be a marker of active fibrosis in IPF and that strategies that block galectin-3 may be effective in treating acute fibrotic exacerbations of IPF. Conclusions: This study identifies galectin-3 as an important regulator of lung fibrosis and provides a proof of principle for galectin-3 inhibition as a potential novel therapeutic strategy for IPF
What drives capacity to innovate? Insights from women and men small-scale farmers in Africa, Asia, and Latin America
What are key characteristics of rural innovators? How are their experiences similar for women
and men, and how are they different? To examine these questions, we draw on individual
interviews with 336 rural women and men known in their communities for trying out new things
in agriculture. The data form part of 84 GENNOVATE community case studies from 19
countries. Building on study participants’ own reflections and experiences with innovation in
their agricultural livelihoods, we combine variable-oriented analysis and analysis of specific
individuals’ lived experience. Results indicate that factors related to personality and agency are
what most drive women’s and men’s capacity to innovate. Access to resources is not a
prerequisite but rather an important enabling aspect. Different types of women have great
potential for local innovation, but structural inequalities make men better positioned to access
resources and leverage support. Men’s support is important when women challenge the status
quo
Flat feline faces: is brachycephaly associated with respiratory abnormalities in the domestic cat (Felis catus)?
There has been little research into brachycephalism and associated disorders in cats. A questionnaire aimed at cat owners was used to determine the relationship between feline facial conformation and owner-reported cat management requirements and respiratory abnormalities. Owner-submitted photographs of cats were used to develop novel measures of skull conformation. One thousand valid questionnaires were received. Within these there were 373 valid photographs that allowed measurement of muzzle ratio (M%) and 494 that allowed nose position ratio (NP%). The data included 239 cats for which both measurements were available. Owners reported lifestyle factors (e.g. feeding type, grooming routine, activity level), physical characteristics (e.g. hair length) and other health characteristics of their cat (e.g. tear staining, body condition score). A composite respiratory score (RS) was calculated for each cat using their owner’s assessment of respiratory noise whilst their cat was asleep and then breathing difficulty following activity. Multivariate analyses were carried out using linear models to explore the relationship between RS and facial conformation, and lifestyle risk factors. The results showed that reductions in NP% and M% were significantly associated with RS (P < 0.001 and P = 0.026, respectively) and that the relationship was significantly negatively correlated (r = -0.56, P < 0.001 for both). Respiratory score was also significantly associated with increased presence of tear staining (P < 0.001) and a sedentary lifestyle (P = 0.01). This study improves current knowledge concerning cats with breeding-related alterations in skull confirmation and indicates that brachycephalism may have negative respiratory implications for cat health and welfare, as has been previously shown in dogs
Engaging fringe stakeholders in business and society research: applying visual participatory research methods
Business and society (B&S) researchers, as well as practitioners, have been critiqued for ignoring those with less voice and power (e.g. women, non-literate or indigenous peoples) often referred to as ‘fringe stakeholders’. Existing methods used in B&S research often fail to address issues of meaningful participation, voice and power, especially in developing countries. In this article we stress the utility of visual participatory research (VPR) methods in B&S research to fill this gap. Through a case study on engaging Ghanaian cocoa farmers on gender inequality issues we explore how VPR methods may be used by researchers to achieve more inclusive, and thus more credible, stakeholder research that can improve decision-making within businesses. Furthermore, we argue that ingrained social and environmental problems tackled by B&S research and the unique context in which they occur may open up new opportunities to develop participatory visual methods for social change
Próximos pasos del NAMA GanaderÃa en Costa Rica: SÃntesis de las consultas con actores y evaluación rápida de su estado actual
La NAMA GanaderÃa de Costa Rica tiene como
objetivo realizar un cambio en la forma de
producción del sector ganadero costarricense
con miras a una ganaderÃa eco-competitiva.
Las alianzas público-privadas-académicas
evalúan y co-desarrollan los elementos técnicos
e institucionales necesarios para construir la
NAMA.
Los componentes clave del desarrollo de la
NAMA en su primera fase piloto (2013-2021)
están bien encaminados para desarrollar una
propuesta robusta hacia el escalonamiento e
implementación de las metas propuestas a 2030
- …