23 research outputs found

    Государственная власть как правовая категория: понятие, сущность и признаки

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    This article analyzes the fundamental issues of the evolution of approaches to the legal category of state power. The authors consider the phenomenon of power as one of the most important types of social interaction. The authors show that during this evolution, along with the preservation of universal (essential) characteristics due to the nature and social purpose of the state, there is a modification of those properties and characteristics of state power that have a specific historical character and depend on many factors affecting ways of implementing state power. The article reveals the main types of state power and methods of its implementation. According to the authors, the power is not the result of only violence, the suppression of one person by another, but comes from the very nature of man. The authors reveal the category of “state power” by examining its content, characteristics, elements, subjects, and objects. They examine the ways of expressing political power as a type of domination of the corresponding social group depending on a particular historical type of society.Este artículo analiza los problemas fundamentales de la evolución de los enfoques a la categoría legal del poder estatal. Los autores consideran el fenómeno del poder como uno de los tipos más importantes de interacción social. Los autores muestran que, durante esta evolución, junto con la preservación de las características universales (esenciales) debido a la naturaleza y el propósito social del estado, hay una modificación de aquellas propiedades y características del poder estatal que tienen un carácter histórico específico y dependen de Muchos factores afectan las formas de implementar el poder del Estado. El artículo revela los principales tipos de poder estatal y los métodos para su implementación. Según los autores, el poder no es el resultado de solo violencia, la supresión de una persona por otra, sino que proviene de la naturaleza misma del hombre. Los autores revelan la categoría de "poder estatal" al examinar su contenido, características, elementos, sujetos y objetos. Examinan las formas de expresar el poder político como un tipo de dominación del grupo social correspondiente dependiendo de un tipo histórico particular de sociedad.В данной статье анализируются основные вопросы эволюции подходов к правовой категории государственной власти. Авторы рассматривают феномен власти как один из важнейших видов социального взаимодействия. Авторы показывают, что в ходе этой эволюции наряду с сохранением универсальных (существенных) характеристик, обусловленных природой и социальным предназначением государства, происходит модификация тех свойств и характеристик государственной власти, которые имеют специфический исторический характер и зависят от множество факторов, влияющих на способы осуществления государственной власти. В статье раскрыты основные виды государственной власти и методы ее реализации. По мнению авторов, власть не является результатом только насилия, подавления одного человека другим, а исходит из самой природы человека. Авторы раскрывают категорию «государственная власть», изучая ее содержание, характеристики, элементы, предметы и объекты. Они исследуют способы выражения политической власти как тип доминирования соответствующей социальной группы в зависимости от определенного исторического типа общества

    Diffusion-kurtosis magnetic resonance imaging of the brain in the differential diagnostics of metastases of tumors of various primary localization

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    Background: Metastatic brain lesions lead to the most unfavorable prognosis for the course of an oncological disease. Most often, brain metastases arise from primary tumors such as lung cancer, breast cancer, and melanoma. Of particular interest are groups of secondary intracranial tumors without an identified primary focus. Methods of non-invasive differential diagnosis based on a possible histological affiliation, including diffusion-kurtosis magnetic resonance imaging, can improve the diagnostic search for the primary tumor. Aim: The aim of this study is to improve the quality of differential diagnosis for brain metastases of tumors of different primary localization by introducing the diffusion-kurtosis magnetic resonance imaging technique into the magnetic resonance scanning protocol. Methods: Our work included studies of 60 patients who underwent examination and treatment at the N.N. Blokhin National Research Medical Center of Oncology of the Ministry of Health of Russia from October 2019 to March 2022. According to magnetic resonance imaging, metastatic formations were detected in the brain of the patients, with different localizations of the primary tumor. 20 patients were diagnosed with lung cancer (33.3%), 20 patients with breast cancer (33.3%) and 20 patients with melanomas (33.3%). We evaluated the tumor size, diffusion and kurtosis parameters, such as the mean kurtosis, axial kurtosis, radial kurtosis, kurtosis anisotropy, radial diffusion, and fractional anisotropy, and relative anisotropy, axial diffusion of the extra-axonal fluid, radial diffusion of the extra-axonal fluid, axonal fluid fraction, and tortuosity of the diffusion trajectory. Results: Statistically significantly (p 0.05) differing parameters of diffusion and kurtosis in the comparative evaluation of the above indicators were identified in the structure associated with melanoma and lung cancer axial diffusion, fractional anisotropy, relative anisotropy, radial kurtosis and tortuosity of the diffusion trajectory, as well as in the structure of melanoma and breast cancer — axial diffusion, axonal fluid fraction, fractional anisotropy, axial diffusion of extra-axonal fluid, mean kurtosis, relative anisotropy, radial kurtosis and tortuosity of the diffusion trajectory. Conclusion: Diffusion-kurtosis magnetic resonance imaging is a promising technique that allows obtaining additional differential information in the case of metastatic lesions of the brain matter, especially those from an undetected primary focus

    Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

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    Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
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