10 research outputs found
O Barão de Hirsch e a imigração judaica para o Novo Mundo
Get PDFPesquisadora francesa escreve sobre o Barão de Hirsch. Baron von Hirsch and the Jewish immigration in the New World - The French researcher writes about Baron von Hirsch.
TUDO SE ILUMINA COMO ROMANCE DE MISE-EN-ABYME: VIAGENS E ESCRITAS COMO FORMAS DE ACESSO AOS ARQUIVOS JUDAICOS E FAMILIARES
Full text linkO Barão de Hirsch e a imigração judaica para o Novo Mundo
No full textPesquisadora francesa escreve sobre o Barão de Hirsch. Baron von Hirsch and the Jewish immigration in the New World - The French researcher writes about Baron von Hirsch.
“A new book in Jewish affairs begins”: Maurice de Hirsch and the waning power of Jewish philanthropy at the Fin-de-Siècle
No full textAnti-inflammatory effects of melatonin in multiple sclerosis
No full textMelatonin is a hormone with complex roles in the pathogenesis of autoimmune disorders. Over the years, it has become clear that melatonin may exacerbate some autoimmune conditions, whereas it alleviates others such as multiple sclerosis. Multiple sclerosis is an autoimmune disorder characterized by a dysregulated immune response directed against the central nervous system. Indeed, the balance between pathogenic CD4+ T cells secreting IFN-γ (TH1) or IL-17 (TH17); and FoxP3+ regulatory T cells and IL-10+ type 1 regulatory T cells (Tr1 cells) is thought to play an important role in disease activity. Recent evidence suggests that melatonin ameliorates multiple sclerosis by controlling the balance between effector and regulatory cells, suggesting that melatonin-triggered signaling pathways are potential targets for therapeutic intervention. Here, we review the available data on the effects of melatonin on immune processes relevant for MS and discuss its therapeutic potential.Fil: Farez, Mauricio Franco. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación para la Lucha Contra las Enfermedades Neurológicas de la Infancia. Instituto de Investigaciones Neurológicas "Raúl Carrea"; ArgentinaFil: Calandri, Ismael L.. Fundación para la Lucha Contra las Enfermedades Neurológicas de la Infancia. Instituto de Investigaciones Neurológicas "Raúl Carrea"; ArgentinaFil: Correale, Jorge. Fundación para la Lucha Contra las Enfermedades Neurológicas de la Infancia. Instituto de Investigaciones Neurológicas "Raúl Carrea"; ArgentinaFil: Quintana, Francisco J.. Harvard Medical School; Estados Unidos. The Broad Institute; Estados Unido
