643 research outputs found

    Austrians-in-the-World. Conversations and Debates About Planning And Development

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    John Friedmann has taught at MIT, the Pontifical Catholic University of Chile, UCLA, the University of Melbourne, the National University of Taiwan, and is currently an Honorary Professor in the School of Community and Regional Planning at the University of British Columbia in Vancouver, Canada. Throughout his life, he has been an advisor to governments in Brazil, Venezuela, Chile, Mozambique, and China where he was appointed Honorary Foreign Advisor to the China Academy of Planning and Urban Design

    Policy responses to rapid urbanization in the third world

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    The following two papers (printed as Part 1 and 2) were prepared for delivery at the University of Witwatersrand, Johannesburg, South Africa, April/ May 1983

    Association of school absence and exclusion with recorded neurodevelopmental disorders, mental disorders, or self-harm: a nationwide, retrospective, electronic cohort study of children and young people in Wales, UK

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    BackgroundPoor attendance at school, whether due to absenteeism or exclusion, leads to multiple social, educational, and lifelong socioeconomic disadvantages. We aimed to measure the association between a broad range of diagnosed neurodevelopmental and mental disorders and recorded self-harm by the age of 24 years and school attendance and exclusion.MethodsIn this nationwide, retrospective, electronic cohort study, we drew a cohort from the Welsh Demographic Service Dataset, which included individuals aged 7–16 years (16 years being the school leaving age in the UK) enrolled in state-funded schools in Wales in the academic years 2012/13–2015/16 (between Sept 1, 2012, and Aug 31, 2016). Using the Adolescent Mental Health Data Platform, we linked attendance and exclusion data to national demographic and primary and secondary health-care datasets. We identified all pupils with a recorded diagnosis of neurodevelopmental disorders (ADHD and autism spectrum disorder [ASD]), learning difficulties, conduct disorder, depression, anxiety, eating disorders, alcohol or drugs misuse, bipolar disorder, schizophrenia, other psychotic disorders, or recorded self-harm (our explanatory variables) before the age of 24 years. Outcomes were school absence and exclusion. Generalised estimating equations with exchangeable correlation structures using binomial distribution with the logit link function were used to calculate odds ratios (OR) for absenteeism and exclusion, adjusting for sex, age, and deprivation.FindingsSchool attendance, school exclusion, and health-care data were available for 414 637 pupils (201 789 [48·7%] girls and 212 848 [51·3%] boys; mean age 10·5 years [SD 3·8] on Sept 1, 2012; ethnicity data were not available). Individuals with a record of a neurodevelopmental disorder, mental disorder, or self-harm were more likely to be absent or excluded in any school year than were those without a record. Unadjusted ORs for absences ranged from 2·1 (95% CI 2·0–2·2) for those with neurodevelopmental disorders to 6·6 (4·9–8·3) for those with bipolar disorder. Adjusted ORs (aORs) for absences ranged from 2·0 (1·9–2·1) for those with neurodevelopmental disorders to 5·5 (4·2–7·2) for those with bipolar disorder. Unadjusted ORs for exclusion ranged from 1·7 (1·3–2·2) for those with eating disorders to 22·7 (20·8–24·7) for those with a record of drugs misuse. aORs for exclusion ranged from 1·8 (1·5–2·0) for those with learning difficulties to 11·0 (10·0–12·1) for those with a record of drugs misuse.InterpretationChildren and young people up to the age of 24 years with a record of a neurodevelopmental or mental disorder or self-harm before the age of 24 years were more likely to miss school than those without a record. Exclusion or persistent absence are potential indicators of current or future poor mental health that are routinely collected and could be used to target assessment and early intervention. Integrated school-based and health-care strategies to support young peoples' engagement with school life are required.FundingThe Medical Research Council, MQ Mental Health Research, and the Economic and Social Research Council.TranslationFor the Welsh translation of the abstract see Supplementary Materials section

    A Microscopic Model for D-Wave Pairing in the Cuprates: What Happens when Electrons Somersault?

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    We present a microscopic model for a strongly repulsive electron gas on a 2D square lattice. We suggest that nearest neighbor Coulomb repulsion stabilizes a state in which electrons undergo a "somersault" in their internal spin-space (spin-flux). When this spin-1/2 antiferromagnetic (AFM) insulator is doped, the charge carriers nucleate mobile, charged, bosonic vortex solitons accompanied by unoccupied states deep inside the Mott-Hubbard charge-transfer gap. This model provides a unified microscopic basis for (i) non-Fermi-liquid transport properties, (ii) mid-infrared optical absorption, (iii) destruction of AFM long range order with doping, (iv) angled resolved spectroscopy (ARPES), and (v) d-wave preformed charged carrier pairs. We use the Configuration Interaction (CI) method to study the quantum translational and rotational properties of such pairs. The CI method systematically describes fluctuation and quantum tunneling corrections to the Hartree-Fock approximation and recaptures essential features of the (Bethe ansatz) exact solution of the Hubbard model in 1D. For a single hole in the 2D AFM plane, we find a precursor to spin-charge separation. The CI ground state consists of a bound vortex-antivortex pair, one vortex carrying the charge and the other one carrying the spin of the doping hole.Comment: 10 pages, 8 figure

    Prospectus, February 12, 1971

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    S.A.S.L.A. IS STARTED FOR STUDENT BENEFIT: ILLIACS TO TAKE ACTION; Veterans Association Co-Sponsors Boy Scouts; Problems Of Our Times: This Business Of Space; Letters To Editor; An Editorial; Bull Page: Coffee House, New Club, Family Night, SASLA, W. I. U. Transfer, SWAMP, Fail Safe, Vets Meeting, Hotline, Gemini House, Wit N\u27 Wisdom, No Paper; Champion Gymnast Teaches At Parkland; Parkland Wins Triangular; Parkland Defeats Lincoln Land; District Playoffs Announced; Mad Dogs Win Green Division; Swim Meet Belley Flops; Intramural Playoffs; Indoor Track Schedule; Intramural Standings; Track Team Shows Strengthhttps://spark.parkland.edu/prospectus_1971/1012/thumbnail.jp

    Do rural migrants 'float' in urban China? Neighbouring and neighbourhood sentiment in Beijing

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    Urban China reached 50% of the nation’s population by 2010, mainly as a result of massive rural–urban migration. There is substantial evidence of their social marginality in terms of occupational and housing opportunities. Here we ask about their incorporation into the neighbourhoods where they live. Rural migrants are called the ‘floating population’ in China, suggesting that their residence in the city is only temporary and that they are unlikely to develop strong local ties. This study contrasts the neighbourhood socialising of migrant tenants with that of urban homeowners who were born in the city. It draws on original survey research in Beijing that included questions on relations with neighbours and neighbourhood sentiment. It is found that migrants are more likely to engage in socialising and exchange of help with neighbours, and consequently their neighbouring helps strengthen their sentiment towards the neighbourhoods where they live. It is argued that contemporary social changes – including rising education and homeownership – may actually reduce neighbouring, while rural migrants’ marginality makes them more dependent on their local social network

    The Grizzly, April 6, 1979

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    International House Postponed • Friedmann To Edit Ruby • New Deanship Filled • Changes Announced In Staff • Clean Mailroom - How Long? • Nuclear Energy: Worth the Risk? • Ursinus College International House: An Idea Whose Time has Come (Almost) • Roving Reporter: Grizzly opinions? • Letters to the Editor: President responds • WRUC Last Hope For Radio • Feit Forum: Origins On Earth • Audio Corner: Tape decks • Portrait Of The Professor: Dr. William Williamson • Ursinus News In Brief: Judiciary board suspends two; Honor society seeks applicants; Two to take sabbaticals; Board Approves Cost Increases • Lacrosse Starts Second Year • Golfers Start Strong • Spring Fling • Sports Profile: Eric Rea • Bear Baseball On The Roll • Men\u27s Tennis Starts 0-4https://digitalcommons.ursinus.edu/grizzlynews/1017/thumbnail.jp

    Prospectus, May 7, 1971

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    PREPAREDNESS PROGRAM GIVES SECOND CHANCE; VIC Helps To Rehabilitate Youth; Nurses, Hygienists In Health Week ; One Way or Two?; Student Deferment May End; One Man Band; Bull Sheet: Elections, Game Week, Sisters, Hot Line, Wit n\u27 Wisdom, Counselor Appts., Tau Epsilon, Voting, New Paperbacks, Anti War Activities, IOC, Vets Meeting, About Drugs, Need Help, Book Depository, LRC File, Poncho Pilot; Parkland Belts Walbash Twice; P.C. Board Holds Elections-- Consider Nepotism Policy; PC Faculty Art Exhibit; Know Your Candidate: Student Government Elections, Will They Pass or Fail?; David A. Friedmann, President; Robert D. Bales, President; John Stuckey, Vice President; Bob Hilton, Treasurer; Diane Topping, Secretary; Becky Terrell, Convocations; Terry Cassidy, Campus Organizationshttps://spark.parkland.edu/prospectus_1971/1007/thumbnail.jp

    Characterization of Aptamer-Protein Complexes by X-ray Crystallography and Alternative Approaches

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    Aptamers are oligonucleotide ligands, either RNA or ssDNA, selected for high-affinity binding to molecular targets, such as small organic molecules, proteins or whole microorganisms. While reports of new aptamers are numerous, characterization of their specific interaction is often restricted to the affinity of binding (KD). Over the years, crystal structures of aptamer-protein complexes have only scarcely become available. Here we describe some relevant technical issues about the process of crystallizing aptamer-protein complexes and highlight some biochemical details on the molecular basis of selected aptamer-protein interactions. In addition, alternative experimental and computational approaches are discussed to study aptamer-protein interactions.
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