2,102 research outputs found

    Sneutrino as Lightest Supersymmetric Particle in B3 mSUGRA Models and Signals at the LHC

    Full text link
    We consider B3 mSUGRA models where we have one lepton number violating LQD operator at the GUT scale. This can alter the supersymmetric mass spectrum leading to a sneutrino as the lightest supersymmetric particle in a large region of parameter space. We take into account the restrictions from neutrino masses, the muon anomalous magnetic moment, b -> s gamma and other precision measurements. We furthermore investigate existing restrictions from direct searches at LEP, the Tevatron and the CERN p\bar p collider. We then give examples for characteristic signatures at the LHC.Comment: 22 pages, 11 figure

    A comparison of 111In-DOTATOC and 111In-DOTATATE: biodistribution and dosimetry in the same patients with metastatic neuroendocrine tumours

    Get PDF
    [Yttrium-90-DOTA-Tyr3]-octreotide (DOTATOC) and [177Lu-DOTA-Tyr3-Thr8]-octreotide (DOTATATE) are used for peptide receptor-mediated radionuclide therapy (PRMRT) in neuroendocrine tumours. No human data comparing these two compounds are available so far. We used 111In as a surrogate for 90Y and 177Lu and examined whether one of the 111In-labelled peptides had a more favourable biodistribution in patients with neuroendocrine tumours. Special emphasis was given to kidney uptake and tumour-to-kidney ratio since kidney toxicity is usually the dose-limiting factor. Five patients with metastatic neuroendocrine tumours were injected with 222MBq 111In-DOTATOC and 111In-DOTATATE within 2 weeks. Up to 48h after injection, whole-body scans were performed and blood and urine samples were collected. The mean absorbed dose was calculated for tumours, kidney, liver, spleen and bone marrow. In all cases 111In-DOTATATE showed a higher uptake (%IA) in kidney and liver. The amount of 111In-DOTATOC excreted into the urine was significantly higher than for 111In-DOTATATE. The mean absorbed dose to the red marrow was nearly identical. 111In-DOTATOC showed a higher tumour-to-kidney absorbed dose ratio in seven of nine evaluated tumours. The variability of the tumour-to-kidney ratio was high and the significance level in favour of 111In-DOTATOC was P=0.065. In five patients the pharmacokinetics of 111In-DOTATOC and 111In-DOTATATE was found to be comparable. The two peptides appear to be nearly equivalent for PRMRT in neuroendocrine tumours, with minor advantages for 111In/90Y-DOTATOC; on this basis, we shall continue to use 90Y-DOTATOC for PRMRT in patients with metastatic neuroendocrine tumour

    Isotope shift in the dielectronic recombination of three-electron ^{A}Nd^{57+}

    Get PDF
    Isotope shifts in dielectronic recombination spectra were studied for Li-like ^{A}Nd^{57+} ions with A=142 and A=150. From the displacement of resonance positions energy shifts \delta E^{142,150}(2s-2p_1/2)= 40.2(3)(6) meV (stat)(sys)) and \delta E^{142,150}(2s-2p_3/2) = 42.3(12)(20) meV of 2s-2p_j transitions were deduced. An evaluation of these values within a full QED treatment yields a change in the mean-square charge radius of ^{142,150}\delta = -1.36(1)(3) fm^2. The approach is conceptually new and combines the advantage of a simple atomic structure with high sensitivity to nuclear size.Comment: 10 pages, 3 figures, accepted for publication in Physical Review Letter

    Novel Reconstruction Mechanism for Dangling-Bond Minimization: Combined Method Surface Structure Determination of SiC(111)-(3×3)

    Get PDF
    The SiC(111)−(3×3) phase was analyzed by scanning tunneling microscopy (STM), low-energy electron diffraction (LEED) holography, density functional theory (DFT), and conventional LEED. A single adatom per unit cell found in STM acts as a beam splitter for the holographic inversion of discrete LEED spot intensities. The resulting 3D image guides the detailed analyses by LEED and DFT which find a Si tetramer on a twisted Si adlayer with cloverlike rings. This twist model with one dangling bond left per unit cell represents a novel (n×n)-reconstruction mechanism of group-IV (111) surfaces

    Social Preferences, Skill Segregation and Wage Dynamics

    Get PDF
    We study the earning structure and the equilibrium asignment of workers to firms in a model in which workers have social preferences, and skills are perfectly substitutable in production. Firms offer long-term contracts, and we allow for frictions in the labour market in the form of mobility costs. The model delivers specific predictions about the nature of worker flows, about the characteristic of workplace skill segregation, and about wage dispersion both within and cross firms. We shows that long-term contracts in the resence of social preferences associate within-firm wage dispersion with novel "internal labour market" features such as gradual promotions, productivity-unrelated wage increases, and downward wage flexibility. These three dynamic features lead to productivity-unrelated wage volatily within firms.Publicad

    examples of high-impact discoveries from an international chemistry network

    Get PDF
    CNPq 303355/2018-2 CAPES-Cofecub (88887.130198/2017-01) EP/F034210/1 EP/P030572/1 UIDB/50006/2020 CNPq (308383/2018-4 Universal 403866/2016-2 PDE 204177/2018-9 I 421703/2017-2 .During the last 150 years or more, society has witnessed many key scientific discoveries and inventions, which have dramatically improved not only our quality of life, but our lifespan. However, the motivation of scientists to provide scientific advances has generally not been the achievement of these goals, but mainly driven by research curiosity. Fundamental scientific studies, also known as basic science, have paved the way to a society of knowledge by means of continuously evolving education systems, and have led to applied science and technological breakthroughs changing the World. However, without basic science such life-changing advances would not happen, which is poorly understood by the society. Having this in mind, chemists and biochemists working in a chemistry network highlight here examples of how basic science has played a crucial role and led to major breakthroughs. In seven short stories, the authors describe cases and historical events where basic research discoveries have advanced science, and opened avenues for future achievements. Investment in basic science is crucial for a nation’s health and wealth. The support of scientists driven by curiosity ultimately can benefit the whole of society, not only in innovative products, but also in the improvement of the understanding of our own lives.publishersversionpublishe

    HIGH TEMPERATURE CORROSION STUDY INTERIM REPORT FOR THE PERIOD NOVEMBER 1958 THROUGH MAY 1959

    Get PDF
    Samples of grade A Monel snd grade A nickel were subjected statically in a single reactor to an undiluted atmosphere of gaseous fluorine at pressures up to one atmosphere absolute and temperatures up to 1500 deg F. The grade A Monel was conservatively estimated to have consumed at least 40 times as much fluorine as grade A nickel during the entire period of the investigation. Samples of fused alpha Al/sub 2/O/sub 3/, alpha -Al/sub 2/O/sub 3/- MgO spinel, and alpha -Al/sub 2/O/sub 3/-NiO--nickel cermet were exposed to undiluted fluorine at one atinosphere absolute pressure at temperatures of 1340 and 1500 deg F. Results indicated that the alpha -Al/sub 2/O/sub 3/ is as good as the Ni in the region of 1300 deg F. Grade A nickel samples coated with nickel fluoride filins of 37,000 and 74,000 A, respectively, were exposed to an absolute pressure of gaseous UF/sub 6/ of 12 cm of Hg at temperatures of 1000 and 1800 deg F. (W.L.H.

    The heme-based oxygen sensor Rhizobium etli FixL: influence of auxiliary ligands on heme redox potential and implications on the enzyme activity

    Get PDF
    Conformational changes associated to sensing mechanisms of heme-based protein sensors are a key molecular event that seems to modulate not only the protein activity but also the potential of the Fe redox couple of the heme domain. In this work, midpoint potentials (E) assigned to the Fe redox couple of the heme domain of FixL from Rhizobium etli (ReFixL) in the unliganded and liganded states were determined by spectroelectrochemistry in the presence of inorganic mediators. In comparison to the unliganded ReFixL protein (+ 19 mV), the binding to ligands that switch off the kinase activity induces a negative shift, i. e. E = − 51, − 57 and − 156 mV for O, imidazole and CN, respectively. Upon binding to CO, which does not affect the kinase active, E was observed at + 21 mV. The potential values observed for Fe of the heme domain of ReFixL upon binding to CO and O do not follow the expected trend based on thermodynamics, assuming that positive potential shift would be expected for ligands that bind to and therefore stabilize the Fe state. Our results suggest that the conformational changes that switch off kinase activity upon O binding have knock-on effects to the local environment of the heme, such as solvent rearrangement, destabilize the Fe state and counterbalances the Fe-stabilizing influence of the O ligand

    Dynamics of Fermionic Four-Wave Mixing

    Full text link
    We study the dynamics of a beam of fermions diffracted off a density grating formed by fermionic atoms in the limit of a large grating. An exact description of the system in terms of particle-hole operators is developed. We use a combination of analytical and numerical methods to quantitatively explore the Raman-Nath and the Bragg regimes of diffraction. We discuss the limits in diffraction efficiency resulting from the dephasing of the grating due the distribution of energy states occupied by the fermions. We propose several methods to overcome these limits, including the novel technique of ``atom echoes''.Comment: 8 pages, 7 figure
    • 

    corecore