280 research outputs found

    Magnetoelastic effects in multiferroic YMnO3_3

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    We have investigated magnetoelastic effects in multiferroic YMnO3_3 below the antiferromagnetic phase transition, TN70T_N \approx 70 K, using neutron powder diffraction. The aa lattice parameter of the hexagonal unit cell of YMnO3_3 decreases normally above TNT_N, but decreases anomalously below TN_N, whereas the cc lattice parameter increases with decreasing temperature and then increases anomalously below TN_N. The unit cell volume also undergoes an anomalous contraction below TNT_N. By fitting the background thermal expansion for a non-magnetic lattice with the Einstein-Gr\"uneisen equation, we determined the lattice strains Δa\Delta a, Δc\Delta c and ΔV\Delta V due to the magnetoelastic effects as a function of temperature. We have also determined the temperature variation of the ordered magnetic moment of the Mn ion by fitting the measured Bragg intensities of the nuclear and magnetic reflections with the known crystal and magnetic structure models and have established that the lattice strain due to the magnetoelastic effect in YMnO3_3 couples with the square of the ordered magnetic moment or the square of the order parameter of the antiferromagnetic phase transition

    Алгоритм определения оптимального числа волокон используемых при внутритканевой фотодинамической терапии рака молочной железы на основании диффузионного уравнения

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    It is essential in interstitial Photodynamic therapy (iPDT) treatment planning to ensure a homogeneous distribution within a tumor volume using cylindrical diffusing fibers while keeping the surrounding tissue intact. Light distribution is simulated through two algorithms based on the diffusion equation assuming diffusers as light sources. The first algorithm analyzes the diffusion equation and studies the effects of different variables (optical properties, delivered power, diffuser length, and position). Next, optical properties of breast were applied to estimate the volume that receives accepted light dose from one diffuser. In the second algorithm, multiple diffusers were simulated in order to find the relation between the volume and the number of required diffusers which are needed to cover cubical or cylindrical volume with sufficient light dose. Throughout this study, real values of optical properties, clinical laser power, and treatment time were considered to evaluate sufficient light doses. This study is in agreement with previous works in that optical properties are the major factors influencing light distribution in iPDT. It is shown that for a homogeneous phantom mimicking breast cancer and cubical or cylindrical shape, the number of required fibers N equal W×L or D2 respectively.При планировании внутритканевой фотодинамической терапии (iPDT ) с использованием цилиндрических диффузных волокон важно обеспечить однородное распределение света по всему объему опухоли, сохранив при этом целостность окружающей ткани. Авторы данной статьи смоделировали распределение света с помощью двух алгоритмов, основанных на уравнении диффузии, в которых в качестве источников света используются цилиндрические диффузоры. Первый алгоритм анализирует уравнение диффузии и изучает влияние различных переменных (оптических свойств источника, применяемой мощности, длины диффузора и его положения). Затем были использованы параметры оптических свойств молочной железы для оценки объема, который рассчитывает световую дозу от одного диффузора. Во втором алгоритме было смоделировано несколько рассеивателей для нахожде ния соотношения между объемом и количеством рассеивателей, необходимых для покрытия кубического или цилиндрического объема достаточной световой дозой. На протяжении всего этого исследования рассматривались реальные значения оптических свойств, клинической мощности лазера и времени лечения для оценки достаточных световых доз. Это исследование согласуется с предыдущими работами в том, что оптические свойства являются основными факторами, влияющими на распределение света при iPDT. Показано, что, для однородного фантома, имитирующего рак молочной железы, кубической или цилиндрической формы, количество требуемых волокон N равно W×L или D2 , соответственно

    Comparison between the Efficiency of Heterojunction Thin Film InGaP\GaAs\Ge and InGaP\GaAs Solar Cell

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    This paper presents the design parameters for a thin film 3J InGaP/GaAs/Ge solar cell with a simulated maximum efficiency of 32.11% using Tcad Silvaco. Design parameters include the doping concentration, molar fraction, layers’ thickness and tunnel junction characteristics. An initial dual junction InGaP/GaAs model of a previous published heterojunction cell was simulated in Tcad Silvaco to accurately predict solar cell performance. To improve the solar cell’s performance, we have fixed meshing, material properties, models and numerical methods. However, thickness and layer doping concentration were taken as variables. We, first simulate the InGaP\GaAs dual junction cell by changing the doping concentrations and thicknesses which showed an increase in efficiency. Next, a triple junction InGaP/GaAs/Ge cell was modeled by adding a Ge layer to the previous dual junction InGaP/GaAs model with an InGaP /GaAs tunnel junction

    A SEMELHANÇA DE FIGURAS NO ENSINO DA GEOMETRIA PLANA VITÓRIA

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    Este trabalho consiste em realizar um estudo aprofundado sobre semelhança de figuras planas, a partir de um conhecimento prévio dos conceitos básicos de geometria plana. Além da teoria, abordada nos três primeiros capítulos e voltada principalmente para professores de matemática, encontram-se também, nos três capítulos subsequentes, exercícios resolvidos tradicionalmente e também resolvidos utilizando o software GeoGebra, além de exercícios propostos juntamente com suas respectivas respostas esperadas

    A RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migration.

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    The leading edge of migrating cells contains rapidly translocating activated integrins associated with growing actin filaments that form 'sticky fingers' to sense extracellular matrix and guide cell migration. Here we utilized indirect bimolecular fluorescence complementation to visualize a molecular complex containing a Mig-10/RIAM/lamellipodin (MRL) protein (Rap1-GTP-interacting adaptor molecule (RIAM) or lamellipodin), talin and activated integrins in living cells. This complex localizes at the tips of growing actin filaments in lamellipodial and filopodial protrusions, thus corresponding to the tips of the 'sticky fingers.' Formation of the complex requires talin to form a bridge between the MRL protein and the integrins. Moreover, disruption of the MRL protein-integrin-talin (MIT) complex markedly impairs cell protrusion. These data reveal the molecular basis of the formation of 'sticky fingers' at the leading edge of migrating cells and show that an MIT complex drives these protrusions

    Magnetic superelasticity and inverse magnetocaloric effect in Ni-Mn-In

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    Applying a magnetic field to a ferromagnetic Ni50_{50}Mn34_{34}In16_{16} alloy in the martensitic state induces a structural phase transition to the austenitic state. This is accompanied by a strain which recovers on removing the magnetic field giving the system a magnetically superelastic character. A further property of this alloy is that it also shows the inverse magnetocaloric effect. The magnetic superelasticity and the inverse magnetocaloric effect in Ni-Mn-In and their association with the first order structural transition is studied by magnetization, strain, and neutron diffraction studies under magnetic field.Comment: 6 pages, 8 figures. Published in the Physical Review

    Magnetic superelasticity and inverse magnetocaloric effect in Ni-Mn-In

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    Applying a magnetic field to a ferromagnetic Ni50_{50}Mn34_{34}In16_{16} alloy in the martensitic state induces a structural phase transition to the austenitic state. This is accompanied by a strain which recovers on removing the magnetic field giving the system a magnetically superelastic character. A further property of this alloy is that it also shows the inverse magnetocaloric effect. The magnetic superelasticity and the inverse magnetocaloric effect in Ni-Mn-In and their association with the first order structural transition is studied by magnetization, strain, and neutron diffraction studies under magnetic field.Comment: 6 pages, 8 figures. Published in the Physical Review

    The immunophenotype of adult t acute lymphoblastic leukemia in Morocco

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    Background: There is paucity of detailed studies of adult T cell acute lymphoblastic leukemia (T-ALL) in developing countries reflecting the condition of these patients including clinical and biological features. Objective: This study was carried out to analyze the immunophenotypic characteristics of 40 Moroccan patients with T-ALL and its association with biological and clinical features. Patients and Methods: Between 2006 and 2009, 130 adult patients diagnosed with acute lymphoblastic leukemia (ALL) were immunophenotyped by 3-color flow cytometry using a panel of monoclonal antibodies. Cases presenting features of a T-lineage phenotype were subjected to detailed analysis including immunophenotypic, clinical and biological parameters. Results: Proportion of T-ALL among ALL Moroccan patients was 31.0%. Median age of patients was 28 years. Twenty-nine patients were females and 11 were males. 45.0% of patients (18/40) had features of immature T-ALL stages (pro-T and pre-T ALL), 30.0% (12/40) of CD1a+ cortical T-ALL stage and 25.0% (10/40) had a characteristic phenotype of medullary T-ALL. The frequencies of progenitor cell markers CD10, CD34 and TdT expression were 14.0; 57.5% and 50.0% respectively. The aberrant expression of B li­neage associated antigen CD79a were positive in 20.5% of the cases and the aberrant expression of myeloid antigens CD13 and/or CD33 was found in 22 (55.0%) cases. No significant association was encountered between TdT, CD34 or myeloid antigens positivity and high risk features at presentation as age, sex, and white blood cells. However, myeloid antigens (CD13 and/or CD33) was significantly associated with T-cell maturation stages (p = 0.009). Conclusion: To the best of our knowledge, this is the first report from North Africa of immunophenotypic study on adult T-ALL. Our findings indicate that the proportion of T-ALL among ALL in Morocco is similar to that reported in others Mediterranean countries like France and Italy and that myeloid-associated antigens expression is frequently associated with immature immunophenotype. Key Words: adult T cell acute lymphoblastic leukemia, immunophenotypic analysis, immunological subtypes, myeloid and T-cell antigens
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