Experimental investigation of the stability of Fe-rich carbonates in the lower mantle

International audienceThe fate of carbonates in the Earth's mantle plays a key role in the geodynamical carbon cycle. Although iron is a major component of the Earth's lower mantle, the stability of Fe-bearing carbonates has rarely been studied. Here we present experimental results on the stability of Fe-rich carbonates at pressures ranging from 40 to 105 GPa and temperatures of 1450-3600 K, corresponding to depths within the Earth's lower mantle of about 1000-2400 km. Samples of iron oxides and iron-magnesium oxides were loaded into CO2 gas and laser heated in a diamond-anvil cell. The nature of crystalline run products was determined in situ by X-ray diffraction, and the recovered samples were studied by analytical transmission electron microscopy and scanning transmission X-ray microscopy. We show that Fe-(II) is systematically involved in redox reactions with CO2 yielding to Fe-(III)-bearing phases and diamonds. We also report a new Fe-(III)-bearing high-pressure phase resulting from the transformation of FeCO3 at pressures exceeding 40 GPa. The presence of both diamonds and an oxidized C-bearing phase suggests that oxidized and reduced forms of carbon might coexist in the deep mantle. Finally, the observed reactions potentially provide a new mechanism for diamond formation at great depth

Composition of the Earth's Inner Core from High-pressure Sound Velocity Measurements in Fe-Ni-Si alloys

International audienceWe performed room-temperature sound velocity and density measurements on a polycrystalline alloy, Fe0.89Ni0.04Si0.07, in the hexagonal close-packed (hcp) phase up to 108 GPa. Over the investigated pressure range the aggregate compressional sound velocity is ∼9% higher than in pure iron at the same density. The measured aggregate compressional (VP) and shear (VS) sound velocities, extrapolated to core densities and corrected for anharmonic temperature effects, are compared with seismic profiles. Our results provide constraints on the silicon abundance in the core, suggesting a model that simultaneously matches the primary seismic observables, density, P-wave and S-wave velocities, for an inner core containing 4 to 5 wt.% of Ni and 1 to 2 wt.% of Si

Control of replication stress and mitosis in colorectal cancer stem cells through the interplay of PARP1, MRE11 and RAD51

Cancer stem cells (CSCs) are tumor subpopulations driving disease development, progression, relapse and therapy resistance, and their targeting ensures tumor eradication. CSCs display heterogeneous replication stress (RS), but the functionality/relevance of the RS response (RSR) centered on the ATR-CHK1 axis is debated. Here, we show that the RSR is efficient in primary CSCs from colorectal cancer (CRC-SCs), and describe unique roles for PARP1 and MRE11/RAD51. First, we demonstrated that PARP1 is upregulated in CRC-SCs resistant to several replication poisons and RSR inhibitors (RSRi). In these cells, PARP1 modulates replication fork speed resulting in low constitutive RS. Second, we showed that MRE11 and RAD51 cooperate in the genoprotection and mitosis execution of PARP1-upregulated CRC-SCs. These roles represent therapeutic vulnerabilities for CSCs. Indeed, PARP1i sensitized CRC-SCs to ATRi/CHK1i, inducing replication catastrophe, and prevented the development of resistance to CHK1i. Also, MRE11i + RAD51i selectively killed PARP1-upregulated CRC-SCs via mitotic catastrophe. These results provide the rationale for biomarker-driven clinical trials in CRC using distinct RSRi combinations

Seismic detection of the martian core by InSight

A plethora of geophysical, geo- chemical, and geodynamical observations indicate that the terrestrial planets have differentiated into silicate crusts and mantles that surround a dense core. The latter consists primarily of Fe and some lighter alloying elements (e.g., S, Si, C, O, and H) [1]¿. The Martian meteorites show evidence of chalcophile element depletion, suggesting that the otherwise Fe-Ni- rich core likely contains a sulfide component, which influences physical state

Seismic detection of the martian core

Clues to a planet's geologic history are contained in its interior structure, particularly its core. We detected reflections of seismic waves from the core-mantle boundary of Mars using InSight seismic data and inverted these together with geodetic data to constrain the radius of the liquid metal core to 1830 +/- 40 kilometers. The large core implies a martian mantle mineralogically similar to the terrestrial upper mantle and transition zone but differing from Earth by not having a bridgmanite-dominated lower mantle. We inferred a mean core density of 5.7 to 6.3 grams per cubic centimeter, which requires a substantial complement of light elements dissolved in the iron-nickel core. The seismic core shadow as seen from InSight's location covers half the surface of Mars, including the majority of potentially active regions-e.g., Tharsis-possibly limiting the number of detectable marsquakes.This is InSight contribution 200. We acknowledge NASA, CNES, and partner agencies and institutions (UKSA, SSO, ESA-PRODEX, DLR, JPL, IPGP-CNRS, ETHZ, IC, and MPS-MPG) for the development of SEIS. Numerical simulations were supported by a grant from the Swiss National Supercomputing Centre (CSCS) under project ID s922 as well as HPC resources of CINES under the allocation A0090407341, made by GENCI. We thank B. Dintrans, director of CINES, for his efficient handling of our request for computational time. Figures were created using matplotlib (83), seismic data processing was done in ObsPy (84), and numerical evaluation was done in NumPy and SciPy (85, 86). Funding: S.C.S., A.K., D.G., J.C., A.C.D., G.Z., and N.D. acknowledge support from ETHZ through the ETH+ funding scheme (ETH+2 19-1: “Planet MARS”). S.C.S. acknowledges funding from ETH research grant ETH-10 17-3. W.B.B., A.G.M., M.P.P., and S.E.S. were supported by the NASA InSight mission and funds from the Jet Propulsion Laboratory, California Institute of Technology, under a contract with the National Aeronautics and Space Administration (80NM0018D0004). D.A. has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant agreement 724690). The French teams acknowledge support from CNES as well as Agence Nationale de la Recherche (ANR-14-CE36-0012-02 and ANR-19-CE31-0008-08). A.R. was financially supported by the Belgian PRODEX program managed by the European Space Agency in collaboration with the Belgian Federal Science Policy Office. M.S. wishes to thank SANIMS (RTI2018-095594-B-I00). M.v.D. received support from the ERC under the European Union’s Horizon 2020 program (grant no. 714069). D.S. and C.S. acknowledge funding from ETH research grant ETH-06 17-02. J.C.E.I. acknowledges support from NASA grant 80NSSC18K1633. N.S., D.K., Q.H., R.M., V.L., and A.G.M. acknowledge NASA grant 80NSSC18K1628 for support. V.L. acknowledges support from the Packard Foundation. W.T.P. and C.C. received funding from the UK Space Agency, grant ST/S001239/1. A.H. was funded by the UK Space Agency (grant ST/R002096/1). A.-C.P. acknowledges the financial support and endorsement from the DLR Management Board Young Research Group Leader Program and the Executive Board Member for Space Research and Technology. Author contributions: S.C.S., D.G., S.C., R.F.G., Q.H., D.K., V.L., M.S., N.S., D.S., É.S., C.S., and G.Z. analyzed the seismic data and made ScS arrival time picks. S.C.S., P.L., D.G., Z.X., C.C., and W.T.P. performed the statistical analysis of the observed signals. S.C.S., Q.H., N.S., R.M., and A.G.M. identified the arrivals as ScS waves based on interior models from A.K., H.S., and A.R. A.K., M.D., A.C.D., and H.S. performed the inversions. S.C.S., A.K., P.L., D.G., D.A., J.C.E.I., M.K., C.P., A.-C.P., A.R., T.G., and S.E.S. participated and contributed to the interpretation of the results. Review of the continuous data and detection of marsquakes was done by S.C.S., S.C., G.Z., C.C., N.D., J.C., M.v.D., T.K., M.P., and A.H. with operational support by É.B., C.P., and P.M.D. S.C.S. and A.K. wrote the central part of the paper with contributions from H.S., N.S., D.A., J.C.E.I., A.G.M., A.-C.P., A.R., J.C., and M.v.D. J.C.E.I., R.M., M.K., and V.L. reviewed the contributions to the supplementary materials. The InSight mission is managed by W.B.B., M.P.P., and S.E.S. The SEIS instrument development was led by P.L., D.G., W.T.P., and W.B.B. Supplementary section 1 was written by M.S., D.S., and É.S. with contributions from S.C.S., C.S., and Z.X. Supplementary section 2 was written by D.K. and V.L. with contributions from J.C.E.I. and N.S. Supplementary section 3 was written by M.S. and É.S. Supplementary section 4 was written by R.F.G. with contributions from M.D. Supplementary section 5 was written by Q.H. with contributions from N.S. Supplementary section 6 was written by S.C.S. with contributions from the authors of the other supplements. Supplementary section 7 was written by Z.X. and C.C. with contributions from P.L. and W.T.P. Supplementary section 8 was written by A.K., M.D., A.C.D., and H.S. Supplementary section 9 was written by M.D. Supplementary section 10 was written by A.C.D., A.K., and M.D. Supplementary section 11 was written by D.A. and A.R. with contributions from A.K. Competing interests: The authors declare that they have no competing interests. Data and materials availability: We thank the operators of JPL, SISMOC, MSDS, IRIS-DMC, and PDS for providing SEED SEIS data (87). Three hundred interior models derived in this study are available from MSDS (88)

Seismic Constraints on the Thickness and Structure of the Martian Crust from InSight

NASA¿s InSight mission [1] has for the first time placed a very broad-band seismometer on the surface of Mars. The Seismic Experiment for Interior Structure (SEIS) [2] has been collecting continuous data since early February 2019. The main focus of InSight is to enhance our understanding of the internal structure and dynamics of Mars, which includes the goal to better constrain the crustal thickness of the planet [3]. Knowing the present-day crustal thickness of Mars has important implications for its thermal evolution [4] as well as for the partitioning of silicates and heat-producing elements between the different layers of Mars. Current estimates for the crustal thickness of Mars are based on modeling the relationship between topography and gravity [5,6], but these studies rely on different assumptions, e.g. on the density of the crust and upper mantle, or the bulk silicate composition of the planet and the crust. The resulting values for the average crustal thickness differ by more than 100%, from 30 km to more than 100 km [7]. New independent constraints from InSight will be based on seismically determining the crustal thickness at the landing site. This single firm measurement of crustal thickness at one point on the planet will allow to constrain both the average crustal thickness of Mars as well as thickness variations across the planet when combined with constraints from gravity and topography [8]. Here we describe the determination of the crustal structure and thickness at the InSight landing site based on seismic receiver functions for three marsquakes compared with autocorrelations of InSight data [9].We acknowledge NASA, CNES, partner agencies and institutions (UKSA, SSO,DLR, JPL, IPGP-CNRS, ETHZ, IC, MPS-MPG) and the operators of JPL, SISMOC, MSDS, IRIS-DMC and PDS for providing SEED SEIS data. InSight data is archived in the PDS, and a full list of archives in the Geosciences, Atmospheres, and Imaging nodes is at https://pds-geosciences.wustl.edu/missions/insight/. This work was partially carried out at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with the National Aeronautics and Space Administration. ©2021, California Institute of Technology. Government sponsorship acknowledge

The interior of Mars as seen by InSight (Invited)

InSight is the first planetary mission dedicated to exploring the whole interior of a planet using geophysical methods, specifically seismology and geodesy. To this end, we observed seismic waves of distant marsquakes and inverted for interior models using differential travel times of phases reflected at the surface (PP, SS...) or the core mantle-boundary (ScS), as well as those converted at crustal interfaces. Compared to previous orbital observations1-3, the seismic data added decisive new insights with consequences for the formation of Mars: The global average crustal thickness of 24-75 km is at the low end of pre-mission estimates5. Together with the the thick lithosphere of 450-600 km5, this requires an enrichment of heat-producing elements in the crust by a factor of 13-20, compared to the primitive mantle. The iron-rich liquid core is 1790-1870 km in radius6, which rules out the existence of an insulating bridgmanite-dominated lower mantle on Mars. The large, and therefore low-density core needs a high amount of light elements. Given the geochemical boundary conditions, Sulfur alone cannot explain the estimated density of ~6 g/cm3 and volatile elements, such as oxygen, carbon or hydrogen are needed in significant amounts. This observation is difficult to reconcile with classical models of late formation from the same material as Earth. We also give an overview of open questions after three years of InSight operation on the surface of Mars, such as the potential existence of an inner core or compositional layers above the CM

The seismicity of Mars

The InSight (Interior Exploration using Seismic Investigations, Geodesy and Heat Transport) mission landed in Elysium Planitia on Mars on 26 November 2018 and fully deployed its seismometer by the end of February 2019. The mission aims to detect, characterize and locate seismic activity on Mars, and to further constrain the internal structure, composition and dynamics of the planet. Here, we present seismometer data recorded until 30 September 2019, which reveal that Mars is seismically active. We identify 174 marsquakes, comprising two distinct populations: 150 small-magnitude, high-frequency events with waves propagating at crustal depths and 24 low-frequency, subcrustal events of magnitude Mw 3–4 with waves propagating at various depths in the mantle. These marsquakes have spectral characteristics similar to the seismicity observed on the Earth and Moon. We determine that two of the largest detected marsquakes were located near the Cerberus Fossae fracture system. From the recorded seismicity, we constrain attenuation in the crust and mantle, and find indications of a potential low-S-wave-velocity layer in the upper mantle. © 2020, The Author(s), under exclusive licence to Springer Nature Limited.We acknowledge NASA, CNES and its partner agencies and institutions (UKSA, SSO, DLR, JPL, IPGP-CNRS, ETHZ, IC and MPS-MPG) and the flight operations team at JPL, SISMOC, MSDS, IRIS-DMC and PDS for providing SEIS data. The Swiss co-authors were jointly funded by (1) the Swiss National Science Foundation and French Agence Nationale de la Recherche (SNF-ANR project 157133 ‘Seismology on Mars’), (2) the Swiss National Science Foundation (SNF project 172508 ‘Mapping the internal structure of Mars’), (3) the Swiss State Secretariat for Education, Research and Innovation (SEFRI project ‘MarsQuake Service-Preparatory Phase’) and (4) ETH Research grant no. ETH-06 17-02. Additional support came from the Swiss National Supercomputing Centre (CSCS) under project ID s922. The Swiss contribution in the implementation of the SEIS electronics was made possible by funding from the federal Swiss Space Office (SSO) and contractual and technical support from the ESA-PRODEX office. The French Team acknowledge the French Space Agency CNES, which has supported and funded all SEIS-related contracts and CNES employees, as well as CNRS and the French team universities for personal and infrastructure support. Additional support was provided by ANR (ANR-14-CE36-0012-02 and ANR-19-CE31-0008-08) and, for the IPGP team, by the UnivEarthS Labex programme (ANR-10-LABX-0023), IDEX Sorbonne Paris Cité (ANR-11-IDEX-0005-0). SEIS-SP development and delivery were funded by the UK Space Agency. A portion of the work was carried out at the InSight Project at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with the National Aeronautics and Space Administration. The MPS SEIS team acknowledges funding for development of the SEIS leveling system by the DLR German Space Agency. We thank gempa GmbH for software development related to the MQS tools. This paper is InSight contribution number 102.Peer reviewe