4,339 research outputs found

    Proses Penyusunan Uraian Pekerjaan Berdasarkan Tahapan Analisis Pekerjaan Staf Administrasi Underwriting pada Perusahaan Asuransi Umum

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    A Company needs to carry out job analysis, because job analysis is one of process to get an overview of the work. Job analysis has phases which will generate job description and job specification effectively and efficiently. The purpose of this research is to know the process of the preparation of job description based on phases of job analysis administration underwriting/claim staff, technique section in company and the methods used to conduct research is by interview and the data of the company. The result showed that the company carried out phases are, planning job analysis, preparing job analysis, implementation job analysis, and evaluation job analysis of the phases, the phases generate job description. Keywords: , job analysis, insurance, process, job description

    Alterations in reproductive hormones during heat stress in dairy cattle

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    In dairy cows inseminated during the hot months of the year, there is a decrease in fertility. Different factors contribute to this situation; the most important are a consequence of increased temperature and humidity that result in a decreased expression of overt estrus and a reduction in appetite and dry matter intake. Heat stress reduces the degree of dominance of the selected follicle and this can be seen as reduced steroidogenic capacity of its theca and granulosa cells and a fall in blood estradiol concentrations. Plasma progesterone levels can be increased or decreased depending on whether the heat stress is acute or chronic, and on the metabolic state of the animal. These endocrine changes reduce follicular activity and alter the ovulatory mechanism, leading to a decrease in oocyte and embryo quality. The uterine environment is also modified, reducing the likelihood of embryo implantation. Systems activated by heat stress can influence reproduction at the hypothalamus, pituitary gland or gonads. However, the major impact is thought to be within the brain or at the pituitary gland. Measurement of plasma concentrations of the gonadotrophins provides a good indication of the effects at these higher levels, since the pulsatile secretion of luteinizing hormone (LH) is a reflection of the secretion of gonadotropin-releasing hormone (GnRH) from the hypothalamus. Both the secretion and actions of GnRH are influenced by the feedback actions of gonadal sex steroids and inhibin. Recent studies suggest that the use of gonadotropins to induce follicular development and ovulation can decrease the severity of seasonal postpartum infertility in dairy cows.Key words: Reproductive hormones, dairy cow and heat stress

    Optimized intermolecular potential for nitriles based on Anisotropic United Atoms model

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    An extension of the Anisotropic United Atoms intermolecular potential model is proposed for nitriles. The electrostatic part of the intermolecular potential is calculated using atomic charges obtained by a simple Mulliken population analysis. The repulsion-dispersion interaction parameters for methyl and methylene groups are taken from transferable AUA4 literature parameters [Ungerer et al., J. Chem. Phys., 2000, 112, 5499]. Non-bonding Lennard-Jones intermolecular potential parameters are regressed for the carbon and nitrogen atoms of the nitrile group (–C≡N) from experimental vapor-liquid equilibrium data of acetonitrile. Gibbs Ensemble Monte Carlo simulations and experimental data agreement is very good for acetonitrile, and better than previous molecular potential proposed by Hloucha et al. [J. Chem. Phys., 2000, 113, 5401]. The transferability of the resulting potential is then successfully tested, without any further readjustment, to predict vapor-liquid phase equilibrium of propionitrile and n-butyronitrile

    Altruism during predation in an assassin bug

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    Zelus annulosus is an assassin bug species mostly noted on Hirtella physophora, a myrmecophyte specifically associated with the ant Allomerus decemarticulatus known to build traps on host tree twigs to ambush insect preys. The Z. annulosus females lay egg clutches protected by a sticky substance. To avoid being trapped, the first three instars of nymphs remain grouped in a clutch beneath the leaves on which they hatched, yet from time to time, they climb onto the upper side to group ambush preys. Long-distance prey detection permits these bugs to capture flying or jumping insects that alight on their leaves. Like some other Zelus species, the sticky substance of the sundew setae on their forelegs aids in prey capture. Group ambushing permits early instars to capture insects that they then share or not depending on prey size and the hunger of the successful nymphs. Fourth and fifth instars, with greater needs, rather ambush solitarily on different host tree leaves, but attract siblings to share large preys. Communal feeding permits faster prey consumption, enabling small nymphs to return sooner to the shelter of their leaves. By improving the regularity of feeding for each nymph, it likely regulates nymphal development, synchronizing molting and subsequently limiting cannibalism

    Evaluation of the sleep modulating effects of methanolic extracts of Strychnos spinosa and Strychnos innocua fruits in mice

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    This study aimed to evaluate the sleep modulating properties of Strychnos spinosa and Strychnos innocua fruits in Swiss albino mice. The depressant effect of the extracts on the central nervous system was studied using a diazepam-induced sleep model in mice. The mice were divided into four groups of six mice each. The test groups received Strychnos spinosa and Strychnos innocua fruits extracts at the doses of 250, 500, and 1000 mg/kg body weight intraperitoneally. In contrast, the control group received distilled water at 10 ml/kg. Diazepam (Ranbaxy®, India) was used as a standard drug and administered 30 minutes after the initial treatment. The lethal doses (LD50) of the two extracts were estimated to be >5000 mg/kg. The results obtained from the onset of sleep of rats administered methanol extracts of Strychnos spinosa, and Strychnos innocua fruits showed that the extracts at 250, 500, and 1000 mg/kg, respectively, did not significantly (p >0.05) alter the onset of sleep when compared with the control. The onset of sleep in the groups treated with Strychnos spinosa fruit extracts indicated a dose-dependent decrease pattern. The study also revealed a prolonged duration of sleep in all the experimental groups treated with the two extracts compared to the control group. The treated groups of 250, 500 and 1000 mg/kg significantly (p <0.05) prolonged the duration of diazepam-induced sleep in a dose-dependent manner when compared to the control group. The group treated with 1000 mg/kg of Strychnos innocua fruit extract was significant (p <0.05) compared to the control group. In conclusion, the high LD50 observed in this study suggests that the two extracts are relatively safe and contain promising bioactive ingredients that cause sleep modulation in mice

    Dark energy accretion onto black holes in a cosmic scenario

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    In this paper we study the accretion of dark energy onto a black hole in the cases that dark energy is equipped with a positive cosmological constant and when the space-time is described by a Schwarzschild-de Sitter metric. While the first case is the same as the usual accretion procedure for a more complicated fluid, the second one give rise to a consistent cosmic scenario for the mentioned phenomenon. © Springer Science+Business Media, LLC 2009.This paper was supported by MEC under Research Project Nº FIS2005-01181, and by the Research Cooperation Project CSIC-CNRST. P.M.-M. acknowledges CSIC and ESF for a I3P grant.Peer Reviewe

    EVALUATION OF BIOMASS PRODUCTION, CAROTENOID LEVEL AND ANTIOXIDANT CAPACITY PRODUCED BY THERMUS FILIFORMIS USING FRACTIONAL FACTORIAL DESIGN

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    Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)A fractional factorial design 2(5-1) was used to evaluate the effect of temperature, pH, and concentrations of yeast extract, tryptone and Nitsch's trace elements on the biomass, total carotenoids and protection against singlet oxygen by carotenoid extracts of the bacterium Thermus filiformis. In addition, the carotenoid composition was determined by high-performance liquid chromatography connected to a diode array and mass spectrometer detectors (HPLC-DAD-MS/MS). The production of biomass ranged from 0.113 to 0.658 g/L, the total carotenoid from 137.6 to 1,517.4 mu g/g and the protection against singlet oxygen from 4.3 to 85.1 %. Results of the fractional factorial design showed that temperature had a negative effect on biomass production and a positive effect on carotenoid content and protection against singlet oxygen, besides, high levels of pH value, concentrations of yeast extract and tryptone had a positive effect on biomass production only at lower temperatures. The main carotenoids of T. filiformis were thermozeaxanthins. In the tested conditions, changes in the levels of the variables influenced the biomass, carotenoid production, and protection against singlet oxygen, although they did not influence the carotenoid profile. The results of this study provide a better understanding on the interactions among certain nutritional and cultivation conditions of a thermophile bacterium, Thermus filiformis, on biomass and carotenoid amounts, as well as on the antioxidant capacity.431126134Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq

    How and why DNA barcodes underestimate the diversity of microbial eukaryotes

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    Background: Because many picoplanktonic eukaryotic species cannot currently be maintained in culture, direct sequencing of PCR-amplified 18S ribosomal gene DNA fragments from filtered sea-water has been successfully used to investigate the astounding diversity of these organisms. The recognition of many novel planktonic organisms is thus based solely on their 18S rDNA sequence. However, a species delimited by its 18S rDNA sequence might contain many cryptic species, which are highly differentiated in their protein coding sequences. Principal Findings: Here, we investigate the issue of species identification from one gene to the whole genome sequence. Using 52 whole genome DNA sequences, we estimated the global genetic divergence in protein coding genes between organisms from different lineages and compared this to their ribosomal gene sequence divergences. We show that this relationship between proteome divergence and 18S divergence is lineage dependant. Unicellular lineages have especially low 18S divergences relative to their protein sequence divergences, suggesting that 18S ribosomal genes are too conservative to assess planktonic eukaryotic diversity. We provide an explanation for this lineage dependency, which suggests that most species with large effective population sizes will show far less divergence in 18S than protein coding sequences. Conclusions: There is therefore a trade-off between using genes that are easy to amplify in all species, but which by their nature are highly conserved and underestimate the true number of species, and using genes that give a better description of the number of species, but which are more difficult to amplify. We have shown that this trade-off differs between unicellular and multicellular organisms as a likely consequence of differences in effective population sizes. We anticipate that biodiversity of microbial eukaryotic species is underestimated and that numerous ''cryptic species'' will become discernable with the future acquisition of genomic and metagenomic sequences
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