Pathomorphological Changes in Poultry Pasteurellios, Pullorosis and Colibacteriosis Diseases

The organism of chicken infected with individual pathogens exhibits relatively simple patho-anatomical modifications in the presence of two or three separate bacterial pathogens. Because it is highly challenging to differentiate between mixed bacterial infections based just on clinical symptoms, pathologoanatomical examination and distinction are preferred. These disorders will be accurately diagnosed promptly and without delay if the pathologo-anatomical investigations are properly examined, and preventive measures will be consistently applied

Comprehensive assessment of the quality of life of patients with glaucoma when using various methods of treatment

Background. Research and maintenance of an acceptable quality of life is considered to be the main aim of treating chronic incurable disease including glaucoma.The aim. To perform a comprehensive assessment of the quality of life of patients with glaucoma when using various types of surgical and conservative treatment before treatment and 1 month after treatment.Material and methods. We carried out a randomized controlled study which included 229 patients, divided into 2 groups. The first group of patients (133 people) received various types of surgical intervention for glaucoma, consisted of 6 subgroups. They had the following types of surgeries: sinus trabeculectomy with the use of “Glautex” drainage implant; classical sinus trabeculectomy; sinus trabeculectomy with implantation of drainage made of a collagen hemostatic foam; transscleral laser cyclocoagulation of the ciliary body; cataract phacoemulsification in comorbid primary open-angle glaucoma and in primary closed-angle glaucoma. The second group consisted of 96 patients who received conservative treatment; it consisted of 4 subgroups. Patients of subgroups of the 2nd group received various types of conservative therapy against the background of local antihypertensive therapy: complex treatment with the use of vasoprotectives, vitamins, nootropics in a hospital setting; neuroprotective therapy in the form of Retinalamin intramuscular injection. After receiving informed voluntary consent to participate in the study, all patients underwent a comprehensive assessment of the quality of life using universal, specific and psychological questionnaires (SF-36, visual analogue scale, EQ-5D, VFQ-25, GQL-15, VF-14 and HADS) before treatment and 1 month after treatment.Results. The therapy had a positive effect on the quality of life in both groups of patients, however the most pronounced positive dynamics is registered in patients having conservative therapy as compared with those having surgical treatment. The use of valid, reliable questionnaires makes it possible to fully assess the quality of life in glaucoma

Remote Prophylaxis of Social and Educational Adaptation of University International Entrants in Total Pandemic

The relevance of the study is due to the trends of the global pandemic, which provoked an extremal transition of all areas of higher education to distance learning, as the only possible way to work with domestic and international entrants and students. In addition, the trends of the pandemic in the current educational environment also determine the special need to develop remote mechanisms for a prophylaxis approach to solving the problems of social and educational adaptation of international entrants – future University students. In this regard, this article is aimed at identifying the features of remote prophylaxis of social and educational adaptation of entrants. The article reveals the transformation of social and educational adaptation of international entrants in the global pandemic; defines the structure and content of remote prophylaxis of social and educational adaptation of international University entrants in the global pandemic. Based on the results of the research, the authors of the article substantiate the prophylaxis model of the educational and software complex for remote prophylaxis of social and educational adaptation of University international entrants. The effectiveness of the model is proved by the results of its use in the process of remote social and educational adaptation of University international entrants in the context of a global pandemic. The materials of the article have practical application and can be useful in the development and implementation of various methods and practices of social and educational adaptation of international entrants – future University students in the context of a global pandemic. It is recommended for University teachers and students, methodologists, curators, Tutors

STUDENT ATTITUDE TO DEMOGRAPHIC SITUATION IN RUSSIA

Purpose of the study: Since the new generation is the main entity of material and social benefits’ renewal process of any state, the article aims to identify the students’ attitude to the demographic situation in Russia. It is the younger generation of different age groups that is the main labor unit of the state population. Relevant is the fact that the issues of demography are a global challenge of self-organizing society.  The purpose of the article is to identify the students’ attitude to the demographic situation in Russia, as well as to consider various models of reproductive behavior. Methodology: The leading methods for the study of this problem is the survey method, which allows to make a qualitative analysis of the characteristics of the students’ attitude to the demographic situation in Russia and to establish the subjective position of students regarding demographic development. Results: The article reveals that the following administrative and legal measures contribute to the improvement of the demographic situation in the country (legislative acts regulating the marriage age, divorce, attitude to abortion and contraception, the status of mother and children in the divorce, working women’s labor regime); economic measures (paid leave, various benefits at child’s birth, preferential credit conditions if necessary, tax and housing benefits); educational measures (formation of public opinion, the core and standards of demographic behavior, determination of attitude to religious norms, traditions and customs, family planning policy, sexual education of youth). The authors established a high level of awareness of students about the demographic situation in the country; the presence of anxiety about this situation. Applications of this study: The data obtained in the work can be used in sociology, social psychology, political science, as well as for further theoretical development of this issue. Novelty/Originality of this study: The study revealed a high level of awareness of young people about the demographic situation in the country, certain anxiety about this situation. However, young people are not in a hurry to participate in the solution of demographic problems, referring mainly to the difficulties of material nature. This indicates the need for more careful consideration of measures of state support for young families, taking into account the research of their opinion on this matter

Parameters of passive working bodies of potato digging machine

The major working housing of potato digging machines is a plowshare on which energy costs and the quality of potato digging depend. The examination aims to justify the parameters of the plowshare and the divider of the combined digging working body. The constructive scheme of a potato-digging machine with a combined digging working body, the results of theoretical studies on the substantiation of the primary parameters of the main and intermediate plowshares and the divider, are presented. A special laboratory installation was used to conduct experiments. During the experiments, dividers with different capture widths were made, and the angle of the plowshare installation to the horizon was changed. The degree of damage and loss of the tuber and the traction resistance of the plowshares were taken as evaluation criteria. The outcome of the experimental investigation to determine the parameters of the plowshare is presented. Based on theoretical studies, analytical dependencies, and mathematical models were obtained that allow determining the parameters of the plowshare and the divider of the potato digging machine. It was found that for intensive destruction of the tuberous formation with minimal energy consumption and uniform transportation, the width of the colter of the combined working housing must be 45 cm, the perspective of the plowshare razor solution 90°, the perspective of inclination of the plowshare to the skyline within 27-30°, the length of the plowshare 40 cm, the width of the divider should be 45 cm, its length 39 cm, the angle the solution is 60°, the angle of installation of the working surface to the horizon in the transversely vertical plane is 65° and the range from the toe of the intermediate plowshare to the divider is 32.6 cm

New materials for the electromechanical and acoustoelectric transducers

The technology for creation of the polymer-microsized piezoelectriccomposite substrate is developed by employing the electric gas dis-charge plasma method. It is determined experimentally that as aresult of the nano-structurization of the volume of the polymer-pie-zoceramic composite close to the surface it is Young and piezo-modulus as well as the mechanical quality and electromechanicalcoupling coefficients and the dielectric constant has been increased,whereas, tangent losses are decreased depending on the type of thenanoparticle and its volume rate

ЭФФЕКТИВНОСТЬ ИСПОЛЬЗОВАНИЯ ВЫСОКОБЕЛКОВЫХ КОРМОВЫХ ДОБАВОК В РАЦИОНАХ КОРОВ

In the Republic of Tajikistan, linseeds, cotton seeds and rape seeds are used for producing vegetable oil. The authors highlight that until now the impact of cotton, linseed and rapeseed cake, which are seen as high-protein feed additives, on the dairy productivity, composition and properties of milk are not sufficiently investigated for the conditions of the country. The paper highlights the results of two scientific and economic experiments on investigation of the impact caused by cotton, linseed and rapeseed cake on the milk productivity, quality and physical and chemical parameters of milk of highproductive cows of the Black-and-WhiteTajik type breed. The researchers found out that application of various seed cakes when feeding cows in DIM increases the milk yield and improves the quality and physical and chemical parameters of milk. The authors observed experimental cows which received different types of seed cake and the milk their produced and found out that experimental cows exceeded 5.9-12.3 % according to the parameters of milk of natural fat; 4% milk - on 12.0-17.9 %. The cows from experimental groups produced 6.55-11.51 kg milk fat more. Feed costs in energetic feed unit pro 1 kg of 4-% -milk were 7.7-15.2% lower in the experimental groups of cows in comparison with the control group. According to organoleptic and sanitary-hygienic parameters, the milk produced by the cows from experimental groups was of higher quality and fulfilled the requirements of the state standard for purchased milk. Fat concentration increased on0.08-0.19%; total protein - on 0.07-0.15, dry skimmed milk residue - on 0.07-0.16 and dry matter - on 0.15-0.35%. According to the chemical composition, the milk produced by cows, which were fed with linseed cake was the best one. The content of milk sugar, ash, calcium and phosphorus was approximately the same in all the groups. The cost of 1 centner of milk in the experimental groups was 6.3-12.7% lower, and the profitability level of milk production was 9.8-16.3% higher in comparison with the control groups.В Республике Таджикистан для производства растительного масла наряду с семенами хлопчатника используют семена льна и рапса. Однако до настоящего времени в условиях республики вопросы влияния хлопчатникового, льняного и рапсового жмыхов, которые являются высокобелковыми кормовыми добавками, на молочную продуктивность, состав и свойства молока коров остаются не изученными. В данной статье изложены результаты двух научно-хозяйственных опытов по изучению влияния хлопчатникового, льняного и рапсового жмыхов на молочную продуктивность, качество и физико-химические показатели молока высокопродуктивных коров таджикского типа черно-пестрой породы. Установлено, что использование различных жмыхов в кормлении коров в период раздоя повышает молочность коров, улучшает качество и физико-химические показатели молока. По удою молока натуральной жирности опытные группы коров, получавшие различные виды жмыха, превосходили контрольных на 5,9–12,3, а по удою 4%-го молока – на 12,0–17,9%. От коров опытных групп получено на 6,55–11,51 кг больше молочного жира. Затраты кормов в ЭКЕ на 1 кг молока 4-%-й жирности в опытных группах коров были на 7,7–15,2% ниже по сравнению с контролем. По органолептическим и санитарно-гигиеническим показателям молоко, полученное от коров опытных групп, было высшего сорта и отвечало требованиям государственного стандарта на закупаемое молоко. Содержание жира увеличилось на 0,08–0,19%, общего белка – на 0,07–0,15, сухого обезжиренного молочного остатка – на 0,07–0,16, сухого вещества – на 0,15–0,35%. По химическому составу наилучшим оказалось молоко коров, которым скармливали льняной жмых. Примерно одинаковым во всех группах было содержание молочного сахара, золы, кальция, фосфора. Себестоимость 1 ц молока в опытных группах была на 6,3–12,7% ниже, а уровень рентабельности производства молока – на 9,8–16,3% выше по сравнению с контрольными группами

INVESTIGATIONS OF KINETIC CHARACTERISTICS OF SORBENTS BASED ON ZINC OXIDE FOR HIGH TEMPERATURE SYNTH-GAS DESULFURIZATION

In this article simulations were compared with experiments that were run on thermogravimertical analyzer.В данной статье представлено сравнение экспериментов, проведенных на аппарате термогравиметрического анализа (ТГА), с результатами компьютерного моделирования.Исследование выполнено в Уральском федеральном университете за счет гранта Российского научного фонда (проект № 14-19-00524

Core mutations, IL28B polymorphisms and response to peginterferon/ribavirin treatment in Swedish patients with hepatitis C virus genotype 1 infection

<p>Abstract</p> <p>Background</p> <p>Patients infected with hepatitis C virus (HCV) genotype 1 respond poorly to standard treatment with 50% or less achieving sustained virologic response. Predicting outcome is essential and could help avoid unnecessary treatment and reduce health cost. Recently, an association of amino acid substitutions in the core region and treatment outcome was observed in Japanese patients. In the present study, the impact of these mutations on response kinetics and treatment outcome was explored in Caucasian patients.</p> <p>Methods</p> <p>The core region of HCV pre-treatment samples obtained from 50 patients treated with peginterferon/ribavirin in a previous Swedish clinical trial with genotype 1 infection were sequenced. The alleles at rs12979860, a single nucleotide polymorphism (SNP), were assessed in order to identify any co-association with this strong response predictor.</p> <p>Results</p> <p>No association between treatment response and substitutions of core residue 91 was found. In contrast, substitutions of core residue 70 were observed in 6/21 (29%) non-responders, but only in one of 29 responders (p = 0.03), and were more common in subgenotype 1b (R70Q in 6 of 13 strains) than in 1a (R70P in 1 of 37 strains, p = 0.004). The rs12979860 SNP upstream of the IL28B gene was overall the strongest response predictor (p = 0.0001). Core 70 substitutions were associated with poorer response kinetics in patients carrying the CT genotype at rs12979860.</p> <p>Conclusions</p> <p>The results indicate that substitutions of core residue 70 are related to treatment response in Caucasian patients with HCV-1b infection, but are of less importance than IL28B polymorphism.</p