O conhecimento tradicional em sementes crioulas: uma experiência vivenciada na terra indígena Guarita.

Resumos do VIII Congresso Brasileiro de Agroecologia - Porto Alegre/RS - 25 a 28/11/2013

Ranging and phase measurement for LISA

The LISA phase measurement system (PMS) will provide interferometric phase readout of the primary heterodyne signal at microcycle sensitivity, ranging measurements at sub-meter accuracy and data communication at rates of several kilobits per seconds. Our investigations are focused on inter-spacecraft laser ranging and data transfer for LISA using Direct Sequence Spread Spectrum (DS/SS) modulation onto the laser links. We present the setup of an optical experimental to test the levels of performance achievable with a single laser link as well as a new hardware prototype based on FPGA (Field Programmable Gate Array) processing to perform high-accuracy phase readout of the optical signal, ranging measurements, data communication and is suitable for clock noise demodulation and digital laser-phase locking

Photosynthetic pigment levels in Macroptilium lathyroides L under water deficit.

Título em espanhol: Contenido de pigmentos fotosinteticos Macroptilium lathyroides L en condiciones de sequia

Common bean keepers and cultivar diversity at Terra Indigena do Guarita Indian reserve in Brasil.

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Focal amplification of the androgen receptor gene in hormone-naive human prostate cancer.

BACKGROUND: Androgen receptor (AR)-gene amplification, found in 20-30% of castration-resistant prostate cancer (CRPCa) is proposed to develop as a consequence of hormone-deprivation therapy and be a prime cause of treatment failure. Here we investigate AR-gene amplification in cancers before hormone deprivation therapy. METHODS: A tissue microarray (TMA) series of 596 hormone-naive prostate cancers (HNPCas) was screened for chromosome X and AR-gene locus-specific copy number alterations using four-colour fluorescence in situ hybridisation. RESULTS: Both high level gain in chromosome X (≥4 fold; n=4, 0.7%) and locus-specific amplification of the AR-gene (n=6, 1%) were detected at low frequencies in HNPCa TMAs. Fluorescence in situ hybridisation mapping whole sections taken from the original HNPCa specimen blocks demonstrated that AR-gene amplifications exist in small foci of cells (≤ 600 nm, ≤1% of tumour volume). Patients with AR gene-locus-specific copy number gains had poorer prostate cancer-specific survival. CONCLUSION: Small clonal foci of cancer containing high level gain of the androgen receptor (AR)-gene develop before hormone deprivation therapy. Their small size makes detection by TMA inefficient and suggests a higher prevalence than that reported herein. It is hypothesised that a large proportion of AR-amplified CRPCa could pre-date hormone deprivation therapy and that these patients would potentially benefit from early total androgen ablation

Vinte anos de integração pesquisa-extensão-agricultor com feijão no Rio Grande do Sul.

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