Supporting smoking cessation in older patients: a continuing challenge for community nurses

Tobacco smoking continues to pose negative health consequences for smokers and their families, and is the single greatest cause of health inequalities in the UK. Older people are particularly vulnerable to the negative health impacts of smoking and therefore, supporting older smokers to quit remains an important public health goal. Community nurses are required to help patients to lead healthier lifestyles and have ideal opportunities to encourage smoking cessation in older people who are affected by smoking-related health conditions, or whose existing conditions may be exacerbated by continued smoking. This paper discusses how community nurses can support their older patients to quit smoking by fostering a patient-centred partnership through good communication and empathy. The newly developed ‘Very Brief Advice on Smoking’ (VBA) interventions can provide a useful tool for community nurses who experience time constraints to advise older people that psychosocial support with treatment is the most effective method of smoking cessation, while respecting the health decisions of patients

Asynchronous Interaction Aggregation for Action Detection

Understanding interaction is an essential part of video action detection. We propose the Asynchronous Interaction Aggregation network (AIA) that leverages different interactions to boost action detection. There are two key designs in it: one is the Interaction Aggregation structure (IA) adopting a uniform paradigm to model and integrate multiple types of interaction; the other is the Asynchronous Memory Update algorithm (AMU) that enables us to achieve better performance by modeling very long-term interaction dynamically without huge computation cost. We provide empirical evidence to show that our network can gain notable accuracy from the integrative interactions and is easy to train end-to-end. Our method reports the new state-of-the-art performance on AVA dataset, with 3.7 mAP gain (12.6% relative improvement) on validation split comparing to our strong baseline. The results on dataset UCF101-24 and EPIC-Kitchens further illustrate the effectiveness of our approach. Source code will be made public at: https://github.com/MVIG-SJTU/AlphAction

Prenatal and Neonatal Characteristics of Children with Prader-Willi Syndrome

Objective: Prader-Willi syndrome (PWS) is a rare genetic syndrome with a wide spectrum of clinical features in early life. Late diagnoses are still present. We characterized the perinatal and neonatal features of PWS, compared them with those of healthy newborns and assessed the prenatal and neonatal differences between the genetic subtypes. Design: A cohort study in children with PWS. The prevalence of variables was compared with healthy infants (PLUTO cohort) and to population statistics from literature. Patients: 244 infants with PWS and 365 healthy infants. Measurements: Data on prenatal and neonatal variables in both cohorts. Population statistics were collected through an extensive literature search. Results: A higher prevalence of maternal age >35 years was found in PWS compared to healthy infants and population statistics, and the highest maternal age was found in the mUPD group. Higher prevalence of polyhydramnios, caesarean section, labour induction and breech presentation, and lower birth weight SDS was found in PWS compared to healthy infants. High prevalences of decreased fetal movements (78.5%), hypotonia (100%), cryptorchism (95.9%) and poor sucking/tube feeding (93.9%) were found in PWS. Conclusions: This study presents an overview of prenatal and neonatal variables in infants with PWS compared to healthy infants. Our findings may increase clinical awareness of the early perinatal signs of PWS by obstetricians, neonatologists and all those involved in infant care, enabling early diagnosis and start of multidisciplinary treatment

Electric-Field Tuning of Spin-Dependent Exciton-Exciton Interactions in Coupled Quantum Wells

We have shown experimentally that an electric field decreases the energy separation between the two components of a dense spin-polarized exciton gas in a coupled double quantum well, from a maximum splitting of $\sim 4$ meV to zero, at a field of $\sim$35 kV/cm. This decrease, due to the field-induced deformation of the exciton wavefunction, is explained by an existing calculation of the change in the spin-dependent exciton-exciton interaction with the electron-hole separation. However, a new theory that considers the modification of screening with that separation is needed to account for the observed dependence on excitation power of the individual energies of the two exciton components.Comment: 5 pages, 4 eps figures, RevTeX, Physical Review Letters (in press

End-to-End Joint Antenna Selection Strategy and Distributed Compress and Forward Strategy for Relay Channels

Multi-hop relay channels use multiple relay stages, each with multiple relay nodes, to facilitate communication between a source and destination. Previously, distributed space-time codes were proposed to maximize the achievable diversity-multiplexing tradeoff, however, they fail to achieve all the points of the optimal diversity-multiplexing tradeoff. In the presence of a low-rate feedback link from the destination to each relay stage and the source, this paper proposes an end-to-end antenna selection (EEAS) strategy as an alternative to distributed space-time codes. The EEAS strategy uses a subset of antennas of each relay stage for transmission of the source signal to the destination with amplify and forwarding at each relay stage. The subsets are chosen such that they maximize the end-to-end mutual information at the destination. The EEAS strategy achieves the corner points of the optimal diversity-multiplexing tradeoff (corresponding to maximum diversity gain and maximum multiplexing gain) and achieves better diversity gain at intermediate values of multiplexing gain, versus the best known distributed space-time coding strategies. A distributed compress and forward (CF) strategy is also proposed to achieve all points of the optimal diversity-multiplexing tradeoff for a two-hop relay channel with multiple relay nodes.Comment: Accepted for publication in the special issue on cooperative communication in the Eurasip Journal on Wireless Communication and Networkin

P2Y12 blocker monotherapy after percutaneous coronary intervention

For secondary prevention of coronary artery disease (CAD) antiplatelet therapy is essential. For patients undergoing a percutaneous coronary intervention (PCI) temporary dual antiplatelet platelet therapy (DAPT: aspirin combined with a P2Y12 blocker) is mandatory, but leads to more bleeding than single antiplatelet therapy with aspirin. Therefore, to reduce bleeding after a PCI the duration of DAPT is usually kept as short as clinically acceptable; thereafter aspirin monotherapy is administered. Another option to reduce bleeding is to discontinue aspirin at the time of DAPT cessation and thereafter to administer P2Y12 blocker monotherapy. To date, five randomised trials have been published comparing DAPT with P2Y12 blocker monotherapy in 32,181 stented patients. Also two meta-analyses addressing this novel therapy have been presented. P2Y12 blocker monotherapy showed a 50-60% reduction in major bleeding when compared to DAPT without a significant increase in ischaemic outcomes, including stent thrombosis. This survey reviews the findings in the current literature concerning P2Y12 blocker monotherapy after PCI

The star formation history of mass-selected galaxies in the COSMOS field

We explore the evolution of the specific star formation rate (SSFR) for 3.6um-selected galaxies of different M_* in the COSMOS field. The average SFR for sub-sets of these galaxies is estimated with stacked 1.4GHz radio continuum emission. We separately consider the total sample and a subset of galaxies (SF) that shows evidence for substantive recent star formation in the rest-frame optical SED. At 0.2<z<3 both populations show a strong and M_*-independent decrease in their SSFR towards z=0.2, best described by a power- law (1+z)^n, where n~4.3 for all galaxies and n~3.5 for SF sources. The decrease appears to have started at z>2, at least above 4x10^10M_Sun where our conclusions are most robust. We find a tight correlation with power-law dependence, SSFR (M_*)^beta, between SSFR and M_* at all z. It tends to flatten below ~10^10M_Sun if quiescent galaxies are included; if they are excluded a shallow index beta_SFG -0.4 fits the correlation. On average, higher M_* objects always have lower SSFRs, also among SF galaxies. At z>1.5 there is tentative evidence for an upper SSFR-limit that an average galaxy cannot exceed. It is suggested by a flattening of the SSFR-M_* relation (also for SF sources), but affects massive (>10^10M_Sun) galaxies only at the highest z. Below z=1.5 there thus is no direct evidence that galaxies of higher M_* experience a more rapid waning of their SSFR than lower M_* SF systems. In this sense, the data rule out any strong 'downsizing'. We combine our results with recent measurements of the galaxy (stellar) mass function in order to determine the characteristic mass of a SF galaxy (M_*=10^(10.6\pm0.4)M_Sun). In this sense, too, there is no 'downsizing'. Our analysis constitutes the most extensive SFR density determination with a single technique to z=3. Recent Herschel results are consistent with our results, but rely on far smaller samples.Comment: 37 pages, 14 figures, 7 tables; accepted for publication in the Astrophysical Journal; High resolution versions of all figures available at www.mpia-hd.mpg.de/homes/karim/research.htm