Marine-friendly antifouling coating based on the use of a fatty acid derivative as a pigment

This study was devoted to examining the application of copper dodecanoate as a non-contaminant antifouling pigment due to its low copper content and fatty acid nature. For this purpose, antifouling paints with mono-component epoxy resin and rosin matrixes were formulated, and their antifouling efficiency was evaluated. Before its incorporation into the different formulations, the synthesized pigment was characterized. Immersion tests in a marine environment were carried out for 12 months to evaluate the antifouling efficiency of the developed paints; the results were compared with those from a commercial paint. The antifouling efficiency of the new epoxy formulation was found to be considerably higher than that of the rosin formulation and very similar to that of the commercial paint. Most importantly, the release of copper from the epoxy paint formulated with copper dodecanoate was 73.5% lower than that of the commercial paint, suggesting prolonged activity of the developed paint.Peer ReviewedPostprint (published version

α‐Functionalization of imines via visible light photoredox catalysis

The innate electrophilicity of imine building blocks has been exploited in organic synthetic chemistry for decades. Inspired by the resurgence in photocatalysis, imine reactivity has now been redesigned through the generation of unconventional and versatile radical intermediates under mild reaction conditions. While novel photocatalytic approaches have broadened the range and applicability of conventional radical additions to imine acceptors, the possibility to use these imines as latent nucleophiles via single‐electron reduction has also been uncovered. Thus, multiple research programs have converged on this issue, delivering creative and practical strategies to achieve racemic and asymmetric α‐functionalizations of imines under visible light photoredox catalysisThis research was funded by the European Research Council, grant number 647550; the Spanish Government, grant number RTI2018-095038-B-I00; the “Comunidad de Madrid” and European Structural Funds, grant number S2018/NMT-436

Áreas Estanciales. Transformación sustentable del espacio público en la Vía RecreActiva de Zapopan, Jalisco

Las urbes mexicanas carecen de suficientes espacios públicos de calidad para peatones y viandantes no motorizados, pues el modelo nacional de desarrollo ha priorizado la movilidad motorizada en la planeación urbana de las ciudades afectando negativamente la vivencia de la vía pública. En el municipio de Zapopan, Jalisco, los ayuntamientos recientes han desarrollado iniciativas institucionales enfocadas al uso de la bicicleta y a la dignificación del peatón como el Programa Banquetas Libres y la Vía RecreActiva, que opera desde el año 2004 a lo largo de algunas de las vialidades principales de la ciudad. En este Proyecto Profesionalizante de Desarrollo o innovación se plantea una propuesta de Áreas Estanciales para el municipio de Zapopan, que aprovechen los recorridos de la dominical Vía RecreActiva para ofrecer nuevos sitios de descanso y disfrute a los paseantes y usuarios de estas rutas, al tiempo que mejoren la funcionalidad del mobiliario urbano y eleven la calidad de la imagen del espacio público. Las Áreas Estanciales (también conocidas como parques de bolsillo, mini-parques, pocket-parks o parklets) son una tipología de espacios públicos de pequeña escala pensados para que la población transeúnte descanse en un entorno confortable, seguro y vegetado, ganado al viario o a predios desaprovechados. El proyecto desarrolla un modelo físico multifacético de mobiliario urbano que puede ser ubicado en diferentes puntos de la ciudad coincidentes con el recorrido de la Vía RecreActiva Zapopana. Este trabajo aprovechó los principios de la acupuntura verde para el diseño y apropiación del espacio público esperando aportar criterios de intervención urbana-arquitectónica repetibles en otras localidades. Esta propuesta responde directamente a una petición del actual Gobierno Municipal de Zapopan, que permite articular una iniciativa intersectorial Universidad-Sector Público para beneficio de la sociedad.Consejo Nacional de Ciencia y Tecnologí

Multiply Folded Graphene

The folding of paper, hide, and woven fabric has been used for millennia to achieve enhanced articulation, curvature, and visual appeal for intrinsically flat, two-dimensional materials. For graphene, an ideal two-dimensional material, folding may transform it to complex shapes with new and distinct properties. Here, we present experimental results that folded structures in graphene, termed grafold, exist, and their formations can be controlled by introducing anisotropic surface curvature during graphene synthesis or transfer processes. Using pseudopotential-density functional theory calculations, we also show that double folding modifies the electronic band structure of graphene. Furthermore, we demonstrate the intercalation of C60 into the grafolds. Intercalation or functionalization of the chemically reactive folds further expands grafold's mechanical, chemical, optical, and electronic diversity.Comment: 29 pages, 10 figures (accepted in Phys. Rev. B

Evaluation of Aloe Vera Coated Polylactic Acid Scaffolds for Bone Tissue Engineering

3D-printed polylactic acid (PLA) scaffolds have been demonstrated as being a promising tool for the development of tissue-engineered replacements of bone. However, this material lacks a suitable surface chemistry to efficiently interact with extracellular proteins and, consequently, to integrate into the surrounding tissue when implanted in vivo. In this study, aloe vera coatings have been proposed as a strategy to improve the bioaffinity of this type of structures. Aloe vera coatings were applied at three different values of pH (3, 4 and 5), after treating the surface of the PLA scaffolds with oxygen plasma. The surface modification of the material has been assessed through X-ray photoelectron spectroscopy (XPS) analysis and water contact angle measurements. In addition, the evaluation of the enzymatic degradation of the structures showed that the pH of the aloe vera extracts used as coating influences the degradation rate of the PLA-based scaffolds. Finally, the cell metabolic activity of an in vitro culture of human fetal osteoblastic cells on the samples revealed an improvement of this parameter on aloe vera coated samples, especially for those treated at pH 3. Hence, these structures showed potential for being applied for bone tissue regeneration

Cálculo de raciones de mínimo costo para cerdos en zonas tropicales.

Porcicultur

Development and application of asymmetric organocatalytic Mukaiyama and vinylogous Mukaiyama-type reactions

This is the peer reviewed version of the following article: "Development and application of asymmetric organocatalytic Mukaiyama and vinylogous Mukaiyama-type reactions", Chemistry - A European Journal 24.43 (2018): 10906-10933 ,which has been published in final form at https://doi.org/10.1002/chem.201801866. This article may be used for non-commercial purposes in accordance with Wiley terms and conditions for use of self-archived versionsOrganocatalysis is a growing area that is benefiting from advances in many fields. Its implementation has begun in areas such as supramolecular chemistry, organic chemistry and natural product synthesis. While a considerable number of important publications in the field of organocatalytic Mukaiyama-type additions have been reported, they are yet to be fully covered in a review. Therefore, we would like to highlight the applications of various kinds of organocatalysts in Mukaiyama-type reactions, while also including the vinylogous Mukaiyama variation. Herein we describe and discuss the development and current state of the art of the organocatalytic Mukaiyama reaction, vinylogous Mukaiyama and related reactionsFinancial support from the Spanish Government CTQ2015-64561-R (MINECO/FEDER) is gratefully acknowledged. M.F. thanks the UAM for an FPI-UAM fellowshi

Pt(II) coordination complexes as visible light photocatalysts for the oxidation of sulfides using batch and flow processes

A new catalytic system for the photooxidation of sulfides based on Pt(ii) complexes is presented. The catalyst is capable of oxidizing a large number of sulfides containing aryl, alkyl, allyl, benzyl, as well as more complex structures such as heterocycles and methionine amino acid, with complete chemoselectivity. In addition, the first sulfur oxidation in a continuous flow process has been developedJ. A. would also like to thank the MICINN for their ‘Ramón y Cajal’ contract and the European Research Council (ERC-CG, contract number 647550

Living robotic donor nephrectomy. The first case in Latin America

Indexación: Web of Science; Scielo.Introducción: La donación renal en pacientes vivos relacionados es la mejor alternativa de tratamiento para pacientes con insuficiencia renal crónica. La cirugía abierta es el procedimiento de elección; sin embargo, la nefrectomía laparoscópica se ha convertido en una opción viable en centros con experiencia. Con el propósito de disminuír los tiempos de la curva de aprendizaje, algunos centros han introducido la nefrectomía robótica del donante vivo como una opción quirúrgica. Objetivo: Presentar la primera nefrectomía robótica del donante vivo realizada en Latinoamérica. Caso clínico: Paciente de 50 años, esposo, donante vivo relacionado, por afinidad (esposo-esposa). La receptora tiene 54 años con antecedente de insuficiencia renal crónica terminal en espera de ingreso a programa de hemodiálisis. Se realizó nefrectomía robótica izquierda del donante utilizando el sistema robótico da Vinci Si® (Intuitive Surgical, Sunnyvale CA.) mediante abordaje transperitoneal. El tiempo quirúrgico total fue de 188 min, con un sangrado estimado de 300 ml., y un tiempo de isquemia de 6 min. El injerto presentó inicio inmediato de la función. Ambos pacientes fueron dados de alta a las 72 h. Conclusión: La nefrectomía robótica del donante vivo para trasplante es una alternativa segura y factible. Comunicaciones con series con mayor número de pacientes, son necesarias para establecer su definitivo rol.Introduction: Living donor nephrectomy is the best alternative of treatment for patients with chronic renal disease. Even though open surgery remains the gold standard for donor nephrectomy, laparoscopic surgery has become a feasible alternative in referral centers. To minimize the long learning curve associated with this procedure, some centers have introduced robotic donor nephrectomy as a surgical option. Aim: To present the first robotic-assisted laparoscopic donor nephrectomy in Latin America. Clinical case: The donor is a 50 years old male, living-related to the recipient by affinity (husband/wife). The recipient is a 54 years old female with history of end-stage renal disease waiting to initiate dialysis program. A left transperitoneal robotic-assisted laparoscopic nephrectomy employing the da Vinci Si® (Intuitive Surgical, Sunnyvale CA.) is performed. Mean operative time was 188 minutes with an estimated blood loss of 300 ml. Mean ischemia time was 6 minutes. The graft presented immediate function. Both patients were discharged at 72 h. Conclusion: Living donor robotic-assisted laparoscopic nephrectomy is a safe and viable procedure. Larger series are needed to establish its role.http://ref.scielo.org/p438d