Influence of the dimensions of the absorptive capacity in the development of new products in a context of industrial district: an empirical study to the case of the Valencian textile

El presente trabajo integra diversas perspectivas vinculadas a la competitividad empresarial como son la innovación, el territorio y la capacidad de absorción. Hemos pretendido contrastar el efecto de la capacidad de absorción sobre la innovación, dentro de un contexto de distrito industrial, donde el proceso innovador se ve afectado por unas condiciones específicas de acceso, asimilación y explotación de los recursos de conocimiento. Hemos estudiado la población de empresas que forman parte del distrito textil valenciano. Como principales conclusiones observamos que las exterioridades que la empresa recibe en forma de conocimiento, provenientes del entorno en que opera, junto a las habilidades necesarias, en nuestro caso las dimensiones particulares de la capacidad de absorción, benefician el desarrollo de la innovación en la empresaThis research reunites some fundamental aspects for firms’ competitiveness: innovation, territory and absorptive capacity. The objective of this research consists of studying how the absorptive capacity influences the innovation process, centering on the context of an industrial district, where the innovation process is affected by specific access, assimilation and knowledge resource exploitation conditions. We have studying the total population of companies that make up the Valencia textile district. We have found the following main conclusions: The externalities that the company receives in the form of knowledge originating from the environment in which it operates along with the necessary abilities, in our case the particular dimensions of the absorptive capacity, benefit the development of innovation in the compan

Improving SMES competitiveness reinforcing interorganisational networks in industrial clusters

Drawing on a social network approach this paper proposes a methodology that helps with the empowerment and development of interorganisational networks in clusters. Paper emphasizes the necessity of establishing relationships with other firms and external agents in order to empower the creation and diffusion of knowledge, through factors such as innovation. The aim of the proposed methodology is to know how required knowledge should be located and diffused to identify the opportunities motivating the creation of particular interorganisational networks. Similarly, it is also important to know how to determine which agents might to take advantage of these opportunities creating networks

Exposure to secondhand smoke and cognitive impairment in non-smokers: national cross sectional study with cotinine measurement.

addresses: Department of Public Health and Primary Care, University of Cambridge, Cambridge CB2 2SR. [email protected]: PMCID: PMC2643443types: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov'tCopyright © 2009 by the BMJ Publishing Group Ltd. This articles was first published in: BMJ, 2009, Vol. 338, pp. b462 -To examine the association between a biomarker of exposure to secondhand smoke (salivary cotinine concentration) and cognitive impairment

La heterogeneidad dimensional de los distritos industriales. Un estudio longitudinal del caso español

In this paper we study the evolution over the period 1996 to 2007 of the dimensional heterogeneity of the firms located in spanish industrial districts. the results confirm the presence of a district model with an increasingly heterogeneous structure, although higher levels of homogeneity are observed compared to those companies not located in districts. this fact confirms that the district still exerts a significant influence on their companies. On the other hand, this result varies across industrial sectors, presenting fashion‐led districts the higher growth trends of its internal heterogeneityEn el presente trabajo estudiamos la evolución durante el período 1996‐2007 de la hete‐ rogeneidad dimensional de las empresas localizadas en los distritos industriales españoles. Los resultados confirman la presencia de un modelo de distrito con una estructura cada vez más heterogénea, si bien se observan mayores niveles de homogeneidad respecto a las empresas no localizadas en distritos. Este hecho permite confirmar que el distrito todavía ejerce una notable in‐ fluencia sobre sus empresas. Por otro lado, este resultado varía según los diversos sectores, siendo los distritos de las fashion-led industries los que presentan mayores tendencias al crecimiento de su heterogeneidad intern

Loving Outside the Neighborhood: The Conflicting Effects of External Linkages on Incremental Innovation in Clusters

[EN] The present study assesses the explanatory capacity of three levels of factors, namely, internal to the company, and internal and external to the cluster, in predicting firms' incremental innovative performance in cluster contexts. The empirical research conducted here focuses on a sample of 92 companies from the Spanish textile industrial cluster in Valencia. Findings reveal that the signifi- cant role played by firms' interorganizational ties as a moderating factor between absorptive capacity and their incremental innovative performance. Additionally, results reflect the differenti- ated roles developed by intra- and extra-cluster linkages in these interaction processes.Tomas Miquel, JV.; Molina-Morales, FX.; Expósito-Langa, M. (2019). Loving Outside the Neighborhood: The Conflicting Effects of External Linkages on Incremental Innovation in Clusters. Journal of Small Business Management. 57(4):1738-1756. https://doi.org/10.1111/jsbm.12439S17381756574Acs, Z., & Audretsch, D. 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Overcoming undesirable knowledge redundancy in territorial clusters

This work analyzes the existence of redundant knowledge associated to geographic networks of firms. Specifically, our research focuses on how firms can avoid inefficient redundancy ties derived from territorial clusters. We propose that firms embedded in a dense and strong-tie network generate redundant knowledge flows. However, they may use structural dispersion to mediate and overcome this limitation. Our empirical study was conducted drawing on the Spanish ceramic tile industrial cluster to test the potential association between social capital and redundancy. Our findings support the idea that structural dispersion mediates the effects of strong ties and the generation of knowledge redundancy.Molina Morales, FX.; Expósito Langa, M. (2013). Overcoming undesirable knowledge redundancy in territorial clusters. Industry and Innovation. 20(8):739-758. doi:10.1080/13662716.2013.856622S739758208Adger, W. N. (2009). Social Capital, Collective Action, and Adaptation to Climate Change. 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Covalent functionalization of N-doped graphene by N-alkylation

[EN] Nitrogen doped graphene was modified by N-alkylation using a combination of phase transfer catalysis and microwave irradiation. The resulting derivatives of N-doped graphene were analysed showing that the bandgap of the material varied depending on the alkylation agent used.Financial support from MINECO (Spain) (CTQ2013-48252-P and CTQ2012-32315), Junta de Comunidades de Castilla-La Mancha (PEII-2014-014-P) and Generalidad Valenciana (Prometeo 13/19) is gratefully acknowledged. M.B. thanks the MINECO for a doctoral FPI grant.Barrejon, M.; Primo Arnau, AM.; Gomez-Escalonilla, M.; Fierro, JLG.; García Gómez, H.; Langa, F. (2015). Covalent functionalization of N-doped graphene by N-alkylation. Chemical Communications. 51(95):16916-16919. https://doi.org/10.1039/c5cc06285cS16916169195195Wang, H., Maiyalagan, T., & Wang, X. (2012). Review on Recent Progress in Nitrogen-Doped Graphene: Synthesis, Characterization, and Its Potential Applications. ACS Catalysis, 2(5), 781-794. doi:10.1021/cs200652yNavalon, S., Dhakshinamoorthy, A., Alvaro, M., & Garcia, H. (2014). Carbocatalysis by Graphene-Based Materials. Chemical Reviews, 114(12), 6179-6212. doi:10.1021/cr4007347Rodríguez-Pérez, L., Herranz, M. Á., & Martín, N. (2013). The chemistry of pristine graphene. Chemical Communications, 49(36), 3721. doi:10.1039/c3cc38950bWei, D., Liu, Y., Wang, Y., Zhang, H., Huang, L., & Yu, G. (2009). Synthesis of N-Doped Graphene by Chemical Vapor Deposition and Its Electrical Properties. Nano Letters, 9(5), 1752-1758. doi:10.1021/nl803279tLee, W. J., Maiti, U. N., Lee, J. M., Lim, J., Han, T. H., & Kim, S. O. (2014). Nitrogen-doped carbon nanotubes and graphene composite structures for energy and catalytic applications. Chemical Communications, 50(52), 6818. doi:10.1039/c4cc00146jPrimo, A., Atienzar, P., Sanchez, E., Delgado, J. M., & García, H. (2012). From biomass wastes to large-area, high-quality, N-doped graphene: catalyst-free carbonization of chitosan coatings on arbitrary substrates. Chemical Communications, 48(74), 9254. doi:10.1039/c2cc34978gPrimo, A., Sánchez, E., Delgado, J. M., & García, H. (2014). High-yield production of N-doped graphitic platelets by aqueous exfoliation of pyrolyzed chitosan. Carbon, 68, 777-783. doi:10.1016/j.carbon.2013.11.068Wang, X., Sun, G., Routh, P., Kim, D.-H., Huang, W., & Chen, P. (2014). Heteroatom-doped graphene materials: syntheses, properties and applications. Chem. Soc. Rev., 43(20), 7067-7098. doi:10.1039/c4cs00141aWu, M., Cao, C., & Jiang, J. Z. (2010). Light non-metallic atom (B, N, O and F)-doped graphene: a first-principles study. Nanotechnology, 21(50), 505202. doi:10.1088/0957-4484/21/50/505202Rani, P., & Jindal, V. K. (2013). Designing band gap of graphene by B and N dopant atoms. 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Recognizing the hidden : strengthening the HIV surveillance system among key and priority populations in Mozambique

High quality, representative data from HIV surveillance systems that have country ownership and commitment are critical for guiding national HIV responses, especially among key and priority populations given their disproportionate role in the transmission of the virus. Between 2011 to 2013, the Mozambique Ministry of Health has conducted five Biobehavioral Surveillance Surveys among key populations (female sex workers, men who has sex with men and people who inject drugs) and priority populations (long distance truck drives and miners) as part of the national HIV surveillance system. We describe the experience of strengthening the HIV surveillance system among those populations through the implementation of these surveys in Mozambique. We document the lessons learned through the impact on coordination and collaboration; workforce development and institutional capacity building; data use and dissemination; advocacy and policy impact; financial sustainability and community impact. Key lessons learned include the importance of multisectoral collaboration, vital role of data to support key populations visibility and advocacy efforts, and institutional capacity building of government agencies and key populations organizations. Given that traditional surveillance methodologies from routine data often do not capture these hidden populations, it will be important to ensure that Biobehavioral Surveillance Surveys are an integral part of ongoing HIV surveillance activities in Mozambique

Dynamics of Brokerage Positions in Clusters: Evidence from the Spanish Foodstuffs Industry

[EN] Shifting away from traditional approaches orientated towards the analysis of the benefits associated with brokerage, this paper provides valuable insights into the dynamics of this network position and the opportunities to innovate that it provides. Using fine grain micro data collected in a foodstuff Spanish cluster, the evolution of different brokerage profiles is analyzed in depth. It was particularly evident how firm-level characteristics (status, former mediating experience and external openness) and their interactions may generate changes in the different brokerage roles over a period of time. The findings of this work partially validate expectations based on the network dynamics approaches. Status and previous mediating experience facilitate the creation of partnerships, fostering brokerage. Conversely, interaction effects demote brokerage activity at the intra-cluster level, suggesting the selective nature of brokers¿ relational behavior.Financial support from the Spanish Ministry of Economy and Competitiveness (ECO2015-67122-R) is gratefully acknowledged.Belso-Martínez, JA.; Expósito-Langa, M.; Mas-Verdú, F.; Molina-Morales, F. (2017). Dynamics of Brokerage Positions in Clusters: Evidence from the Spanish Foodstuffs Industry. Sustainability. 9(2):1-18. https://doi.org/10.3390/su9020290S1189

Toxicity of the 3,4-methylenedioxymethamphetamine and its enantiomers to Daphnia magna after isolation by semipreparative chromatography

MDMA (3,4-methylenedioxymethamphetamine) is a chiral psychoactive recreational drug sold in illicit markets as racemate. Studies on the impact of MDMA on aquatic organisms are scarce. While enantioselectivity in toxicity in animals and humans has been reported, none is reported on aquatic organisms. This study aimed to investigate the ecotoxicological effects of MDMA and its enantiomers in Daphnia magna. For that, enantiomers (enantiomeric purity > 97%) were separated by liquid chromatography using a homemade semipreparative chiral column. Daphnids were exposed to three concentrations of (R,S)-MDMA (0.1, 1.0 and 10.0 µg L−1) and two concentrations of (R)- and (S)-enantiomers (0.1 and 1.0 µg L−1) over the course of 8 days. Morphophysiological responses were dependent on the substance form and daphnia development stage, and they were overall not affected by the (R)-enantiomer. Changes in swimming behaviour were observed for both the racemate and its enantiomers, but enantioselective effects were not observed. Reproductive or biochemical changes were not observed for enantiomers whereas a significant decrease in acetylcholinesterase and catalase activity was noted at the highest concentration of (R,S)-MDMA (10 µg L−1). Overall, this study showed that sub-chronic exposure to MDMA racemate and its enantiomers can interfere with morphophysiological and swimming behaviour of D. magna. In general, the (R)-enantiomer demonstrated less toxicity than the (S)-enantiomer.This work was financially supported by national funds through the FCT/MCTES (PIDDAC), under the project PTDC/CTA-AMB/6686/2020, and partially supported through the projects UIDB/04423/2020 and UIDP/04423/2020 (Group of Natural Products and Medicinal ChemistryCIIMAR)