53 research outputs found
'There is no heritage in Qatar': Orientalism, colonialism and other problematic histories
This article discusses the construction of Qatari heritage in the context of pre-conceived ideas of ‘cultural heritage’ predominant in the global and regional spheres that operate in this country. It considers the location of Qatar within Middle Eastern heritage discourses and debates, and identifies productive similarities as well as unique avenues for further discussion. The authors identify the challenge of formulating methodologies that are able to recognize, accommodate, encompass and reflect local heritage dialogues and practices that exist in Qatar, which may aid in further researching the wider Arabian Peninsula, its histories and heritages
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Current practices and beliefs regarding supporting dating skills in rehabilitation for Traumatic Brain Injury: A survey study
Background: Relationships are important to quality of life after traumatic brain injury (TBI). However, there has been limited research into how to support dating skills or how professionals view this area.
Method: An online 52-item survey was developed and sent to professionals in the UK involved in rehabilitation after TBI. Recruitment was through professional networks, special interest groups and social media.
Results: 125 participants from a range of professions completed the survey. Many agreed that dating skills are important in rehabilitation (81.6%), but fewer (51.2%) reported engaging in this work. Psychologists, SLTs and OTs were identified as well placed to address dating skills. Case managers also appeared aware of this work. Participants reported using a range of activities to address dating skills, including managing disinhibited behavior and teaching interaction skills. Perceived barriers were both personal and professional, including lack of resources and feeling embarrassed.
Conclusion: This study has highlighted an awareness of the importance of dating in brain injury, but professionals face multiple barriers to supporting dating skills. It is possible to draw on recommendations from related areas, including rehabilitation for cognitive communication difficulties and sexual dysfunction with further research to specifically link these areas to dating skills
The application of precisely controlled functional electrical stimulation to the shoulder, elbow and wrist for upper limb stroke rehabilitation: a feasibility study.
Functional electrical stimulation (FES) during repetitive practice of everyday tasks can facilitate recovery of upper limb function following stroke. Reduction in impairment is strongly associated with how closely FES assists performance, with advanced iterative learning control (ILC) technology providing precise upper-limb assistance. The aim of this study is to investigate the feasibility of extending ILC technology to control FES of three muscle groups in the upper limb to facilitate functional motor recovery post-stroke
Attractor dynamics of elite performance: the high bar longswing
Combining biomechanics and motor control, the aim of this study was to investigate the limit cycle dynamics during the high bar longswing across the UK elite gymnastics pathway age groupings. Senior, junior and development gymnasts (N = 30) performed three sets of eight consecutive longswings on the high bar. The centre of mass motion was examined through Poincaré plots and recurrence quantification analysis exploring the limit cycle dynamics of the longswing. Close to one-dimensional limit cycles were displayed for the senior (correlation dimension (CD) = 1.17 ± .08), junior (CD = 1.26 ± .08) and development gymnasts (CD = 1.33 ± .14). Senior elite gymnasts displayed increased recurrence characteristics in addition to longer longswing duration (p < .01) and lower radial angular velocity of the mass centre (p < .01). All groups of gymnasts had highly recurrent and predictable limit cycle characteristics. The findings of this research support the postulation that the further practice, experience and individual development associated with the senior gymnasts contribute to the refinement of the longswing from a nonlinear dynamics perspective. These findings support the idea of functional task decomposition informing the understanding of skill and influencing coaches’ decisions around skill development and physical preparation
Cellular Active N-Hydroxyurea FEN1 Inhibitors Block Substrate Entry to the Active Site
The structure-specific nuclease human flap endonuclease-1 (hFEN1) plays a key role in DNA replication and repair and may be of interest as an oncology target. We present the first crystal structure of inhibitor-bound hFEN1 and show a cyclic N-hydroxyurea bound in the active site coordinated to two magnesium ions. Three such compounds had similar IC50 values but differed subtly in mode of action. One had comparable affinity for protein and protein– substrate complex and prevented reaction by binding to active site catalytic metal ions, blocking the unpairing of substrate DNA necessary for reaction. Other compounds were more competitive with substrate. Cellular thermal shift data showed engagement of both inhibitor types with hFEN1 in cells with activation of the DNA damage response evident upon treatment. However, cellular EC50s were significantly higher than in vitro inhibition constants and the implications of this for exploitation of hFEN1 as a drug target are discussed
B. Adams & daughter and others
"Mrs B Adams & daughter, and Miss J.K. March Evacuees From Croker [Takako Doki to Edi Endless Summer of Love] Stan Richardson 38th Bn. Ernie & Len Exell Twin Brothers 38th Battalion Harold Exell, Carpenter, Allied Works Council, Katherine & Darwin The Jarvis Brothers 38th Bn."Mrs B Adams & daughter, and Miss J.K. March Evacuees From Croker Island. [Takako Doki to Edi Endless Summer of Love. [Graffito added to quilt whilst on display in library]]. Stan Richardson 38th Battalion. Ernie & Len Exell Twin Brothers 38th Battalion. Harold Exell, Carpenter, Allied Works Council, Katherine & Darwin. The Jarvis Brothers 38th Battalion.Date:199
Camel, blockade and a historical memory perspective: a theme of historical memory portrayed at Qatar National Museum
Camels from ancient times as early as 1200 BC were used as military vehicle and have been associated with the Near East and the Arabian Peninsula. In modern times they remain an important element of Bedouin life and culture (animal protein, dairy products and raw materials, an effective desert vehicle of transport and an indication of wealth). As such, camels are an integral component of heritage and society, essential to the development of Bedouin economies in many regions in the Middle East, North Africa, and Asian regions. Here it is investigated the viability of addressing the topic of the impact on camels by the blockade that has affected Qatar since 5th June 2017 as a theme of historical memory in the Qatari heritage in the National Museum of Qatar (NMoQ). The topic addresses the value and significance of camels in the Qatar peninsula up until the 21st century, and the tragic impact of the blockade on camels and their owners and herders, particularly these which were herding camels across Qatar-Saudi borders. It provides another dimension of history, and archaeology, linked to heritage and society and discusses the way camels have been typically represented in museums in the region due to their cultural significance. Society interviews and media reports are used to support the discussion, which argues for the importance of documenting the historical and culture memory of camels in the new NMoQ.Cămilele din cele mai vechi timpuri încă din 1200 î.Hr. au fost folosite pentru transportul militar și au fost asociate cu Orientul Apropiat și Peninsula Arabică. În timpurile moderne, ele rămân un element important al vieții și culturii beduinilor (proteine animale, produse lactate și materii prime, un vehicul eficient de transport în deșert și un simbol al bogăției). Ca atare, cămilele sunt o componentă integrantă a patrimoniului și a societății, esențiale pentru dezvoltarea economiilor beduine în multe regiuni din Orientul Mijlociu, Africa de Nord și regiunile asiatice. Aici este investigată viabilitatea abordării subiectului legat de impactul asupra cămilelor, cauzat de blocada ce a afectat Qatarul în 5 iunie 2017, ca temă a memoriei istorice a patrimoniului qatarez din Muzeul Național al Qatarului (NMoQ). Subiectul abordează valoarea și semnificația cămilelor din Peninsula Qatar până în secolul 21 și impactul tragic al blocadei asupra cămilelor și a proprietarilor și păstorilor acestora, în special a celor care păstoreau cămile peste granițele Qatarului și ale Arabiei Saudite. Acesta oferă o altă dimensiune a istoriei și arheologiei, legată de patrimoniu și societate și discută modul în care cămilele au fost reprezentate în mod obișnuit în muzeele din regiune datorită semnificației lor culturale. Interviurile sociale și rapoartele mass-media sunt folosite în sprijinul dezbaterii, care argumentează importanța documentării memoriei istorice și culturale a cămilelor în noul NMoQ
Computational models of upper limb motion during functional reaching tasks for application in FES based stroke rehabilitation
Functional electrical stimulation (FES) has been shown to be an effective approach to upper-limb stroke rehabilitation, where it is used to assist arm and shoulder motion. Model-based FES controllers have recently confirmed significant potential to improve accuracy of functional reaching tasks, but they typically require a reference trajectory to track. Few upper-limb FES control schemes embed a computational model of the task; however, this is critical to ensure the controller reinforces the intended movement with high accuracy. This paper derives computational motor control models of functional tasks that can be directly embedded in real-time FES control schemes, removing the need for a predefined reference trajectory. Dynamic models of the electrically stimulated arm are first derived, and constrained optimisation problems are formulated to encapsulate common activities of daily living. These are solved using iterative algorithms, and results are compared with kinematic data from 12 subjects and found to fit closely (mean fitting between 64.6% and 84.0%). The optimisation is performed iteratively using kinematic variables and hence can be transformed into an iterative learning control algorithm by replacing simulation signals with experimental data. The approach is therefore capable of controlling FES in real time to assist tasks in a manner corresponding to unimpaired natural movement. By ensuring that assistance is aligned with voluntary intention, the controller hence maximises the potential effectiveness of future stroke rehabilitation trials
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