112 research outputs found

    Le potentiel touristique du RAVeL en Wallonie

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    * Mise en évidence des rôles touristiques et de loisirs des voies vertes, et compréhension des attentes des utilisateurs quant à celles-ci. * Mise en évidence de tronçons RAVeL pouvant être supports d’activités touristiques par méthodes géomatiques. * Analyse de corrélations entre les fréquentations des RAVeL et ses caractéristiques environnementales : discussion. * Implication : poursuivre la stratégie de développement et la récolte de données statistiques

    Comparison of analytical performances between clot waveform analysis and FibWave in edoxaban-treated patients and healthy controls

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    The activated partial thromboplastin time (aPTT) and the prothrombin time (PT) are widely available coagulation parameters which are however poor predictors of the anticoagulant effect of direct oral anticoagulants (DOACs). Some coagulometers use the clot waveform analysis (CWA) to assess the clotting time but mainly based on a unique parameter. The improvement of these methodologies and the evaluation of the other waveform parameters may increase the sensitivity to DOACs. To assess the performance of an improved clot waveform an method (i.e. FibWave) to detect the impact of edoxaban on the coagulation and the fibrinolytic systems. Seventy-one samples from patients treated with edoxaban collected at minimum concentration (C) and/or maximum concentration (C), and 45 control samples were included. The aPTT- and PT-based CWA as well as the FibIn, FibEx, and FibLysis methodologies of the FibWave were implemented and performed on an ACL-TOP 700. PT and FibEx clotting time were strongly correlated to edoxaban concentration (Pearson  = 0.80 and 0.89, respectively). The FibEx clotting time allowed a better discrimination for samples with 30 and 50 ng/ml of edoxaban compared to PT (cutoffs of 96.5 and 114.2 s for the FibEx versus a unique cutoff of 13.1 s for the PT). The fibrinolytic process was impaired in the presence of edoxaban in a dose-dependent manner. FibEx is more sensitive than aPTT- and PT-based CWA for the detection of the clinically relevant anticoagulant level of edoxaban

    Parietal fibrinous peritonitis in cattle: A literature review

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    peer reviewedBackground: Parietal fibrinous peritonitis (PFP) is a complication of laparotomy in cattle, consisting of fluid and fibrin accumulation within a fibrous capsule between the parietal peritoneum and the abdominal muscles. Since scientific information on PFP is scarce, we aim to collect available information to help practitioners in its diagnosis and treatment, and to formulate research perspectives. Methods: PubMed and GoogleScholar databases were scanned using “cattle” or “bovine”, and one of the following keywords: “seroma”, “parietal fibrinous peritonitis”, “retroperitoneal abscess”, or “wound infection”. Results: Although scientific information is often anecdotal, two recent larger studies shed more light on PFP symptoms, diagnosis and treatment. Symptoms vary according to the cavity’s localisation and size, and include anorexia, weight loss and an inflammatory status. Rectal palpation is strongly indicative, but the definitive diagnosis is made by ultrasound. Trueperella pyogenes and Escherichia coli are frequently isolated germs, although it remains unclear whether they are primary or secondary agents. Good survival rates were reported after surgical drainage. Conclusion: Although the diagnosis and treatment seem clear, the exact pathogenesis of PFP should be the focus of ongoing research. This can be achieved by epidemiological data analysis focusing on risk factors like surgery technique, housing and ration

    How AGN feedback and metal cooling shape cluster entropy profiles

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    Observed clusters of galaxies essentially come in two flavors: non cool core clusters characterized by an isothermal temperature profile and a central entropy floor, and cool-core clusters where temperature and entropy in the central region are increasing with radius. Using cosmological resimulations of a galaxy cluster, we study the evolution of its intracluster medium (ICM) gas properties, and through them we assess the effect of different (sub-grid) modelling of the physical processes at play, namely gas cooling, star formation, feedback from supernovae and active galactic nuclei (AGN). More specifically we show that AGN feedback plays a major role in the pre-heating of the proto-cluster as it prevents a high concentration of mass from collecting in the center of the future galaxy cluster at early times. However, AGN activity during the cluster's later evolution is also required to regulate the mass flow into its core and prevent runaway star formation in the central galaxy. Whereas the energy deposited by supernovae alone is insufficient to prevent an overcooling catastrophe, supernovae are responsible for spreading a large amount of metals at high redshift, enhancing the cooling efficiency of the ICM gas. As the AGN energy release depends on the accretion rate of gas onto its central black hole engine, the AGN responds to this supernova enhanced gas accretion by injecting more energy into the surrounding gas, and as a result increases the amount of early pre-heating. We demonstrate that the interaction between an AGN jet and the ICM gas that regulates the growth of the AGN's BH, can naturally produce cool core clusters if we neglect metals. However, as soon as metals are allowed to contribute to the radiative cooling, only the non cool core solution is produced.Comment: 19 pages, 13 figures, accepted for publication in MNRA

    Antimicrobial Susceptibility Profile of Several Bacteria Species Identified in the Peritoneal Exudate of Cows Affected by Parietal Fibrinous Peritonitis after Caesarean Section

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    peer reviewedAbstract: The aim of this study was to identify the species and antimicrobial susceptibility of bacteria involved in parietal fibrinous peritonitis (PFP).We studied 156 peritoneal fluid samples from cows presenting PFP after caesarean section. Bacteria were cultured in selective media and their antimicrobial susceptibility was tested by disk diffusion assay. Bacteria were isolated in the majority (129/156; 83%) of samples. The majority (82/129; 63%) of positive samples contained one dominant species, while two or more species were cultured in 47/129 (36%) samples. Trueperella pyogenes (T. Pyogenes) (107 strains) was the most identified species, followed by Escherichia coli (E. coli) (38 strains), Proteus mirabilis (P. mirabilis) (6 strains), and Clostridium perfringens (C. perfringens) (6 strains). Several other species were sporadically identified. Antimicrobial susceptibility was tested in 59/185 strains, predominantly E. coli (38 strains) and P. mirabilis (6 strains). Antibiotic resistance, including resistance to molecules of critical importance, was commonly observed; strains were classified as weakly drug resistant (22/59; 37%), multidrug resistant (24/59; 41%), extensively drug resistant (12/59; 20%), or pan-drug resistant (1/59; 2%). In conclusion, extensive antibiotic resistance in the isolated germs might contribute to treatment failure. Ideally, antimicrobial therapy of PFP should be based upon bacterial culture and susceptibility testing

    MoMaF : The Mock Map Facility

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    We present the Mock Map Facility, a powerful tool to generate mock catalogues or images from semi-analytically post-processed snapshots of cosmological N-body simulations. The paper describes in detail an efficient technique to create such mocks from the GALICS semi-analytic model, providing the reader with an accurate quantification of the artifacts it introduces at every step. We show that replication effects introduce a negative bias on the clustering signal -- typically peaking at less than 10 percent around the correlation length. We also thoroughly discuss how the clustering signal is affected by finite volume effects, and show that it vanishes at scales larger than about a tenth of the simulation box size. For the purpose of analysing our method, we show that number counts and redshift distributions obtained with GALICS and MOMAF compare well to K-band observations and to the 2dFGRS. Given finite volume effects, we also show that the model can reproduce the APM angular correlation function. The MOMAF results discussed here are made publicly available to the astronomical community through a public database. Moreover, a user-friendly Web interface (http://galics.iap.fr) allows any user to recover her/his own favourite galaxy samples through simple SQL queries. The flexibility of this tool should permit a variety of uses ranging from extensive comparisons between real observations and those predicted by hierarchical models of galaxy formation, to the preparation of observing strategies for deep surveys and tests of data processing pipelines.Comment: 19 pages, 15 Figs, significantly modified version now accepted for publication in MNRAS. High-resolution version available at http://galics.cosmologie.fr/papers/momaf.ps.g
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