Orthodontic treatment as triggering factor of medication related osteonecrosis of the jaw in a breast cancer patient. Report of a rare case

Orthodontic treatment in adult patient is widely accepted nowadays. Therefore, orthodontists are needed to interact with more complex medical histories that may interfere with the orthodontic treatment. Antiresorptive medication is a widely used treatmen

Venous thromboembolism after oral and maxillofacial oncologic surgery : report and analysis of 14 cases in Chinese population

Venous thromboembolism (VTE) including deep vein thrombosis (DVT) and pulmonary embolism (PE) is a leading cause of death in cancer patients. The aim of this study was to explore the potential risk factor of VTE in oral and maxillofacial oncological surgery. The data of patients who received operation in our institution were gathered in this retrospective study. A diagnosis of VTE was screened and confirmed by computer tomography angiography (CTA) of pulmonary artery or ultrasonography examination of lower extremity. Medical history and all perioperative details were analyzed. 14 patients were diagnosed as VTE, including 6 cases of PE, 7 cases of DVT, 1case of DVT and PE. The mean age of these patients was 62.07 years. Reconstruction was performed in 12 patients of these cases, most of which were diagnosed as malignance. Mean length of surgery was 8.74 hours, and lower extremity deep venous cannula (DVC) was performed in all these patients. We analyzed several characters of oral and maxillofacial surgery and suggested pay attention to lower extremity DVC which had a high correlation with DVT according to our data

Comparative biomechanical evaluation of three diamensional (3D) miniplates with classic osteosynthesis systems in mandibular angle fractures

Introduction: Therapy of mandibular angle fractures is controversial and is still a subject of continuous interest in international literature. Three dimensional (3D) mini plates are relatively new, with no biomechanical or clinical studies to support their use. The aim of this study is to comparatively evaluate the use of two 3D mini plating systems for the treatment of mandibular angle fractures, with mini plates used in ordinary clinical practice. Materials and Methods: Synthetic mandible replicas were used to evaluate the effectiveness of the 3D plates along with four other mandibular angle plating techniques. The plating techniques consisted of: 1. A 3D miniplate (2x2 holes, square, 2mm), 2. A 3D miniplate (6x2 holes, curved, 2mm), 3. Two plate system (four hole, straight, 2mm, placed at the lateral oblique ridge and 1,6mm), 4. One single miniplate (four hole, straight, 2mm), 5. Two plate system (four hole, straight, 2mm, placed in the buccal aspect of the lateral oblique ridge and 1,6mm), 6. A fracture plate (six hole, curved). Each group was subjected to incisal and homolateral molar region loading by a tensile materials testing machine (Monsanto Tensometer 20). Load stiffness values and peak measurements of the fracture gap distraction at the superior aspect of the mandible were measured. The mean values (± standard deviation) were derived and compared using students t-test, with statistical significance set at p<0.05. Results: For homolateral molar loading, statistically significant differences existed within groups (P<0.05). For incisal edge loading, no statistically significant differences were found for stiffness among the fixation methods tested. Gap distraction at the superior aspect of the mandible was limited for four of the groups tested. Conclusion: Under the conditions tested the 3D square plate system provided the most favourable mechanical behaviour.Εισαγωγή: H θεραπεία των καταγμάτων της γωνίας της κάτω γνάθου είναι αμφιλεγόμενη και παραμένει ένα θέμα διαρκούς αντιπαράθεσης στη διεθνή βιβλιογραφία. Οι τρισδιάστατες μίνι πλάκες (3D) είναι σχετικά καινούργιες και υποστηρίζεται ότι εμφανίζουν βελτιωμένη μηχανική συμπεριφορά, χωρίς όμως να υπάρχουν βιβλιογραφικά δεδομένα ή κλινικές έρευνες που να υποστηρίζουν τη χρήση τους. Σκοπός της μελέτης αυτής είναι να αξιολογηθούν δύο τρισδιάστατα μίνι συστήματα οστεοσύνθεσης και να συγκριθούν με αντίστοιχα κλασικά συστήματα μίνι πλακών που χρησιμοποιούνται ευρέως στην κλινική πράξη. Υλικό-Μέθοδος: Συνθετικές κάτω γνάθοι χρησιμοποιήθηκαν για την αξιολόγηση των τρισδιάστατων συστημάτων οστεοσύνθεσης, σε σύγκριση με τέσσερα ακόμα συστήματα. Οι ομάδες μελέτης ήταν οι εξής: Ομάδα 1. Mία 3D μίνι πλάκα 2χ2 οπές, τετράγωνη 2.0mm, Ομάδα 2. Mία 3D μίνι πλάκα 4χ2 οπές, ορθογώνια, 2.0mm, Ομάδα 3. Σύστημα δύο πλακών, 4 οπές , ευθείες, 2.0mm & 1.6mm, Ομάδα 4. Mία μίνι πλάκα, 4 οπές, ευθεία με διάστημα, 2.0mm, Ομάδα 5. Σύστημα δύο πλακών, 4 οπές, ευθείες, 2.0mm & 1.6mm, Ομάδα 6. Μία πλάκα κατάγματος (fracture plate) 6 οπές, γωνία 140°, 2.0mm. Κάθε ομάδα υποβλήθηκε σε φόρτιση στην πρόσθια τομική περιοχή και στην σύστοιχη με το κάταγμα γομφιακή περιοχή, μέσω ενός μηχανήματος εφαρμογής τάσης (Monsanto Tensometer 20). Έγινε μέτρηση και καταγραφή του κενού στο άνω όριο του κατάγματος καθώς επίσης και μετρήσεις τιμών ακαμψίας (stiffness) για κάθε τύπο φόρτισης ξεχωριστά. Υπολογίστηκαν οι μέσες τιμές και οι σταθερές αποκλίσεις των παραπάνω τιμών και ακολούθως έγινε στατιστική ανάλυση των αποτελεσμάτων με χρήση του απλού t-test. Στατιστικά σημαντικά θεωρήθηκαν αποτελέσματα με p<0,05%. Αποτελέσματα: Κατά τη φόρτιση της ομόπλευρης προς το κάταγμα γομφιακής περιοχής η στατιστική ανάλυση ανέδειξε στατιστικά σημαντικές διαφορές μεταξύ των ομάδων. Κατά τη φόρτιση της πρόσθιας τομικής περιοχής δεν αναδείχθηκαν στατιστικά σημαντικές διαφορές. Το κενό στο άνω χείλος του κατάγματος ήταν οριακό σε τέσσερα από τα συστήματα που εξετάστηκαν. Συμπεράσματα: Με βάση το πειραματικό μοντέλο που χρησιμοποιήθηκε η ομάδα 1 (τετράγωνη 3D) εμφάνισε την καλύτερη εμβιομηχανική συμπεριφορά

Chondrosarcoma of the mandibular condyle in a patient with Werner syndrome: A case report

Werner syndrome, also called progeria of the adult and pangeria is a rare autosomal recessive disorder that affects connective tissue throughout the body. It is associated with premature ageing and an increased risk of cancer and other diseases. The mean survival for patients with Werner syndrome is 47 years. Death usually occurs when patients are aged 30-65 years because of atherosclerosis or malignant tumours. The purpose of this paper is to present a patient with Werner syndrome exhibiting a chondrosarcoma of the left temporomandibular joint and ramus. To the best of our knowledge this is the first case, of a Werner syndrome patient with an associated head and neck chondrosarcoma being reported. The diagnostic procedure followed and management of the patient are outlined in the paper as well. (C) 2012 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved

Venous thromboembolism after oral and maxillofacial oncologic surgery: Report and analysis of 14 cases in Chinese population

Background: Venous thromboembolism (VTE) including deep vein thrombosis (DVT) and pulmonary embolism (PE) is a leading cause of death in cancer patients. The aim of this study was to explore the potential risk factor of VTE in oral and maxillofacial oncological surgery. Material and Methods: The data of patients who received operation in our institution were gathered in this retrospective study. A diagnosis of VTE was screened and confirmed by computer tomography angiography (CTA) of pulmonary artery or ultrasonography examination of lower extremity. Medical history and all perioperative details were analyzed. Results: 14 patients were diagnosed as VTE, including 6 cases of PE, 7 cases of DVT, 1case of DVT and PE. The mean age of these patients was 62.07 years. Reconstruction was performed in 12 patients of these cases, most of which were diagnosed as malignance. Mean length of surgery was 8.74 hours, and lower extremity deep venous cannula (DVC) was performed in all these patients. Conclusions: We analyzed several characters of oral and maxillofacial surgery and suggested pay attention to lower extremity DVC which had a high correlation with DVT according to our data