Temporal Evolution of the Migration-related Topics on Social Media?

This poster focuses on capturing the temporal evolution of migration-related topics on relevant tweets. It uses Dynamic Embedded Topic Model (DETM) as a learning algorithm to perform a quantitative and qualitative analysis of these emerging topics. TweetsKB is extended with the extracted Twitter dataset along with the results of DETM which considers temporality. These results are then further analyzed and visualized. It reveals that the trajectories of the migration-related topics are in agreement with historical events

Efecto de la competencia de malezas y la densidad de siembra sobre dos cultivares de sorgo granífero (Sorghum bicor)

Se analizó la respuesta de dos cultivares ACA 550 y MS 3 Morgan de sorgo granifero (Sorghum bicolor), sembrados en dos densidades (115.400 y 192.300 plantas/ha), frente a la competencia de malezas. A los 21 y42díasde la emergencia del cultivo se calcularon índices de agresividad en base a la materia seca aérea del cultivo y maleza en mutua competencia y sin competencia. Estos datos demostraron que el cv. ACA 550 fue más competitivo que el MS 3 Morgan, ello independientemente de la densidad de siembra. Sin embargo, esa característica inicial de mayor competitividad del cv ACA 550 no se manifestó en términos de rendimiento de grano, donde las diferencias entre ambos híbridos resultaron no significativas (p = 0,05) y con una ligera tendencia a mayor producción por parte del cv. MS 3 Morgan. La competencia de malezas, principalmente gramíneas, provocó una pérdida de rendimiento de grano del 91,1%, debida principalmente a la disminución del número de panojas y en menor medida al tamaño de las mismas. Sobre esa producción no tuvo efecto alguno la densidad de siembra. No pudo comprobarse la hipótesis de diferencias en las habilidades competitivas de los dos cultivares en la variable rendimiento de grano. Se asume que diferencias de comportamiento entre híbridos y densidades de siembra podrían ocurrir en niveles de infestación de malezas mucho menores a los considerados en este experimento

Revista de libros

Se reseñan los siguientes libros: - Osvaldo F. A. Menghin: Origen y desarrollo racial de la especie humana. Editorial Nova; sección “Compendios de iniciación cultural”, Buenos Aires, 1958. Vol. rústica, 99 págs., incluso selección bibliográfica y 10 láminas fuera de texto (reproducción en blanco y negro). - Lorenzo Luzuriaga: La Institución Libre de Enseñanza. Edición del Departamento editorial de la Universidad de Buenos Aires. Buenos Aires, 1957, 228 páginas. - Luis Reissig: La era tecnológica y la educación. Editorial Losada, Buenos Aires, 1958, Vol. rústica, 98 páginas. - Emilio Farré: Cincuenta años de filosofía en Argentina. Editorial Peüser, Buenos Aires, 1958. Vol. encuadernado, 362 páginas. - Paúl Westheim: Ideas fundamentales del arte prehispánico en México. Editorial Fondo de Cultura Económica, México, 1957. Volumen encuadernado e ilustrado, 285 páginas.Universidad Nacional de La Plat

Using Semantic Web technologies in the development of data warehouses: A systematic mapping

The exploration and use of Semantic Web technologies have attracted considerable attention from researchers examining data warehouse (DW) development. However, the impact of this research and the maturity level of its results are still unclear. The objective of this study is to examine recently published research articles that take into account the use of Semantic Web technologies in the DW arena with the intention of summarizing their results, classifying their contributions to the field according to publication type, evaluating the maturity level of the results, and identifying future research challenges. Three main conclusions were derived from this study: (a) there is a major technological gap that inhibits the wide adoption of Semantic Web technologies in the business domain;(b) there is limited evidence that the results of the analyzed studies are applicable and transferable to industrial use; and (c) interest in researching the relationship between DWs and Semantic Web has decreased because new paradigms, such as linked open data, have attracted the interest of researchers.This study was supported by the Universidad de La Frontera, Chile, PROY. DI15-0020. Universidad de la Frontera, Chile, Grant Numbers: DI15-0020 and DI17-0043

Revista de libros

Se reseñan los siguientes libros: - Osvaldo F. A. Menghin: Origen y desarrollo racial de la especie humana. Editorial Nova; sección “Compendios de iniciación cultural”, Buenos Aires, 1958. Vol. rústica, 99 págs., incluso selección bibliográfica y 10 láminas fuera de texto (reproducción en blanco y negro). - Lorenzo Luzuriaga: La Institución Libre de Enseñanza. Edición del Departamento editorial de la Universidad de Buenos Aires. Buenos Aires, 1957, 228 páginas. - Luis Reissig: La era tecnológica y la educación. Editorial Losada, Buenos Aires, 1958, Vol. rústica, 98 páginas. - Emilio Farré: Cincuenta años de filosofía en Argentina. Editorial Peüser, Buenos Aires, 1958. Vol. encuadernado, 362 páginas. - Paúl Westheim: Ideas fundamentales del arte prehispánico en México. Editorial Fondo de Cultura Económica, México, 1957. Volumen encuadernado e ilustrado, 285 páginas.Universidad Nacional de La Plat

Interaction of Cu-dipeptide complexes with Calf Thymus DNA and antiproliferative activity of [Cu(ala-phe)] in osteosarcoma-derived cells

In this work the study of Calf Thymus DNA interaction with several Cu(l-dipeptide) complexes was reported. The binding stoichiometry (Cu(mmol)/DNAmol base) was determined and in an attempt to clarify the binding mode, EPR and CD experiments were performed. All the studied complexes interacted with DNA, in a more selective way than [Cu(H2O)6]2+, being the [Cu(ala-phe)] the complex with the highest interaction. The EPR experiments suggested that the monomeric species formed in solution were coordinated through a nitrogen atom of the DNA bases (inner-sphere binding) and the CD studies showed structural changes upon the DNA–complex interaction. Besides, the ratio Cu(mmol)/DNAmol base obtained by the binding stoichiometry experiments was close to that found by EPR and CD determinations. The effect on cell proliferation determined by the crystal violet bioassay on UMR106 rat osteosarcoma-derived cells showed that the [Cu(ala-phe)] complex exerted an antiproliferative action against this tumor linePEDECIBA Química (Uruguayan organisations)CNPqCONICETUNLPConsejo Superior de Investigaciones Científicas (CSIC

Enfoque del tratamiento de la Salud Mental en los últimos 70 años en Bs As, Argentina

Objetivos: evaluar el impacto terapéutico y costos asociados a tratamientos de patología mental en los últimos 70 años. Metodología: estudio retrospectivo-descriptivo con etapa analítica en el cual se evaluaron historias clínicas de pacientes internados en Institución de Salud Mental de Buenos Aires. Las variables analizadas fueron: edad, sexo, motivo de internación, promedio de estadía, re-internaciones, número y tipo de medicamentos por década, resultados en términos de mejoría clínica, costo de medicamentos e internaciones en cada década

Metallic ions as therapeutic agents in tissue engineering scaffolds: an overview of their biological applications and strategies for new developments

This article provides an overview on the application of metallic ions in the fields of regenerative medicine and tissue engineering, focusing on their therapeutic applications and the need to design strategies for controlling the release of loaded ions from biomaterial scaffolds. A detailed summary of relevant metallic ions with potential use in tissue engineering approaches is presented. Remaining challenges in the field and directions for future research efforts with focus on the key variables needed to be taken into account when considering the controlled release of metallic ions in tissue engineering therapeutics are also highlighted

Other-Sex Friendships in Late Adolescence: Risky Associations for Substance Use and Sexual Debut?

Adolescents’ friendships with other-sex peers serve important developmental functions, but they may also facilitate engagement in problem behavior. This study examines the unique contributions of other-sex friendships and friends’ behavior to alcohol use, smoking, and initiation of sexual intercourse among late adolescent girls and boys. A total of 320 adolescents (53% girls; 33% racial/ethnic minorities) provided sociometric nominations of friendships annually in grades 10–12. Friendship networks were derived using social network analysis in each grade. Adolescents and their friends also reported on their alcohol use, smoking, and sexual debut at each assessment. After controlling for demographics, previous problem behavior, and friends’ behavior, other-sex friendships in 10th grade were associated with initiation of smoking among girls over the following year, and other-sex friendships in 11th grade were linked with lower levels of subsequent alcohol use among boys. Additionally, friends’ smoking and sexual experience in 10th grade predicted the same behaviors for all adolescents over the following year. Other-sex friendships thus appear to serve as a risk context for adolescent girls’ smoking and a protective context for adolescent boys’ drinking. Promoting mixed-gender activities and friendships among older high school students may be helpful in reducing males’ alcohol use, but may need to incorporate additional components to prevent increases in females’ smoking

DNA methylation in glioblastoma: impact on gene expression and clinical outcome

International audienceBACKGROUND: Changes in promoter DNA methylation pattern of genes involved in key biological pathways have been reported in glioblastoma. Genome-wide assessments of DNA methylation levels are now required to decipher the epigenetic events involved in the aggressive phenotype of glioblastoma, and to guide new treatment strategies. RESULTS: We performed a whole-genome integrative analysis of methylation and gene expression profiles in 40 newly diagnosed glioblastoma patients. We also screened for associations between the level of methylation of CpG sites and overall survival in a cohort of 50 patients uniformly treated by surgery, radiotherapy and chemotherapy with concomitant and adjuvant temozolomide (STUPP protocol). The methylation analysis identified 616 CpG sites differentially methylated between glioblastoma and control brain, a quarter of which was differentially expressed in a concordant way. Thirteen of the genes with concordant CpG sites displayed an inverse correlation between promoter methylation and expression level in glioblastomas: B3GNT5, FABP7, ZNF217, BST2, OAS1, SLC13A5, GSTM5, ME1, UBXD3, TSPYL5, FAAH, C7orf13, and C3orf14. Survival analysis identified six CpG sites associated with overall survival. SOX10 promoter methylation status (two CpG sites) stratified patients similarly to MGMT status, but with a higher Area Under the Curve (0.78 vs. 0.71, p-value < 5e-04). The methylation status of the FNDC3B, TBX3, DGKI, and FSD1 promoters identified patients with MGMT-methylated tumors that did not respond to STUPP treatment (p-value < 1e-04). CONCLUSIONS: This study provides the first genome-wide integrative analysis of DNA methylation and gene expression profiles obtained from the same GBM cohort. We also present a methylome-based survival analysis for one of the largest uniformly treated GBM cohort ever studied, for more than 27,000 CpG sites. We have identified genes whose expression may be tightly regulated by epigenetic mechanisms and markers that may guide treatment decisions