449 research outputs found

    The impact of leadership culture on employer value proposition

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    As a management-theoretical concept, leadership culture can be understood as distinct leadership behavior that constitutes organizational culture. The purpose of this thesis is to examine how leadership culture can contribute to organizations’ employer value proposition through an enhancement of employer attractiveness. An empirical study was conducted based on mediation hypotheses. The research revealed that leadership culture is a strong predictor for employer attractiveness, and the relationship is mediated by the value propositions of developmental and interest value. These refer to the employees’ perceived possibilities to promote their career and the incorporation of excitement and creativity into their work(see Berthon, Ewing & Hah 2005)

    Lagrangian Mechanics and the Motion of a T-Handle

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    This paper begins by deriving the equations of motion for the Lagrangian formulation of mechanics. Lagrangian mechanics describes the same thing as the traditional Newtonian mechanics (which is what is taught in most undergrad physics classes), but rather than model the system through forces, it models the system through energy. Energy is conserved in a system, which allows the Lagrangian formulation to model certain types of systems in a more efficient way than the Newtonian formulation. Next, the paper explores rigid body motion, specifically looking at the motion of the angular momentum. The goal of this part is to explain what causes an object to flip back and forth when it is rotating about one of its axes in zero gravity. To help demonstrate why this happens, there is a specific example of a t-handle exhibiting such motion. The t-handle in this paper is simply two cylinders, one resting horizontally atop the other, forming a sort of \u27T\u27 shape This example reveals that changing the dimensions of the t-handle will change how the body moves as it rotates about specific axes

    Modulation of the c-Jun N-terminal kinase activity in the embryonic heart in response to anoxia-reoxygenation: involvement of the Ca2+ and mitoKATP channels

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    Whether the response of the fetal heart to ischemia-reperfusion is associated with activation of the c-Jun N-terminal kinase (JNK) pathway is not known. In contrast, involvement of the sarcolemmal L-type Ca2+ channel (LCC) and the mitochondrial KATP (mitoKATP) channel has been established. This work aimed at investigating the profile of JNK activity during anoxia-reoxygenation and its modulation by LCC and mitoKATP channel. Hearts isolated from 4-day-old chick embryos were submitted to anoxia (30min) and reoxygenation (60min). Using the kinase assay method, the profile of JNK activity in the ventricle was determined every 10min throughout anoxia-reoxygenation. Effects on JNK activity of the LCC blocker verapamil (10nM), the mitoKATP channel opener diazoxide (50μM) and the blocker 5-hydroxydecanoate (5-HD, 500μM), the mitochondrial Ca2+ uniporter (MCU) inhibitor Ru360 (10μM), and the antioxidant N-(2-mercaptopropionyl) glycine (MPG, 1mM) were determined. In untreated hearts, JNK activity was increased by 40% during anoxia and peaked fivefold relative to basal level after 30-40min reoxygenation. This peak value was reduced by half by diazoxide and was tripled by 5-HD. Furthermore, the 5-HD-mediated stimulation of JNK activity during reoxygenation was abolished by diazoxide, verapamil or Ru360. MPG had no effect on JNK activity, whatever the conditions. None of the tested pharmacological agents altered JNK activity under basal normoxic conditions. Thus, in the embryonic heart, JNK activity exhibits a characteristic pattern during anoxia and reoxygenation and the respective open-state of LCC, MCU and mitoKATP channel can be a major determinant of JNK activity in a ROS-independent manne

    Using Phosphorus Recovery from Wastewater as a Context for Teaching Sustainable Development with USEPA P3 Support

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    Phosphorus is an essential element required for agriculture. Current practices include one-way use of phosphorus: that is mining; production of fertilizer; land application; and ultimately loss to aquatic sediments. Once in the aquatic environment, phosphorus stimulates eutrophication resulting in the death of water bodies. With financial support from a People, Prosperity, and Planet program grant of the U.S. Environmental Protection Agency, an interdisciplinary team of faculty at the University of Cincinnati used phosphorus recovery from sewage and re-utilization as a struvite fertilizer as the context for a year-long course of study integrating graduate and undergraduate students in Environmental Engineering and Science as well as Environmental Studies. This presentation will highlight the original course format, results of student assessment from the 2004-2005 academic year, modifications incorporated for the 2005-2006 academic year, and the subsequent findings of student perceptions and learning. The challenge of integrating across two colleges within a comprehensive university system will be discussed, and our approaches for meeting the learning needs and course expectations of a diverse student population will be included

    Procalcitonin decrease over 72 hours in US critical care units predicts fatal outcome in sepsis patients

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    Introduction: Close monitoring and repeated risk assessment of sepsis patients in the intensive care unit (ICU) is important for decisions regarding care intensification or early discharge to the ward. We studied whether considering plasma kinetics of procalcitonin, a biomarker of systemic bacterial infection, over the first 72 critical care hours improved mortality prognostication of septic patients from two US settings. Methods: This retrospective analysis included consecutively treated eligible adults with a diagnosis of sepsis from critical care units in two independent institutions in Clearwater, FL and Chicago, IL. Cohorts were used for derivation or validation to study the association between procalcitonin change over the first 72 critical care hours and mortality. Results: ICU/in-hospital mortality rates were 29.2%/31.8% in the derivation cohort (n = 154) and 17.6%/29.4% in the validation cohort (n = 102). In logistic regression analysis of both cohorts, procalcitonin change was strongly associated with ICU and in-hospital mortality independent of clinical risk scores (Acute Physiology, Age and Chronic Health Evaluation IV or Simplified Acute Physiology Score II), with area under the curve (AUC) from 0.67 to 0.71. When procalcitonin decreased by at least 80%, the negative predictive value for ICU/in-hospital mortality was 90%/90% in the derivation cohort, and 91%/79% in the validation cohort. When procalcitonin showed no decrease or increased, the respective positive predictive values were 48%/48% and 36%/52%. Discussion In septic patients, procalcitonin kinetics over the first 72 critical care hours provide prognostic information beyond that available from clinical risk scores. If these observations are confirmed, procalcitonin monitoring may assist physician decision-making regarding care intensification or early transfer from the ICU to the floor

    Detection of intensification of the global water cycle: the potential role of FRIEND

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    Diagnostic studies of 14-year, 2 — 2°, Variable Infiltration Capacity (VIC) model off-line simulations of the global terrestrial water budget suggest that, given the annual variability in the major components of continental hydrological cycles (precipitation, evaporation, and runoff), several decades to perhaps centuries of measurements may be needed to detect with high confidence the intensification predicted by recent global climate model (GCM) studies simulating plausible global warming scenarios. Furthermore, these measurements may need to originate from a wider geographic expanse than is currently investigated within large-scale hydrological assessment programmes, such as the Global Energy and Water Experiment (GEWEX). Smaller, geographically dispersed basins, including many of those participating in the International Flow Regimes from International Experimental and Network Data (FRIEND) programme, could therefore play important roles in detection of an intensification in the global water cycle

    Quantum-noise--randomized data-encryption for WDM fiber-optic networks

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    We demonstrate high-rate randomized data-encryption through optical fibers using the inherent quantum-measurement noise of coherent states of light. Specifically, we demonstrate 650Mbps data encryption through a 10Gbps data-bearing, in-line amplified 200km-long line. In our protocol, legitimate users (who share a short secret-key) communicate using an M-ry signal set while an attacker (who does not share the secret key) is forced to contend with the fundamental and irreducible quantum-measurement noise of coherent states. Implementations of our protocol using both polarization-encoded signal sets as well as polarization-insensitive phase-keyed signal sets are experimentally and theoretically evaluated. Different from the performance criteria for the cryptographic objective of key generation (quantum key-generation), one possible set of performance criteria for the cryptographic objective of data encryption is established and carefully considered.Comment: Version 2: Some errors have been corrected and arguments refined. To appear in Physical Review A. Version 3: Minor corrections to version

    HUBUNGAN PENINGKATAN BERAT BADAN FE4NGAN KONVERSI SPUTUM PADA PASIEN TUBERKULOSIS DI RSUDZA BANDA ACEH

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    ABSTRAKKonversi sputum pada fase awal pengobatan merupakan salah satu indikator awal keberhasilan terapi obat anti tuberkulosis (OAT). Nutrisi merupakan faktor penting yang juga mempengaruhi kesembuhan pasien tuberkulosis Penelitian ini bertujuan untuk mengetahui hubungan peningkatan berat badan dengan konversi sputum setelah fase awal pada pasien TB di Rumah Sakit Umum dr. Zainoel Abidin Banda Aceh (RSUDZA). Jenis penelitian yang digunakan adalah Cross sectional. Subjek penelitian terdiri atas 92 pasien tuberkulosis di poliklinik DOTS RSUDZA Banda Aceh yang diperoleh dengan metode total sampling terhitung dari Januari sampai dengan Desember 2013. Hasil penelitian dianalisis menggunakan uji statistik Fisher dengan Confident interval 95%. Hasil uji statistik menunjukkan p = 0,107 (p > 0,05) yang menunjukkan bahwa tidak ada hubungan antara peningkatan berat badan dengan konversi sputum pada penderita tuberkulosis yang telah mendapatkan OAT fase awal. Diharapkan adanya penelitian yang lebih lanjut mengenai hubungan nutrisi dengan konversi sputum dengan jumlah sampel yang lebih besar dan desain penelitian yang lebih baik. Kata Kunci : Tuberkulosis, Konversi sputum, Berat badan ABSTRACTSputum conversion at the initial phase of treatment is one of the early indicators of the success of anti-tuberculosis drug therapy (OAT). Nutrition is an important factor that also effects the recovery of tuberculosis patients The aim of this study was to determine the relationship of weight gain and sputum conversion after the initial phase of TB patients at the General Hospital dr. Zainoel Abidin Banda Aceh (RSUDZA). This research was cross sectional study. Subjects consisted of 92 outpatient DOTS tuberculosis in RSUDZA Banda Aceh obtained with total sampling method starting from January to December 2013. Results were analyzed using Fisher test with 95% confident interval. Statistical test results p= 0,107 (p > 0,05) that showed there is no association between increased weight to conversion of sputum in patients with tuberculosis who have earned OAT initial phase, It is expected that the presence of further reaserh on the relationship of nutrition with sputum convertion with a larger number of sampel and design better research. Keywords: Tuberculosis, Sputum conversion, Weight los
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