Influence of recirculation rate on the performance of a combined anaerobic-aerobic reactor applied to the removal of carbon and nitrogen from poultry slaughterhouse wastewater

The objective of this study was to evaluate a combined anaerobic-aerobic upflow fixed-bed reactor with liquid phase recirculation for the removal of nitrogen and organic matter from poultry slaughterhouse wastewater. The reactor performance was evaluated with a hydraulic retention time (HRT) of 11 h and three different recirculation rates (R=0.5; 1 and 2). The highest nitrogen removal efficiency value was obtained with an HRT of 11 h (6.8 h in the anaerobic zone and 4.2 h in the aerobic zone) and a recirculation rate of 2. In this condition, the total nitrogen removal efficiency was 69%,  with effluent concentrations of 6 mg NH4+ L-1 and 12 mg NO3- L-1. For all tested conditions, there was good chemical oxygen demand (COD) removal, with efficiency above 95%. The effect of dilution and the favoring of mass transfer caused by the increase in the recirculation rate positively influenced reactor performance.Key words: Anaerobic degradation, nitrification, denitrification, combined reactor

A terrestrial planet candidate in a temperate orbit around Proxima Centauri

At a distance of 1.295 parsecs, the red dwarf Proxima Centauri (α Centauri C, GL 551, HIP 70890 or simply Proxima) is the Sun’s closest stellar neighbour and one of the best-studied low-mass stars. It has an effective temperature of only around 3,050 kelvin, a luminosity of 0.15 per cent of that of the Sun, a measured radius of 14 per cent of the radius of the Sun and a mass of about 12 per cent of the mass of the Sun. Although Proxima is considered a moderately active star, its rotation period is about 83 days and its quiescent activity levels and X-ray luminosity are comparable to those of the Sun. Here we report observations that reveal the presence of a small planet with a minimum mass of about 1.3 Earth masses orbiting Proxima with a period of approximately 11.2 days at a semi-major-axis distance of around 0.05 astronomical units. Its equilibrium temperature is within the range where water could be liquid on its surface

STREAMFLOW REGIONALIZATION IN PIQUIRI RIVER BASIN

<div><p>ABSTRACT The objective of this study was to regionalize 7-day 10-year low flows, long-term annual mean, and 90% and 95% permanence flows from Piquiri (PR) river basin. The following regionalization methods were adopted: Traditional, Linear interpolation, Chaves, Modified linear interpolation, and Modified Chaves. The equations obtained by the Traditional method, adding main river length or drainage density as independent variables, significantly improved R2 equations value. Streamflow forecasting by Linear Interpolation and Chaves methods were as good as those provided by the Traditional Method, thus, these methods could be applied to Piquiri River basin, especially when drainage area is the only available spatial information.</p></div

Efeito das mudanças climáticas na disponibilidade hídrica da bacia hidrográfica do Rio Paracatu Effect of the climate change on the water availability in the Paracatu river basin

O aumento da demanda pelo uso da água na bacia do Rio Paracatu vem ocasionando sérios problemas ambientais e conflitos entre os usuários. Para a gestão mais eficiente dos recursos hídricos, é importante o conhecimento do comportamento hidrológico da bacia hidrográfica, no presente e no futuro, devido às fortes evidências de mudanças climáticas no planeta. O objetivo deste trabalho foi estimar a tendência de variação da disponibilidade hídrica na bacia hidrográfica do Rio Paracatu, até o final deste século, considerando dois cenários contrastantes de mudanças climáticas, um para altas emissões de CO2 (A2) e outro para baixas (B2). Para atingir esse objetivo, foi realizado o downscaling das precipitações mensais para os anos de 2001 a 2099, simulados pelo modelo de circulação geral do Hadley Centre (HadCM3). As precipitações interpoladas serviram como entrada em modelo do tipo precipitação-vazão, que possibilitou a estimativa das vazões mínimas em 21 estações fluviométricas distribuídas na bacia. Para o cenário A2, verificou-se tendência de aumento na disponibilidade hídrica em todas as estações fluviométricas, variando de 31 a 131% até 2099. Para o cenário B2, não foi verificada nenhuma tendência significativa.<br>The increase of water use in the Paracatu basin is leading to deep environmental problems and conflicts among the users. For a more efficient water resources management, the knowledge of the basin's hydrologic behavior is important, in the present and in the future, due to the strong climatic changes evidences in the planet. The aim of this work is to estimate the water availability variation trends in the Paracatu river basin, from the beginning until the end of this century, considering two contrasting climate change scenarios, the first one to take account of high CO2 emissions (A2) and the other one for low emissions (B2). To achieve this objective, the monthly precipitation downscaling was accomplished, using data from 2001 to 2099 simulated by the Hadley Centre´s global circulation model (HadCM3). The precipitations were used as data input in a precipitation-flow model, which made possible the estimate of the minimum discharges in 21 gauged stations distributed in the basin. For the A2 scenario, an increase trend was verified in the water availability in all of the stations from 2001 to 2099, varying from 31 to 131%. For the B2 scenario no significant trend was verified

Thrombotic and hemorrhagic complications of COVID-19 in adults hospitalized in high-income countries compared with those in adults hospitalized in low- and middle-income countries in an international registry

Background: COVID-19 has been associated with a broad range of thromboembolic, ischemic, and hemorrhagic complications (coagulopathy complications). Most studies have focused on patients with severe disease from high-income countries (HICs). Objectives: The main aims were to compare the frequency of coagulopathy complications in developing countries (low- and middle-income countries [LMICs]) with those in HICs, delineate the frequency across a range of treatment levels, and determine associations with in-hospital mortality. Methods: Adult patients enrolled in an observational, multinational registry, the International Severe Acute Respiratory and Emerging Infections COVID-19 study, between January 1, 2020, and September 15, 2021, met inclusion criteria, including admission to a hospital for laboratory-confirmed, acute COVID-19 and data on complications and survival. The advanced-treatment cohort received care, such as admission to the intensive care unit, mechanical ventilation, or inotropes or vasopressors; the basic-treatment cohort did not receive any of these interventions. Results: The study population included 495,682 patients from 52 countries, with 63% from LMICs and 85% in the basic treatment cohort. The frequency of coagulopathy complications was higher in HICs (0.76%-3.4%) than in LMICs (0.09%-1.22%). Complications were more frequent in the advanced-treatment cohort than in the basic-treatment cohort. Coagulopathy complications were associated with increased in-hospital mortality (odds ratio, 1.58; 95% CI, 1.52-1.64). The increased mortality associated with these complications was higher in LMICs (58.5%) than in HICs (35.4%). After controlling for coagulopathy complications, treatment intensity, and multiple other factors, the mortality was higher among patients in LMICs than among patients in HICs (odds ratio, 1.45; 95% CI, 1.39-1.51). Conclusion: In a large, international registry of patients hospitalized for COVID-19, coagulopathy complications were more frequent in HICs than in LMICs (developing countries). Increased mortality associated with coagulopathy complications was of a greater magnitude among patients in LMICs. Additional research is needed regarding timely diagnosis of and intervention for coagulation derangements associated with COVID-19, particularly for limited-resource settings

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

Background: The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms. Methods: International, prospective observational study of 60 109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms. Results: ‘Typical’ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (≤ 18&nbsp;years: 69, 48, 23; 85%), older adults (≥ 70&nbsp;years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each P &lt; 0.001). The most common atypical presentations under 60&nbsp;years of age were nausea and vomiting and abdominal pain, and over 60&nbsp;years was confusion. Regression models showed significant differences in symptoms with sex, age and country. Interpretation: This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30&nbsp;years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60&nbsp;years. Women are less likely to experience typical symptoms than men

Characteristics and outcomes of an international cohort of 600 000 hospitalized patients with COVID-19

Background: We describe demographic features, treatments and clinical outcomes in the International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) COVID-19 cohort, one of the world’s largest international, standardized data sets concerning hospitalized patients. Methods: The data set analysed includes COVID-19 patients hospitalized between January 2020 and January 2022 in 52 countries. We investigated how symptoms on admission, co-morbidities, risk factors and treatments varied by age, sex and other characteristics. We used Cox regression models to investigate associations between demographics, symptoms, co-morbidities and other factors with risk of death, admission to an intensive care unit (ICU) and invasive mechanical ventilation (IMV). Results: Data were available for 689 572 patients with laboratory-confirmed (91.1%) or clinically diagnosed (8.9%) SARS-CoV-2 infection from 52 countries. Age [adjusted hazard ratio per 10 years 1.49 (95% CI 1.48, 1.49)] and male sex [1.23 (1.21, 1.24)] were associated with a higher risk of death. Rates of admission to an ICU and use of IMV increased with age up to age 60 years then dropped. Symptoms, co-morbidities and treatments varied by age and had varied associations with clinical outcomes. The case-fatality ratio varied by country partly due to differences in the clinical characteristics of recruited patients and was on average 21.5%. Conclusions: Age was the strongest determinant of risk of death, with a ~30-fold difference between the oldest and youngest groups; each of the co-morbidities included was associated with up to an almost 2-fold increase in risk. Smoking and obesity were also associated with a higher risk of death. The size of our international database and the standardized data collection method make this study a comprehensive international description of COVID-19 clinical features. Our findings may inform strategies that involve prioritization of patients hospitalized with COVID-19 who have a higher risk of death