Local status and power in area-based health improvement partnerships

This is the authors' PDF version of an article published in Health© 2014. The definitive version is available at http://hea.sagepub.comArea-based initiatives (ABIs) have formed an important part of public policy towards more socio-economically deprived areas in many countries. Co-ordinating service provision within and across sectors has been a common feature of these initiatives. Despite sustained policy interest in ABIs, little empirical work has explored relations between ABI providers and partnership development within this context remains under-theorised. This paper addresses both of these gaps by exploring partnerships as a social and developmental process, drawing on concepts from figurational sociology to explain how provider relations develop within an ABI. Qualitative methods were used to explore, prospectively, the development of an ABI targeted at a town in the north west of England. A central finding was that, although effective delivery of ABIs is premised on a high level of coordination between service providers, the pattern of interdependencies between providers limits the frequency and effectiveness of cooperation. In particular, the interdependency of ABI providers with others in their organisation (what is termed here ‘organisational pull’) constrained the ways in which they worked with providers outside of their own organisations. ‘Local’ status, which could be earned over time, enabled some providers to exert greater control over the way in which provider relations developed during the course of the initiative. These findings demonstrate how historically constituted social networks, within which all providers are embedded, shape partnership development. The theoretical insight developed here suggests a need for more realistic expectations among policy makers about how and to what extent provider partnerships can be managed. Keywords: partnership, collaboration, community services, area-based initiatives, organisational pull, figurational sociologyNational Health Service (NHS

Static potential in scalar QED3_3 with non-minimal coupling

Here we compute the static potential in scalar $QED_3$ at leading order in $1/N_f$. We show that the addition of a non-minimal coupling of Pauli-type (\eps j^{\mu}\partial^{\nu}A^{\alpha}), although it breaks parity, it does not change the analytic structure of the photon propagator and consequently the static potential remains logarithmic (confining) at large distances. The non-minimal coupling modifies the potential, however, at small charge separations giving rise to a repulsive force of short range between opposite sign charges, which is relevant for the existence of bound states. This effect is in agreement with a previous calculation based on M$\ddot{o}$ller scattering, but differently from such calculation we show here that the repulsion appears independently of the presence of a tree level Chern-Simons term which rather affects the large distance behavior of the potential turning it into constant.Comment: 13 pages, 3 figure

A new spin-2 self-dual model in D=2+1D=2+1

There are three self-dual models of massive particles of helicity +2 (or -2) in $D=2+1$. Each model is of first, second, and third-order in derivatives. Here we derive a new self-dual model of fourth-order, \cL {SD}^{(4)}, which follows from the third-order model (linearized topologically massive gravity) via Noether embedment of the linearized Weyl symmetry. In fact, each self-dual model can be obtained from the previous one \cL {SD}^{(i)} \to \cL {SD}^{(i+1)}, i=1,2,3 by the Noether embedment of an appropriate gauge symmetry, culminating in \cL {SD}^{(4)}. The new model may be identified with the linearized version of \cL {HDTMG} = \epsilon^{\mu\nu\rho} \Gamma_{\mu\gamma}^\epsilon (\p_\nu\Gamma_{\epsilon\rho}^\gamma + (2/3)\Gamma_{\nu\delta}^\gamma \Gamma_{\rho\epsilon}^\delta) /8 m + \sqrt{-g}(R_{\mu\nu} R^{\nu\mu} - 3 R^2/8) /2 m^2 . We also construct a master action relating the third-order self-dual model to \cL {SD}^{(4)} by means of a mixing term with no particle content which assures spectrum equivalence of \cL {SD}^{(4)} to other lower-order self-dual models despite its pure higher derivative nature and the absence of the Einstein-Hilbert action. The relevant degrees of freedom of \cL {SD}^{(4)} are encoded in a rank-two tensor which is symmetric, traceless and transverse due to trivial (non-dynamic) identities, contrary to other spin-2 self-dual models. We also show that the Noether embedment of the Fierz-Pauli theory leads to the new massive gravity of Bergshoeff, Hohm and Townsend.Comment: 14 pages, no figures, typos fixed, reference (19) modifie

Dual descriptions of spin two massive particles in D=2+1D=2+1 via master actions

In the first part of this work we show the decoupling (up to contact terms) of redundant degrees of freedom which appear in the covariant description of spin two massive particles in $D=2+1$. We make use of a master action which interpolates, without solving any constraints, between a first, second and third order (in derivatives) self-dual model. An explicit dual map between those models is derived. In our approach the absence of ghosts in the third order self-dual model, which corresponds to a quadratic truncation of topologically massive gravity, is due to the triviality (no particle content) of the Einstein-Hilbert action in $D=2+1$. In the second part of the work, also in $D=2+1$, we prove the quantum equivalence of the gauge invariant sector of a couple of self-dual models of opposite helicities (+2 and -2) and masses $m_+$ and $m_-$ to a generalized self-dual model which contains a quadratic Einstein-Hilbert action, a Chern-Simons term of first order and a Fierz-Pauli mass term. The use of a first order Chern-Simons term instead of a third order one avoids conflicts with the sign of the Einstein-Hilbert action.Comment: title and abstract slightly modified, 3 references added, comments on interactions include

Overexpression of hedgehog signaling is associated with epidermal tumor formation in vitamin D receptor-null mice.

The vitamin D receptor (VDR) ligand, 1,25 dihydroxyvitamin D(3) (1,25(OH)(2)D(3)), reduces proliferation and enhances differentiation, and thus has been investigated for a role in preventing or treating cancer. Mice deficient for the VDR display a hyperproliferative response in the hair follicle and epidermis and decreased epidermal differentiation. Unlike their wild-type littermates, when treated with 7,12 dimethylbenzanthracene (DMBA) or UVB, they develop skin tumors, including some characteristic of overexpression of the hedgehog (Hh) pathway. Both the epidermis and utricles of the VDR-null animals overexpress elements of the Hh pathway (sonic hedgehog (Shh) 2.02-fold, patched1 1.58-fold, smoothened 3.54-fold, glioma-associated oncogene homolog (Gli)1 1.17-fold, and Gli2 1.66-fold). This overexpression occurs at an age (11 weeks) at which epidermal hyperproliferation is most visible and is spatially controlled in the epidermis. DMBA- or UVB-induced tumors in the VDR-null mice also overexpress elements of this pathway. Moreover, 1,25(OH)(2)D(3) downregulates the expression of some members of the Hh pathway in an epidermal explants culture system, suggesting a direct regulation by 1,25(OH)(2)D(3). Our results suggest that increased expression of Shh in the keratinocytes of the VDR-null animal activates the Hh pathway, predisposing the skin to the development of both malignant and benign epidermal neoplasms

Higher Order Stability of a Radiatively Induced 220 GeV Higgs Mass

The effective potential for radiatively broken electroweak symmetry in the single Higgs doublet Standard Model is explored to four sequentially subleading logarithm-summation levels (5-loops) in the dominant Higgs self-interaction couplant $\lambda$. We augment these results with all contributing leading logarithms in the remaining large but sub-dominant Standard Model couplants (t-quark, QCD and $SU(2)\otimes U(1)$ gauge couplants) as well as next to leading logarithm contributions from the largest of these, the t-quark and QCD couplants. Order-by-order stability is demonstrated for earlier leading logarithm predictions of an order 220 GeV Higgs boson mass in conjunction with fivefold enhancement of the value for $\lambda$ over that anticipated from conventional spontaneous symmetry breaking.Comment: revtex, 6 pages. Analysis and text is expanded in revised versio

Consistently computing the K -> pi long distance weak transition

First we extract the long-distance (LD) weak matrix element from certain data and give compatible theoretical estimates. We also link this LD scale to the single-quark-line (SQL) transition scale and then test the latter SQL scale against the decuplet weak decay amplitude ratio. Finally, we study LD decay. All of these experimental and theoretical values are in good agreement. We deduce an average value from eleven experimental determinations compared to the theoretical SQL values average.Comment: 19 pages, 9 figures minor change to the Conclusions and abstract sectio

Neuroendocrine Regulation of Metabolism

Given the current environment in most developed countries, it is a challenge to maintain a good balance between calories consumed and calories burned, although maintenance of metabolic balance is key to good health. Therefore, understanding how metabolic regulation is achieved and how the dysregulation of metabolism affects health is an area of intense research. Most studies focus on the hypothalamus, which is a brain area that acts as a key regulator of metabolism. Among the nuclei that comprise the hypothalamus, the arcuate nucleus is one of the major mediators in the regulation of food intake. The regulation of energy balance is also a key factor ensuring the maintenance of any species as a result of the dependence of reproduction on energy stores. Adequate levels of energy reserves are necessary for the proper functioning of the hypothalamic-pituitary-gonadal axis. This review discusses valuable data presented in the 2015 edition of the International Workshop of Neuroendocrinology concerning the fundamental nature of the hormonal regulation of the hypothalamus and the impact on energy balance and reproduction.Fil: Cornejo, María Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; ArgentinaFil: Hentges, S.T.. State University of Colorado - Fort Collins; Estados UnidosFil: Maliqueo, M.. Universidad de Chile; ChileFil: Coirini, Hector. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Becu Villalobos, D.. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Elias, C. F.. University of Michigan; Estados Unido

Physical and Spectral Characteristics of the T8 and Later-Type Dwarfs

We use new and published near-IR spectra, with synthetic spectra, to derive physical properties of three of the latest-type T dwarfs. A new R~1700 spectrum of the T7.5 dwarf HD 3651B, with existing data, allows a detailed comparison to the well-studied and very similar dwarf, Gl 570D. We find that HD 3651B has both higher gravity and metallicity than Gl 570D, with Teff=820-830K, log g= 5.4-5.5, [m/H]= +0.2 and Kzz=10^4cm^2/s. Its age is 8-12 Gyr and its implied mass is 60-70 M_Jup. We perform a similar analyis of the T8 and T7.5 dwarfs 2MASS J09393548-2448279 and 2MASS J11145133-2618235 using published data, comparing them to the well-studied T8, 2MASS J04151954-0935066. We find that the two dwarfs have the same Teff as the reference dwarf, and similar gravities, but lower metallicities. The parameters are Teff=725-775K and [m/H]= -0.3; log g=5.3-5.45 for 2MASS J09393548-2448279 and log g=5.0-5.3 for 2MASS J11145133- 261823. The age and mass are ~10Gyr and 60M_Jup for 2MASS J09393548-2448279, and ~5 Gyr and 40M_Jup for 2MASS J11145133-261823. A serious limitation is the incompleteness of the line lists of CH4 and NH3 at lambda <1.7um. Spectra of Saturn and Jupiter, and of laboratory CH4 and NH3 gas, suggest that NH3 features in the Y- and J-bands may be useful as indicators of the next cooler spectral type, and not features in the H- and K-bands as previously thought. However large uncertainties remain, as the abundance of NH3 is likely to be significantly below the chemical equilibrium value, and inclusion of laboratory NH3 opacities predicts band shapes that are discrepant with existing data. It is possible that the T spectral class will have to be extended to low temperatures around 400K, when water clouds condense in the atmosphere [abridged].Comment: 34 pages including 10 figures and two tables; accepted for publication in the Astrophysical Journa