2,935 research outputs found
Observable consequences of quantum gravity: Can light fermions exist?
Any theory of quantum gravity must ultimately be connected to observations.
This demand is difficult to be met due to the high energies at which we expect
the quantum nature of gravity to become manifest. Here we study, how viable
quantum gravity proposals can be restricted by investigating the interplay of
gravitational and matter degrees of freedom. Specifically we demand that a
valid quantum theory of gravity must allow for the existence of light (compared
to the Planck scale) fermions, since we observe these in our universe. Within
the effective theory framework, we can thus show that UV completions for
gravity are restricted, regardless of the details of the microscopic theory.
Specialising to asymptotically safe quantum gravity, we find indications that
universes with light fermions are favoured within this UV completion for
gravity.Comment: 4 pages, based on a talk given at Loops '11, Madrid, to appear in
Journal of Physics: Conference Series (JPCS
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Poly(A)-tail profiling reveals an embryonic switch in translational control
Poly(A) tails enhance the stability and translation of most eukaryotic mRNAs, but difficulties in globally measuring poly(A)-tail lengths have impeded greater understanding of poly(A)-tail function. Here, we describe poly(A)-tail length profiling by sequencing (PAL-seq) and apply it to measure tail lengths of millions of individual RNAs isolated from yeasts, cell lines, Arabidopsis leaves, mouse liver, and zebrafish and frog embryos. Poly(A)-tail lengths were conserved between orthologous mRNAs, with mRNAs encoding ribosomal proteins and other “housekeeping” proteins tending to have shorter tails. As expected, tail lengths were coupled to translational efficiency in early zebrafish and frog embryos. However, this strong coupling diminished at gastrulation and was absent in non-embryonic samples, indicating a rapid developmental switch in the nature of translational control. This switch complements an earlier switch to zygotic transcriptional control and explains why the predominant effect of microRNA-mediated deadenylation concurrently shifts from translational repression to mRNA destabilization
Seasonal variation in sex-specific immunity in wild birds
Whilst the immune system often varies seasonally and exhibits differences between males and
females, the general patterns in seasonality and sex differences across taxa have remained
controversial. Birds are excellent model organisms to assess these patterns, because the immune
system of many species is well characterised. We conducted a meta-analysis using 41 wild bird
species from 24 avian families to investigate sex differences and seasonal (breeding/non-breeding)
variations in immune status, including white blood cell counts, phytohaemagglutinin (PHA) test,
bacteria-killing ability (BKA), haemolysis and haemagglutination assays. We found male-biased
macrophage concentration, BKA and haemolysis titers, but only during the breeding season. Sexspecific
heterophil concentrations, heterophil/lymphocyte ratios and PHA responses differed between
breeding and non-breeding, suggesting larger changes in males than in females. Importantly, sex
differences in immune status are stronger during the breeding period than during the non-breeding
period. Taken together, our study suggests that both seasonal variation and sex differences in immune
system are common in birds, although their associations are more complex than previously thoughtPeer reviewe
Structural and Magnetic Dynamics in the Magnetic Shape Memory Alloy NiMnGa
Magnetic shape memory Heusler alloys are multiferroics stabilized by the
correlations between electronic, magnetic and structural order. To study these
correlations we use time resolved x-ray diffraction and magneto-optical Kerr
effect experiments to measure the laser induced dynamics in a Heusler alloy
NiMnGa film and reveal a set of timescales intrinsic to the system. We
observe a coherent phonon which we identify as the amplitudon of the modulated
structure and an ultrafast phase transition leading to a quenching of the
incommensurate modulation within 300~fs with a recovery time of a few ps. The
thermally driven martensitic transition to the high temperature cubic phase
proceeds via nucleation within a few ps and domain growth limited by the speed
of sound. The demagnetization time is 320~fs, which is comparable to the
quenching of the structural modulation.Comment: 5 pages, 3 figures. Supplementary materials 5 pages, 5 figure
Fractal space-times under the microscope: A Renormalization Group view on Monte Carlo data
The emergence of fractal features in the microscopic structure of space-time
is a common theme in many approaches to quantum gravity. In this work we carry
out a detailed renormalization group study of the spectral dimension and
walk dimension associated with the effective space-times of
asymptotically safe Quantum Einstein Gravity (QEG). We discover three scaling
regimes where these generalized dimensions are approximately constant for an
extended range of length scales: a classical regime where , a
semi-classical regime where , and the UV-fixed point
regime where . On the length scales covered by
three-dimensional Monte Carlo simulations, the resulting spectral dimension is
shown to be in very good agreement with the data. This comparison also provides
a natural explanation for the apparent puzzle between the short distance
behavior of the spectral dimension reported from Causal Dynamical
Triangulations (CDT), Euclidean Dynamical Triangulations (EDT), and Asymptotic
Safety.Comment: 26 pages, 6 figure
Superbase ionic liquids for effective cellulose processing from dissolution to carbonisation
This is the author accepted manuscript. The final version is available from Royal Society of Chemistry via the DOI in this recordA range of superbase derived ionic liquids (SILs) was synthesised and characterised. Their ability to dissolve cellulose and the characteristics of the produced fibres were correlated to their specific structural and solvent properties. 17 ionic liquids (ILs) (including 9 novel) were analysed and six ILs were selected to produce fibres: 1-ethyl-3-methylimidazolium acetate [C2C1im][OAc], 1-ethyl-3-methylimidazolium diethyl phosphate [C2C1im][DEP] and the SILs 1-ethyl-1,8-diazabicyclo[5.4.0]undec-7-enium diethylphosphate [DBUEt][DEP], 1,8-diazabicyclo[5.4.0]undec-7-enium acetate [DBUH][OAc], 1,5-diazabicyclo[4.3.0]non-5-enium acetate [DBNH][OAc] and 1-ethyl-1,5-diazabicyclo[4.3.0]non-5-enium diethylphsophate [DBNEt][DEP]. The mechanical properties of these fibres were investigated. The obtained fibres were then carbonised to explore possible application as carbon fibre precursors. The fibres obtained using a mixture of 1,5-diazabicyclo[4.3.0]non-5-enium based SILs with acetate and hexanoate anions (9 : 1), [DBNH][OAc][Hex], showed a promising combination of strength, stiffness and strain at failure values for applications in textiles and fibre reinforcement in renewable composites. Using Raman spectroscopy it is demonstrated that these fibres exhibit a relatively high degree of structural order, with fewer defects than the other materials. On the other hand, analogous fibres based on imidazolium cation with acetate and hexanoate anions (9 : 1), [C2C1im][OAc][Hex] showed a decline in the quality of the produced fibres compared to the fibres produced from [C2C1im][OAc], [C2C1im][DEP] or [DBNH][OAc][Hex].We would like to thank the EPSRC grant number EP/L017679/01 for financial support (AERO RB1717)
Infrared fixed point in quantum Einstein gravity
We performed the renormalization group analysis of the quantum Einstein
gravity in the deep infrared regime for different types of extensions of the
model. It is shown that an attractive infrared point exists in the broken
symmetric phase of the model. It is also shown that due to the Gaussian fixed
point the IR critical exponent of the correlation length is 1/2. However,
there exists a certain extension of the model which gives finite correlation
length in the broken symmetric phase. It typically appears in case of models
possessing a first order phase transitions as is demonstrated on the example of
the scalar field theory with a Coleman-Weinberg potential.Comment: 9 pages, 7 figures, final version, to appear in JHE
Conformal gauge-Yukawa theories away from four dimensions
We present the phase diagram and associated fixed points for a wide class of Gauge-Yukawa theories in d=4+ϵ dimensions. The theories we investigate involve non-abelian gauge fields, fermions and scalars in the Veneziano-Witten limit. The analysis is performed in steps, we start with QCD d and then we add Yukawa interactions and scalars which we study at next-to- and next-to-next-to-leading order. Interacting infrared fixed points naturally emerge in dimensions lower than four while ultraviolet ones appear above four. We also analyse the stability of the scalar potential for the discovered fixed points. We argue for a very rich phase diagram in three dimensions while in dimensions higher than four certain Gauge-Yukawa theories are ultraviolet complete because of the emergence of an asymptotically safe fixed point
Defect Engineering of Ta3N5 Photoanodes: Enhancing Charge Transport and Photoconversion Efficiencies via Ti Doping
While Ta3N5 shows excellent potential as a semiconductor photoanode for solar water splitting, its performance is hindered by poor charge carrier transport and trapping due to native defects that introduce electronic states deep within its bandgap. Here, it is demonstrated that controlled Ti doping of Ta3N5 can dramatically reduce the concentration of deep-level defects and enhance its photoelectrochemical performance, yielding a sevenfold increase in photocurrent density and a 300 mV cathodic shift in photocurrent onset potential compared to undoped material. Comprehensive characterization reveals that Ti4+ ions substitute Ta5+ lattice sites, thereby introducing compensating acceptor states, reducing the concentrations of deleterious nitrogen vacancies and reducing Ta3+ states, and thereby suppressing trapping and recombination. Owing to the similar ionic radii of Ti4+ and Ta5+, substitutional doping does not introduce lattice strain or significantly affect the underlying electronic structure of the host semiconductor. Furthermore, Ti can be incorporated without increasing the oxygen donor content, thereby enabling the electrical conductivity to be tuned by over seven orders of magnitude. Thus, Ti doping of Ta3N5 provides a powerful basis for precisely engineering its optoelectronic characteristics and to substantially improve its functional characteristics as an advanced photoelectrode for solar fuels applications
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