Saliva and tongue coating pH before and after use of mouthwashes and relationship with parameters of halitosis

OBJECTIVES: The aim of this work was to evaluate saliva and tongue coating pH in oral healthy patients with morning bad breath before and after use of different oral mouthrinses. MATERIAL AND METHODS: Saliva and tongue coating pH of 50 patients allocated in 5 groups were measured respectively by a digital pHmeter and color pH indicators, before, immediately after and 30 min after rinsing 5 different mouthrinses: cetilpiridine chloride associated with sodium chloride, triclosan, enzymatic solution, essential oil and distilled water. RESULTS: Only triclosan and essential oil increased salivary pH immediately after rising. The enzymatic solution decreased salivary and tongue coating pH immediately after rinsing. CONCLUSIONS: Salivary pH tended to be acidic while tongue coating pH tended to be alkaline, even after rising. Triclosan and essential oil mouthrinses increased salivary pH immediately after rinsing. Enzymatic solution decreased saliva and tongue coating pH immediately after rising.Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES

Evaluation of halitosis and sialometry in patients submitted to head and neck radiotherapy

Objectives: The aim of this study was to investigate the parameters of halitosis and sialometry in patients who had undergone head and neck radiotherapy, correlating oral concentration of volatile sulfur compounds (VSC) with the presence of tongue coating, salivary flow rate and BANA test. Material and Methods: 35 patients allocated in two groups were examined: group I (control) - patients with systemic and oral health; group II - patients submitted to head and neck radiotherapy. All volunteers were submitted to halitosis measurements through a sulphide monitor, evaluation of tongue coating weight, non-stimulated sialometry and BANA test. Results: The results were analyzed through analysis of variance, Pearson?s correlation and Student?s t-test, showing that there was statistically significant difference in halimetry between the groups, where the irradiated patients showed halitosis. There was a relation between the presence of tongue coating and the levels of VSCs in both groups and it was also noted that the irradiated patients showed a decreased salivary flow rate compared to healthy patients. Conclusion: On the conditions of the present research, it was concluded that halitosis can be considered an adverse effect of radiotherapy, connected to hiposalivation and poor oral health

Ameloblastic Fibro-Odontoma: A Diagnostic Challenge

An 11-year-old girl presented to our department to have a second opinion regarding a lesion involving her left mandible. She had previously undergone several radiographic exams including panoramic, helical, and cone-beam computed tomography. Radiographic examinations revealed a well-defined radiolucent region, which contained an irregular radiopaque mass of 3 cm in diameter, localized to the left angle of the mandible. Our presumptive diagnosis was complex odontoma. Excisional biopsy was performed, and microscopic features showed strands and islands of odontogenic epithelium showing peripheral palisading and loosely arranged central cells, identical to stellate reticulum, embedded in a myxoid cell-rich stroma resembling the dental papilla. Dentin and enamel were also presented. The diagnosis was ameloblastic fibro-odontoma, which is a rare mixed odontogenic tumor, derived from epithelial and ectomesenchymal elements that form the dental tissues

Is there still a place for involutional melancholia nowadays?

Ethnopharmacological relevance: Rubus niveus Thunb. plant belongs to Rosaceae family and have been used traditionally to treat wounds, burns, inflammation, dysentery, diarrhea and for curing excessive bleeding during menstrual cycle. The present study was undertaken to investigate the in vivo genotoxicity of Rubus niveus aerial parts extract and its possible chemoprotection on doxorubicin (DXR)-induced DNA damage. In parallel, the main phytochemicals constituents in the extract were determined.Materials and methods: The animals were exposed to the extract for 24 and 48 h, and the doses selected were 500, 1000 and 2000 mg/kg b.w. administered by gavage alone or prior to DXR (30 mg/kg b.w.) administered by intraperitoneal injection. The endpoints analyzed were DNA damage in bone marrow and peripheral blood cells assessed by the alkaline alkaline (pH > 13) comet assay and bone marrow micronucleus test.Results and conclusion: The results of chemical analysis of the extract showed the presence of tormentic acid, stigmasterol, quercitinglucoronide (miquelianin) and niga-ichigoside F1 as main compounds. Both cytogenetic endpoints analyzed showed that there were no statistically significant differences (p > 0.05) between the negative control and the treated groups with the two higher doses of Rubus niveus extract alone, demonstrating absence of genotoxic and mutagenic effects. Aneugenic/clastogenic effect was observed only at 2000 mg/kg dose. On the other hand, in the both assays and all tested doses were observed a significant reduction of DNA damage and chromosomal aberrations in all groups co-treated with DXR and extract compared to those which received only DXR. These results indicate that Rubus niveus aerial parts extract did not revealed any genotoxic effect, but presented some aneugenic/clastogenic effect at higher dose; and suggest that it could be a potential adjuvant against development of second malignant neoplasms caused by the cancer chemotherapic DXR. (C) 2015 Elsevier Ireland Ltd. All rights reserved.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP

Efeito do controle da pressao venosa central na ocorrência de fibrilaçao atrial após revascularizaçao do miocárdio: estudo caso-controle

INTRODUÇAO: Este estudo teve como objetivo comparar a incidência de fibrilaçao atrial após revascularizaçao do miocárdio entre pacientes que tiveram a pressao venosa central rigorosamente controlada nas primeiras 48-72 horas de pós-operatório e pacientes que nao tiveram controle rigoroso. MÉTODO: Estudo observacional, do tipo caso-controle, realizado na Santa Casa de Misericórdia de Ponta Grossa. O caso foi composto por 80 pacientes avaliados prospectivamente submetidos a revascularizaçao miocárdica entre 2012 e 2014, os quais tiveram a pressao venosa central avaliada de duas em duas horas, nas primeiras 72 horas de pós-operatório, sendo administrada uma ampola de furosemida cada vez que a pressao atingiu o ponto de corte preestabelecido de forma randomizada em 15 cmH2O ou 20 cmH2O. Já o controle foi composto por 184 pacientes avaliados retrospectivamente submetidos a revascularizaçao miocárdica entre 2009 e 2012, antes do início da randomizaçao, nos quais o controle da pressao venosa central foi menos rigoroso, ficando a necessidade de uso de diurético a critério dos intensivistas. Avaliou-se a incidência de fibrilaçao atrial nas primeiras 72 horas de pós-operatório nos dois grupos. RESULTADOS: A incidência de fibrilaçao atrial foi menor no grupo caso (11,25%, 9 em 80), comparativamente ao grupo controle (23,35%, 43 em 184) (P = 0,03). Outras variáveis estudadas foram semelhantes entre os grupos, exceto o clearance de creatinina, que foi maior no grupo controle. CONCLUSAO: O presente estudo demonstra que o controle da pressao venosa central nas primeiras 72 horas de pós-operatório é capaz de reduzir a incidência de fibrilaçao atrial após revascularizaçao do miocárdio

Efeito do controle da pressao venosa central na ocorrência de fibrilaçao atrial após revascularizaçao do miocárdio: estudo caso-controle

INTRODUÇAO: Este estudo teve como objetivo comparar a incidência de fibrilaçao atrial após revascularizaçao do miocárdio entre pacientes que tiveram a pressao venosa central rigorosamente controlada nas primeiras 48-72 horas de pós-operatório e pacientes que nao tiveram controle rigoroso. MÉTODO: Estudo observacional, do tipo caso-controle, realizado na Santa Casa de Misericórdia de Ponta Grossa. O caso foi composto por 80 pacientes avaliados prospectivamente submetidos a revascularizaçao miocárdica entre 2012 e 2014, os quais tiveram a pressao venosa central avaliada de duas em duas horas, nas primeiras 72 horas de pós-operatório, sendo administrada uma ampola de furosemida cada vez que a pressao atingiu o ponto de corte preestabelecido de forma randomizada em 15 cmH2O ou 20 cmH2O. Já o controle foi composto por 184 pacientes avaliados retrospectivamente submetidos a revascularizaçao miocárdica entre 2009 e 2012, antes do início da randomizaçao, nos quais o controle da pressao venosa central foi menos rigoroso, ficando a necessidade de uso de diurético a critério dos intensivistas. Avaliou-se a incidência de fibrilaçao atrial nas primeiras 72 horas de pós-operatório nos dois grupos. RESULTADOS: A incidência de fibrilaçao atrial foi menor no grupo caso (11,25%, 9 em 80), comparativamente ao grupo controle (23,35%, 43 em 184) (P = 0,03). Outras variáveis estudadas foram semelhantes entre os grupos, exceto o clearance de creatinina, que foi maior no grupo controle. CONCLUSAO: O presente estudo demonstra que o controle da pressao venosa central nas primeiras 72 horas de pós-operatório é capaz de reduzir a incidência de fibrilaçao atrial após revascularizaçao do miocárdio

Health-related quality of life in patients with type 1 diabetes mellitus in the different geographical regions of Brazil : data from the Brazilian Type 1 Diabetes Study Group

Background: In type 1 diabetes mellitus (T1DM) management, enhancing health-related quality of life (HRQoL) is as important as good metabolic control and prevention of secondary complications. This study aims to evaluate possible regional differences in HRQoL, demographic features and clinical characteristics of patients with T1DM in Brazil, a country of continental proportions, as well as investigate which variables could influence the HRQoL of these individuals and contribute to these regional disparities. Methods: This was a retrospective, cross-sectional, multicenter study performed by the Brazilian Type 1 Diabetes Study Group (BrazDiab1SG), by analyzing EuroQol scores from 3005 participants with T1DM, in 28 public clinics, among all geographical regions of Brazil. Data on demography, economic status, chronic complications, glycemic control and lipid profile were also collected. Results: We have found that the North-Northeast region presents a higher index in the assessment of the overall health status (EQ-VAS) compared to the Southeast (74.6 ± 30 and 70.4 ± 19, respectively; p < 0.05). In addition, North- Northeast presented a lower frequency of self-reported anxiety-depression compared to all regions of the country (North-Northeast: 1.53 ± 0.6; Southeast: 1.65 ± 0.7; South: 1.72 ± 0.7; Midwest: 1.67 ± 0.7; p < 0.05). These findings could not be entirely explained by the HbA1c levels or the other variables examined. Conclusions: Our study points to the existence of additional factors not yet evaluated that could be determinant in the HRQoL of people with T1DM and contribute to these regional disparities

Tropical Fruit Pulps: Processing, Product Standardization and Main Control Parameters for Quality Assurance

ABSTRACT Fruit pulp is the most basic food product obtained from fresh fruit processing. Fruit pulps can be cold stored for long periods of time, but they also can be used to fabricate juices, ice creams, sweets, jellies and yogurts. The exploitation of tropical fruits has leveraged the entire Brazilian fruit pulp sector due mainly to the high acceptance of their organoleptic properties and remarkable nutritional facts. However, several works published in the last decades have pointed out unfavorable conditions regarding the consumption of tropical fruit pulps. This negative scenario has been associated with unsatisfactory physico-chemical and microbiological parameters of fruits pulps as outcomes of little knowledge and improper management within the fruit pulp industry. There are protocols for delineating specific identity and quality standards (IQSs) and standardized good manufacturing practices (GMP) for fruit pulps, which also embrace standard operating procedures (SOPs) and hazard analysis and critical control points (HACCP), although this latter is not considered mandatory by the Brazilian legislation. Unfortunately, the lack of skilled labor, along with failures in complying established protocols have impaired quality of fruit pulps. It has been necessary to collect all information available with the aim to identify the most important hazards within fruit pulp processing lines. Standardizing methods and practices within the Brazilian fruit pulp industry would assurance high quality status to tropical fruit pulps and the commercial growth of this vegetal product towards international markets

Educomunicação e suas áreas de intervenção: Novos paradigmas para o diálogo intercultural

oai:omp.abpeducom.org.br:publicationFormat/1O material aqui divulgado representa, em essência, a contribuição do VII Encontro Brasileiro de Educomunicação ao V Global MIL Week, da UNESCO, ocorrido na ECA/USP, entre 3&nbsp;e 5 de novembro de 2016. Estamos diante de um conjunto de 104 papers executivos, com uma média de entre 7 e 10 páginas, cada um. Com este rico e abundante material, chegamos ao sétimo e-book publicado pela ABPEducom, em seus seis primeiros anos de existência. A especificidade desta obra é a de trazer as “Áreas de Intervenção” do campo da Educomunicação, colocando-as a serviço de uma meta essencial ao agir educomunicativo: o diálogo intercultural, trabalhado na linha do tema geral do evento internacional: Media and Information Literacy: New Paradigms for Intercultural Dialogue