Nontypable Haemophilus influenzae Displays a Prevalent Surface Structure Molecular Pattern in Clinical Isolates

Non-typable Haemophilus influenzae (NTHi) is a Gram negative pathogen that causes acute respiratory infections and is associated with the progression of chronic respiratory diseases. Previous studies have established the existence of a remarkable genetic variability among NTHi strains. In this study we show that, in spite of a high level of genetic heterogeneity, NTHi clinical isolates display a prevalent molecular feature, which could confer fitness during infectious processes. A total of 111 non-isogenic NTHi strains from an identical number of patients, isolated in two distinct geographical locations in the same period of time, were used to analyse nine genes encoding bacterial surface molecules, and revealed the existence of one highly prevalent molecular pattern (lgtF+, lic2A+, lic1D+, lic3A+, lic3B+, siaA−, lic2C+, ompP5+, oapA+) displayed by 94.6% of isolates. Such a genetic profile was associated with a higher bacterial resistance to serum mediated killing and enhanced adherence to human respiratory epithelial cells

International Consensus Statement on Rhinology and Allergy: Rhinosinusitis

Background: The 5 years since the publication of the first International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed foundational progress in our understanding and treatment of rhinologic disease. These advances are reflected within the more than 40 new topics covered within the ICAR‐RS‐2021 as well as updates to the original 140 topics. This executive summary consolidates the evidence‐based findings of the document. Methods: ICAR‐RS presents over 180 topics in the forms of evidence‐based reviews with recommendations (EBRRs), evidence‐based reviews, and literature reviews. The highest grade structured recommendations of the EBRR sections are summarized in this executive summary. Results: ICAR‐RS‐2021 covers 22 topics regarding the medical management of RS, which are grade A/B and are presented in the executive summary. Additionally, 4 topics regarding the surgical management of RS are grade A/B and are presented in the executive summary. Finally, a comprehensive evidence‐based management algorithm is provided. Conclusion: This ICAR‐RS‐2021 executive summary provides a compilation of the evidence‐based recommendations for medical and surgical treatment of the most common forms of RS

The craniofacial indicators of aggression: a cross-sectional multiparametric anthropometry study

BACKGROUND: The craniofacial features of a person are unique and critical in the evaluation of age, gender, and ethnicity. The relationships between craniofacial properties and behavioural patterns have been one of the most common research topics. MATERIALS AND METHODS: There are studies on the association of facial width-to- -height ratio (fWHR) and aggressive behaviour in men; however, no consensus has been reached as there are inconsistent study results. Most of the studies focus on measuring the pre-determined fWHR in searching for a link to aggression. As the literature lacks data on the associations of multiple craniofacial ratios and aggression, we aimed to study the correlation of aggressive behaviour and multiparametric anthropometric measurements of the craniofacial region in a study group consisting of university students aging 18-38 years. RESULTS: The aggression questionnaire results showed that male students had statistically higher scores than females in all subdomains, except physical aggression. Anthropometric studies revealed that males had higher mean values of craniofacial dimensions and indices than females, except the frontal height, the total lip height, frontal index, and cranial length-head circumference index. The statistical analyses for correlations showed that frontal, upper facial, and total facial height-facial width indices correlated with general and verbal aggression, frontal and upper facial indices correlated with physical aggression, and upper facial and total facial height-facial width indices correlated with indirect aggression only in males. CONCLUSIONS: We conclude that our study represents the first example of an extensive craniofacial anthropometric research that correlates several craniofacial measurements and ratios with various aggression subdomains

Generation of a typical meteorological year using sunshine duration data

In this paper, we discuss the possibility of using the daily sunshine duration or the daily sunshine duration over day-length data instead of daily global solar radiation in order to develop a Typical Meteorological Year, TMY2, for localities with abundant data of daily sunshine duration. The analysis is done using the latest methodology proposed in the literature. The number of coinciding months is about 40% when daily sunshine duration or the daily sunshine duration over day-length data is used instead of daily global solar radiation as one of the parameters in obtaining TMY2. Such a relatively low figure is probably due to the unreliable solar radiation data recorded by Robitzch-type actinographs used in the present work. (C) 2002 Elsevier Science Ltd. All rights reserved

Usability of CART algorithm for determining egg quality characteristics influencing fertility in the eggs of Japanese quail

The objective of this study was to determine the effects of egg quality characteristics (egg weight, egg width, egg height, and shape index) on fertility of eggs of Japanese quail with different colored feathers (yellow, white, grizzled, and normal), which are of economic importance for poultry production. For this purpose, 383 eggs of Japanese quail with various feather colors were used. In the study, usability of classification and regression tree (CART) data-mining algorithm as a classification tree method is necessary for poultry breeders to define proper cut-off values of egg quality characteristics that ensure Japanese quail eggs at good quality in fertility. Fertility as the dependent variable in the study was examined as a binary trait (fertile and infertile) and all the egg quality traits accepted as explanatory variables were continuous variables. Feather color was also included as a nominal categorical explanatory variable. The classification tree results showed that the highest fertility ratio of 90.9% was obtained from the eggs of Japanese quail of white, grizzled, and normal feather colors with 10.425 g ? egg weight, 24.565 mm ? egg width, or the fertility ratio of 88.2% of the eggs was observed with 10.425 g ? egg weight and 25.605 mm ? egg width. Consequently, usability of the tree-based CART algorithm is important in practice for properly establishing fertilized eggs, depending on feather color types of Japanese quail. © 2016 Sociedade Brasileira de Zootecnia