966 research outputs found
Penis size: Survey of female perceptions of sexual satisfaction
BACKGROUND: Does the size of the male penis, in terms of length or width, make a difference in female sexual satisfaction? METHOD: To study the effect of penis width vs. length on female sexual satisfaction, 50 sexually active female undergraduate students were asked which felt better, i. e., was penis width or length more important for their sexual satisfaction. RESULTS: None reported they did not know, or that width and length were equally satisfying. A large majority, 45 of 50, reported width was more important (p < .001). CONCLUSION: Implications are discussed, including the fact that the data seem to contradict Masters and Johnson about penis size having no physiological effect on female sexual satisfaction
Using Systematic Observations to Understand Conditions that Promote Interracial Experiences in Neighbourhood Parks
We analysed observations from 31 neighbourhood parks, with each park mapped into smaller target areas for study, across five US cities generated using the System for Observing Play and Recreation in the Community (SOPARC). In areas where at least two people were observed, less than one-third (31.6%) were populated with at least one white and one non-white person. Park areas that were supervised, had one or more people engaged in vigorous activity, had at least one male and one female present, and had one or more teens present were significantly more likely to involve interracial groups (p \u3c 0.01 for each association). Observations in parks located in interracial neighbourhoods were also more likely to involve interracial groups (p \u3c 0.05). Neighbourhood poverty rate had a significant and negative relationship with the presence of interracial groups, particularly in neighbourhoods that are predominantly non-white. Additional research is needed to confirm the impact of these interactions. Urban planning and public health practitioners should consider the health benefits of interracial contact in the design and programming of neighbourhood parks
‘Stick that knife in me’: Shane Meadows’ children
This article brings Shane Meadows’ Dead Man's Shoes (2004) into dialogue with the history of the depiction of the child on film. Exploring Meadows’ work for its complex investment in the figure of the child on screen, it traces the limits of the liberal ideology of the child in his cinema and the structures of feeling mobilised by its uses – at once aesthetic and sociological – of technologies of vision
An interacting spin flip model for one-dimensional proton conduction
A discrete asymmetric exclusion process (ASEP) is developed to model proton
conduction along one-dimensional water wires. Each lattice site represents a
water molecule that can be in only one of three states; protonated,
left-pointing, and right-pointing. Only a right(left)-pointing water can accept
a proton from its left(right). Results of asymptotic mean field analysis and
Monte-Carlo simulations for the three-species, open boundary exclusion model
are presented and compared. The mean field results for the steady-state proton
current suggest a number of regimes analogous to the low and maximal current
phases found in the single species ASEP [B. Derrida, Physics Reports, {\bf
301}, 65-83, (1998)]. We find that the mean field results are accurate
(compared with lattice Monte-Carlo simulations) only in the certain regimes.
Refinements and extensions including more elaborate forces and pore defects are
also discussed.Comment: 13pp, 6 fig
Infrared temperature sounding - S-043 Final report, 1 Jul. 1967 - 31 Aug. 1969
Balloon-borne multidetector infrared grating spectrometer to measure earths radiance for atmospheric temperature profile determination
Diabetic Csf1op/op Mice Lacking Macrophages Are Protected Against the Development of Delayed Gastric Emptying
Background & AimsDiabetic gastroparesis is associated with changes in interstitial cells of Cajal (ICC), neurons, and smooth muscle cells in both animal models and humans. Macrophages appear to be critical to the development of cellular damage that leads to delayed gastric emptying (GE), but the mechanisms involved are not well understood. Csf1op/op (Op/Op) mice lack biologically active Csf1 (macrophage colony stimulating factor), resulting in the absence of Csf1-dependent tissue macrophages. We used Csf1op/op mice to determine the role of macrophages in the development of delayed GE.MethodsAnimals were injected with streptozotocin to make them diabetic. GE was determined weekly. Immunohistochemistry was used to identify macrophages and ICC networks in the gastric muscular layers. Oxidative stress was measured by serum malondialdehyde (MDA) levels. Quantitative reverse-transcription polymerase chain reaction was used to measure levels of mRNA.ResultsCsf1op/op mice had normal ICC. With onset of diabetes both Csf1op/op and wild-type Csf1+/+ mice developed increased levels of oxidative stress (75.8 ± 9.1 and 41.2 ± 13.6 nmol/mL MDA, respectively). Wild-type Csf1+/+ mice developed delayed GE after the onset of diabetes (4 of 13) whereas no diabetic Csf1op/op mouse developed delayed GE (0 of 15, P = .035). The ICC were disrupted in diabetic wild-type Csf1+/+ mice with delayed GE but remained normal in diabetic Csf1op/op mice.ConclusionsCellular injury and development of delayed GE in diabetes requires the presence of muscle layer macrophages. Targeting macrophages may be an effective therapeutic option to prevent cellular damage and development of delayed GE in diabetes
Overturning circulation, nutrient limitation, and warming in the Glacial North Pacific
This work was funded by NERC grant NE/N011716/1 to J.W.B.R., a NERC studentship to B.T., and NSF grant OPP 1643445 to I.E. A.R. acknowledges support from NSF grant 1736771.Although the Pacific Ocean is a major reservoir of heat and CO2, and thus an important component of the global climate system, its circulation under different climatic conditions is poorly understood. Here, we present evidence that during the Last Glacial Maximum (LGM), the North Pacific was better ventilated at intermediate depths and had surface waters with lower nutrients, higher salinity, and warmer temperatures compared to today. Modeling shows that this pattern is well explained by enhanced Pacific meridional overturning circulation (PMOC), which brings warm, salty, and nutrient-poor subtropical waters to high latitudes. Enhanced PMOC at the LGM would have lowered atmospheric CO2—in part through synergy with the Southern Ocean—and supported an equable regional climate, which may have aided human habitability in Beringia, and migration from Asia to North America.Publisher PDFPeer reviewe
Overview of NASA Technology Development for In-Situ Resource Utilization (ISRU)
In-Situ Resource Utilization (ISRU) encompasses a broad range of systems that enable the production and use of extraterrestrial resources in support of future exploration missions. It has the potential to greatly reduce the dependency on resources transported from Earth (e.g., propellants, life support consumables), thereby significantly improving the ability to conduct future missions. Recognizing the critical importance of ISRU for the future, NASA is currently conducting technology development projects in two of its four mission directorates. The Advanced Exploration Systems Division in the Agency's Human Exploration and Operations Mission Directorate has initiated a new project for ISRU Technology focused on component, subsystem, and system maturation in the areas of water volatiles resource acquisition, and water volatiles and atmospheric processing into propellants and other consumable products. The Space Technology Mission Directorate is supporting development of ISRU component technologies in the areas of Mars atmosphere acquisition, including dust management, and oxygen production from Mars atmosphere for propellant and life support consumables. Together, these two coordinated projects are working towards a common goal of demonstrating ISRU technology and systems in preparation for future flight applications
The effect of recombinant mast cell growth factor on purified murine hematopoietic stem cells.
How do general practitioners experience providing care to refugees with mental health problems? A qualitative study from Denmark
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
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