Quantifying non-stabilizerness through entanglement spectrum flatness

Non-stabilizerness - also colloquially referred to as magic - is the a resource for advantage in quantum computing and lies in the access to non-Clifford operations. Developing a comprehensive understanding of how non-stabilizerness can be quantified and how it relates other quantum resources is crucial for studying and characterizing the origin of quantum complexity. In this work, we establish a direct connection between non-stabilizerness and entanglement spectrum flatness for a pure quantum state. We show that this connection can be exploited to efficiently probe non-stabilizerness even in presence of noise. Our results reveal a direct connection between non-stabilizerness and entanglement response, and define a clear experimental protocol to probe non-stabilizerness in cold atom and solid-state platforms

Large-N Chern insulators: Lattice field theory and quantum simulation approaches to correlation effects in the quantum anomalous Hall effect

Four-Fermi quantum field theories in (2+1) dimensions lie among the simplest models in high-energy physics, the understanding of which requires a non-perturbative lattice formulation addressing their strongly-coupled fixed points. These lattice models are also relevant in condensed matter, as they offer a neat playground to explore strong correlations in the quantum anomalous Hall (QAH) effect. We give a detailed description of our multidisciplinary approach to understand the fate of the QAH phases as the four-Fermi interactions are increased, which combines strong-coupling and effective-potential techniques, unveiling a rich phase diagram with large-$N$ Chern insulators and Lorentz-breaking fermion condensates. Moreover, this toolbox can be enlarged with recent advances in quantum information science, as we show that tensor-network algorithms based on projected entangled pairs can be used to improve our understanding of the strong-coupling limit. We also present a detailed scheme that uses ultra-cold atoms in optical lattices with synthetic spin-orbit coupling to build quantum simulators of these four-Fermi models. This yields a promising alternative to characterise the strongly-coupled fixed points and, moreover, could also explore real-time dynamics and finite-fermion densities

Serum anti-GM2 and anti-GalNAc-GD1a IgG antibodies are biomarkers for acute canine polyradiculoneuritis

Objectives: A previous single-country pilot study indicated serum anti-GM2 and anti-GA1 anti-glycolipid antibodies as potential biomarkers for acute canine polyradiculoneuritis. This study aims to validate these findings in a large geographically heterogenous cohort. Materials and Methods: Sera from 175 dogs clinically diagnosed with acute canine polyradiculoneuritis, 112 dogs with other peripheral nerve, cranial nerve or neuromuscular disorders and 226 neurologically normal dogs were screened for anti-glycolipid antibodies against 11 common glycolipid targets to determine the immunoglobulin G anti-glycolipid antibodies with the highest combined sensitivity and specificity for acute canine polyradiculoneuritis. Results: Anti-GM2 anti-glycolipid antibodies reached the highest combined sensitivity and specificity (sensitivity: 65.1%, 95% confidence interval 57.6 to 72.2%; specificity: 90.2%, 95% confidence interval 83.1 to 95.0%), followed by anti-GalNAc-GD1a anti-glycolipid antibodies (sensitivity: 61.7%, 95% confidence interval 54.1 to 68.9%; specificity: 89.3%, 95% confidence interval 82.0 to 94.3%) and these anti-glycolipid antibodies were frequently present concomitantly. Anti-GA1 anti-glycolipid antibodies were detected in both acute canine polyradiculoneuritis and control animals. Both for anti-GM2 and anti-GalNAc-GD1a anti-glycolipid antibodies, sex was found a significantly associated factor with a female to male odds ratio of 2.55 (P=0.0096) and 3.00 (P=0.0198), respectively. Anti-GalNAc-GD1a anti-glycolipid antibodies were more commonly observed in dogs unable to walk (odds ratio 4.56; P=0.0076). Clinical Significance: Anti-GM2 and anti-GalNAc-GD1a immunoglobulin G anti-glycolipid antibodies represent serum biomarkers for acute canine polyradiculoneuritis

Serum anti-GM2 and anti-GalNAc-GD1a IgG antibodies are biomarkers for acute canine polyradiculoneuritis

OBJECTIVES: A previous single-country pilot study indicated serum anti-GM2 and anti-GA1 anti-glycolipid antibodies as potential biomarkers for acute canine polyradiculoneuritis. This study aims to validate these findings in a large geographically heterogenous cohort. MATERIALS AND METHODS: Sera from 175 dogs clinically diagnosed with acute canine polyradiculoneuritis, 112 dogs with other peripheral nerve, cranial nerve or neuromuscular disorders and 226 neurologically normal dogs were screened for anti-glycolipid antibodies against 11 common glycolipid targets to determine the immunoglobulin G anti-glycolipid antibodies with the highest combined sensitivity and specificity for acute canine polyradiculoneuritis. RESULTS: Anti-GM2 anti-glycolipid antibodies reached the highest combined sensitivity and specificity (sensitivity: 65.1%, 95% confidence interval 57.6 to 72.2%; specificity: 90.2%, 95% confidence interval 83.1 to 95.0%), followed by anti-GalNAc-GD1a anti-glycolipid antibodies (sensitivity: 61.7%, 95% confidence interval 54.1 to 68.9%; specificity: 89.3%, 95% confidence interval 82.0 to 94.3%) and these anti-glycolipid antibodies were frequently present concomitantly. Anti-GA1 anti-glycolipid antibodies were detected in both acute canine polyradiculoneuritis and control animals. Both for anti-GM2 and anti-GalNAc-GD1a anti-glycolipid antibodies, sex was found a significantly associated factor with a female to male odds ratio of 2.55 (1.27 to 5.31) and 3.00 (1.22 to 7.89), respectively. Anti-GalNAc-GD1a anti-glycolipid antibodies were more commonly observed in dogs unable to walk (OR 4.56, 1.56 to 14.87). CLINICAL SIGNIFICANCE: Anti-GM2 and anti-GalNAc-GD1a immunoglobulin G anti-glycolipid antibodies represent serum biomarkers for acute canine polyradiculoneuritis.This study was funded by PetSavers, the charitable division of the BSAVA, and by The Wellcome Trust (Grants 092805 and 202789 awarded to HJW).https://onlinelibrary.wiley.com/journal/17485827Companion Animal Clinical Studie

Serum anti-GM2 and anti-GalNAc-GD1a IgG antibodies are biomarkers for acute canine polyradiculoneuritis

Objectives: A previous single-country pilot study indicated serum anti-GM2 and anti-GA1 anti-glycolipid antibodies as potential biomarkers for acute canine polyradiculoneuritis. This study aims to validate these findings in a large geographically heterogenous cohort. Materials and Methods: Sera from 175 dogs clinically diagnosed with acute canine polyradiculoneuritis, 112 dogs with other peripheral nerve, cranial nerve or neuromuscular disorders and 226 neurologically normal dogs were screened for anti-glycolipid antibodies against 11 common glycolipid targets to determine the immunoglobulin G anti-glycolipid antibodies with the highest combined sensitivity and specificity for acute canine polyradiculoneuritis. Results: Anti-GM2 anti-glycolipid antibodies reached the highest combined sensitivity and specificity (sensitivity: 65.1%, 95% confidence interval 57.6 to 72.2%; specificity: 90.2%, 95% confidence interval 83.1 to 95.0%), followed by anti-GalNAc-GD1a anti-glycolipid antibodies (sensitivity: 61.7%, 95% confidence interval 54.1 to 68.9%; specificity: 89.3%, 95% confidence interval 82.0 to 94.3%) and these anti-glycolipid antibodies were frequently present concomitantly. Anti-GA1 anti-glycolipid antibodies were detected in both acute canine polyradiculoneuritis and control animals. Both for anti-GM2 and anti-GalNAc-GD1a anti-glycolipid antibodies, sex was found a significantly associated factor with a female to male odds ratio of 2.55 (P=0.0096) and 3.00 (P=0.0198), respectively. Anti-GalNAc-GD1a anti-glycolipid antibodies were more commonly observed in dogs unable to walk (odds ratio 4.56; P=0.0076). Clinical Significance: Anti-GM2 and anti-GalNAc-GD1a immunoglobulin G anti-glycolipid antibodies represent serum biomarkers for acute canine polyradiculoneuritis

Large-N Chern insulators: lattice field theory and quantum simulation approaches to correlation effects in the quantum anomalous Hall effect

CRUE-CSIC (Acuerdos Transformativos 2022). © 2022 The Author(s). His is an open access article under the CC BY-NC-ND license. The ICFO group acknowledges support from ERC AdG NOQIA, State Research Agency AEI (‘‘Severo Ochoa’’ Center of Excellence CEX2019-000910-S) Plan National FIDEUA PID2019-106901GB-I00 project funded by MCIN/AEI /10.13039/501100011033, FPI, QUANTERA MAQS PCI2019-111828-2 project funded by MCIN/AEI /10.13039/501100011033, Proyectos de I+D+I ‘‘Retos Colaboración’’ RTC2019-007196-7 project funded by MCIN/AEI /10.13039/501100011033, Fundació Privada Cellex, Fundació Mir-Puig, Generalitat de Catalunya (AGAUR Grant No. 2017 SGR 1341, CERCA program, QuantumCAT U16-011424, co-funded by ERDF Operational Program of Catalonia 2014–2020), EU Horizon 2020 FET-OPEN OPTOLogic (Grant No 899794), and the National Science Centre, Poland (Symfonia Grant No. 2016/20/W/ST4/00314), Marie Skłodowska-Curie grant STREDCH No 101029393, ‘‘La Caixa’’ Junior Leaders fellowships (ID100010434), and EU Horizon 2020 under Marie Skłodowska-Curie grant agreement No. 847648 (LCF/BQ/PI19/11690013, LCF/BQ/PI20/11760031, LCF/BQ/PR20/11770012).). A.B. acknowledges support from the Ramón y Cajal program RYC- 2016-20066, CAM/FEDER Project S2018/TCS- 4342 (QUITEMADCM), and PGC2018-099169-B-I00 (MCIU/AEI/FEDER, UE). S.J.H. acknowledges the support of STFC grant ST/T000813Four-Fermi quantum field theories in (2+1) dimensions lie among the simplest models in high-energy physics, the understanding of which requires a non-perturbative lattice formulation addressing their strongly-coupled fixed points. These lattice models are also relevant in condensed matter, as they offer a neat playground to explore strong correlations in the quantum anomalous Hall (QAH) effect. We give a detailed description of our multidisciplinary approach to understand the fate of the QAH phases as the four-Fermi interactions are increased, which combines strong-coupling and effective-potential techniques, unveiling a rich phase diagram with large -N Chern insulators and Lorentz breaking fermion condensates. Moreover, this toolbox can be enlarged with recent advances in quantum information science, as we show that tensor-network algorithms based on projected entangled pairs can be used to improve our understanding of the strong-coupling limit. We also present a detailed scheme that uses ultra-cold atoms in optical lattices with synthetic spin- orbit coupling to build quantum simulators of these four-Fermi models. This yields a promising alternative to characterize the strongly-coupled fixed points and, moreover, could also explore real-time dynamics and finite-fermion densities.(c) 2022 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).Unión Europea. Horizonte 2020Ministerio de Ciencia e Innovación (MICINN)/AEIMinisterio de Ciencia, Innovación y Universidades (MCIU)/AEI/FEDERNational Science Centre, PolandComunidad de Madrid/FEDERGeneralidad de Cataluña/FEDERCentros de Excelencia Severo Ochoa (MICINN)Programa Ramón y CajalDepto. de Física TeóricaFac. de Ciencias FísicasTRUEpu

Patterns of expression of <i>POMC</i>, <i>PC1</i> and <i>PC2</i> in feather follicles at E8 and E12.

<p>The epidermis is labelled with a small black arrow and feather follicles with a large blue arrow. <i>POMC</i> is expressed in the dermal pulp of ventral and dorsal feather follicles in E8 and E12 embryos. Weak expression of <i>PC1</i> was observed in developing feather follicles but did not develop further at E12. There is weak transcription of <i>PC2</i> at E8 on both ventral and dorsal surfaces, but when feather development is more progressed (e.g. E12), <i>PC2</i> is strongly expressed in feather follicles on both the ventral and dorsal surface.</p