4,951 research outputs found
A stroking device for spatially separated couples
In this paper we present a device to support the communication of couples in long-distance relationships. While a synchronous exchange of factual information over distance is supported by telephone, e-mail and chat-systems, the transmission of nonverbal aspects of communication is still unsatisfactory. Videocalls let us see the partners’ facial expression in real time. However, to experience a more intimate conversation physical closeness is needed. Stroking while holding hands is a special and emotional gesture for couples. Hence, we developed a device that enables couples to exchange the physical gesture of stroking regardless of distance and location. The device allows both sending and receiving. A user test supported our concept and provided new insights for future development
Platelet kinetics in the pulmonary microcirculation in vivo assessed by intravital microscopy
Growing evidence supports the substantial pathophysiological impact of platelets on the development of acute lung injury. Methods for studying these cellular mechanisms in vivo are not present yet. The aim of this study was to develop a model enabling the quantitative analysis of platelet kinetics and platelet-endothelium interaction within consecutive segments of the pulmonary microcirculation in vivo. New Zealand White rabbits were anesthetized and ventilated. Autologous platelets were separated from blood and labeled ex vivo with rhodamine 6G. After implantation of a thoracic window, microhemodynamics and kinetics of platelets were investigated by intravital microscopy. Velocities of red blood cells (RBCs) and platelets were measured in arterioles, capillaries and venules, and the number of platelets adhering to the microvascular endothelium was counted. Kinetics of unstimulated platelets was compared with kinetics of thrombin-activated platelets. Velocity of unstimulated platelets was comparable to RBC velocity in all vessel segments. Unstimulated platelets passed the pulmonary microcirculation without substantial platelet-endothelial interaction. In contrast, velocity of activated platelets was decreased in all vascular segments indicating platelet margination and temporal platelet-endothelium interaction. Thrombin-activated platelets adhered to arteriolar endothelium; in capillaries and venules adherence of platelets was increased 8-fold and 13-fold, respectively. In conclusion, using intravital microscopy platelet kinetics were directly analyzed in the pulmonary microcirculation in vivo for the first time. In contrast to leukocytes, no substantial platelet-endothelium interaction occurs in the pulmonary microcirculation without any further stimulus. In response to platelet activation, molecular mechanisms enable adhesion of platelets in arterioles and venules as well as retention of platelets within capillaries. Copyright (C) 2002 S. Karger AG, Basel
Issues, challenges, and leadership qualities of participating NJAC head soccer coaches at the division III level
The purpose of this study was to identify the issues, challenges, and leadership qualities of NCAA Division III head soccer coaches in a highly competitive and diverse area of the United States. Fifteen head soccer coaches from the New Jersey Athletic Conference completed the Leadership Assessment Instrument and the Issues and Challenges survey to identify similarities amongst state institutions of higher education in New Jersey and to compare similarities between head coaches of male and female soccer programs. Findings suggest there are no distinct differences amongst these institutions or between head coaches of male and female soccer programs. The leadership competencies and skills also reveal no distinct differences between the head coaches for male soccer programs when compared to female soccer programs
Observable consequences of quantum gravity: Can light fermions exist?
Any theory of quantum gravity must ultimately be connected to observations.
This demand is difficult to be met due to the high energies at which we expect
the quantum nature of gravity to become manifest. Here we study, how viable
quantum gravity proposals can be restricted by investigating the interplay of
gravitational and matter degrees of freedom. Specifically we demand that a
valid quantum theory of gravity must allow for the existence of light (compared
to the Planck scale) fermions, since we observe these in our universe. Within
the effective theory framework, we can thus show that UV completions for
gravity are restricted, regardless of the details of the microscopic theory.
Specialising to asymptotically safe quantum gravity, we find indications that
universes with light fermions are favoured within this UV completion for
gravity.Comment: 4 pages, based on a talk given at Loops '11, Madrid, to appear in
Journal of Physics: Conference Series (JPCS
Islets of Langerhans Are Protected from Inflammatory Cell Recruitment during Reperfusion of Rat Pancreas Grafts
Background: Ischemia/reperfusion (I/R) injury plays a pivotal role in the development of graft pancreatitis, with ischemia time representing one of its crucial factors. However, it is unclear, whether exocrine and endocrine tissue experience similar inflammatory responses during pancreas transplantation (PTx). This study evaluated inflammatory susceptibilities of islets of Langerhans (ILH) and exocrine tissue after different preservation periods during early reperfusion. Methods: PTx was performed in rats following 2 h (2h-I) or 18 h (18h-I) preservation. Leukocyte-endothelial cell interactions (LEI) were analyzed in venules of acinar tissue and ILH in vivo over 2 h reperfusion. Nontransplanted animals served as controls. Tissue samples were analyzed by histomorphometry. Results: In exocrine venules leukocyte rolling predominated in the 2h-I group. In the 18h-I group, additionally, high numbers of adherent leukocytes were found. Histology revealed significant edema formation and leukocyte extravasation in the 18h-I group. Notably, LEI in postcapillary venules of ILH were significantly lower. Leukocyte rolling was only moderately enhanced and few leukocytes were found adherent. Histology revealed minor leukocyte extravasation. Conclusion: Ischemia time contributes decisively to the extent of the I/R-injury in PTx. However, ILH have a significantly lower susceptibility towards I/R, even when inflammatory reactions in adjacent exocrine tissue are evident. Copyright (C) 2010 S. Karger AG, Base
Increasing Engagement of English Learners Through Universal Design for Learning
English learners (ELs) are the fastest growing segment of K–12 students. When ELs do not respond to instruction as quickly as their English-speaking peers, teachers may focus on their deficits and wrongly label them as having a learning disability. In this article on the universal design for learning engagement guidelines, we summarize how we have anticipated learning barriers and increased engagement with academic content for ELs in our practice. By teaching strategies for self-regulation and individual coping skills, providing guided practice and support to sustain effort, and giving students various ways to achieve the same goal in a safe learning environment, teachers of ELs and collaborative staff can engage students in their classrooms and schools. We explore universal design for learning for ELs through an assets-based approach and suggest strategies for elementary and secondary teachers to modify for ELs through illustrative case vignettes based on our classroom practice
Orientation of cellulose nanocrystals in electrospun polymer fibres (dataset)
Dataset supporting the open access article.Polystyrene and poly(vinyl alcohol) nanofibres containing cellulose nanocrystals (CNCs) were successfully produced by electrospinning. Knowledge of the local orientation of CNCs in electrospun fibres is critical to understand and exploit their mechanical properties. The orientation of CNCs in these electrospun fibres was investigated using transmission electron microscopy (TEM) and Raman spectroscopy. A Raman band located at ~1095 cm−1, associated with the C–O ring stretching of the cellulose backbone, was used to quantify the orientation of the CNCs within the fibres. Raman spectra were fitted using a theoretical model to characterize the extent of orientation. From these data, it is observed that the CNCs have little orientation along the direction parallel to the axis of the fibres. Evidences for both oriented and non-oriented regions of CNCs in the fibres are presented from TEM images of nanofibres. These results contradict previously published work in this area and micromechanical modelling calculations suggest a uniform orientation of CNCs in electrospun polymer fibres. It is demonstrated that this explains why the mechanical properties of electrospun fibre mats containing CNCs are not always the same as that would be expected for a fully oriented system
Einfluß der Konservierungszeit auf die Konzentration mehrfach ungesättigter Fettsäuren in Erythrozytenkonzentraten: Implikationen für den endotoxin-induzierten akuten Lungenschaden in vivo
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