25 research outputs found
Nematic Structure of Space-Time and its Topological Defects in 5D Kaluza-Klein Theory
We show, that classical Kaluza-Klein theory possesses hidden nematic
dynamics. It appears as a consequence of 1+4-decomposition procedure, involving
4D observers 1-form \lambda. After extracting of boundary terms the, so called,
"effective matter" part of 5D geometrical action becomes proportional to square
of anholonomicity 3-form \lambda\wedge d\lambda. It can be interpreted as twist
nematic elastic energy, responsible for elastic reaction of 5D space-time on
presence of anholonomic 4D submanifold, defined by \lambda. We derive both 5D
covariant and 1+4 forms of 5D nematic equilibrium equations, consider simple
examples and discuss some 4D physical aspects of generic 5D nematic topological
defects.Comment: Latex-2e, 14 pages, 1 Fig., submitted to GR
Exterior spacetime for stellar models in 5-dimensional Kaluza-Klein gravity
It is well-known that Birkhoff's theorem is no longer valid in theories with
more than four dimensions. Thus, in these theories the effective 4-dimensional
picture allows the existence of different possible, non-Schwarzschild,
scenarios for the description of the spacetime outside of a spherical star,
contrary to general relativity in 4D. We investigate the exterior spacetime of
a spherically symmetric star in the context of Kaluza-Klein gravity. We take a
well-known family of static spherically symmetric solutions of the Einstein
equations in an empty five-dimensional universe, and analyze possible stellar
exteriors that are conformal to the metric induced on four-dimensional
hypersurfaces orthogonal to the extra dimension. All these exteriors are
continuously matched with the interior of the star. Then, without making any
assumptions about the interior solution, we prove the following statement: the
condition that in the weak-field limit we recover the usual Newtonian physics
singles out an unique exterior. This exterior is "similar" to Scharzschild
vacuum in the sense that it has no effect on gravitational interactions.
However, it is more realistic because instead of being absolutely empty, it is
consistent with the existence of quantum zero-point fields. We also examine the
question of how would the deviation from the Schwarzschild vacuum exterior
affect the parameters of a neutron star. In the context of a model star of
uniform density, we show that the general relativity upper limit M/R < 4/9 is
significantly increased as we go away from the Schwarzschild vacuum exterior.
We find that, in principle, the compactness limit of a star can be larger than
1/2, without being a black hole. The generality of our approach is also
discussed.Comment: Typos corrected. Accepted for publication in Classical and Quantum
Gravit
Algorithm for selecting predictors and prognosis of atrial fibrillation in patients with coronary artery disease after coronary artery bypass grafting
Aim. To develop an algorithm for selecting predictors and prognosis of atrial fibrillation (AF) in patients with coronary artery disease (CAD) after coronary artery bypass grafting (CABG).Material and methods. This retrospective study included 886 case histories of patients with CAD aged 35 to 81 years (median age, 63 years; 95% confidence interval [63; 64]), who underwent isolated CABG under cardiopulmonary bypass. Eighty-five patients with prior AF were excluded from the study. Two groups of persons were identified, the first of which consisted of 153 (19,1%) patients with newly recorded AF episodes, the second — 648 (80,9%) patients without cardiac arrhythmias. Preoperative clinical and functional status was assessed using 100 factors. Chi-squared, Fisher, and Mann-Whitney tests, as well as univariate logistic regression (LR) were used for data processing and analysis. Multivariate LR and artificial neural networks (ANN) were used to develop predictive models. The boundaries of significant ranges of potential predictors were determined by stepwise assessment of the odds ratio and p-value. The model accuracy was assessed using 4 metrics: area under the ROC-curve (AUC), sensitivity, specificity, and accuracy.Results. A comprehensive analysis of preoperative status of patients made it possible to identify 11 factors with the highest predictive potential, linearly and nonlinearly associated with postoperative AF (PAF). These included age (55-74 years for men and 60-78 years for women), anteroposterior and superior-inferior left atrial dimensions, transverse and longitudinal right atrial dimensions, tricuspid valve regurgitation, left ventricular end systolic dimension >49 mm, RR length of 1000-1100 ms, PQ length of 170-210 ms, QRS length of 50-80 ms, QT >420 ms for men and >440 ms for women, and heart failure with ejection fraction of 4560%. The metrics of the best predictive ANN model were as follows: AUC — 0,75, specificity — 0,73, sensitivity — 0,74, and accuracy — 0,73. These values in best model based on multivariate LR were lower (0,75; 0,7; 0,68 and 0,7, respectively).Conclusion. The developed algorithm for selecting predictors made it possible to verify significant predictive ranges and weight coefficients characterizing their influence on PAF development. The predictive model based on ANN has a higher accuracy than multivariate HR
Higher Dimensional Cylindrical or Kasner Type Electrovacuum Solutions
We consider a D dimensional Kasner type diagonal spacetime where metric
functions depend only on a single coordinate and electromagnetic field shares
the symmetries of spacetime. These solutions can describe static cylindrical or
cosmological Einstein-Maxwell vacuum spacetimes. We mainly focus on
electrovacuum solutions and four different types of solutions are obtained in
which one of them has no four dimensional counterpart. We also consider the
properties of the general solution corresponding to the exterior field of a
charged line mass and discuss its several properties. Although it resembles the
same form with four dimensional one, there is a difference on the range of the
solutions for fixed signs of the parameters. General magnetic field vacuum
solution are also briefly discussed, which reduces to Bonnor-Melvin magnetic
universe for a special choice of the parameters. The Kasner forms of the
general solution are also presented for the cylindrical or cosmological cases.Comment: 16 pages, Revtex. Text and references are extended, Published versio
Structural instability of Friedmann-Robertson-Walker cosmological models
Cosmological singularity and asymptotic behaviour of scale factor of
generalized cosmological models are analyzed in respect of their structural
stability. It is shown, that cosmological singularity is structurally unstable
for the majority of models with barotropic perfect fluid with strong energy
condition. Inclusion of Lambda-term extends the set of structurally stable
cosmological models.Comment: 14 pages, 4 figures in TeXCad, developed version of talk, presented
at XIII Russian Gravitational Conference, June 2008, to be published in GRG,
minor changes concerning added reference
The clinical relevance of oliguria in the critically ill patient : Analysis of a large observational database
Funding Information: Marc Leone reports receiving consulting fees from Amomed and Aguettant; lecture fees from MSD, Pfizer, Octapharma, 3 M, Aspen, Orion; travel support from LFB; and grant support from PHRC IR and his institution. JLV is the Editor-in-Chief of Critical Care. The other authors declare that they have no relevant financial interests. Publisher Copyright: © 2020 The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Background: Urine output is widely used as one of the criteria for the diagnosis and staging of acute renal failure, but few studies have specifically assessed the role of oliguria as a marker of acute renal failure or outcomes in general intensive care unit (ICU) patients. Using a large multinational database, we therefore evaluated the occurrence of oliguria (defined as a urine output 16 years) patients in the ICON audit who had a urine output measurement on the day of admission were included. To investigate the association between oliguria and mortality, we used a multilevel analysis. Results: Of the 8292 patients included, 2050 (24.7%) were oliguric during the first 24 h of admission. Patients with oliguria on admission who had at least one additional 24-h urine output recorded during their ICU stay (n = 1349) were divided into three groups: transient - oliguria resolved within 48 h after the admission day (n = 390 [28.9%]), prolonged - oliguria resolved > 48 h after the admission day (n = 141 [10.5%]), and permanent - oliguria persisting for the whole ICU stay or again present at the end of the ICU stay (n = 818 [60.6%]). ICU and hospital mortality rates were higher in patients with oliguria than in those without, except for patients with transient oliguria who had significantly lower mortality rates than non-oliguric patients. In multilevel analysis, the need for RRT was associated with a significantly higher risk of death (OR = 1.51 [95% CI 1.19-1.91], p = 0.001), but the presence of oliguria on admission was not (OR = 1.14 [95% CI 0.97-1.34], p = 0.103). Conclusions: Oliguria is common in ICU patients and may have a relatively benign nature if only transient. The duration of oliguria and need for RRT are associated with worse outcome.publishersversionPeer reviewe