A Clinical Profile of Hepatitis a Patients in Jakarta, Indonesia

Background: To determine the incidence of hepatitis A infections and the clinical profiles of adult patients admitted to public hospitals in Jakarta, Indonesia. Methods: This was a cross-sectional study that utilised consecutive secondary data from internal medicine wards of seven public hospitals in Jakarta between 2011 and 2013. Eligibility criteria included patients over the age of 18 years and an ICD-10 diagnosis code of B15, acute hepatitis A. Case proportion was reported per 1000 people by dividing incidence per year to total in-ward patients. Clinical profiles were reported descriptively. Laboratory results were compared and categorised into groups of patients aged below and above 25 years old. Results: Data revealed that hospitalisations of patients with hepatitis A had decreased from 2011 to 2013. 289 patients were studied, the majority were young adults (18-25 years old) and their common chief complaints were nausea (36%), fever (24%), and jaundice (21%). Higher bilirubin levels were seen in older patients. There were 13 patients coinfected with hepatitis B, one patient coinfected with hepatitis C, and one patient coinfected with HIV. Conclusions: The proportion of hepatitis A infection amongst adults admitted to public hospitals in Jakarta was low and had decreased during the study period. Most of the patients reported classical clinical manifestations. This study found that the targeted age group may benefit from receiving routine hepatitis A vaccinations

Aerosol light-scattering enhancement due to water uptake during the TCAP campaign

Aerosol optical properties were measured by the DOE/ARM (US Department of Energy Atmospheric Radiation Measurements) Program Mobile Facility during the Two-Column Aerosol Project (TCAP) campaign deployed at Cape Cod, Massachusetts, for a 1-year period (from summer 2012 to summer 2013). Measured optical properties included aerosol light-absorption coefficient (σap) at low relative humidity (RH) and aerosol light-scattering coefficient (σsp) at low and at RH values varying from 30 to 85%, approximately. Calculated variables included the single scattering albedo (SSA), the scattering Ångström exponent (SAE) and the scattering enhancement factor (f(RH)). Over the period of measurement, f(RH = 80%) had a mean value of 1.9 ± 0.3 and 1.8 ± 0.4 in the PM10 and PM1 fractions, respectively. Higher f(RH = 80%) values were observed for wind directions from 0 to 180° (marine sector) together with high SSA and low SAE values. The wind sector from 225 to 315° was identified as an anthropogenically influenced sector, and it was characterized by smaller, darker and less hygroscopic aerosols. For the marine sector, f(RH = 80%) was 2.2 compared with a value of 1.8 obtained for the anthropogenically influenced sector. The air-mass backward trajectory analysis agreed well with the wind sector analysis. It shows low cluster to cluster variability except for air masses coming from the Atlantic Ocean that showed higher hygroscopicity. Knowledge of the effect of RH on aerosol optical properties is of great importance for climate forcing calculations and for comparison of in situ measurements with satellite and remote sensing retrievals. In this sense, predictive capability of f(RH) for use in climate models would be enhanced if other aerosol parameters could be used as proxies to estimate hygroscopic growth. Toward this goal, we propose an exponential equation that successfully estimates aerosol hygroscopicity as a function of SSA at Cape Cod. Further work is needed to determine if the equation obtained is valid in other environments.This research was funded by the NOAA Climate Program using measurements funded by the US Department of Energy Atmospheric System Research program. The authors would like to express their gratitude to the NOAA Air Resources Laboratory (ARL) for the provision of the HYSPLIT transport and dispersion model. We would like to thank also the Openair project. G. Titos was funded by the Spanish Ministry of Economy and Competitiveness – Secretariat of Science, Innovation and Development under grants BES-2011-043721 and EEBB-I-13-06456, and projects P10-RNM-6299, CGL2010-18782 and EU INFRA-2010-1.1.16-262254

Way Combination for an Adaptive and Scalable Coherence Directory

© 2019 IEEE. Personal use of this material is permitted. Permissíon from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertisíng or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.[EN] This manuscript opens the way to a new class of coherence directory structures that are based on the brand-new concept of way combining. A Way-Combining Directory (WC-dir) builds on a typical sparse directory but allows to take advantage of several ways in the same set to codify the sharing information of each memory block. The result is a sparse directory with variable effective associativity per set and variable length entries, thus being able to dynamically adapt the directory structure to the particular requirements of each application. In particular, our proposal uses just enough bits per entry to store a single pointer, which is optimal for the common case of having just one sharer. For those addresses that have more than one sharer, we have observed that in the majority of cases extra bits could be taken from other empty ways in the same set. All in all, our proposal minimizes the storage overheads without losing the flexibility to adapt to several sharing degrees and without the complexities of other previously proposed techniques. Detailed simulations of a 128-core multicore architecture running benchmarks from PARSEC-3.0 and SPLASH-3 demonstrate that WC-dir can closely approach the performance of a non-scalable bit vector sparse directory, beating the state-of-the-art Scalable Coherence Directory (SCD) and Pool directory proposals.This work has been supported by the Spanish MCIU and AEI, as well as European Commission FEDER funds, under grant "RTI2018-098156-B-C53".Titos-Gil, R.; Flores, A.; Fernández-Pascual, R.; Ros, A.; Petit Martí, SV.; Sahuquillo Borrás, J.; Acacio, ME. (2019). Way Combination for an Adaptive and Scalable Coherence Directory. IEEE Transactions on Parallel and Distributed Systems. 30(11):2608-2623. https://doi.org/10.1109/TPDS.2019.2917185S26082623301

Hardware transactional memory with software-defined conflicts

In this paper we propose conflict-defined blocks, a programming language construct that allows programmers to change the concept of conflict from one transaction to another, or even throughout the course of the same transaction. Defining conflicts in software makes possible the removal of dependencies which, though not necessary for the correct execution of the transactions, arise as a result of the coarse synchronization style encouraged by TM. Programmers take advantage of their knowledge about the problem and specify through confict-defined blocks what types of dependencies are superfluous in a certain part of the transaction, in order to extract more performance out of coarse-grained transactions without having to write minimally synchronized code. Our experiments with several transactional benchmarks reveal that using software-defined conflicts, the programmer achieves significant reductions in the number of aborted transactions and improve scalability.Peer ReviewedPostprint (author's final draft

The Impact of Non-coherent Buffers on Lazy Hardware Transactional Memory Systems

Abstract When supported in silicon, transactional memory (TM

Spatial and temporal variability of carbonaceous aerosols: assessing the impact of biomass burning in the urban environment

Biomass burning (BB) is a significant source of atmospheric particles in many parts of the world. Whereas many studies have demonstrated the importance of BB emissions in central and northern Europe, especially in rural areas, its impact in urban air quality of southern European countries has been sparsely investigated. In this study, highly time resolved multi-wavelength absorption coefficients together with levoglucosan (BB tracer) mass concentrations were combined to apportion carbonaceous aerosol sources. The Aethalometer model takes advantage of the different spectral behaviour of BB and fossil fuel (FF) combustion aerosols. The model was found to be more sensitive to the assumed value of the aerosol Ångström exponent (AAE) for FF (AAEff) than to the AAE for BB (AAEbb). As result of various sensitivity tests the model was optimized with AAEff = 1.1 and AAEbb = 2. The Aethalometer model and levoglucosan tracer estimates were in good agreement. The Aethalometer model was further applied to data from three sites in Granada urban area to evaluate the spatial variation of CMff and CMbb (carbonaceous matter from FF or BB origin, respectively) concentrations within the city. The results showed that CMbb was lower in the city centre while it has an unexpected profound impact on the CM levels measured in the suburbs (about 40%). Analysis of BB tracers with respect to wind speed suggested that BB was dominated by sources outside the city, to the west in a rural area. Distinguishing whether it corresponds to agricultural waste burning or with biomass burning for domestic heating was not possible. This study also shows that although traffic restrictions measures contribute to reduce carbonaceous concentrations, the extent of the reduction is very local. Other sources such as BB, which can contribute to CM as much as traffic emissions, should be targeted to reduce air pollution.This research was partially supported by the Andalusia Regional Government through projects P10-RNM-6299 and P12-RNM-2409, by the Spanish Ministry of Economy and Competitiveness and FEDER through project CGL2013_45410-R; by EUREKA and the Slovenian Ministry of Economic Development and Technology grants (Eurostars grant E!4825 FC Aeth, JR-KROP grant 3211-11-000519); and by European Union's Horizon 2020 Research and Innovation Programme under grant agreement No. 654109, ACTRIS-2. The authors would like to thank Air Quality Service from Junta de Andalucía (Consejería de Medio Ambiente y Ordenación del Territorio) and Vicerrectorado de Política Científica e Investigación from the University of Granada for their support in the installation of the Aethalometer at PC and GV, respectively.G. Titos was partially funded by Programa del Plan Propio de Investigación “Contrato Puente” of the University of Granada and by the Spanish Ministry of Economy and Competitiveness under postdoctoral program Juan de la Cierva – Formación (FJCI-2014-20819)

Proyecto Tetris: aprendizaje de la programación en ensamblador por piezas

El aprendizaje del lenguaje ensamblador constituye con frecuencia uno de los objetivos formativos de alguna de las primeras asignaturas de Arquitectura de Computadores del Grado en Ingeniería Informática. Si bien el desarrollo y la depuración de programas en lenguaje ensamblador resultan esenciales para ayudar a comprender el funcionamiento básico de un procesador, son aspectos que presentan especial dificultad y/o falta de atractivo para el alumnado. En este trabajo presentamos nuestra experiencia con la enseñanza del lenguaje ensamblador MIPS a través de la codificación del videojuego Tetris. El proyecto Tetris se desarrolla en el contexto de una asignatura de primer curso y segundo cuatrimestre. Para que resulte asequible a este nivel, se proporciona al alumno una versión incompleta del programa, que habrá de completar mediante la traducción directa a ensamblador de funciones escritas en lenguaje C (también proporcionadas), y mediante la codificación del resto de la funcionalidad directamente en ensamblador. El resultado es una versión del juego plenamente operativa. El desarrollo se realiza utilizando una versión extendida del simulador MARS. Los resultados obtenidos por los alumnos muestran que este proyecto les facilita el aprendizaje del ensamblador, pues el 85.6% de los que superan el proyecto Tetris aprueban también el examen de prácticas.Learning assembly language represents typically one of the formative objectives of some of the first courses related to computer architecture in Computer Engineering degrees. Although the development and debugging of programs written in assembly language are essential to help students understand the basic operation of a processor, they are also aspects that present special difficulty and/or lack of attractiveness for students. In this work we present our experience in the teaching of the MIPS assembly language through the coding of the videogame Tetris. The Tetris project is developed in the context of a first-year and second-term course. In order to be affordable at this level, the student is provided with an incomplete version of the program, which must be completed through the direct translation to the MIPS assembly language of functions written in the C language (also provided), and through the implementation of additional functionality directly in assembly language. The result is a fully operational version of the game. The development is done using an extended version of the MARS simulator. The results obtained by the students show that this project facilitates the learning of the assembly, since 85.6% of those who pass the Tetris project also pass the practicum exam

The REDMAAS 2014 intercomparison campaign: CPC, SMPS, UFPM and neutralizers

Ponencia presentada en:2nd Iberian Meeting on Aerosol Science and Technology (RICTA 2014) celebrado en Tarragona del 7 al 9 de julio de 2014.The Spanish network on environmental DMAs (Red Española de DMAs Ambientales, REDMAAS), working since 2010, is currently formed by six groups involved in the measurement of atmospheric aerosol size distributions by means of Differential Mobility Analyzers (DMAs). One of its activities is an annual intercomparison of mobility size spectrometers (SMPS and UFPM). In this work we show the results obtained in the 2014 campaign: the verification of DMA calibrations with latex, the results of the CPC and SMPS + UFPM intercomparisons, and a comparison of the new TSI 3087 X-ray and the former TSI 3077 85Kr neutralizers. The concentrations measured by different types of CPC were within the range of 10% of the average value. CPCs working at higher flow rates measured slightly higher concentrations, probably related to the smaller losses in the lines. All the SMPS worked at the same sampling and sheath flow rates (1:10 lpm). Four of the SMPS gave very good results for particles larger than 20 nm. The UFPM measured particle number concentrations in the average +/-10% band measured by the SMPS. Instruments working with the X-ray neutralizer measured higher concentrations than with the 85Kr neutralizers. This could mean that particle losses are smaller inside this neutralizer.This work has been financed by the Ministry of Science and Innovation (CGL2011-15008-E, CGL2010-1777, CGL2011-27020 & CGL2011-26259)

Effect of hygroscopic growth on the aerosol light-scattering coefficient: A review of measurements, techniques and error sources

Knowledge of the scattering enhancement factor, f(RH), is important for an accurate description of direct aerosol radiative forcing. This factor is defined as the ratio between the scattering coefficient at enhanced relative humidity, RH, to a reference (dry) scattering coefficient. Here, we review the different experimental designs used to measure the scattering coefficient at dry and humidified conditions as well as the procedures followed to analyze the measurements. Several empirical parameterizations for the relationship between f(RH) and RH have been proposed in the literature. These parameterizations have been reviewed and tested using experimental data representative of different hygroscopic growth behavior and a new parameterization is presented. The potential sources of error in f(RH) are discussed. A Monte Carlo method is used to investigate the overall measurement uncertainty, which is found to be around 20 e40% for moderately hygroscopic aerosols. The main factors contributing to this uncertainty are the uncertainty in RH measurement, the dry reference state and the nephelometer uncertainty. A literature survey of nephelometry-based f(RH) measurements is presented as a function of aerosol type. In general, the highest f(RH) values were measured in clean marine environments, with pollution having a major influence on f(RH). Dust aerosol tended to have the lowest reported hygroscopicity of any of the aerosol types studied. Major open questions and suggestions for future research priorities are outlined.This work was supported by the Andalusia Regional Government through projects P10-RNM-6299 and P12-RNM-2409; by the Spanish Ministry of Economy and Competitiveness and FEDER through project CGL2013_45410-R; and by European Union’s Horizon 2020 research and innovation programme under grant agreement No 654109, ACTRIS-2. G. Titos was partially funded by Programa del Plan Propio de Investigación “Contrato Puente” of the University of Granada. We thank the Stockholm International Meteorological Institute (IMI) for travel support of G. Titos

TEMPORAL AND SPATIAL VARIABILITY OF ATMOSPHERIC PARTICLE NUMBER SIZE DISTRIBUTIONS ACROSS SPAIN

This study synthesizes for the first time results from simultaneous aerosol measurements performed at seven diverse locations distributed all over the Spanish geography. The observations were carried out during two field campaigns in 2012–2013, one-month each and during different seasons. These field campaigns were performed in the framework of the Spanish Network of DMAs (REDMAAS) activities. Measurement sites were grouped as polluted sites (urban background) and clean sites (rural background and high-altitude sites). Seasonal differences were more important at polluted sites, mainly related to meteorology and aerosol sources. Higher total particle concentrations were found during the cold period, driven mainly by Aitken-mode particles (traffic-related aerosol particles).This work has been financed by the Ministry of Science and Innovation (CGL2011-15008-E, CGL2010-1777, CGL2011-27020, CGL2014-52877-R, CGL2010-11095-E, CGL2012-39623-C02-01, CGL2014-55230-R & PI15/0051