Bomen over ruimte: een studie naar de toekomstige ruimtebehoefte voor de boomteelt in de regio Boskoop

In het kader van de streekplanherziening Zuid-Holland Oost is een schatting gemaakt van de toekomstige ruimtebehoefte voor de boomteelt in de regio Boskoop tot 2015. Op basis van toekomstige ontwikkelingen in de vraag naar boomteeltproducten, de (inter)nationale concurrentiepositie van de boomteelt in de regio Boskoop en de bedrijfsstructuur is de extra ruimtebehoefte geschat op 2% per jaar. Het totale areaal boomteelt in 2015 komt hiermee op 1.435 ha (+ 335 ha), waarvan de helft pot- en containerteelt en de helft in de vollegrond. Ook zal tot 2015 de teelt onder glas gestaag toenemen. Om het boomteeltcentrum in de regio Boskoop in stand te houden is niet alleen behoefte aan extra ruimte, maar zal ook voldaan moeten worden aan een aantal kwalitatieve randvoorwaarden. De belangrijkste randvoorwaarden zijn: planologische zekerheid, ruimte voor ondersteunend glas, goede bedrijfsstructuur, goede infrastructuur, kwalitatief goed opgeleid personeel en professioneel ondernemersscha

Investeren in competenties; een onderzoek in de Greenports

Inventarisatie van de huidige en toekomstige vraag/behoeftes aan competenties bij ondernemers, managers en werknemers in het tuinbouwcluste

Imaging dielectric relaxation in nanostructured polymers by frequency modulation electrostatic force microscopy

We have developed a method for imaging the temperature-frequency dependence of the dynamics of nanostructured polymer films with spatial resolution. This method provides images with dielectric compositional contrast well decoupled from topography. Using frequency-modulation electrostatic-force-microscopy, we probe the local frequency-dependent (0.1–100 Hz) dielectric response through measurement of the amplitude and phase of the force gradient in response to an oscillating applied electric field. When the phase is imaged at fixed frequency, it reveals the spatial variation in dielectric losses, i.e., the spatial variation in molecular/dipolar dynamics, with 40 nm lateral resolution. This is demonstrated by using as a model system; a phase separated polystyrene/polyvinyl-acetate (PVAc) blend. We show that nanoscale dynamic domains of PVAc are clearly identifiable in phase images as those which light-up in a band of temperature, reflecting the variations in the molecular/dipolar dynamics approaching the glass transition temperature of PVAc

Boskoop en Bollenstreek. Hoe innig is de samenwerking

In het kader van de streekplanherziening Zuid-Holland Oost is in opdracht van de provincie Zuid-Holland onderzoek gedaan naar de autonome ontwikkeling van het boomteeltcomplex Boskoop en de interacties met het bloembollencomplex 'De Bollenstreek'. Om het belang van het boomteeltcomplex binnen het sierteeltcomplex Zuid-Holland te duiden zijn ook de interacties met de bloemisterij in kaart gebracht. De interacties tussen Boskoop en de Bollenstreek blijven beperkt tot een gecombineerde afzet van bloembollen en een beperkt assortiment boomteeltproducten, met name vaste planten. Mede door het groeiende belang van de bloemenveilingen in de afzet van boomteeltproducten en de toenemende vraag naar visueel aantrekkelijke boomteeltproducten is de interactie tussen Boskoop en het bloemisterijcomplex Zuid-Holland veel sterker. Vanwege de aanwezigheid van een groot assortiment aan boomteeltproducten, de beschikbaarheid van veel kennis en vakmanschap, korte transportlijnen naar de veilingen en de centrale ligging heeft Boskoop een belangrijke meerwaarde binnen het sierteeltcomplex Zuid-Holland

The effect of the apolipoprotein E phenotype on plasma lipids is not influenced by environmental variability: results of a Dutch twin study

We tested the influence of the apolipoprotein E (apoE) polymorphism on the intrapair differences in the levels of plasma cholesterol, plasma triglycerides, low density lipoprotein-cholesterol, apoB and apoE in monozygotic (MZ) twins, and estimated whether or not there was a interaction between the apoE polymorphism and environmental factors. In 65 MZ twin pairs, the intrapair differences in the measured lipoprotein parameters were similar in the different apoE phenotype classes. This indicates that the effect of the apoE polymorphism is not influenced by environmental variability between the MZ pair members and accordingly identifies the APOE gene as a "level" gene. © 1993 Springer-Verlag

Genetic variants determining survival and fertility in an adverse African environment:a population-based large-scale candidate gene association study

Molecular Technology and Informatics for Personalised Medicine and Healt

The Dutch Y-chromosomal landscape

Previous studies indicated existing, albeit limited, genetic-geographic population substructure in the Dutch population based on genome-wide data and a lack of this for mitochondrial SNP based data. Despite the aforementioned studies, Y-chromosomal SNP data from the Netherlands remain scarce and do not cover the territory of the Netherlands well enough to allow a reliable investigation of genetic-geographic population substructure. Here we provide the first substantial dataset of detailed spatial Y-chromosomal haplogroup information in 2085 males collected across the Netherlands and supplemented with previously published data from northern Belgium. We found Y-chromosomal evidence for genetic-geographic population substructure, and several Y-haplogroups demonstrating significant clinal frequency distributions in different directions. By means of prediction surface maps we could visualize (complex) distribution patterns of individual Y-haplogroups in detail. These results highlight the value of a micro-geographic approach and are of great use for forensic and epidemiological investigations and our understanding of the Dutch population history. Moreover, the previously noted absence of genetic-geographic population substructure in the Netherlands based on mitochondrial DNA in contrast to our Y-chromosome results, hints at different population histories for women and men in the Netherlands.Molecular Technology and Informatics for Personalised Medicine and Healt

Subdividing Y-chromosome haplogroup R1a1 reveals Norse Viking dispersal lineages in Britain

The influence of Viking-Age migrants to the British Isles is obvious in archaeological and place-names evidence, but their demographic impact has been unclear. Autosomal genetic analyses support Norse Viking contributions to parts of Britain, but show no signal corresponding to the Danelaw, the region under Scandinavian administrative control from the ninth to eleventh centuries. Y-chromosome haplogroup R1a1 has been considered as a possible marker for Viking migrations because of its high frequency in peninsular Scandinavia (Norway and Sweden). Here we select ten Y-SNPs to discriminate informatively among hg R1a1 sub-haplogroups in Europe, analyse these in 619 hg R1a1 Y chromosomes including 163 from the British Isles, and also type 23 short-tandem repeats (Y-STRs) to assess internal diversity. We find three specifically Western-European sub-haplogroups, two of which predominate in Norway and Sweden, and are also found in Britain; starlike features in the STR networks of these lineages indicate histories of expansion. We ask whether geographical distributions of hg R1a1 overall, and of the two sub-lineages in particular, correlate with regions of Scandinavian influence within Britain. Neither shows any frequency difference between regions that have higher (≥10%) or lower autosomal contributions from Norway and Sweden, but both are significantly overrepresented in the region corresponding to the Danelaw. These differences between autosomal and Y-chromosomal histories suggest either male-specific contribution, or the influence of patrilocality. Comparison of modern DNA with recently available ancient DNA data supports the interpretation that two sub-lineages of hg R1a1 spread with the Vikings from peninsular Scandinavia

Crucial factors preceding compulsory psychiatric admission

BACKGROUND: Compulsory admissions have a strong effect on psychiatric patients and represent a deprivation of personal liberty. Although the rate of such admissions is tending to rise in several Western countries, there is little qualitative research on the mental health-care process preceding compulsory admission. The objective of the study was to identify crucial factors in the mental health-care process preceding compulsory admission of adult psychiatric patients. METHODS: This retrospective, qualitative multiple-case study was based on the patient records of patients with severe mental illness, mainly schizophrenia and other psychotic disorders. Twenty two patient records were analyzed. Patients' demographic and clinical characteristics were heterogeneous. All were treated by Flexible Assertive Community Treatment teams (FACT teams) at two mental health institutions in the greater Rotterdam area in the Netherlands and had a compulsory admission in a predefined inclusion period. The data were analyzed according to the Prevention and Recovery System for Monitoring and Analysis (PRISMA) method, assessing acts, events, conditions, and circumstances, failing protective barriers and protective recovery factors. RESULTS: The most important patient factors in the process preceding compulsory admission were psychosis, aggression, lack of insight, care avoidance, and unauthorized reduction or cessation of medication. Neither were health-care professionals as assertive as they could be in managing early signs of relapse and care avoidance of these particular patients. CONCLUSION: The health-care process preceding compulsory admission is complex, being influenced by acts, events, conditions and circumstances, failing barriers, and protective factors. The most crucial factors are patients' lack of insight and cessation of medication, and health-care professionals' lack of assertiveness