913 research outputs found
Remote manipulator dynamic simulation
A simulator to generate the real time visual scenes required to perform man in the loop investigations of remote manipulator application and design concepts for the space shuttle is described. The simulated remote manipulator consists of a computed display system that uses a digital computer, the electronic scene generator, an operator's station, and associated interface hardware. A description of the capabilities of the implemented simulation is presented. The mathematical models and programs developed for the simulation are included
Effective Temperature in an Interacting, Externally Driven, Vertex System: Theory and Experiment on Artificial Spin Ice
Frustrated arrays of interacting single-domain nanomagnets provide important
model systems for statistical mechanics, because they map closely onto
well-studied vertex models and are amenable to direct imaging and custom
engineering. Although these systems are manifestly athermal, we demonstrate
that the statistical properties of both hexagonal and square lattices can be
described by an effective temperature based on the magnetostatic energy of the
arrays. This temperature has predictive power for the moment configurations and
is intimately related to how the moments are driven by an oscillating external
field.Comment: 17 pages, 4 figure
Direct entropy determination and application to artificial spin ice
From thermodynamic origins, the concept of entropy has expanded to a range of
statistical measures of uncertainty, which may still be thermodynamically
significant. However, laboratory measurements of entropy continue to rely on
direct measurements of heat. New technologies that can map out myriads of
microscopic degrees of freedom suggest direct determination of configurational
entropy by counting in systems where it is thermodynamically inaccessible, such
as granular and colloidal materials, proteins and lithographically fabricated
nanometre-scale arrays. Here, we demonstrate a conditional-probability
technique to calculate entropy densities of translation-invariant states on
lattices using limited configuration data on small clusters, and apply it to
arrays of interacting nanometre-scale magnetic islands (artificial spin ice).
Models for statistically disordered systems can be assessed by applying the
method to relative entropy densities. For artificial spin ice, this analysis
shows that nearest-neighbour correlations drive longer-range ones.Comment: 10 page
Abundance of ACVR1B transcript is elevated during septic conditions: perspectives obtained from a hands-on reductionist investigation
Sepsis is a complex heterogeneous condition, and the current lack of effective risk and outcome predictors hinders the improvement of its management. Using a reductionist approach leveraging publicly available transcriptomic data, we describe a knowledge gap for the role of ACVR1B (activin A receptor type 1B) in sepsis. ACVR1B, a member of the transforming growth factor-beta (TGF-beta) superfamily, was selected based on the following: 1) induction upon in vitro exposure of neutrophils from healthy subjects with the serum of septic patients (GSE49755), and 2) absence or minimal overlap between ACVR1B, sepsis, inflammation, or neutrophil in published literature. Moreover, ACVR1B expression is upregulated in septic melioidosis, a widespread cause of fatal sepsis in the tropics. Key biological concepts extracted from a series of PubMed queries established indirect links between ACVR1B and "cancer", "TGF-beta superfamily", "cell proliferation", "inhibitors of activin", and "apoptosis". We confirmed our observations by measuring ACVR1B transcript abundance in buffy coat samples obtained from healthy individuals (n=3) exposed to septic plasma (n = 26 melioidosis sepsis cases)ex vivo. Based on our re-investigation of publicly available transcriptomic data and newly generated ex vivo data, we provide perspective on the role of ACVR1B during sepsis. Additional experiments for addressing this knowledge gap are discussed
At-home blood collection and stabilization in high temperature climates using home RNA
Expanding whole blood sample collection for transcriptome analysis beyond traditional phlebotomy clinics will open new frontiers for remote immune research and telemedicine. Determining the stability of RNA in blood samples exposed to high ambient temperatures (\u3e30°C) is necessary for deploying home-sampling in settings with elevated temperatures (e.g., studying physiological response to natural disasters that occur in warm locations or in the summer). Recently, we have develope
Beam energy dependent two-pion interferometry and the freeze-out eccentricity of pions in heavy ion collisions at STAR
We present results of analyses of two-pion interferometry in Au+Au collisions
at = 7.7, 11.5, 19.6, 27, 39, 62.4 and 200 GeV measured in the
STAR detector as part of the RHIC Beam Energy Scan program. The extracted
correlation lengths (HBT radii) are studied as a function of beam energy,
azimuthal angle relative to the reaction plane, centrality, and transverse mass
() of the particles. The azimuthal analysis allows extraction of the
eccentricity of the entire fireball at kinetic freeze-out. The energy
dependence of this observable is expected to be sensitive to changes in the
equation of state. A new global fit method is studied as an alternate method to
directly measure the parameters in the azimuthal analysis. The eccentricity
shows a monotonic decrease with beam energy that is qualitatively consistent
with the trend from all model predictions and quantitatively consistent with a
hadronic transport model.Comment: 27 pages; 27 figure
Isolation of Flow and Nonflow Correlations by Two- and Four-Particle Cumulant Measurements of Azimuthal Harmonics in 200 GeV Au+Au Collisions
A data-driven method was applied to measurements of Au+Au collisions at
200 GeV made with the STAR detector at RHIC to isolate
pseudorapidity distance -dependent and -independent
correlations by using two- and four-particle azimuthal cumulant measurements.
We identified a component of the correlation that is -independent,
which is likely dominated by anisotropic flow and flow fluctuations. It was
also found to be independent of within the measured range of
pseudorapidity . The relative flow fluctuation was found to be for particles of transverse momentum
less than GeV/. The -dependent part may be attributed to
nonflow correlations, and is found to be relative to the
flow of the measured second harmonic cumulant at
- …