2,014 research outputs found
A multi-criteria port suitability assessment for developments in the offshore wind industry
This paper investigates the logistics capabilities of offshore wind ports, namely physical characteristics, connectivity and layout of the port, for supporting the installation and operation and maintenance phases of offshore wind projects. The relative significance of these criteria is determined using the Analytical Hierarchy Process (AHP). The AHP methodology is then applied in a case study as a decision-making tool to enable decision makers to assess the suitability of a number of ports for an offshore wind farm located off the North Sea coast of the United Kingdom (UK)
Passive, broadband and low-frequency suppression of laser amplitude noise to the shot-noise limit using hollow-core fibre
We use hollow-core fibre to preserve the spectrum and temporal profile of
picosecond laser pulses in CBD to suppress 2.6 dB of amplitude noise at MHz
noise frequencies, to within 0.01 dB of the shot-noise limit. We provide an
enhanced version of the CBD scheme that concatenates circuits to suppress over
multiple frequencies and over broad frequency ranges --- we perform a first
demonstration that reduces total excess amplitude noise, between 2 - 6 MHz, by
85%. These demonstrations enable passive, broad-band, all-guided fibre laser
technology operating at the shot-noise limit.Comment: 8 pages, 8 figure
Hospital-Based Acute Care Use in Survivors of Septic Shock
OBJECTIVES: Septic shock is associated with increased long-term morbidity and mortality. However, little is known about the use of hospital-based acute care in survivors after hospital discharge. The objectives of the study were to examine the frequency, timing, causes, and risk factors associated with emergency department visits and hospital readmissions within 30 days of discharge.
DESIGN: Retrospective cohort study.
SETTING: Tertiary, academic hospital in the United States.
PATIENTS: Patients admitted with septic shock (serum lactate ≥ 4 mmol/L or refractory hypotension) and discharged alive to a nonhospice setting between 2007 and 2010.
INTERVENTIONS: None.
MEASUREMENTS AND MAIN RESULTS: The coprimary outcomes were all-cause hospital readmission and emergency department visits (treat-and-release encounters) within 30 days to any of the three health system hospitals. Of 269 at-risk survivors, 63 (23.4%; 95% CI, 18.2-28.5) were readmitted within 30 days of discharge and another 12 (4.5%; 95% CI, 2.3-7.7) returned to the emergency department for a treat-and-release visit. Readmissions occurred within 15 days of discharge in 75% of cases and were more likely in oncology patients (p=0.001) and patients with a longer hospital length of stay (p=0.04). Readmissions were frequently due to another life-threatening condition and resulted in death or discharge to hospice in 16% of cases. The reasons for readmission were deemed potentially related to the index septic shock hospitalization in 78% (49 of 63) of cases. The most common cause was infection related, accounting for 46% of all 30-day readmissions, followed by cardiovascular or thromboembolic events (18%).
CONCLUSIONS: The use of hospital-based acute care appeared to be common in septic shock survivors. Encounters often led to readmission within 15 days of discharge, were frequently due to another acute condition, and appeared to result in substantial morbidity and mortality. Given the potential public health implications of these findings, validation studies are needed
Boundaries of Semantic Distraction: Dominance and Lexicality Act at Retrieval
Three experiments investigated memory for semantic information with the goal of determining boundary conditions for the manifestation of semantic auditory distraction. Irrelevant speech disrupted the free recall of semantic category-exemplars to an equal degree regardless of whether the speech coincided with presentation or test phases of the task (Experiment 1) and occurred regardless of whether it comprised random words or coherent sentences (Experiment 2). The effects of background speech were greater when the irrelevant speech was semantically related to the to-be-remembered material, but only when the irrelevant words were high in output dominance (Experiment 3). The implications of these findings in relation to the processing of task material and the processing of background speech is discussed
Formulation and solution of a two-stage capacitated facility location problem with multilevel capacities
In this paper, the multi-product facility location problem in a two-stage supply chain is investigated. In this problem, the locations of depots (distribution centres) need to be determined along with their corresponding capacities. Moreover, the product flows from the plants to depots and onto customers must also be optimised. Here, plants have a production limit whereas potential depots have several possible capacity levels to choose from, which are defined as multilevel capacities. Plants must serve customer demands via depots. Two integer linear programming (ILP) models are introduced to solve the problem in order to minimise the fixed costs of opening depots and transportation costs. In the first model, the depot capacity is based on the maximum number of each product that can be stored whereas in the second one, the capacity is determined by the size (volume) of the depot. For large problems, the models are very difficult to solve using an exact method. Therefore, a matheuristic approach based on an aggregation approach and an exact method (ILP) is proposed in order to solve such problems. The methods are assessed using randomly generated data sets and existing data sets taken from the literature. The solutions obtained from the computational study confirm the effectiveness of the proposed matheuristic approach which outperforms the exact method. In addition, a case study arising from the wind energy sector in the UK is presented
Pre-cooling for endurance exercise performance in the heat: a systematic review.
PMCID: PMC3568721The electronic version of this article is the complete one and can be found online at: http://www.biomedcentral.com/1741-7015/10/166.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Endurance exercise capacity diminishes under hot environmental conditions. Time to exhaustion can be increased by lowering body temperature prior to exercise (pre-cooling). This systematic literature review synthesizes the current findings of the effects of pre-cooling on endurance exercise performance, providing guidance for clinical practice and further research
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