112 research outputs found

    5-10 Yaş Arası Çocuk Tüketicilerin Giysi Tercihleri ve Giysi Satın Alma Davranışlarına Etki Eden Faktörler

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    Kişilerin tüketici olarak sosyalleşmesi çocukluk dönemlerinde başlar. Çocuklar, küçük yaşlardan itibaren ailelerinin satın alma kararlarını etkileyebilmektedir. Bu araştırmanın amacı, 5-10 yaş aralığındaki çocukların giysi tercihleri ve giysi satın alma davranışlarına etki eden faktörleri belirlemektir. Betimsel araştırma yönteminin kullanıldığı çalışmanın evrenini Edirne merkezdeki farklı sosyo-ekonomik duruma sahip 6 devlet okulunda öğrenim gören 5-10 yaş arası çocuk tüketicilerin aileleri; örneklemini bu okullardan gelişigüzel olarak seçilen 667 öğrenci velisi oluşturmaktadır. Araştırmada veri toplama aracı olarak anket formu kullanılmış, sorular Engel, Kollat ve Blackwell (EKB) tüketici davranış modeline uygun olarak 4 ana bölümde yapılandırılmıştır. Elde edilen veriler SPSS programına aktarılmış, bulgular cinsiyet değişkeni dikkate alınarak çapraz tablolarda verilmiştir. Cinsiyete göre verilen cevapların arasındaki istatistiksel ilişkinin ölçümü için ki-kare ilişki analizi yapılmıştır. Araştırmaya göre çocuk tüketicilerde, giysinin fiziksel olarak vücuda uygunluğu, modeli, kalitesi her iki cinsiyet açısından da her zaman dikkat edilen özellikler olduğu ve çocukların beğendikleri giysi olduğunda mutlaka belli ettikleri saptanmıştır. Çocukların marka konusunda ısrarcı olmadıkları sonucu da dikkat çekicidir

    Optimization Of Human Lysozyme Production From Acid Whey (Poster - Abstract Only)

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    Acid whey is a byproduct from the production of fermented dairy products, such as Greek yogurt and sour cream. The sharp increase in consumption of Greek-style yogurt in recent years has challenged dairy producers in terms of what to do with large volume of acid whey as the waste. Acid whey contains far less lactose than sweet whey and has therefore been mostly overlooked in terms of concentrating or utilizing its nutrients for secondary use. This study aimed to utilize acid whey for the production of value-added product, human lysozyme, which has many applications as antimicrobial compound in food and pharmaceutical industries. In the first phase of the study, the effect of sterilization process on human lysozyme production by Kluyveromyces lactis K7 was evaluated. No significant difference has been found in the production of human lysozyme in sterile acid whey and non-sterile acid whey (p>0.005). Then, to find the optimum combination of nutrient supplementation need to maximize the human lysozyme production, three factors Box-Behnken design was used and different concentrations of lactose (0-13 % w/v), yeast nitrogen base (0-1.5 % w/v), and casamino acid supplementation (0-1.5 % w/v) were tested. Because acid whey can be economical fermentation medium, the results of this study could be used for the development of the large-scale production of human lysozyme by using acid whey from fermented dairy products

    Cone beam computed tomographic analysis of maxillary premolars and m olars to detect the relationship between periapical and marginal bone loss and mucosal thickness of maxillary sinus

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    Background: This study assessed the relationship between mucosal thickness (MT) of the maxillary sinus and periodontal bone loss (PBL) and periapical condition of related teeth. We also aimed to identify the association between root apices and the inferior wall of the maxillary sinus using Cone beam computed tomography (CBCT). Material and Methods: In this study, CBCT images of 205 patients with 410 maxillary sinuses were examined, retrospectively. A total of 582 maxillary molars and 587 premolars were observed. The relationship of each root with maxillary sinus and apical lesions of these roots were classified, PBL was examined and the situations of adjacent teeth were estimated. The effect of these conditions on sinus mucosal thickness (MT) was evaluated. Results: There was a significant correlation between MT of maxillary sinus and both PBL and age (r = 0.52, p =0.000 and r = 0.111, p = 0.002, respectively). The frequency of MT increased as the severity of apical lesion enlarged. A positive correlation was found between MT and degree of PBL and periapical lesions. To reveal the association between MT and pulpoperiapical condition bivariate correlation was done and a significant relationship between the pulpoperiapical condition and MT was found (r = 0.17, p =0.000). Conclusions: This retrospective study showed that MT of the maxillary sinus was common among patients with PBL and MT was significantly associated with PBL and apical lesions. The relationship of maxillary sinus to adjacent teeth had also positive correlation with MT. CBCT imaging enabled better evaluation of maxillary sinus, posterior teeth and surrounding structures compared to other imaging tool

    Volume XLVII, Number 27, January 10, 1930

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    Amaç: Yaygın Gelişimsel Bozukluklar (YGB) ve eşlik eden Dikkat Eksikliği Hiperaktivite Bozukluğu (DEHB) belirtileri olan olgularda Metilfenidat (MPH) ilk tedavi seçeneği olmakla birlikte, sadece DEHB olan olgulara göre daha fazla yan etkiye yol açabildiği ve klinik yanıtın çok değişken olabileceği bilinmektedir. Bu çalışmanın amacı YGB ve Hafif Düzey Mental Retardasyonu (MR) olan olguların MPH'a yanıtı- nın yalnızca DEHB olan olgularla karşılaştırılması ve CES-1 gen polimorfizmleriyle ilişkisinin bulunup bulunmadığının belirlenmesidir. Yöntem: YGB ve eşlik eden DEHB varlığında tükürük örneği alınarak MPH'ı metabolize eden enzim olan Karboksilesteraz-1 (CES-1) polimorfizmleri (Arg199/His, Ser75/Asn ve Ile49/Val) incelenmiş olup MPH yanıtı Dikkat Eksikliği ve Yıkıcı Davranış Bozuklukları için DSM-IV'e Dayalı Tarama ve Değerlendirme Ölçeği ve Klinik Global İzlem Ölçeği ile değerlendirilmiştir. Bulgular: YGB ve eşlik eden DEHB varlığında olguların, DEHB, DEHB ve eşlik eden Hafif Düzey Zeka Geriliği olan olgulara göre daha kötü MPH yanıtı verdikleri ve CES-1'de Arg199/His polimorfizminin istatistiksel olarak anlamlı oranda yüksek olduğu bulunmuştur. Sonuç: Bu çalışma YGB ve eşlik eden DEHB olan olgularda CES-1 Arg199/His polimorfizminin incelendiği ilk çalışmadır.Objective: Methylphenidate is the first-choice medication for the Pervasive Developmental Disorders (PDDs), and comorbid Attention Deficit Hyperactivity Disorder (ADHD). But this approach generally results with poor outcomes, and increased adverse effects. It is aimed to investigate the comparison of cases who diagnosed with PDDs and Mild Mental Retardation (MR) and cases with pure ADHD in terms of the clinical response to MPH. Also we aimed to investigate the relations between CES-1 polymorphism gene and the clinical response to MPH.Methods: For clarifying this we searched for three polymorphisms (Arg199/His, Ser75/Asn, and Ile49/Val) in carboxylesterase-1 gene (CES-1) in the saliva of patients diagnosed with PDD+ADHD. Also, we assessed the clinical response to MPH by dimensional approach using the Attention Deficit Hyperactivity Disorder Rating Scale IV and Clinical Global Impression-Improvement scale. Results: PDD+ADHD groups had significantly higher Arg199/His polymorphism, and clinically responded poorer with symptoms sometimes even worsening to the MPH treatment compared with "pure" ADHD and ADHD+MR groups. Conclusion: This is the first study that an association between Arg199/His polymorphism in CES1 and altered treatment response to MPH in patients with PDD that presents with symptoms of ADHD

    Circulation levels of acute phase proteins pentraxin 3 and serum amyloid A in atherosclerosis have correlations with periodontal inflamed surface area

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    Objectives: One of the plausible mechanisms in the relationship between periodontitis and coronary artery disease (CAD) is the systemic inflammatory burden comprised of circulating cytokines/mediators related to periodontitis. This study aims to test the hypothesis that periodontal inflamed surface area (PISA) is correlated with higher circulating levels of acute phase reactants (APR) and pro-inflammatory cytokines/mediators and lower anti-inflammatory cytokines/mediators in CAD patients. Material and Methods: Patients aged from 30 to 75 years who underwent coronary angiography with CAD suspicion were included. Clinical periodontal parameters (probing depth - PD, clinical attachment loss, and bleeding on probing - BOP) were previously recorded and participants were divided into four groups after coronary angiography: Group 1: CAD (+) with periodontitis (n=20); Group 2: CAD (+) without periodontitis (n=20); Group 3: CAD (-) with periodontitis (n=21); Group 4: CAD (-) without periodontitis (n = 16). Serum interleukin (IL) −1, −6, −10, tumor necrosis factor (TNF)-α, serum amyloid A (SAA), pentraxin (PTX) 3, and high-sensitivity C-reactive protein (hs-CRP) levels were measured with ELISA. Results: Groups 1 and 3 showed periodontal parameter values higher than Groups 2 and 4 (p<0.0125). None of the investigated serum parameters were statistically significantly different between the study groups (p>0.0125). In CAD (-) groups (Groups 3 and 4), PISA has shown positive correlations with PTX3 and SAA (p<0.05). Age was found to predict CAD significantly according to the results of the multivariate regression analysis (Odds Ratio: 1.17; 95% Confidence Interval: 1.08-1.27; p<0.001). Conclusions: Although age was found to predict CAD significantly, the positive correlations between PISA and APR in CAD (-) groups deserve further attention, which might depend on the higher PISA values of periodontitis patients. In further studies conducted in a larger population, the stratification of age groups would provide us more accurate results

    Goat hair as a bioindicator of environmental contaminants and adrenal activation during vertical transhumance

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    Autochthonous breeds of livestock are considered a pivotal genetic resource for agriculture, rural development, and food and nutrition security. In the Italian Alps, local livestock breeds are maintained using the traditional alpine farming system based on vertical transhumance, with the use of alpine pastures from late spring to autumn and indoor housing with a hay-based diet for the remaining part of the year. Because of their tight link with the territory of origin, local breeds could be used to biomonitor environmental contaminations. Moreover, animal welfare should also be monitored during transhumance in animals, which are exposed to a sudden farming system change and different types of stressors. For these reasons, this investigation hypothesized that the content of trace elements, heavy metals, and cortisol in the hair of goats changes during vertical transhumance, possibly reflecting different dietary contents and activity of the hypothalamic-pituitary-adrenal (HPA) axis. This study aimed to assess the response of an Italian local goat breed to the change from indoor housing to alpine pasture in summer in terms of hair concentrations of (i) trace elements and heavy metals and (ii) cortisol. The regrown hair of Frisa goats was monthly collected for 2 consecutive years (n = 10 for heavy metals and trace elements and n = 6 for cortisol in 2021, n = 17 for both analyses in 2022), once before vertical transhumance and twice after that event. Hair was then analyzed for trace elements, heavy metals, and cortisol by inductively coupled plasma-optical emission spectrophotometer (ICP-OES) and enzyme immunoassay (EIA), respectively. Data were analyzed by multilevel models. The results showed an increase in As content during alpine pasture (p < 0.01), probably reflecting the soil and water As contents of the grazing area, while Mg, Zn, and Al (p < 0.01) followed the opposite trend, decreasing in the second month after vertical transhumance. Hair cortisol concentrations increased during 2 months of alpine pasture (p < 0.001), indicating an increase in the activation of the HPA axis, in agreement with previous studies. Future investigations can consider a longer study period and the development of ad hoc animal welfare indicators

    DRD4 genotyping may differentiate symptoms of attention-deficit/hyperactivity disorder and sluggish cognitive tempo

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    Objective: Studies to reduce the heterogeneity of attention-deficit/hyperactivity disorder (ADHD) have increased interest in the concept of sluggish cognitive tempo (SCT). The aim of this study was to investigate if the prevalence of two variable-number tandem repeats (VNTRs) located within the 30 -untranslated region of the DAT1 gene and in exon 3 of the dopamine D4 receptor (DRD4) gene differ among four groups (31 subjects with SCT but no ADHD, 146 individuals with ADHD but no SCT, 67 subjects with SCT + ADHD, and 92 healthy controls). Methods: We compared the sociodemographic profiles, neurocognitive domains, and prevalence of two VNTRs in SCT and ADHD subjects versus typically developing (TD) controls. Results: The SCT without ADHD group had a higher proportion of females and lower parental educational attainment. Subjects in this group performed worse on neuropsychological tests, except for psychomotor speed and commission errors, compared to controls. However, the ADHD without SCT group performed significantly worse on all neuropsychological domains than controls. We found that 4R homozygosity for the DRD4 gene was most prevalent in the ADHD without SCT group. The SCT without ADHD group had the highest 7R allele frequency, differing significantly from the ADHD without SCT group. Conclusion: The 7R allele of DRD4 gene was found to be significantly more prevalent in SCT cases than in ADHD cases. No substantial neuropsychological differences were found between SCT and ADHD subjects

    Diagnostic approach of tuberculous lymphadenitis in a multicenter study

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    Introduction: Tuberculous lymphadenitis (TBLN) is the most common infectious etiology of peripheral lymphadenopathy in adults, in Turkiye. This study aimed to identify the demographic, clinical, and laboratory variables that differentiate TBLN from non-tuberculous lymphadenitis (NTBLN), as well as the etiology of lymphadenopathy in adults. Methodology: Patients who were over 18 years old and were referred to the infectious disease outpatient clinics with complaints of swollen peripheral lymph nodes, and who underwent lymph node biopsy between 1 January 2010 and 1 March 2021, were included in this multicenter, nested case-control study. Results: A total of 812 patients at 17 tertiary teaching and research hospitals in Turkiye were included in the study. TBLN was the most frequent diagnosis (53.69%). The proportion of patients diagnosed with TBLN was higher among females; and among those who had a higher erythrocyte sedimentation rate, positive purified protein derivative test, and positive interferon-gamma release test result (p < 0.05). However, TBLN was less frequent among patients with generalized lymphadenopathy, bilateral lymphadenopathy, axillary lymphadenopathy, inguinal lymphadenopathy, hepatomegaly, splenomegaly, leukocytosis, and moderately increased C reactive protein levels (p < 0.05). Conclusions: Identifying the variables that predict TBLN or discriminate TBLN from NTBLN will help clinicians establish optimal clinical strategies for the diagnosis of adult lymphadenopathy

    Quality characteristics of traditional sepet cheese

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    Thesis (Master)--Izmir Institute of Technology, Food Engineering, Izmir, 2009Includes bibliographical references (leaves: 103-109)Text in English; Abstract: Turkish and Englishxiii, 112 leavesInvestigation and registration of traditional foods contributes to the improvement of economy and the continuation of important elements of a nation.s culinary heritage, culture. Various types of traditional cheese are present in different shape, color, taste in the world. Sepet cheese is one of the traditional cheeses produced in the Aegean region. In this study, chemical, physical, microbiological, organoleptic, and aroma characteristics of traditional sepet cheeses were investigated. The changes in the quality characteristics were examined during production and ripening periods. The natural lactic acid bacteria flora of sepet cheeses during production and ripening was identified with phenotyphic methods. As a result of chemical analysis, average chemical characteristics of traditional sepet cheeses were found as 54.33 %±5.17 total solid content, 0.82±0.05 water activity, 25.11 %±2.86 fat content, 5.58±0.43 pH, 28.99 %±2.12 protein content. According to microbiological analysis of sepet cheeses, average total aerobic, lactococci, lactobacilli, enterococci, psychrotrophic bacteria, Staphylococcus aureus, yeast, mold, coliform bacteria counts were 7.64±1.18, 7.38±1.10, 7.38±0.99, 6.99±0.99, 5.37±1.15, 1.25±1.72, 3.22±0.25, 0.95±0.96, 2.72±1.82 log cfu/g, respectively. During descriptive profile analysis, traditional sepet cheeses were described with free fatty acid, cooked, creamy, whey, animal like, sulfurous aromatic descriptives with high salty basic taste. Free fatty acids were found to be the most abundant volatile compounds of sepet cheeses and had the highest aroma intensities in volatile fraction. According to phenotypic identification, isolates were closely related to Lactococcus lactis subsp. lactis, Lactobacillus casei spp. rhamnosus, L. plantarum, heterofermentative Lactobacillus spp., Streptococcus thermophilus, Leuconostoc spp., Enterococcus durans and E. faceium
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