1,304 research outputs found
Road freight logistics, competition, and innovation : downstream benefits and policy implications
This empirical paper sheds light on a significant element of the debate of whether infrastructure services have a strong impact on economic development by exploring the impact of innovative road freight services on downstream business users. The paper uses a new and purpose-specific survey of 165 logistics service providers and 493 user enterprises in food processing, food distribution, and the automotive industry in the Czech Republic, Hungary, and Poland. The main findings are that there are substantial downstream benefits from innovations in road freight services, both dampening cost increases and raising sales revenues of business users. The additional finding that increased intensity of competition in road freight services is significantly associated with the provision of innovative services suggests that easing any remaining barriers to competition in upstream business sectors should be a priority.Municipal Financial Management,ICT Policy and Strategies,Private Participation in Infrastructure,Business in Development,Business Environment
Constraints on the time-scale of nuclear breakup from thermal hard-photon emission
Measured hard photon multiplicities from second-chance nucleon-nucleon
collisions are used in combination with a kinetic thermal model, to estimate
the break-up times of excited nuclear systems produced in nucleus-nucleus
reactions at intermediate energies. The obtained nuclear break-up time for the
{Xe} + {Sn} reaction at 50{\it A} MeV is
100 -- 300 fm/ for all reaction centralities. The lifetime of the
radiating sources produced in seven other different heavy-ion reactions studied
by the TAPS experiment are consistent with 100 fm/,
such relatively long thermal photon emission times do not support the
interpretation of nuclear breakup as due to a fast spinodal process for the
heavy nuclear systems studied.Comment: 11 pages, 9 figures, submitted to EPJ
Does more intense competition lead to higher growth?
The relationship between the intensity of competition in an economy and its long-run growth is an open question in economics. Theoretically, there is no clear-cut answer. Empirical evidence exists, however, that in some sectors more competition leads to more innovation, and accelerates productivity growth. To complement those findings, and capture economy-wide effects, the authors conduct a cross-country study. They examine the impact on growth of various measures having to do with intensity of domestic competition - beyond the effects of trade liberalization. Their results indicate a strong correlation between long-run growth, and effective enforcement of antitrust, and competition policy.Environmental Economics&Policies,Economic Theory&Research,ICT Policy and Strategies,Labor Policies,Decentralization,Economic Theory&Research,Environmental Economics&Policies,ICT Policy and Strategies,Achieving Shared Growth,Governance Indicators
Green growth, technology and innovation
The paper explores existing patterns of green innovation and presents an overview of green innovation policies for developing countries. The key findings from the empirical analysis are: (1) frontier green innovations are concentrated in high-income countries, few in developing countries but growing; (2) the most technologically-sophisticated developing countries are emerging as significant innovators but limited to a few technology fields; (3) there is very little South-South collaboration; (4) there is potential for expanding green production and trade; and (5) there has been little base-of-pyramid green innovation to meet the needs of poor consumers, and it is too early to draw conclusions about its scalability. To promote green innovation, technology and environmental policies work best in tandem, focusing on three complementary areas: (1) to promote frontier innovation, it is advisable to limit local technology-push support to countries with sufficient technological capabilities -- but there is also a need to provide global technology-push support for base-of-pyramid and neglected technologies including through a pool of long-term, stable funds supported by demand-pull mechanisms such as prizes; (2) to promote catch-up innovation, it is essential both to facilitate technology access and to stimulate technology absorption by firms -- with critical roles played by international trade and foreign direct investment, with firm demand spurred by public procurement, regulations and standards; and (3) to develop absorptive capacity, there is a need to strengthen skills and to improve the prevailing business environment for innovation -- to foster increased experimentation, global learning, and talent attraction and retention. There is still considerable progress to be made in ranking green innovation policies as most appropriate for different developing country contexts -- based on more impact evaluation studies of innovation policies targeted at green technologies.Environmental Economics&Policies,E-Business,ICT Policy and Strategies,Technology Industry,Climate Change Mitigation and Green House Gases
Technological Learning and Innovation: Climbing a Tall Ladder
As the global stock of ideas expands and diffuses across and within countries, technological learning is poised to become an even more important determinant of growth through its impact on innovation. This note reviews global trends that make a policy focus on technological learning and innovation more important than ever for developing countries. The note explores how the recent global financial crisis may affect these trends and outlines several implications of these trends for innovation policy moving forward. Developing countries would benefit from an increased policy emphasis on technological learning and the adoption of more efficient existing technologies to generate more and better jobs and higher standards of living.technology, learning, skills, training, innovation, knowledge transfer, growth, developing countires, financial crisis, jobs
Regulatory reform, competition, and innovation - a case study of the Mexican road freight industry
Discussions of competition and regulatory reform typically focus on price and quantity effects. But improving certain infrastructure services can also stimulate entry, and competition in user industries downstream, allowing new firms to enter, incumbent users to offer new products, and rivalry to intensify. The authors present a case study of how innovations in road freight services affect selected downstream users of those services after regulatory reform. After a period of rigid regulation, and heavy government interference, Mexico in 1989 developed a new policy framework for road transport, with free entry, and market-based price setting. The result: faster, more reliable trucking has allowed user companies to offer new, previously unavailable products, and to reach new areas with existing products. Cheaper, more customer-responsive trucking services have allowed logistical innovations in user firms, and some user firms have decided not to keep their own fleets of trucks, but to outsource trucking services on the open market, thereby converting fixed costs to variable costs. For one fertilizer company, the benefits of reform included a ten percent improvement in operating margin. Successful reform requires careful planning and execution, and political support at high levels. Regulatory reform also profoundly changes the sectoral institution formerly responsible for the regulation. Enough resources should be provided to help organizations in the reformed industry make the transition to the post-reform environment - helping with such tasks as defining the organization's new role, and facilitating the redeployment of staff. The national competition agency can help greatly in laying the groundwork for reform by making a compelling case for the reform's expected benefits. After reform, the competition agency should also help with enforcement, to ensure that the cozy, cartel-like behavior stimulated by tight entry restrictions does not persist. In Mexico, three strong interventions were required to discipline attempted anti-competitive practices in the trucking industry in the years following reform.Common Carriers Industry,Environmental Economics&Policies,Roads&Highways,Transport and Trade Logistics,Banks&Banking Reform,Roads&Highways,Transport and Trade Logistics,Common Carriers Industry,ICT Policy and Strategies,Environmental Economics&Policies
Towards patient selection for cranial proton beam therapy – Assessment of current patient-individual treatment decision strategies
Proton beam therapy shows dosimetric advantages in terms of sparing healthy tissue compared to conventional photon radiotherapy. Those patients who are supposed to experience the greatest reduction in side effects should preferably be treated with proton beam therapy. One option for this patient selection is the model-based approach. Its feasibility in patients with intracranial tumours is investigated in this thesis. First, normal tissue complication probability models for early and late side effects were developed and validated in external cohorts based on data of patients treated with proton beam therapy. Acute erythema as well as acute and late alopecia were associated with high-dose parameters of the skin. Late mild hearing loss was related to the mean dose of the ipsilateral cochlea. Second, neurocognitive function as a relevant side effect for brain tumour patients was investigated in detail using subjective and objective measures. It remained largely stable during recurrence-free follow-up until two years after proton beam therapy. Finally, potential toxicity differences were evaluated based on an individual proton and photon treatment plan comparison as well as on models predicting various side effects. Although proton beam therapy was able to achieve a high relative reduction of dose exposure in contralateral organs at risk, the associated reduction of side effect probabilities was less pronounced. Using a model-based selection procedure, the majority of the examined patients would have been eligible for proton beam therapy, mainly due to the predictions of a model on neurocognitive function.:1. Introduction
2. Theoretical background
2.1 Treatment strategies for tumours in the brain and skull base
2.1.1 Gliomas
2.1.2 Meningiomas
2.1.3 Pituitary adenomas
2.1.4 Tumours of the skull base
2.1.5 Role of proton beam therapy
2.2 Radiotherapy with photons and protons
2.2.1 Biological effect of radiation
2.2.2 Basic physical principles of radiotherapy
2.2.3 Field formation in radiotherapy
2.2.4 Target definition and delineation of organs at risk
2.2.5 Treatment plan assessment
2.3 Patient outcome
2.3.1 Scoring of side effects
2.3.2 Patient-reported outcome measures – Quality of life
2.3.3 Measures of neurocognitive function
2.4 Normal tissue complication probability models
2.4.1 Types of NTCP models
2.4.2 Endpoint definition and parameter fitting
2.4.3 Assessment of model performance
2.4.4 Model validation
2.5 Model-based approach for patient selection for proton beam therapy
2.5.1 Limits of randomised controlled trials
2.5.2 Principles of the model-based approach
3. Investigated patient cohorts
4. Modelling of side effects following cranial proton beam therapy
4.1 Experimental design for modelling early and late side effects
4.2 Modelling of early side effects
4.2.1 Results
4.2.2 Discussion
4.3 Modelling of late side effects
4.3.1 Results
4.3.2 Discussion
4.4 Interobserver variability of alopecia and erythema assessment
4.4.1 Patient cohort and experimental design
4.4.2 Results
4.4.3 Discussion
4.5 Summary
5. Assessing the neurocognitive function following cranial proton beam therapy
5.1 Patient cohort and experimental design
5.2 Results
5.2.1 Performance at baseline
5.2.2 Correlation between subjective and objective measures
5.2.3 Time-dependent score analyses
5.3 Discussion and conclusion
5.4 Summary
6. Treatment plan and NTCP comparison for patients with intracranial tumours
6.1 Motivation
6.2 Treatment plan comparison of cranial proton and photon radiotherapy
6.2.1 Patient cohort and experimental design
6.2.2 Results
6.2.3 Discussion
6.3 Application of NTCP models
6.3.1 Patient cohort and experimental design
6.3.2 Results
6.3.3 Discussion
6.4 Summary
7. Conclusion and further perspectives
8. Zusammenfassung
9. Summar
Competition and innovation-driven inclusive growth
The paper investigates the strength of innovation-driven employment growth, the role of competition in stimulating and facilitating it, and whether it is inclusive. In a sample of more than 26,000 manufacturing establishments across 71 countries (both OECD and developing), the authors find that firms that innovate in products or processes, or that have attained higher total factor productivity, exhibit higher employment growth than non-innovative firms. The strength of firms'innovation-driven employment growth is significantly positively associated with the share of the firms'workforce that is unskilled, debunking the conventional wisdom that innovation-driven growth is not inclusive in that it is focused on jobs characterized by higher levels of qualification. They also find that young firms have higher propensities for product or process innovation in countries with better Doing Business ranks (both overall and ranks for constituent components focused on credit availability and property registration). Firms generally innovate more and show greater employment growth if they are exposed to more information (through internet use and membership in business organizations) and are exporters. The empirical results support the policy propositions that innovation is a powerful driver of employment growth, that innovation-driven growth is inclusive in its creation of unskilled jobs, and that the underlying innovations are fostered by a pro-competitive business environment providing ready access to information, financing, export opportunities, and other essential business services that facilitate the entry and expansion of young firms.Environmental Economics&Policies,Labor Policies,Labor Markets,E-Business,Microfinance
The Role of Interactions in Systems of Single Domain Ferrimagnetic Iron Oxide Nanoparticles
Magnetic nanoparticles are interesting materials for a lot of medical and technical applications. A less experimentally investigated question is the influence of particle packing density on magnetic properties due to magnetic interactions between single particles. For this, magnetic nanoparticles of iron oxides prepared as fine dry powder by laser deposition are investigated with respect to their structural and magnetic properties as function of packing density. The particles are nearly spherically shaped single crystals in the magnetic single domain size range with a mean diameter of 21 nm occasionally exhibiting spinel growth facets. Powders of these particles are diluted by nonmagnetic silicon oxide particles in a range of volume concentrations from 0.2 % up to 68 % of the bulk density of magnetite. The concentration dependence of remanence, coercivity and hysteresis losses is determined by measurements of minor loops in a vibrating sample magnetometer. Results which are discussed in the frame of present theoretical models may be understood in terms of the cubic anisotropy of magnetite distorted by a small uniaxial shape contribution.
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