1,333 research outputs found

    Fast and Slow Processes Underlying Theories of Information Technology Use

    Get PDF
    Although theories of information technology (IT) use have been widely researched, organizations continue to struggle with insufficiently utilizing their IT assets. Those interested in understanding and managing IT use need both novel theoretical development and new directions for future research. In this paper, we address both of these needs. Regarding the first need, we develop novel theory by explaining two types of cognitive processes—one fast and one slow—that underlie theories of IT use. The impetus for our explanation of underlying processes (EUP) comes from studies of IT use that have found moderating effects of previous interaction with IT. With these results, researchers have concluded that cognitions are less important in determining IT use as the use of that IT increases. Consistent with that conclusion, our EUP posits that, as learning from prior use occurs, the influence of fast, automatic, unconscious (type 1) cognitive processes increases while the influence decreases for slow, controlled, conscious (type 2) cognitive processes. Type 1 processes automatically generate a default type 1 response; type 2 processes have the potential to generate an intervening type 2 response. The intervention potential is highest for initial use of the target IT and lowest when learning is high such that use of the IT has become automatic. From our EUP, we develop three insights: 1) that the cognitions that lead to a default response are not necessarily the cognitions found in extant theories of IT use, 2) that both type 1 and type 2 processes are subject to bounded rationality, and 3) that the relationship between learning and the intervention potential for a type 2 response, although negative, may not be linear. To address the second need that we note above, we suggest new directions for future research, which includes investigating the cognitive control problem (i.e., when type 2 processes intervene) and exploring the effects of heuristics, nudges, and bounded rationality on decisions to use IT. Beyond the hope that the suggested directions for research will yield solutions for addressing the underutilization of IT assets, the fundamental advances in theoretical understanding that we present here suggest notable implications for practice, including developing brief, simple, cognitively unconscious messages directed at nudging decision makers toward a default response to use the target IT

    Machine-Stitched E-Textile Stretch Sensors

    Get PDF
    Wearable, garment-integrated sensing is a distinct challenge for many reasons. Significant among these reasons is the challenge of fabricating sensors that are unobtrusive and comfortable for longterm daily wear. Here, we present a novel method for fabricating e-textile stretch sensors using industrial sewing machinery. The resulting sensors are perceptually similar to existing stitches used in garment fabrication, offering improvements in comfort and ease of manufacture compared to other types of sensors

    A pilot sequential multiple assignment randomized trial (SMART) protocol for developing an adaptive coaching intervention around a mobile application for athletes to improve carbohydrate periodization behavior

    Get PDF
    Background: It has recently been identified that manipulating carbohydrate availability around exercise activity can enhance training-induced metabolic adaptations. Despite this approach being accepted in the athletic populations, athletes do not systematically follow the guidelines. Digital environments appear to allow nutritionists to deliver this intervention at scale, reducing expensive human coaching time. Yet, digitally delivered dietary behavior change interventions for athletes and the coaching strategy to support them are still novel concepts within sports nutrition. Methods/design: We aim to recruit 900 athletes across the UK. 500 athletes will be recruited to test the feasibility of a novel menu planner mobile application with coaching for 6 weeks. 250 athletes with pre-existing nutritionist support will also be recruited as control. We will then conduct a 4-week pilot sequential multiple assignment randomized trial (SMART) with an additional 150 athletes. In the SMART, athletes will be given the application and additional coaching according to their engagement responses. The primary outcomes are the mobile application and coach uptake, retention, engagement, and success in attaining carbohydrate periodization behavior. Secondary outcomes are changes in goal, weight, carbohydrate periodization self-efficacy, and beliefs about consequences. Due to the high attrition nature of digital interventions, all quantitative analyses will be carried out based on both the intention-to-treat and per-protocol principles. Discussion: This study will be the first to investigate improving carbohydrate periodization using a digital approach and tailored coaching strategies under this context. Foundational evidence from this study will provide insights into the feasibility of the digital approach

    Determining the serotype composition of mixed samples of pneumococcus using whole-genome sequencing.

    Get PDF
    Serotyping of Streptococcus pneumoniae is a critical tool in the surveillance of the pathogen and in the development and evaluation of vaccines. Whole-genome DNA sequencing and analysis is becoming increasingly common and is an effective method for pneumococcal serotype identification of pure isolates. However, because of the complexities of the pneumococcal capsular loci, current analysis software requires samples to be pure (or nearly pure) and only contain a single pneumococcal serotype. We introduce a new software tool called SeroCall, which can identify and quantitate the serotypes present in samples, even when several serotypes are present. The sample preparation, library preparation and sequencing follow standard laboratory protocols. The software runs as fast as or faster than existing identification tools on typical computing servers and is freely available under an open source licence at https://github.com/knightjimr/serocall. Using samples with known concentrations of different serotypes as well as blinded samples, we were able to accurately quantify the abundance of different serotypes of pneumococcus in mixed cultures, with 100?% accuracy for detecting the major serotype and up to 86?% accuracy for detecting minor serotypes. We were also able to track changes in serotype frequency over time in an experimental setting. This approach could be applied in both epidemiological field studies of pneumococcal colonization and experimental laboratory studies, and could provide a cheaper and more efficient method for serotyping than alternative approaches

    A surprising consistency between the far-infrared galaxy luminosity functions of the field and Coma

    Get PDF
    We present new deep images of the Coma Cluster from the ESA Herschel Space Observatory at wavelengths of 70, 100 and 160 mu m, covering an area of 1.75 x 1.0 square degrees encompassing the core and south-west infall region. Our data display an excess of sources at flux densities above 100 mJy compared to blank-field surveys, as expected. We use extensive optical spectroscopy of this region to identify cluster members and hence produce cluster luminosity functions in all three photometric bands. We compare our results to the local field galaxy luminosity function, and the luminosity functions from the Herschel Virgo Cluster Survey. We find consistency between the shapes of the Coma and field galaxy luminosity functions at all three wavelengths; however, we do not find the same level of agreement with that of the Virgo Cluster.</p

    A surprising consistency between the far-infrared galaxy luminosity functions of the field and Coma

    Get PDF
    We present new deep images of the Coma Cluster from the ESA Herschel Space Observatory at wavelengths of 70, 100 and 160 ÎŒm, covering an area of 1.75 × 1.0 square degrees encompassing the core and south-west infall region. Our data display an excess of sources at flux densities above 100 mJy compared to blank-field surveys, as expected. We use extensive optical spectroscopy of this region to identify cluster members and hence produce cluster luminosity functions in all three photometric bands. We compare our results to the local field galaxy luminosity function, and the luminosity functions from the Herschel Virgo Cluster Survey. We find consistency between the shapes of the Coma and field galaxy luminosity functions at all three wavelengths; however, we do not find the same level of agreement with that of the Virgo Cluster

    Molecular profiling of signet ring cell colorectal cancer provides a strong rationale for genomic targeted and immune checkpoint inhibitor therapies

    Get PDF
    We would like to thank all patients whose samples were used in this study. We are also thankful to the Northern Ireland Biobank and Grampian Biorepository for providing us with tissue blocks and patient data; and Dr HG Coleman (Queen’s University Belfast) for her advice on statistical analyses. This work has been carried out with financial support from Cancer Research UK (grant: C11512/A18067), Experimental Cancer Medicine Centre Network (grant: C36697/A15590 from Cancer Research UK and the NI Health and Social Care Research and Development Division), the Sean Crummey Memorial Fund and the Tom Simms Memorial Fund. The Northern Ireland Biobank is funded by HSC Research and Development Division of the Public Health Agency in Northern Ireland and Cancer Research UK through the Belfast CRUK Centre and the Northern Ireland Experimental Cancer Medicine Centre; additional support was received from Friends of the Cancer Centre. The Northern Ireland Molecular Pathology Laboratory which is responsible for creating resources for the Northern Ireland Biobank has received funding from Cancer Research UK, Friends of the Cancer Centre and Sean Crummey Foundation.Peer reviewedPublisher PD

    Climate and lawn management interact to control C4 plant distribution in residential lawns across seven U.S. cities.

    Get PDF
    Author Posting. © Ecological Society of America, 2019. This article is posted here by permission of Ecological Society of America for personal use, not for redistribution. The definitive version was published in Trammell, T. L. E., Pataki, D. E., Still, C. J., Ehleringer, J. R., Avolio, M. L., Bettez, N., Cavender-Bares, J., Groffman, P. M., Grove, M., Hall, S. J., Heffernan, J., Hobbie, S. E., Larson, K. L., Morse, J. L., Neill, C., Nelson, K. C., O'Neil-Dunne, J., Pearse, W. D., Chowdhury, R. R., Steele, M., & Wheeler, M. M. Climate and lawn management interact to control C4 plant distribution in residential lawns across seven U.S. cities. Ecological Applications, 29(4), (2019): e01884, doi: 10.1002/eap.1884.In natural grasslands, C4 plant dominance increases with growing season temperatures and reflects distinct differences in plant growth rates and water use efficiencies of C3 vs. C4 photosynthetic pathways. However, in lawns, management decisions influence interactions between planted turfgrass and weed species, leading to some uncertainty about the degree of human vs. climatic controls on lawn species distributions. We measured herbaceous plant carbon isotope ratios (ÎŽ13C, index of C3/C4 relative abundance) and C4 cover in residential lawns across seven U.S. cities to determine how climate, lawn plant management, or interactions between climate and plant management influenced C4 lawn cover. We also calculated theoretical C4 carbon gain predicted by a plant physiological model as an index of expected C4 cover due to growing season climatic conditions in each city. Contrary to theoretical predictions, plant ÎŽ13C and C4 cover in urban lawns were more strongly related to mean annual temperature than to growing season temperature. Wintertime temperatures influenced the distribution of C4 lawn turf plants, contrary to natural ecosystems where growing season temperatures primarily drive C4 distributions. C4 cover in lawns was greatest in the three warmest cities, due to an interaction between climate and homeowner plant management (e.g., planting C4 turf species) in these cities. The proportion of C4 lawn species was similar to the proportion of C4 species in the regional grass flora. However, the majority of C4 species were nonnative turf grasses, and not of regional origin. While temperature was a strong control on lawn species composition across the United States, cities differed as to whether these patterns were driven by cultivated lawn grasses vs. weedy species. In some cities, biotic interactions with weedy plants appeared to dominate, while in other cities, C4 plants were predominantly imported and cultivated. Elevated CO2 and temperature in cities can influence C3/C4 competitive outcomes; however, this study provides evidence that climate and plant management dynamics influence biogeography and ecology of C3/C4 plants in lawns. Their differing water and nutrient use efficiency may have substantial impacts on carbon, water, energy, and nutrient budgets across cities.This research was funded by a series of collaborative grants from the U.S. National Science Foundation Macrosystems Biology Program (EF‐1065548, 1065737, 1065740, 1065741, 1065772, 1065785, 1065831, 121238320). The authors thank La'Shaye Ervin, William Borrowman, Moumita Kundu, and Barbara Uhl for field and laboratory assistance
    • 

    corecore