Carnal encounters and producing socialist Yugoslavia: voluntary youth labour actions on the newsreel screen

This article explores the role that the newsreel genre played in the production of socialist Yugoslav territory, understood as reshaping the body of the socius. We analyse news reports concerning voluntary youth labour actions, which were one of the most important features of Yugoslav socialist society and which featured heavily in Yugoslav official newsreels. We argue that the newsreel provided a specific liminal space in between the ‘real’/non-cinematic and ‘screened’/cinematic experience, where we locate occurrences of carnal encounters between the body on the cinematic screen and the body of the audience. In this regard, we discuss two characteristic types of frame which were present in the newsreel reports on labour actions: the somatic frame and the machinic-labour frame

Respiratory dysfunction three months after severe COVID-19 is associated with gut microbiota alterations

Background: Although coronavirus disease 2019 (COVID-19) is primarily a respiratory infection, mounting evidence suggests that the gastrointestinal (GI) tract is involved in the disease, with gut barrier dysfunction and gut microbiota alterations being related to disease severity. Whether these alterations persist and are related to long-term respiratory dysfunction remains unknown. Methods: Plasma was collected during hospital admission and after three months from the NOR-Solidarity trial (n = 181) and analysed for markers of gut barrier dysfunction and inflammation. At the three-month follow-up, pulmonary function was assessed by measuring the diffusing capacity of the lungs for carbon monoxide (DLCO ). Rectal swabs for gut microbiota analyses were collected (n = 97) and analysed by sequencing the 16S rRNA gene. Results: Gut microbiota diversity was reduced in COVID-19 patients with respiratory dysfunction, defined as DLCO below the lower limit of normal three months after hospitalisation. These patients also had an altered global gut microbiota composition, with reduced relative abundance of 20 bacterial taxa and increased abundance of five taxa, including Veillonella, potentially linked to fibrosis. During hospitalisation, increased plasma levels of lipopolysaccharide-binding protein (LBP) were strongly associated with respiratory failure, defined as pO2 /fiO2 -(P/F ratio)Respiratory dysfunction three months after severe COVID-19 is associated with gut microbiota alterationsacceptedVersio

Thrombocytopenia and platelet transfusions in ICU patients: an international inception cohort study (PLOT-ICU)

Purpose Thrombocytopenia (platelet count < 150 × 109/L) is common in intensive care unit (ICU) patients and is likely associated with worse outcomes. In this study we present international contemporary data on thrombocytopenia in ICU patients. Methods We conducted a prospective cohort study in adult ICU patients in 52 ICUs across 10 countries. We assessed frequencies of thrombocytopenia, use of platelet transfusions and clinical outcomes including mortality. We evaluated pre-selected potential risk factors for the development of thrombocytopenia during ICU stay and associations between thrombocytopenia at ICU admission and 90-day mortality using pre-specified logistic regression analyses. Results We analysed 1166 ICU patients; the median age was 63 years and 39.5% were female. Overall, 43.2% (95% confidence interval (CI) 40.4–46.1) had thrombocytopenia; 23.4% (20–26) had thrombocytopenia at ICU admission, and 19.8% (17.6–22.2) developed thrombocytopenia during their ICU stay. Non-AIDS-, non-cancer-related immune deficiency, liver failure, male sex, septic shock, and bleeding at ICU admission were associated with the development of thrombocytopenia during ICU stay. Among patients with thrombocytopenia, 22.6% received platelet transfusion(s), and 64.3% of in-ICU transfusions were prophylactic. Patients with thrombocytopenia had higher occurrences of bleeding and death, fewer days alive without the use of life-support, and fewer days alive and out of hospital. Thrombocytopenia at ICU admission was associated with 90-day mortality (adjusted odds ratio 1.7; 95% CI 1.19–2.42). Conclusion Thrombocytopenia occurred in 43% of critically ill patients and was associated with worse outcomes including increased mortality. Platelet transfusions were given to 23% of patients with thrombocytopenia and most were prophylactic.publishedVersio

Thrombocytopenia and platelet transfusions in ICU patients: an international inception cohort study (PLOT-ICU)

Purpose: Thrombocytopenia (platelet count &lt; 150 × 109/L) is common in intensive care unit (ICU) patients and is likely associated with worse outcomes. In this study we present international contemporary data on thrombocytopenia in ICU patients. Methods: We conducted a prospective cohort study in adult ICU patients in 52 ICUs across 10 countries. We assessed frequencies of thrombocytopenia, use of platelet transfusions and clinical outcomes including mortality. We evaluated pre-selected potential risk factors for the development of thrombocytopenia during ICU stay and associations between thrombocytopenia at ICU admission and 90-day mortality using pre-specified logistic regression analyses. Results: We analysed 1166 ICU patients; the median age was 63 years and 39.5% were female. Overall, 43.2% (95% confidence interval (CI) 40.4–46.1) had thrombocytopenia; 23.4% (20–26) had thrombocytopenia at ICU admission, and 19.8% (17.6–22.2) developed thrombocytopenia during their ICU stay. Absence of acquired immune deficiency syndrome (AIDS), non-cancer-related immune deficiency, liver failure, male sex, septic shock, and bleeding at ICU admission were associated with the development of thrombocytopenia during ICU stay. Among patients with thrombocytopenia, 22.6% received platelet transfusion(s), and 64.3% of in-ICU transfusions were prophylactic. Patients with thrombocytopenia had higher occurrences of bleeding and death, fewer days alive without the use of life-support, and fewer days alive and out of hospital. Thrombocytopenia at ICU admission was associated with 90-day mortality (adjusted odds ratio 1.7; 95% CI 1.19–2.42). Conclusion: Thrombocytopenia occurred in 43% of critically ill patients and was associated with worse outcomes including increased mortality. Platelet transfusions were given to 23% of patients with thrombocytopenia and most were prophylactic

Chronic fatigue syndromes: real illnesses that people can recover from

The ‘Oslo Chronic Fatigue Consortium’ consists of researchers and clinicians who question the current narrative that chronic fatigue syndromes, including post-covid conditions, are incurable diseases. Instead, we propose an alternative view, based on research, which offers more hope to patients. Whilst we regard the symptoms of these conditions as real, we propose that they are more likely to reflect the brain's response to a range of biological, psychological, and social factors, rather than a specific disease process. Possible causes include persistent activation of the neurobiological stress response, accompanied by associated changes in immunological, hormonal, cognitive and behavioural domains. We further propose that the symptoms are more likely to persist if they are perceived as threatening, and all activities that are perceived to worsen them are avoided. We also question the idea that the best way to cope with the illness is by prolonged rest, social isolation, and sensory deprivation. Instead, we propose that recovery is often possible if patients are helped to adopt a less threatening understanding of their symptoms and are supported in a gradual return to normal activities. Finally, we call for a much more open and constructive dialogue about these conditions. This dialogue should include a wider range of views, including those of patients who have recovered from them

Intimacy in contemporary digital cinema

Critical discourses on contemporary digital cinema tend to be either overtly negative, framed within a rhetoric of loss or disenfranchisement, or unilaterally positive, celebrating the user agency and freedom digital technologies enable. Both these conceptual positions are unhelpful because they either focus on what contemporary digital cinema fails to do or what it should do, without examining more closely how it actually functions. What is needed is a third, neutral approach which takes both sides into consideration but is also aware of their limitations and weaknesses. This thesis takes as its impetus Giles Deleuze’s suggestion that, just like the cinemas of the movement-image and the time-image before it, contemporary digital cinema needs a basic will to art – a new aesthetic principle, a new function of the image, a new politics, a new representational potential distinct from those that have come before it. The aim of this thesis is therefore to establish this will to art and explore its ramifications for and manifestations in contemporary digital cinema. Taking into consideration a variety of filmic texts from the 1980s to the present day which prominently feature diegetically recorded footage, as well as amateur film-making practices from the home movies of the 1960s to the video clips now uploaded to online media sharing platforms, the increasing relevance of home media in the reception of contemporary digital cinema, and most crucially the process of convergence inherent in digital media, this thesis argues that the will to art of contemporary digital cinema is intimacy.EThOS - Electronic Theses Online ServiceGBUnited Kingdo

External validation of SAPS II score reported to the Norwegian Intensive Care and Pandemic Registry (NIPaR)

Background: Simplified Acute Physiology Score II (SAPS II) is a mortality prediction model widely used to compensate for differences between intensive care units (ICU) in benchmarking and research. Accuracy of SAPS II is sparsely documented. We investigate accuracy by comparing patient journal SAPS II values with registry SAPS II values in the Norwegian Intensive Care and Pandemic Registry (NIPaR). Method: NIPaR personnel collected data from the patient journal during visitations to ICUs in ten different hospitals between 2017 and 2022 while blinded for registry SAPS II data. The patient journal SAPS II values were subsequently compared with the registry SAPS II values. Results: Difference of means for SAPS II score between patient journal and registry data was 5.2 points (95% CI 2.8–7.6; p < 0.001). SAPS II score depended significantly on ICU (p < 0.001) and data origin (p = 0.006), whereas the interaction term for these two variables was not significant. Conclusion: We find low accuracy of SAPS II score in a registry setting.publishedVersio