157 research outputs found
Swirling around filaments: are large-scale structure vortices spinning up dark halos?
The kinematic analysis of dark matter and hydrodynamical simulations suggests
that the vorticity in large-scale structure is mostly confined to, and
predominantly aligned with their filaments, with an excess of probability of 20
per cent to have the angle between vorticity and filaments direction lower than
60 degrees relative to random orientations. The cross sections of these
filaments are typically partitioned into four quadrants with opposite vorticity
sign, arising from multiple flows, originating from neighbouring walls. The
spins of halos embedded within these filaments are consistently aligned with
this vorticity for any halo mass, with a stronger alignment for the most
massive structures up to an excess of probability of 165 per cent. On large
scales, adiabatic/cooling hydrodynamical simulations display the same vorticity
in the gas as in the dark matter. The global geometry of the flow within the
cosmic web is therefore qualitatively consistent with a spin acquisition for
smaller halos induced by this large-scale coherence, as argued in Codis et al.
(2012). In effect, secondary anisotropic infall (originating from the
vortex-rich filament within which these lower-mass halos form) dominates the
angular momentum budget of these halos. The transition mass from alignment to
orthogonality is related to the size of a given multi-flow region with a given
polarity. This transition may be reconciled with the standard tidal torque
theory if the latter is augmented so as to account for the larger scale
anisotropic environment of walls and filaments.Comment: 17 pages, 19 figures, 3 tables. accepted for publication in MNRA
Changes in training load, running performance, lower body power and biochemical characteristics of back players throughout a professional Rugby Union season
The aim of this study was to observe and quantify changes in training load (TL), running performance, lower body power and biochemical characteristics of professional rugby union back players over an entire season. Eight professional players (age: 25.8 ± 4.6 y) participated in this study. Session-RPE (S-RPE) and microtechnologies (GPS) were used for assessing training load (TL). During the season, running performance was monitored using the YoYo Recovery Test Level-2 (YYRT2) and lower body power performance using the drop jump (DJ) test. Changes in hematological, endocrine and muscle damage parameters were examined through 3 blood samples taken at separate times throughout the season. TL progressively and significantly (p < 0.001) decreased throughout the season particularly due to the decrease in the training volume. The last blood sample of the season revealed a significant (p < 0.001) increase in hematological parameters and a significant increase (p < 0.01) in cortisol blood concentration without change in the testosterone/cortisol ratio. No significant change in YYRT2 performance was observed over the season, while DJ test performance was significantly lower during the first 2 blocks of the season compared to other blocks. The training volume showed a significant negative correlation with DJ-test performances (TD: r = -0.49 and S-RPE: r = -0.40, p < 0.001). Although there was a decrease in training volume throughout the season, there was no significant changes in running performance. Furthermore, lower body power production showed a significant increase in particular during the last part of the season
Fresnel diffraction in an interferometer: application to MATISSE
While doing optical study in an instrument similar to the interferometers
dedicated to the Very Large Telescope (VLT), we have to take care of the pupil
and focus conjugations. Modules with artificial sources are designed to
simulate the stellar beams, in terms of collimation and pupil location. They
constitute alignment and calibration tools. In this paper, we present such a
module in which the pupil mask is not located in a collimated beam thus
introducing Fresnel diffraction. We study the instrumental contrast taking into
account the spatial coherence of the source, and the pupil diffraction. The
considered example is MATISSE, but this study can apply to any other instrument
concerned with Fresnel diffraction.Comment: 8 pages- to appear in Proceedings of SPIE Astronomical Telescopes and
Instrumentation 201
Applicability of in vivo staging of regional amyloid burden in a cognitively normal cohort with subjective memory complaints: the INSIGHT-preAD study.
BACKGROUND:Current methods of amyloid PET interpretation based on the binary classification of global amyloid signal fail to identify early phases of amyloid deposition. A recent analysis of 18F-florbetapir PET data from the Alzheimer's disease Neuroimaging Initiative cohort suggested a hierarchical four-stage model of regional amyloid deposition that resembles neuropathologic estimates and can be used to stage an individual's amyloid burden in vivo. Here, we evaluated the validity of this in vivo amyloid staging model in an independent cohort of older people with subjective memory complaints (SMC). We further examined its potential association with subtle cognitive impairments in this population at elevated risk for Alzheimer's disease (AD). METHODS:The monocentric INSIGHT-preAD cohort includes 318 cognitively intact older individuals with SMC. All individuals underwent 18F-florbetapir PET scanning and extensive neuropsychological testing. We projected the regional amyloid uptake signal into the previously proposed hierarchical staging model of in vivo amyloid progression. We determined the adherence to this model across all cases and tested the association between increasing in vivo amyloid stage and cognitive performance using ANCOVA models. RESULTS:In total, 156 participants (49%) showed evidence of regional amyloid deposition, and all but 2 of these (99%) adhered to the hierarchical regional pattern implied by the in vivo amyloid progression model. According to a conventional binary classification based on global signal (SUVRCereb = 1.10), individuals in stages III and IV were classified as amyloid-positive (except one in stage III), but 99% of individuals in stage I and even 28% of individuals in stage II were classified as amyloid-negative. Neither in vivo amyloid stage nor conventional binary amyloid status was significantly associated with cognitive performance in this preclinical cohort. CONCLUSIONS:The proposed hierarchical staging scheme of PET-evidenced amyloid deposition generalizes well to data from an independent cohort of older people at elevated risk for AD. Future studies will determine the prognostic value of the staging approach for predicting longitudinal cognitive decline in older individuals at increased risk for AD
Early Brain Activity Relates to Subsequent Brain Growth in Premature Infants
Recent experimental studies have shown that early brain activity is crucial for neuronal survival and the development of brain networks; however, it has been challenging to assess its role in the developing human brain. We employed serial quantitative magnetic resonance imaging to measure the rate of growth in circumscribed brain tissues from preterm to term age, and compared it with measures of electroencephalographic (EEG) activity during the first postnatal days by 2 different methods. EEG metrics of functional activity were computed: EEG signal peak-to-peak amplitude and the occurrence of developmentally important spontaneous activity transients (SATs). We found that an increased brain activity in the first postnatal days correlates with a faster growth of brain structures during subsequent months until term age. Total brain volume, and in particular subcortical gray matter volume, grew faster in babies with less cortical electrical quiescence and with more SAT events. The present findings are compatible with the idea that (1) early cortical network activity is important for brain growth, and that (2) objective measures may be devised to follow early human brain activity in a biologically reasoned way in future research as well as during intensive care treatmen
Study of the atmospheric refraction in a single mode instrument - Application to AMBER/VLTI
International audienceThis paper presents a study of the atmospheric refraction and its effect on the light coupling efficiency in an instrument using single-mode optical fibers. We show the analytical approach which allowed us to assess the need to correct the refraction in J- and H-bands while observing with an 8-m Unit Telescope. We then developed numerical simulations to go further in calculations. The hypotheses on the instrumental characteristics are those of AMBER (Astronomical Multi BEam combineR), the near infrared focal beam combiner of the Very Large Telescope Interferometric mode (VLTI), but most of the conclusions can be generalized to other single-mode instruments. We used the software package caos (Code for Adaptive Optics Systems) to take into account the atmospheric turbulence effect after correction by the ESO system MACAO (Multi-Application Curvature Adaptive Optics). The opto-mechanical study and design of the system correcting the atmospheric refraction on AMBER is then detailed. We showed that the atmospheric refraction becomes predominant over the atmospheric turbulence for some zenith angles z and spectral conditions: for z larger than 30° in J-band for example. The study of the optical system showed that it allows to achieve the required instrumental performance in terms of throughput in J- and H-bands. First observations in J-band of a bright star, alpha Cir star, at more than 30° from zenith clearly showed the gain to control the atmospheric refraction in a single mode instrument, and validated the operating law
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