23 research outputs found
Dynamical quark loop light-by-light contribution to muon g-2 within the nonlocal chiral quark model
Nonperturbative contributions to the quark form factor at high energy
The analysis of nonperturbative effects in high energy asymptotics of the
electomagnetic quark form factor is presented. It is shown that the
nonperturbative effects determine the initial value for the perturbative
evolution of the quark form factor and find their general structure with
respect to the high energy asymptotics. Within the Wilson integral formalism
which is natural for investigation of the soft, IR sensitive, part of the
factorized form factor, the structure of the instanton induced effects in the
evolution equation is discussed. It is demonstrated that the instanton
contributions result in the finite renormalization of the subleading
perturbative result and numerically are characterized by small factor
reflecting the diluteness of the QCD vacuum within the instanton liquid model.
The relevance of the IR renormalon induced effects in high energy asymptotic
behaviour is discussed. The consequences of the various analytization
procedures of the strong coupling constant in the IR domain are considered.Comment: REVTeX, 12 pages, 1 figure. Important references and discussions
added, misprints corrected, minor changes in tex
Two-loop QED radiative corrections to the decay pi0 -> e+ e- : The virtual corrections and soft-photon bremsstrahlung
This paper is devoted to the two-loop QED radiative corrections to the decay
pi0 -> e+ e-. We compute the virtual corrections without using any
approximation and we take into account all the relevant graphs with the
inclusion of those omitted in the previous approximative calculations. The
bremsstrahlung is then treated within the soft photon approximation. We
concentrate on the technical aspects of the calculation and discuss in detail
the UV renormalization and the treatment of IR divergences within the
dimensional regularization. As a result we obtain the O(alpha^3 p^2)
contribution in closed analytic form. We compare the exact two-loop results
with existing approximative calculations of QED corrections and find
significant disagreement in the kinematical region relevant for the KTeV
experiment.Comment: 48 pages plus 4 appendices (72 pages total), 26 figures; v3: new
chapter 9 with phenomenological discussion added, references added, minor
typos corrected; coincides with the journal versio
Weinberg like sum rules revisited
The generalized Weinberg sum rules containing the difference of isovector
vector and axial-vector spectral functions saturated by both finite and
infinite number of narrow resonances are considered. We summarize the status of
these sum rules and analyze their overall agreement with phenomenological
Lagrangians, low-energy relations, parity doubling, hadron string models, and
experimental data.Comment: 31 pages, noticed misprints are corrected, references are added, and
other minor corrections are mad
Low Cost Tuberculosis Vaccine Antigens in Capsules: Expression in Chloroplasts, Bio-Encapsulation, Stability and Functional Evaluation In Vitro
Tuberculosis (TB) caused by Mycobacterium tuberculosis is one of the leading fatal infectious diseases. The development of TB vaccines has been recognized as a major public health priority by the World Health Organization. In this study, three candidate antigens, ESAT-6 (6kDa early secretory antigenic target) and Mtb72F (a fusion polyprotein from two TB antigens, Mtb32 and Mtb39) fused with cholera toxin B-subunit (CTB) and LipY (a cell wall protein) were expressed in tobacco and/or lettuce chloroplasts to facilitate bioencapsulation/oral delivery. Site-specific transgene integration into the chloroplast genome was confirmed by Southern blot analysis. In transplastomic leaves, CTB fusion proteins existed in soluble monomeric or multimeric forms of expected sizes and their expression levels varied depending upon the developmental stage and time of leaf harvest, with the highest-level of accumulation in mature leaves harvested at 6PM. The CTB-ESAT6 and CTB-Mtb72F expression levels reached up to 7.5% and 1.2% of total soluble protein respectively in mature tobacco leaves. Transplastomic CTB-ESAT6 lettuce plants accumulated up to 0.75% of total leaf protein. Western blot analysis of lyophilized lettuce leaves stored at room temperature for up to six months showed that the CTB-ESAT6 fusion protein was stable and preserved proper folding, disulfide bonds and assembly into pentamers for prolonged periods. Also, antigen concentration per gram of leaf tissue was increased 22 fold after lyophilization. Hemolysis assay with purified CTB-ESAT6 protein showed partial hemolysis of red blood cells and confirmed functionality of the ESAT-6 antigen. GM1-binding assay demonstrated that the CTB-ESAT6 fusion protein formed pentamers to bind with the GM1-ganglioside receptor. The expression of functional Mycobacterium tuberculosis antigens in transplastomic plants should facilitate development of a cost-effective and orally deliverable TB booster vaccine with potential for long-term storage at room temperature. To our knowledge, this is the first report of expression of TB vaccine antigens in chloroplasts
The anomalous magnetic moment of the muon in the Standard Model
194 pages, 103 figures, bib files for the citation references are available from: https://muon-gm2-theory.illinois.eduWe review the present status of the Standard Model calculation of the anomalous magnetic moment of the muon. This is performed in a perturbative expansion in the fine-structure constant and is broken down into pure QED, electroweak, and hadronic contributions. The pure QED contribution is by far the largest and has been evaluated up to and including with negligible numerical uncertainty. The electroweak contribution is suppressed by and only shows up at the level of the seventh significant digit. It has been evaluated up to two loops and is known to better than one percent. Hadronic contributions are the most difficult to calculate and are responsible for almost all of the theoretical uncertainty. The leading hadronic contribution appears at and is due to hadronic vacuum polarization, whereas at the hadronic light-by-light scattering contribution appears. Given the low characteristic scale of this observable, these contributions have to be calculated with nonperturbative methods, in particular, dispersion relations and the lattice approach to QCD. The largest part of this review is dedicated to a detailed account of recent efforts to improve the calculation of these two contributions with either a data-driven, dispersive approach, or a first-principle, lattice-QCD approach. The final result reads and is smaller than the Brookhaven measurement by 3.7. The experimental uncertainty will soon be reduced by up to a factor four by the new experiment currently running at Fermilab, and also by the future J-PARC experiment. This and the prospects to further reduce the theoretical uncertainty in the near future-which are also discussed here-make this quantity one of the most promising places to look for evidence of new physics