Tsunami vulnerability assessment and its implications for coastal hazard analysis and disaster management planning, Gulf of Corinth, Greece

International audienceWe apply a new tsunami vulnerability assessment method to two coastal villages in the Gulf of Corinth, Greece using the 7th February 1963 tsunami as a worse case scenario. In Akoli, 46.5% of all buildings are classified highly vulnerable (BV). Approximately, 26.3% of all households are located within buildings with a High BV classification whereas 85% of all businesses are located within buildings with a High BV classification and 13.7% of the population is located within buildings with a High BV classification. In Selianitika, 28.8% of all buildings are classified with a High BV and 11% of all households are located within buildings with a High BV classification. Also 29.3% of all businesses and 33.4% of all services are located within buildings with a High BV classification and 6.7% of the population is located within buildings with a High BV classification. We estimate the minimum costs of a hypothetical tsunami with a wave run-up (H(m)max) of + 5 m. The results are considered significant because they have important implications for coastal risk assessment, resource allocation and disaster management planning

Why emergency management should be interested in the emergence of antibiotic resistance

Bacterial epidemics and pandemics are biological risks to life every bit as significant as floods, fires, storms and earthquakes. Antibiotics have been a significant tool in the management of epidemics and pandemics (as well as for fighting general infections) since their discovery in the 1930s. Due to the development of antibiotic resistance by bacteria, we are now approaching a post-antibiotic era where our capacity to manage infectious disease, particularly bacterial epidemics and pandemics, is compromised. Despite considerable efforts by global heath organisations, we need new ways of thinking and acting on the global risk of antibiotic resistance. We argue for a rebranding of the issue to one of a disaster risk and suggest the use of the risk management process and expertise of emergency management to present a new way of thinking about this globally significant risk to life

Assessing the vulnerability of buildings to tsunami in Sydney

Australia is vulnerable to the impacts of tsunamis and exposure along the SE coast of New South Wales is especially high. Significantly, this is the same area reported to have been affected by repeated large magnitude tsunamis during the Holocene. Efforts are under way to complete probabilistic risk assessments for the region but local government planners and emergency risk managers need information now about building vulnerability in order to develop appropriate risk management strategies. We use the newly revised PTVA-3 Model (Dall'Osso et al., 2009) to assess the relative vulnerability of buildings to damage from a "worst case tsunami" defined by our latest understanding of regional risk – something never before undertaken in Australia. We present selected results from an investigation of building vulnerability within the local government area of Manly – an iconic coastal area of Sydney. We show that a significant proportion of buildings (in particular, residential structures) are classified as having "High" and "Very High" Relative Vulnerability Index scores. Furthermore, other important buildings (e.g., schools, nursing homes and transport structures) are also vulnerable to damage. Our results have serious implications for immediate emergency risk management, longer-term land-use zoning and development, and building design and construction standards. Based on the work undertaken here, we recommend further detailed assessment of the vulnerability of coastal buildings in at risk areas, development of appropriate risk management strategies and a detailed program of community engagement to increase overall resilience

Elements at risk as a framework for assessing the vulnerability of communities to landslides

International audienceThe assessment of the vulnerability of communities prone to landslide related disasters is a topic that is growing in importance. Few studies discuss this issue and limited research has been carried out on the relationship between types of landslide and their potential impact on buildings and infrastructure. We outline a framework to undertake an assessment of the vulnerability of buildings to landslide utilising a similar framework used for assessing the vulnerability of buildings to tsunami damage. The framework is based on the development of an "elements at risk database" that takes into consideration the characteristics and use of the buildings, their importance for the local economy and the characteristics of the inhabitants (population density, age and so forth). The attributes that affect vulnerability are imported and examined within a GIS database which is used to visualise the physical, human and economic vulnerability. The results may have important implications for disaster management and emergency planning, and the database can be used by various end-users and stakeholders such as insurance companies, local authorities and the emergency services. The approach presented here can be integrated in to a wider more detailed "Framework for Landslide Risk and Vulnerability Assessment for Communities". We illustrate the potential of this framework and present preliminary results from Lichtenstein, Baden Württemberg, Germany

Corrigendum to "A revised (PTVA) model for assessing the vulnerability of buildings to tsunami damage" published in Nat. Hazards Earth Syst. Sci., 9, 1557–1565, 2009"

No abstract available

Transgenic models of skin diseases

Background: Transgenic animals have greatly enhanced our understanding of the contribution of various structural and regulatory components to epidermal biology. The expression of mutant versions of these components in the epidermis of transgenic mice has generated animal models of specific human skin diseases

Synthetic and computational studies on the tricarboxylate core of 6,7-dideoxysqualestatin H5 involving a carbonyl ylide cycloaddition–rearrangement

Reaction of diazodiketoesters 17 and 28 with methyl glyoxylate in the presence of catalytic rhodium(II) acetate generates predominantly the 6,8-dioxabicyclo[3.2.1]octanes 29 and 30, respectively. Acid-catalysed rearrangement of the corresponding alcohol 31 favours, at equilibrium, the 2,8-dioxabicyclo[3.2.1]octane skeleton 33 of the squalestatins–zaragozic acids. Force field calculations on the position of the equilibrium gave misleading results. DFT calculations were correct in suggesting that the energy difference between 31 and 33 should be small, but did not always suggest the right major product. Calculation of the NMR spectra of the similar structures could be used to assign the isomers with a high level of confidence