539 research outputs found
Quantum Theory and Time Asymmetry
The relation between quantum measurement and thermodynamically irreversible
processes is investigated. The reduction of the state vector is fundamentally
asymmetric in time and shows an observer-relatedness which may explain the
double interpretation of the state vector as a representation of physical
states as well as of information about them. The concept of relevance being
used in all statistical theories of irreversible thermodynamics is shown to be
based on the same observer-relatedness. Quantum theories of irreversible
processes implicitly use an objectivized process of state vector reduction. The
conditions for the reduction are discussed, and I speculate that the final
(subjective) observer system might even be carried by a spacetime point.Comment: Latex version of a paper published in 1979 (with minor revisions), 18
page
Earthquake Occurrence in Geometrical Complex Systems
Earthquake Occurrence in Geometrical Complex
System
Prediction of Anisotropic Single-Dirac-Cones in BiSb Thin Films
The electronic band structures of BiSb thin films can be
varied as a function of temperature, pressure, stoichiometry, film thickness
and growth orientation. We here show how different anisotropic
single-Dirac-cones can be constructed in a BiSb thin film for
different applications or research purposes. For predicting anisotropic
single-Dirac-cones, we have developed an iterative-two-dimensional-two-band
model to get a consistent inverse-effective-mass-tensor and band-gap, which can
be used in a general two-dimensional system that has a non-parabolic dispersion
relation as in a BiSb thin film system
A boron-coated CCD camera for direct detection of Ultracold Neutrons (UCN)
A new boron-coated CCD camera is described for direct detection of ultracold
neutrons (UCN) through the capture reactions B
(n,0)Li (6%) and B(n,1)Li (94%).
The experiments, which extend earlier works using a boron-coated ZnS:Ag
scintillator, are based on direct detections of the neutron-capture byproducts
in silicon. The high position resolution, energy resolution and particle ID
performance of a scientific CCD allows for observation and identification of
all the byproducts , Li and (electron recoils). A
signal-to-noise improvement on the order of 10 over the indirect method has
been achieved. Sub-pixel position resolution of a few microns is demonstrated.
The technology can also be used to build UCN detectors with an area on the
order of 1 m. The combination of micrometer scale spatial resolution, few
electrons ionization thresholds and large area paves the way to new research
avenues including quantum physics of UCN and high-resolution neutron imaging
and spectroscopy.Comment: 10 pages, 8 figure
Kentucky UST Field Manual
This study was undertaken to address the removal and closure of defective petroleum underground storage tanks in Kentucky. Goals for the study included: To address standards for levels of contamination requiring corrective action consistent with accepted scientific and technical principles. To recommend a matrix or scoring system to be used for (a) ranking sites as to actual or potential harm to human health and the environment caused by release of petroleum from a petroleum storage tank, and (2) establishing standards and procedures for corrective action that shall adequately protect human health and the environment. To address all compounds individually and collectively known as petroleum. To produce a report that shall be scientifically defensible
Status Report: Identification of Appropriate Standards for Corrective Action for a Release from Petroleum Underground Storage Tanks, Volume 1
This study was undertaken to address the removal and closure of defective petroleum underground storage tanks in Kentucky: To address standards for levels of contamination requiring corrective action consistent with accepted scientific and technical principles. To recommend a matrix or scoring system to be used for (a) ranking sites as to actual or potential harm to human health and the environment caused by a release of petroleum from a petroleum storage tank, and (b) establishing standards and procedures for corrective action that shall adequately protect human health and the environment. To address all compounds individually and collectively known as petroleum. To produce a report that shall be scientifically defensible
Optical properties of (AlxGa1−x)0.52In0.48P at the crossover from a direct-gap to an indirect-gap semiconductor
The optical properties and the dynamics of excitons and the electron-hole plasma have been studied in disordered (AlxGa1−x)0.52In0.48P near to the direct-to-indirect band gap crossover. In particular we have investigated three epitaxial layers grown by solid-source molecular beam epitaxy with varying Al content x. Two of them have compositions in the immediate vicinity of the crossover point, the other is assigned to the indirect-gap regime. Both direct and indirect recombination processes contribute to the photon emission from the material. Since the relative importance of the different recombination processes depends strongly on temperature, excitation intensity, and excitation pulse duration, the processes can be identified by changing these parameters. As a result, we can determine the relative alignment of the conduction band minima and the distribution of the electrons among them. At high excitation levels the two crossover samples show stimulated emission at a photon energy of ∼2.29 eV, i.e., in the green spectral range. Using the variable stripe length method, we find an optical gain of up to ∼600 cm−1 at excitation levels of ∼350 kW/cm2.Stimulated emission involves direct recombination. This conclusion is reached from the experiments and from line-shape modeling, including a self-consistent treatment of populations and renormalization of the conduction band minima
The Reality of Pervasive Transcription
Despite recent controversies, the evidence that the majority of the human genome is transcribed into RNA remains strong
Quantifying decoherence in continuous variable systems
We present a detailed report on the decoherence of quantum states of
continuous variable systems under the action of a quantum optical master
equation resulting from the interaction with general Gaussian uncorrelated
environments. The rate of decoherence is quantified by relating it to the decay
rates of various, complementary measures of the quantum nature of a state, such
as the purity, some nonclassicality indicators in phase space and, for two-mode
states, entanglement measures and total correlations between the modes.
Different sets of physically relevant initial configurations are considered,
including one- and two-mode Gaussian states, number states, and coherent
superpositions. Our analysis shows that, generally, the use of initially
squeezed configurations does not help to preserve the coherence of Gaussian
states, whereas it can be effective in protecting coherent superpositions of
both number states and Gaussian wave packets.Comment: Review article; 36 pages, 19 figures; typos corrected, references
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Integrating exome sequencing into a diagnostic pathway for epileptic encephalopathy: Evidence of clinical utility and cost effectiveness
© 2017 The Authors. Molecular Genetics & Genomic Medicine published by Wiley Periodicals, Inc. Background: Epileptic encephalopathies are a devastating group of neurological conditions in which etiological diagnosis can alter management and clinical outcome. Exome sequencing and gene panel testing can improve diagnostic yield but there is no cost-effectiveness analysis of their use or consensus on how to best integrate these tests into clinical diagnostic pathways. Methods: We conducted a retrospective cost-effectiveness study comparing trio exome sequencing with a standard diagnostic approach, for a well-phenotyped cohort of 32 patients with epileptic encephalopathy, who remained undiagnosed after “first-tier” testing. Sensitivity analysis was included with a range of commercial exome and multigene panels. Results: The diagnostic yield was higher for the exome sequencing (16/32; 50%) than the standard arm (2/32; 6.2%). The trio exome sequencing pathway was cost-effective compared to the standard diagnostic pathway with a cost saving of AU2,482; $9,784) per additional diagnosis; the standard pathway cost approximately 10 times more per diagnosis. Sensitivity analysis demonstrated that the majority of commercial exome sequencing and multigene panels studied were also cost-effective. The clinical utility of all diagnoses was reported. Conclusion: Our study supports the integration of exome sequencing and gene panel testing into the diagnostic pathway for epileptic encephalopathy, both in terms of cost effectiveness and clinical utility. We propose a diagnostic pathway that integrates initial rapid screening for treatable causes and comprehensive genomic screening. This study has important implications for health policy and public funding for epileptic encephalopathy and other neurological conditions
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