919 research outputs found
A Federation of Language Archives Enabling Future eHumanities Scenarios
This paper describes the need for new infrastructures for future eScience scenarios in the humanities. Three projects working on different aspects of these infrastructures are examined in detail. The first project is trying to achieve a federation of archives, developing an integration layer at the level of localization, access to and referring to an archive’s raw data objects. The other two try to achieve interoperability at the level of semantic interpretation of linguistic data-types and tagging systems. The project’s different approaches to this problem show the trade-of between flexibility and the user’s workload. All three approaches give an impression about the necessary steps to come to an eHumanities scenario
Using late-time optical and near-infrared spectra to constrain Type Ia supernova explosion properties
The late-time spectra of Type Ia supernovae (SNe Ia) are powerful probes of
the underlying physics of their explosions. We investigate the late-time
optical and near-infrared spectra of seven SNe Ia obtained at the VLT with
XShooter at 200 d after explosion. At these epochs, the inner Fe-rich ejecta
can be studied. We use a line-fitting analysis to determine the relative line
fluxes, velocity shifts, and line widths of prominent features contributing to
the spectra ([Fe II], [Ni II], and [Co III]). By focussing on [Fe II] and [Ni
II] emission lines in the ~7000-7500 \AA\ region of the spectrum, we find that
the ratio of stable [Ni II] to mainly radioactively-produced [Fe II] for most
SNe Ia in the sample is consistent with Chandrasekhar-mass delayed-detonation
explosion models, as well as sub-Chandrasekhar mass explosions that have
metallicity values above solar. The mean measured Ni/Fe abundance of our sample
is consistent with the solar value. The more highly ionised [Co III] emission
lines are found to be more centrally located in the ejecta and have broader
lines than the [Fe II] and [Ni II] features. Our analysis also strengthens
previous results that SNe Ia with higher Si II velocities at maximum light
preferentially display blueshifted [Fe II] 7155 \AA\ lines at late times. Our
combined results lead us to speculate that the majority of normal SN Ia
explosions produce ejecta distributions that deviate significantly from
spherical symmetry.Comment: 17 pages, 12 figure, accepted for publication in MNRA
Stability of the non-extremal enhancon solution I: perturbation equations
We consider the stability of the two branches of non-extremal enhancon
solutions. We argue that one would expect a transition between the two branches
at some value of the non-extremality, which should manifest itself in some
instability. We study small perturbations of these solutions, constructing a
sufficiently general ansatz for linearised perturbations of the non-extremal
solutions, and show that the linearised equations are consistent. We show that
the simplest kind of perturbation does not lead to any instability. We reduce
the problem of studying the more general spherically symmetric perturbation to
solving a set of three coupled second-order differential equations.Comment: 20 pages, 1 figure, references added, typos fixed, version to appear
in PR
Microsecond folding dynamics of the F13W G29A mutant of the B domain of staphylococcal protein A by laser-induced temperature jump
The small size (58 residues) and simple structure of the B domain of staphylococcal protein A (BdpA) have led to this domain being a paradigm for theoretical studies of folding. Experimental studies of the folding of BdpA have been limited by the rapidity of its folding kinetics. We report the folding kinetics of a fluorescent mutant of BdpA (G29A F13W), named F13W*, using nanosecond laser-induced temperature jump experiments. Automation of the apparatus has permitted large data sets to be acquired that provide excellent signal-to-noise ratio over a wide range of experimental conditions. By measuring the temperature and denaturant dependence of equilibrium and kinetic data for F13W*, we show that thermodynamic modeling of multidimensional equilibrium and kinetic surfaces is a robust method that allows reliable extrapolation of rate constants to regions of the folding landscape not directly accessible experimentally. The results reveal that F13W* is the fastest-folding protein of its size studied to date, with a maximum folding rate constant at 0 M guanidinium chloride and 45°C of 249,000 (s-1). Assuming the single-exponential kinetics represent barrier-limited folding, these data limit the value for the preexponential factor for folding of this protein to at least ≈2 x 10(6) s(-1)
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